HK1122806A1 - Bicyclic cinnamide compound - Google Patents
Bicyclic cinnamide compoundInfo
- Publication number
- HK1122806A1 HK1122806A1 HK08114015.4A HK08114015A HK1122806A1 HK 1122806 A1 HK1122806 A1 HK 1122806A1 HK 08114015 A HK08114015 A HK 08114015A HK 1122806 A1 HK1122806 A1 HK 1122806A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- cinnamide compound
- bicyclic
- bicyclic cinnamide
- compound
- cinnamide
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4178—1,3-Diazoles not condensed 1,3-diazoles and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2005337963 | 2005-11-24 | ||
| JP2006205538 | 2006-07-28 | ||
| PCT/JP2006/321877 WO2007060821A1 (ja) | 2005-11-24 | 2006-11-01 | ２環式シンナミド化合物 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HK1122806A1 true HK1122806A1 (en) | 2009-05-29 |
Family
ID=38067057
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HK08114015.4A HK1122806A1 (en) | 2005-11-24 | 2008-12-29 | Bicyclic cinnamide compound |
Country Status (26)
| Country | Link |
|---|---|
| US (1) | US8048878B2 (xx) |
| EP (1) | EP1953158B1 (xx) |
| JP (1) | JP5178203B2 (xx) |
| KR (1) | KR101296239B1 (xx) |
| AR (1) | AR057915A1 (xx) |
| AU (1) | AU2006317468B2 (xx) |
| BR (1) | BRPI0618890A2 (xx) |
| CA (1) | CA2629512C (xx) |
| CR (1) | CR9983A (xx) |
| EA (1) | EA014427B1 (xx) |
| EC (1) | ECSP088466A (xx) |
| ES (1) | ES2394364T3 (xx) |
| GE (1) | GEP20115172B (xx) |
| HK (1) | HK1122806A1 (xx) |
| HN (1) | HN2008000792A (xx) |
| MA (1) | MA29968B1 (xx) |
| ME (1) | ME00040B (xx) |
| MY (1) | MY144596A (xx) |
| NO (1) | NO20082805L (xx) |
| NZ (1) | NZ568422A (xx) |
| PE (1) | PE20071029A1 (xx) |
| PL (1) | PL1953158T3 (xx) |
| RS (1) | RS20080242A (xx) |
| SA (1) | SA06270432B1 (xx) |
| TW (1) | TWI370130B (xx) |
| WO (1) | WO2007060821A1 (xx) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1757591A4 (en) | 2004-05-26 | 2010-05-05 | Eisai R&D Man Co Ltd | ZIMTSÄUREAMIDVERBINDUNG |
| KR20070083781A (ko) | 2004-10-26 | 2007-08-24 | 에자이 알앤드디 매니지먼트 가부시키가이샤 | 신나미드 화합물의 비정질체 |
| TWI370130B (en) | 2005-11-24 | 2012-08-11 | Eisai R&D Man Co Ltd | Two cyclic cinnamide compound |
| NZ568050A (en) | 2005-11-24 | 2010-09-30 | Eisai R&D Man Co Ltd | Morpholine type cinnamide compound |
| US7482345B2 (en) * | 2005-12-05 | 2009-01-27 | Meng-Hsin Chen | P38 kinase inhibiting agents |
| TWI378091B (en) | 2006-03-09 | 2012-12-01 | Eisai R&D Man Co Ltd | Multi-cyclic cinnamide derivatives |
| AR062095A1 (es) | 2006-07-28 | 2008-10-15 | Eisai R&D Man Co Ltd | Profarmaco de compuesto cinamida |
| TW200848054A (en) * | 2007-02-28 | 2008-12-16 | Eisai R&D Man Co Ltd | Two cyclic oxomorpholine derivatives |
| US8426403B2 (en) * | 2007-06-01 | 2013-04-23 | Zhaoning Zhu | Gamma secretase modulators |
| JP5121346B2 (ja) * | 2007-08-07 | 2013-01-16 | 国立大学法人 長崎大学 | 光学活性プロリンエステル誘導体およびｎ−ホルミル光学活性プロリン誘導体の製造方法 |
| AR068121A1 (es) | 2007-08-31 | 2009-11-04 | Eisai R&D Man Co Ltd | Compuestos multiciclicos para tratar enfermedades neurodegenerativas |
| US7935815B2 (en) * | 2007-08-31 | 2011-05-03 | Eisai R&D Management Co., Ltd. | Imidazoyl pyridine compounds and salts thereof |
| CA2710485A1 (en) | 2007-12-26 | 2009-07-02 | Eisai R&D Management Co., Ltd. | Process for production of 4-(substituted phenyl)hexahydropyrido[2,1-c][1,4]oxazin-6-one |
| BRPI0907577A2 (pt) | 2008-02-22 | 2015-07-21 | Hoffmann La Roche | Moduladores para amiloide beta |
| JP5502089B2 (ja) | 2008-10-09 | 2014-05-28 | エフ．ホフマン−ラ ロシュ アーゲー | アミロイドβのモジュレーター |
| CA2742500A1 (en) * | 2008-11-06 | 2010-05-14 | Schering Corporation | Gamma secretase modulators |
| AU2009313538A1 (en) * | 2008-11-06 | 2010-05-14 | Merck Sharp & Dohme Corp. | Gamma secretase modulators |
