PL2214491T3 - Analogi chinolonów i związane z nimi sposoby - Google Patents

Analogi chinolonów i związane z nimi sposoby

Info

Publication number
PL2214491T3
PL2214491T3 PL08835342.0T PL08835342T PL2214491T3 PL 2214491 T3 PL2214491 T3 PL 2214491T3 PL 08835342 T PL08835342 T PL 08835342T PL 2214491 T3 PL2214491 T3 PL 2214491T3
Authority
PL
Poland
Prior art keywords
methods related
quinolone analogs
quinolone
analogs
methods
Prior art date
Application number
PL08835342.0T
Other languages
English (en)
Inventor
Johnny Yasuo Nagasawa
Fabrice Pierre
Mustapha Haddach
Michael Schwaebe
Levan Darjania
Jeffrey P. Whitten
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of PL2214491T3 publication Critical patent/PL2214491T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains three hetero rings
    • C07D513/14—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/06—Peri-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D498/16—Peri-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Epidemiology (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)
PL08835342.0T 2007-10-05 2008-10-03 Analogi chinolonów i związane z nimi sposoby PL2214491T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US97804207P 2007-10-05 2007-10-05
US3868108P 2008-03-21 2008-03-21
US4593308P 2008-04-17 2008-04-17

Publications (1)

Publication Number Publication Date
PL2214491T3 true PL2214491T3 (pl) 2016-11-30

Family

ID=40523786

Family Applications (2)

Application Number Title Priority Date Filing Date
PL08835342.0T PL2214491T3 (pl) 2007-10-05 2008-10-03 Analogi chinolonów i związane z nimi sposoby
PL16171555T PL3092901T3 (pl) 2007-10-05 2008-10-03 Analogi chinolonu i sposoby z nimi związane

Family Applications After (1)

Application Number Title Priority Date Filing Date
PL16171555T PL3092901T3 (pl) 2007-10-05 2008-10-03 Analogi chinolonu i sposoby z nimi związane

Country Status (19)

Country Link
US (2) US7928100B2 (pl)
EP (2) EP3092901B1 (pl)
JP (2) JP5824213B2 (pl)
KR (2) KR101682867B1 (pl)
CN (1) CN101888780B (pl)
AU (1) AU2008308485B2 (pl)
BR (1) BRPI0817806A2 (pl)
CA (1) CA2701630C (pl)
DK (1) DK3092901T3 (pl)
ES (2) ES2791305T3 (pl)
HK (1) HK1150728A1 (pl)
IL (2) IL204844A (pl)
MX (1) MX2010003685A (pl)
NO (1) NO20100596L (pl)
NZ (1) NZ584892A (pl)
PL (2) PL2214491T3 (pl)
PT (2) PT3092901T (pl)
RU (1) RU2549895C2 (pl)
WO (1) WO2009046383A1 (pl)

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US20110065687A1 (en) * 2007-04-17 2011-03-17 Michael Schwaebe Hydrazide compounds and uses thereof
NZ584892A (en) * 2007-10-05 2012-06-29 Cylene Pharmaceuticals Inc Quinolone analogs and methods related thereto
ES2432315T3 (es) 2009-08-28 2013-12-02 Takeda Pharmaceutical Company Limited Compuestos de hexahidrooxazinopterina para su uso como inhibidores de mTOR
US8293925B2 (en) * 2009-09-21 2012-10-23 Chemocentryx, Inc. Pyrrolidinone carboxamide derivatives
US8791107B2 (en) 2011-02-25 2014-07-29 Takeda Pharmaceutical Company Limited N-substituted oxazinopteridines and oxazinopteridinones
EP2685976B1 (en) 2011-03-17 2017-12-27 Tel HaShomer Medical Research Infrastructure and Services Ltd. Quinolone analogs for treating autoimmune diseases
GB201206384D0 (en) * 2012-04-11 2012-05-23 Redx Pharma Ltd Antibacterial drug derivatives
CN104177379B (zh) * 2013-05-22 2016-12-28 中国科学院上海药物研究所 一种喹诺酮类化合物或其立体化学异构体、包含该化合物的药物组合物及其用途
CA2925698C (en) 2013-11-28 2021-11-09 Tel Hashomer Medical Research Infrastructure And Services Ltd. Rna polymerase i inhibitors and uses thereof
US9758518B2 (en) 2015-03-04 2017-09-12 Pimera, Inc. Compositions, uses and methods for making them
JP6188179B2 (ja) * 2014-05-09 2017-08-30 ピメラ， インコーポレイテッド 新規組成物、使用およびそれを作製する方法
CA3005730A1 (en) * 2015-11-20 2017-05-26 Senhwa Biosciences, Inc. Combination therapy of tetracyclic quinolone analogs for treating cancer
US9957282B2 (en) * 2015-12-14 2018-05-01 Senhwa Biosciences, Inc. Crystalline forms of quinolone analogs and their salts
TWI765848B (zh) * 2015-12-14 2022-06-01 生華生物科技股份有限公司 喹諾酮類似物及其鹽的結晶形式
JP2018537486A (ja) * 2015-12-14 2018-12-20 センワ バイオサイエンシズ インコーポレイテッド キノロン類似体及びその塩の結晶形
WO2018183540A1 (en) 2017-03-28 2018-10-04 Pimera, Inc. Novel crystal forms of a pol1 inhibitor
US11071727B2 (en) 2018-01-26 2021-07-27 Northwestern University Therapeutic targeting of proteolytic cleavage of the mixed lineage leukemia gene product (MLL1) by taspase1 using kinase inhibitors
WO2019168688A2 (en) * 2018-02-15 2019-09-06 Senhwa Biosciences, Inc. Quinolone analogs and their salts, compositions, and method for their use
WO2020051342A1 (en) * 2018-09-06 2020-03-12 Cornell University Methods for treating metastatic disease using ribosome biogenesis inhibitor cx 5461
TW202115091A (zh) * 2019-08-14 2021-04-16 生華生物科技股份有限公司 喹啉類似物之結晶型及其鹽類、組合物、及彼等之使用方法
WO2021030671A1 (en) * 2019-08-14 2021-02-18 Senhwa Biosciences, Inc. Tetracyclic compounds and their salts, compositions, and methods for their use
JP2020189888A (ja) * 2020-08-28 2020-11-26 センワ バイオサイエンシズ インコーポレイテッド キノロン類似体及びその塩の結晶形
CN114573604A (zh) * 2020-12-01 2022-06-03 中国科学院上海药物研究所 一类基于喹诺酮的化合物、其制备方法、包含其的药物组合物及其用途
WO2022198101A1 (en) 2021-03-19 2022-09-22 Trained Therapeutix Discovery, Inc. Compounds for regulating trained immunity, and their methods of use
CN114409681A (zh) * 2022-03-18 2022-04-29 信义核新(北京)生物科技有限公司 用于治疗dna损伤修复缺陷肿瘤的喹诺酮类似物及其应用

