DK3092901T3 - Quinolonanaloger og fremgangsmåder relateret dertil - Google Patents

Quinolonanaloger og fremgangsmåder relateret dertil Download PDF

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Publication number
DK3092901T3
DK3092901T3 DK16171555.2T DK16171555T DK3092901T3 DK 3092901 T3 DK3092901 T3 DK 3092901T3 DK 16171555 T DK16171555 T DK 16171555T DK 3092901 T3 DK3092901 T3 DK 3092901T3
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DK
Denmark
Prior art keywords
quinolon
analogs
procedures related
procedures
quinolon analogs
Prior art date
Application number
DK16171555.2T
Other languages
English (en)
Inventor
Johnny Yasuo Nagasawa
Fabrice Pierre
Mustapha Haddach
Michael Schwaebe
Levan Darjania
Jeffrey P Whitten
Original Assignee
Senhwa Biosciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Senhwa Biosciences Inc filed Critical Senhwa Biosciences Inc
Application granted granted Critical
Publication of DK3092901T3 publication Critical patent/DK3092901T3/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains three hetero rings
    • C07D513/14—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/06—Peri-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D498/16—Peri-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Virology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Epidemiology (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)
DK16171555.2T 2007-10-05 2008-10-03 Quinolonanaloger og fremgangsmåder relateret dertil DK3092901T3 (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US97804207P 2007-10-05 2007-10-05
US3868108P 2008-03-21 2008-03-21
US4593308P 2008-04-17 2008-04-17
EP08835342.0A EP2214491B1 (en) 2007-10-05 2008-10-03 Quinolone analogs and methods related thereto

Publications (1)

Publication Number Publication Date
DK3092901T3 true DK3092901T3 (da) 2020-05-18

Family

ID=40523786

Family Applications (1)

Application Number Title Priority Date Filing Date
DK16171555.2T DK3092901T3 (da) 2007-10-05 2008-10-03 Quinolonanaloger og fremgangsmåder relateret dertil

Country Status (19)

Country Link
US (2) US7928100B2 (da)
EP (2) EP3092901B1 (da)
JP (2) JP5824213B2 (da)
KR (2) KR101682867B1 (da)
CN (1) CN101888780B (da)
AU (1) AU2008308485B2 (da)
BR (1) BRPI0817806A2 (da)
CA (1) CA2701630C (da)
DK (1) DK3092901T3 (da)
ES (2) ES2791305T3 (da)
HK (1) HK1150728A1 (da)
IL (2) IL204844A (da)
MX (1) MX2010003685A (da)
NO (1) NO20100596L (da)
NZ (1) NZ584892A (da)
PL (2) PL3092901T3 (da)
PT (2) PT3092901T (da)
RU (1) RU2549895C2 (da)
WO (1) WO2009046383A1 (da)