| CN102209537A (zh) | 2008-11-10 | 2011-10-05 | 弗·哈夫曼-拉罗切有限公司 | 杂环γ分泌酶调节剂 |
| JP5503663B2 (ja) * | 2008-11-13 | 2014-05-28 | メルク・シャープ・アンド・ドーム・コーポレーション | ガンマセクレターゼモジュレータ |
| MX2011006782A (es) | 2009-02-26 | 2011-07-20 | Eisai R&D Man Co Ltd | Sal de derivado de tetrahidrotriazolopiridina y un cristal de la misma. |
| KR20110122746A (ko) | 2009-02-26 | 2011-11-10 | 에자이 알앤드디 매니지먼트 가부시키가이샤 | 질소를 함유하는 융합된 헤테로사이클릭 화합물 및 β 아밀로이드 생산 저해제로서의 용도 |
| JP2012176901A (ja) | 2009-09-25 | 2012-09-13 | Eisai R & D Management Co Ltd | 新規ベンゾニトリル化合物およびその製造方法 |
| US8486967B2 (en) | 2010-02-17 | 2013-07-16 | Hoffmann-La Roche Inc. | Heteroaryl substituted piperidines |
| US20130095068A1 (en) * | 2010-06-15 | 2013-04-18 | Eisai R&D Management Co., Ltd. | Agent for treating hcv infection |
| JP6095208B2 (ja) * | 2012-12-04 | 2017-03-15 | 学校法人慶應義塾 | 環化化合物の製造方法、及び、環化化合物を含有する溶液の発光方法 |
| WO2018107060A1 (en) * | 2016-12-09 | 2018-06-14 | Denali Therapeutics Inc. | Compounds, compositions and methods |
| AU2018269745C1 (en) | 2017-05-17 | 2022-06-09 | Denali Therapeutics Inc. | Compounds, compositions and methods |
| EP4041405A4 (en) * | 2019-10-07 | 2023-10-18 | D.E. Shaw Research, LLC | ARYLATED HETEROCYCLIC COMPOUNDS AS SHAKER KV1.3 POTASSIUM CHANNEL BLOCKERS |
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| NZ568050A (en) | 2005-11-24 | 2010-09-30 | Eisai R&D Man Co Ltd | Morpholine type cinnamide compound |
| WO2007102580A1 (ja) | 2006-03-09 | 2007-09-13 | Eisai R & D Management Co., Ltd. | 多環式シンナミド誘導体 |
| TWI378091B (en) | 2006-03-09 | 2012-12-01 | Eisai R&D Man Co Ltd | Multi-cyclic cinnamide derivatives |
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-
2006
- 2006-10-27 TW TW095139718A patent/TWI370130B/zh not_active IP Right Cessation
- 2006-11-01 EP EP06822806A patent/EP1953158B1/en active Active
- 2006-11-01 AU AU2006317468A patent/AU2006317468B2/en not_active Ceased
- 2006-11-01 GE GEAP200610709A patent/GEP20115172B/en unknown
- 2006-11-01 EA EA200801417A patent/EA014427B1/ru not_active IP Right Cessation
- 2006-11-01 NZ NZ568422A patent/NZ568422A/en not_active IP Right Cessation
- 2006-11-01 MY MYPI20081628A patent/MY144596A/en unknown
- 2006-11-01 WO PCT/JP2006/321877 patent/WO2007060821A1/ja active Application Filing
- 2006-11-01 BR BRPI0618890-7A patent/BRPI0618890A2/pt not_active IP Right Cessation
- 2006-11-01 ES ES06822806T patent/ES2394364T3/es active Active
- 2006-11-01 PL PL06822806T patent/PL1953158T3/pl unknown
- 2006-11-01 JP JP2007546389A patent/JP5178203B2/ja not_active Expired - Fee Related
- 2006-11-01 KR KR1020087014992A patent/KR101296239B1/ko not_active IP Right Cessation
- 2006-11-01 ME MEP-2008-49A patent/ME00040B/me unknown
- 2006-11-01 CA CA2629512A patent/CA2629512C/en not_active Expired - Fee Related
- 2006-11-01 RS RSP-2008/0242A patent/RS20080242A/xx unknown
- 2006-11-20 AR ARP060105075A patent/AR057915A1/es not_active Application Discontinuation
- 2006-11-21 PE PE2006001479A patent/PE20071029A1/es not_active Application Discontinuation
- 2006-11-22 SA SA6270432A patent/SA06270432B1/ar unknown
-
2008
- 2008-05-16 CR CR9983A patent/CR9983A/es not_active Application Discontinuation
- 2008-05-20 MA MA30952A patent/MA29968B1/fr unknown
- 2008-05-22 EC EC2008008466A patent/ECSP088466A/es unknown
- 2008-05-23 HN HN2008000792A patent/HN2008000792A/es unknown
- 2008-06-19 NO NO20082805A patent/NO20082805L/no not_active Application Discontinuation
- 2008-12-29 HK HK08114015.4A patent/HK1122806A1/xx not_active IP Right Cessation
-
2009
- 2009-03-13 US US12/403,565 patent/US8048878B2/en not_active Expired - Fee Related
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PC | Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee) |
Effective date: 20151101 |