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US4559157A (en) 1983-04-21 1985-12-17 Creative Products Resource Associates, Ltd. Cosmetic applicator useful for skin moisturizing
LU84979A1 (fr) 1983-08-30 1985-04-24 Oreal Composition cosmetique ou pharmaceutique sous forme aqueuse ou anhydre dont la phase grasse contient un polyether oligomere et polyethers oligomeres nouveaux
US4820508A (en) 1987-06-23 1989-04-11 Neutrogena Corporation Skin protective composition
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JP4932994B2 (ja) 1999-04-07 2012-05-16 ユニバーシテイ・オブ・バージニア・パテント・フアウンデーシヨン 抗癌性カルシウムチャンネル遮断薬
WO2003050107A1 (en) * 2001-12-13 2003-06-19 Wockhardt Limited New generation triple-targeting, chiral, broad-spectrum antimicrobial 7-substituted piperidino-quinolone carboxylic acid derivatives, their preparation, compositions and use as medicaments
US6900224B2 (en) * 2002-07-31 2005-05-31 The Procter & Gamble Company Antimicrobial quinolones, their compositions and uses
SI1675852T1 (sl) * 2003-09-22 2009-06-30 Janssen Pharmaceutica Nv 7-amino alkilidenil-heterociklični kinoloni in naftiridoni
AU2005286965B2 (en) * 2004-09-17 2009-10-22 Senhwa Biosciences, Inc. Quinolone analogs as cell proliferation inhibitors
EP1928887B1 (en) * 2005-08-05 2014-12-17 Senhwa Biosciences, Inc. Methods of preparing quinolone analogs
US20070117770A1 (en) * 2005-08-19 2007-05-24 Cylene Pharmaceuticals, Inc. Human ribosomal DNA (rDNA) and ribosomal RNA (rRNA) nucleic acids and uses thereof
AR057555A1 (es) 2005-10-27 2007-12-05 Merck Frosst Canada Ltd Un inhibidor de fosfodiesterasa-4 4-oxo-1-(3-sustituido fenil-1,4-dihidro-1,8-naftiridin-3-carboxamida y un procedimiento de preparacion del mismo
US20090291437A1 (en) * 2005-11-02 2009-11-26 O'brien Sean Methods for targeting quadruplex sequences
US20100063046A1 (en) * 2006-05-17 2010-03-11 Whitten Jeffrey P Tetracyclic imidazole analogs
US20110112086A1 (en) 2006-06-08 2011-05-12 Cylene Pharmaceuticals, Inc. Pyridinone analogs
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NZ584892A (en) * 2007-10-05 2012-06-29 Cylene Pharmaceuticals Inc Quinolone analogs and methods related thereto

Also Published As

Publication number Publication date
CN101888780A (zh) 2010-11-17
KR20160020578A (ko) 2016-02-23
EP2214491A1 (en) 2010-08-11
KR101601332B1 (ko) 2016-03-08
KR101682867B1 (ko) 2016-12-05
JP5824213B2 (ja) 2015-11-25
CA2701630C (en) 2016-10-25
NZ584892A (en) 2012-06-29
CN101888780B (zh) 2014-08-13
JP2010540663A (ja) 2010-12-24
EP2214491A4 (en) 2010-11-10
IL249906B (en) 2020-10-29
EP3092901B1 (en) 2020-04-29
AU2008308485A1 (en) 2009-04-09
US7928100B2 (en) 2011-04-19
US20110218184A1 (en) 2011-09-08
US20090093455A1 (en) 2009-04-09
PT3092901T (pt) 2020-05-21
DK3092901T3 (da) 2020-05-18
PL3092901T3 (pl) 2020-10-19
IL204844A (en) 2017-01-31
CA2701630A1 (en) 2009-04-09
WO2009046383A1 (en) 2009-04-09
NO20100596L (no) 2010-06-10
PT2214491T (pt) 2016-10-25
BRPI0817806A2 (pt) 2014-10-07
RU2010117225A (ru) 2011-11-10
MX2010003685A (es) 2010-06-02
ES2791305T3 (es) 2020-11-03
ES2582662T3 (es) 2016-09-14
IL204844A0 (en) 2010-11-30
JP2014159474A (ja) 2014-09-04
EP2214491B1 (en) 2016-07-13
HK1150728A1 (en) 2012-01-13
AU2008308485B2 (en) 2014-08-07
IL249906A0 (en) 2017-03-30
RU2549895C2 (ru) 2015-05-10
EP3092901A1 (en) 2016-11-16
KR20100064392A (ko) 2010-06-14
US8853234B2 (en) 2014-10-07

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