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DK3092901T3 (da) * 2007-10-05 2020-05-18 Senhwa Biosciences Inc Quinolonanaloger og fremgangsmåder relateret dertil
JP2013503183A (ja) 2009-08-28 2013-01-31 武田薬品工業株式会社 ｍＴＯＲ阻害剤として使用するヘキサヒドロオキサジノプテリン化合物
WO2011035332A1 (en) * 2009-09-21 2011-03-24 Chemocentryx, Inc. Pyrrolidinone carboxamide derivatives as chemerin-r ( chemr23 ) modulators
JP5931933B2 (ja) 2011-02-25 2016-06-08 武田薬品工業株式会社 Ｎ−置換オキサジノプテリジンおよびオキサジノプテリジノン
EP2685976B1 (en) 2011-03-17 2017-12-27 Tel HaShomer Medical Research Infrastructure and Services Ltd. Quinolone analogs for treating autoimmune diseases
GB201206384D0 (en) * 2012-04-11 2012-05-23 Redx Pharma Ltd Antibacterial drug derivatives
CN104177379B (zh) * 2013-05-22 2016-12-28 中国科学院上海药物研究所 一种喹诺酮类化合物或其立体化学异构体、包含该化合物的药物组合物及其用途
EP3074391B1 (en) 2013-11-28 2019-07-31 Tel Hashomer Medical Research Infrastructure And Services Ltd. Rna polymerase i inhibitors and uses thereof
US9758518B2 (en) * 2015-03-04 2017-09-12 Pimera, Inc. Compositions, uses and methods for making them
DK3140305T3 (da) * 2014-05-09 2018-07-30 Pimera Inc Hidtil ukendte sammensætninger samt anvendelser og fremgangsmåder til fremstilling deraf
WO2017087235A1 (en) 2015-11-20 2017-05-26 Senhwa Biosciences, Inc. Combination therapy of tetracyclic quinolone analogs for treating cancer
US9957282B2 (en) 2015-12-14 2018-05-01 Senhwa Biosciences, Inc. Crystalline forms of quinolone analogs and their salts
WO2017105382A1 (en) 2015-12-14 2017-06-22 Ryckman David M Crystalline forms of quinolone analogs and their salts
TWI765848B (zh) * 2015-12-14 2022-06-01 生華生物科技股份有限公司 喹諾酮類似物及其鹽的結晶形式
CN110709400A (zh) 2017-03-28 2020-01-17 皮梅拉股份有限公司 Pol1抑制剂的新型晶体形式
US11071727B2 (en) 2018-01-26 2021-07-27 Northwestern University Therapeutic targeting of proteolytic cleavage of the mixed lineage leukemia gene product (MLL1) by taspase1 using kinase inhibitors
WO2019168688A2 (en) * 2018-02-15 2019-09-06 Senhwa Biosciences, Inc. Quinolone analogs and their salts, compositions, and method for their use
WO2020051342A1 (en) * 2018-09-06 2020-03-12 Cornell University Methods for treating metastatic disease using ribosome biogenesis inhibitor cx 5461
TW202115091A (zh) * 2019-08-14 2021-04-16 生華生物科技股份有限公司 喹啉類似物之結晶型及其鹽類、組合物、及彼等之使用方法
TW202114694A (zh) * 2019-08-14 2021-04-16 生華生物科技股份有限公司 四環化合物及其鹽類、組合物、及彼等之使用方法
JP2020189888A (ja) * 2020-08-28 2020-11-26 センワ バイオサイエンシズ インコーポレイテッド キノロン類似体及びその塩の結晶形
CN114573604B (zh) * 2020-12-01 2024-06-18 中国科学院上海药物研究所 一类基于喹诺酮的化合物、其制备方法、包含其的药物组合物及其用途
BR112023018950A2 (pt) 2021-03-19 2024-02-27 Icahn School Med Mount Sinai Composto, composições nanobiológica e farmacêutica, métodos para tratar um distúrbio de proliferação celular, para tratar sepse e para ativar um receptor nod2, processo para fabricação de uma composição nanobiológica e kit
CN114409681A (zh) * 2022-03-18 2022-04-29 信义核新(北京)生物科技有限公司 用于治疗dna损伤修复缺陷肿瘤的喹诺酮类似物及其应用

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DK3092901T3 (da) * 2007-10-05 2020-05-18 Senhwa Biosciences Inc Quinolonanaloger og fremgangsmåder relateret dertil

Also Published As

Publication number Publication date
US20090093455A1 (en) 2009-04-09
IL249906B (en) 2020-10-29
EP2214491A1 (en) 2010-08-11
KR101682867B1 (ko) 2016-12-05
CA2701630A1 (en) 2009-04-09
IL249906A0 (en) 2017-03-30
RU2010117225A (ru) 2011-11-10
PL3092901T3 (pl) 2020-10-19
JP2014159474A (ja) 2014-09-04
PL2214491T3 (pl) 2016-11-30
IL204844A (en) 2017-01-31
PT3092901T (pt) 2020-05-21
CN101888780A (zh) 2010-11-17
AU2008308485A1 (en) 2009-04-09
BRPI0817806A2 (pt) 2014-10-07
KR20100064392A (ko) 2010-06-14
MX2010003685A (es) 2010-06-02
EP3092901B1 (en) 2020-04-29
RU2549895C2 (ru) 2015-05-10
US8853234B2 (en) 2014-10-07
AU2008308485B2 (en) 2014-08-07
KR20160020578A (ko) 2016-02-23
PT2214491T (pt) 2016-10-25
IL204844A0 (en) 2010-11-30
CA2701630C (en) 2016-10-25
NZ584892A (en) 2012-06-29
US20110218184A1 (en) 2011-09-08
EP2214491A4 (en) 2010-11-10
US7928100B2 (en) 2011-04-19
CN101888780B (zh) 2014-08-13
JP5824213B2 (ja) 2015-11-25
HK1150728A1 (en) 2012-01-13
WO2009046383A1 (en) 2009-04-09
ES2791305T3 (es) 2020-11-03
JP2010540663A (ja) 2010-12-24
EP2214491B1 (en) 2016-07-13
KR101601332B1 (ko) 2016-03-08
NO20100596L (no) 2010-06-10
EP3092901A1 (en) 2016-11-16
ES2582662T3 (es) 2016-09-14

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