PL3092901T3 - Analogi chinolonu i sposoby z nimi związane - Google Patents

Analogi chinolonu i sposoby z nimi związane

Info

Publication number
PL3092901T3
PL3092901T3 PL16171555T PL16171555T PL3092901T3 PL 3092901 T3 PL3092901 T3 PL 3092901T3 PL 16171555 T PL16171555 T PL 16171555T PL 16171555 T PL16171555 T PL 16171555T PL 3092901 T3 PL3092901 T3 PL 3092901T3
Authority
PL
Poland
Prior art keywords
methods related
quinolone analogs
quinolone
analogs
methods
Prior art date
Application number
PL16171555T
Other languages
English (en)
Inventor
Johnny Yasuo Nagasawa
Fabrice Pierre
Mustapha Haddach
Michael Schwaebe
Levan Darjania
Jeffrey P. Whitten
Original Assignee
Senhwa Biosciences, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Senhwa Biosciences, Inc. filed Critical Senhwa Biosciences, Inc.
Publication of PL3092901T3 publication Critical patent/PL3092901T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains three hetero rings
    • C07D513/14—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/06—Peri-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D498/16—Peri-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Virology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Epidemiology (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)
PL16171555T 2007-10-05 2008-10-03 Analogi chinolonu i sposoby z nimi związane PL3092901T3 (pl)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US97804207P 2007-10-05 2007-10-05
US3868108P 2008-03-21 2008-03-21
US4593308P 2008-04-17 2008-04-17
PCT/US2008/078859 WO2009046383A1 (en) 2007-10-05 2008-10-03 Quinolone analogs and methods related thereto
EP08835342.0A EP2214491B1 (en) 2007-10-05 2008-10-03 Quinolone analogs and methods related thereto
EP16171555.2A EP3092901B1 (en) 2007-10-05 2008-10-03 Quinolone analogs and methods related thereto

Publications (1)

Publication Number Publication Date
PL3092901T3 true PL3092901T3 (pl) 2020-10-19

Family

ID=40523786

Family Applications (2)

Application Number Title Priority Date Filing Date
PL16171555T PL3092901T3 (pl) 2007-10-05 2008-10-03 Analogi chinolonu i sposoby z nimi związane
PL08835342.0T PL2214491T3 (pl) 2007-10-05 2008-10-03 Analogi chinolonów i związane z nimi sposoby

Family Applications After (1)

Application Number Title Priority Date Filing Date
PL08835342.0T PL2214491T3 (pl) 2007-10-05 2008-10-03 Analogi chinolonów i związane z nimi sposoby

Country Status (18)

Country Link
US (2) US7928100B2 (pl)
EP (2) EP2214491B1 (pl)
JP (2) JP5824213B2 (pl)
KR (2) KR101682867B1 (pl)
CN (1) CN101888780B (pl)
AU (1) AU2008308485B2 (pl)
BR (1) BRPI0817806A2 (pl)
CA (1) CA2701630C (pl)
DK (1) DK3092901T3 (pl)
ES (2) ES2791305T3 (pl)
IL (2) IL204844A (pl)
MX (1) MX2010003685A (pl)
NO (1) NO20100596L (pl)
NZ (1) NZ584892A (pl)
PL (2) PL3092901T3 (pl)
PT (2) PT3092901T (pl)
RU (1) RU2549895C2 (pl)
WO (1) WO2009046383A1 (pl)

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PL3092901T3 (pl) * 2007-10-05 2020-10-19 Senhwa Biosciences, Inc. Analogi chinolonu i sposoby z nimi związane
ES2432315T3 (es) 2009-08-28 2013-12-02 Takeda Pharmaceutical Company Limited Compuestos de hexahidrooxazinopterina para su uso como inhibidores de mTOR
EP2480531B1 (en) 2009-09-21 2014-11-05 ChemoCentryx, Inc. Pyrrolidinone carboxamide derivatives as chemerin-r (chemr23) modulators
CA2827770A1 (en) 2011-02-25 2012-11-01 Takeda Pharmaceutical Company Limited N-substituted oxazinopteridines and oxazinopteridinones
EP2685976B1 (en) 2011-03-17 2017-12-27 Tel HaShomer Medical Research Infrastructure and Services Ltd. Quinolone analogs for treating autoimmune diseases
GB201206384D0 (en) * 2012-04-11 2012-05-23 Redx Pharma Ltd Antibacterial drug derivatives
CN104177379B (zh) * 2013-05-22 2016-12-28 中国科学院上海药物研究所 一种喹诺酮类化合物或其立体化学异构体、包含该化合物的药物组合物及其用途
CA2925698C (en) 2013-11-28 2021-11-09 Tel Hashomer Medical Research Infrastructure And Services Ltd. Rna polymerase i inhibitors and uses thereof
PL3140305T3 (pl) * 2014-05-09 2018-10-31 Pimera, Inc. Nowe kompozycje, ich zastosowania i sposoby wytwarzania
US9758518B2 (en) 2015-03-04 2017-09-12 Pimera, Inc. Compositions, uses and methods for making them
WO2017087235A1 (en) 2015-11-20 2017-05-26 Senhwa Biosciences, Inc. Combination therapy of tetracyclic quinolone analogs for treating cancer
JP2018537486A (ja) * 2015-12-14 2018-12-20 センワ バイオサイエンシズ インコーポレイテッド キノロン類似体及びその塩の結晶形
US9957282B2 (en) 2015-12-14 2018-05-01 Senhwa Biosciences, Inc. Crystalline forms of quinolone analogs and their salts
TWI765848B (zh) * 2015-12-14 2022-06-01 生華生物科技股份有限公司 喹諾酮類似物及其鹽的結晶形式
EP4014967A1 (en) 2016-04-29 2022-06-22 Icahn School of Medicine at Mount Sinai Targeting the innate immunesystem to induce long-term tolerance and to resolve macrophage accumulation in atherosclerosis
CA3057741A1 (en) 2017-03-28 2018-10-04 Pimera, Inc. Novel crystal forms of a pol1 inhibitor
US11071727B2 (en) 2018-01-26 2021-07-27 Northwestern University Therapeutic targeting of proteolytic cleavage of the mixed lineage leukemia gene product (MLL1) by taspase1 using kinase inhibitors
TWI884912B (zh) 2018-02-15 2025-06-01 生華生物科技股份有限公司 喹啉酮類似物及其鹽、組合物及其使用方法
WO2020051342A1 (en) * 2018-09-06 2020-03-12 Cornell University Methods for treating metastatic disease using ribosome biogenesis inhibitor cx 5461
PH12022550360A1 (en) * 2019-08-14 2023-02-27 Senhwa Biosciences Inc Tetracyclic compounds and their salts, compositions, and methods for their use
BR112022002772A2 (pt) * 2019-08-14 2022-08-09 Senhwa Biosciences Inc Formas cristalinas de análogos de quinolina e sais dos mesmos, composições e seus métodos para uso
JP2020189888A (ja) * 2020-08-28 2020-11-26 センワ バイオサイエンシズ インコーポレイテッド キノロン類似体及びその塩の結晶形
US12274700B1 (en) 2020-10-30 2025-04-15 Accencio LLC Methods of treating symptoms of coronavirus infection with RNA polymerase inhibitors
CN114573604B (zh) * 2020-12-01 2024-06-18 中国科学院上海药物研究所 一类基于喹诺酮的化合物、其制备方法、包含其的药物组合物及其用途
CN118459539B (zh) 2021-03-19 2026-01-06 生物治疗探索股份有限公司 用于调节训练免疫的化合物及其使用方法
CN114409681A (zh) * 2022-03-18 2022-04-29 信义核新(北京)生物科技有限公司 用于治疗dna损伤修复缺陷肿瘤的喹诺酮类似物及其应用
EP4703364A1 (en) * 2023-04-23 2026-03-04 Horizon Omics Biotech Limited Quinolone analog and use thereof
WO2024222630A1 (zh) * 2023-04-23 2024-10-31 信义核新(北京)生物科技有限公司 喹诺酮衍生物及其在抗肿瘤中的应用
WO2025114459A1 (en) * 2023-11-28 2025-06-05 Genome Therapeutics Ltd Tetracyclic compounds for use in antibody-drug conjugates for the treatment of cancer
WO2025133338A1 (en) * 2023-12-21 2025-06-26 Genome Therapeutics Ltd Quinolone derivatves against cancer

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LU84979A1 (fr) 1983-08-30 1985-04-24 Oreal Composition cosmetique ou pharmaceutique sous forme aqueuse ou anhydre dont la phase grasse contient un polyether oligomere et polyethers oligomeres nouveaux
US4820508A (en) 1987-06-23 1989-04-11 Neutrogena Corporation Skin protective composition
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PL3092901T3 (pl) * 2007-10-05 2020-10-19 Senhwa Biosciences, Inc. Analogi chinolonu i sposoby z nimi związane

Also Published As

Publication number Publication date
ES2582662T3 (es) 2016-09-14
DK3092901T3 (da) 2020-05-18
JP2010540663A (ja) 2010-12-24
AU2008308485A1 (en) 2009-04-09
JP5824213B2 (ja) 2015-11-25
CA2701630C (en) 2016-10-25
IL249906B (en) 2020-10-29
IL204844A0 (en) 2010-11-30
CA2701630A1 (en) 2009-04-09
EP2214491A4 (en) 2010-11-10
RU2549895C2 (ru) 2015-05-10
KR101601332B1 (ko) 2016-03-08
BRPI0817806A2 (pt) 2014-10-07
US20090093455A1 (en) 2009-04-09
US20110218184A1 (en) 2011-09-08
KR101682867B1 (ko) 2016-12-05
EP3092901B1 (en) 2020-04-29
AU2008308485B2 (en) 2014-08-07
HK1150728A1 (en) 2012-01-13
CN101888780B (zh) 2014-08-13
EP2214491A1 (en) 2010-08-11
RU2010117225A (ru) 2011-11-10
KR20160020578A (ko) 2016-02-23
US7928100B2 (en) 2011-04-19
JP2014159474A (ja) 2014-09-04
WO2009046383A1 (en) 2009-04-09
IL249906A0 (en) 2017-03-30
MX2010003685A (es) 2010-06-02
ES2791305T3 (es) 2020-11-03
IL204844A (en) 2017-01-31
CN101888780A (zh) 2010-11-17
PT2214491T (pt) 2016-10-25
EP3092901A1 (en) 2016-11-16
PT3092901T (pt) 2020-05-21
NO20100596L (no) 2010-06-10
NZ584892A (en) 2012-06-29
PL2214491T3 (pl) 2016-11-30
US8853234B2 (en) 2014-10-07
KR20100064392A (ko) 2010-06-14
EP2214491B1 (en) 2016-07-13

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