HK1098762A1 - Il-18 binding proteins il-18 - Google Patents
Il-18 binding proteins il-18Info
- Publication number
- HK1098762A1 HK1098762A1 HK07101057.1A HK07101057A HK1098762A1 HK 1098762 A1 HK1098762 A1 HK 1098762A1 HK 07101057 A HK07101057 A HK 07101057A HK 1098762 A1 HK1098762 A1 HK 1098762A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- hil
- antibodies
- activity
- antibody
- binding proteins
- Prior art date
Links
- 102000044166 interleukin-18 binding protein Human genes 0.000 title abstract 2
- 108010070145 interleukin-18 binding protein Proteins 0.000 title abstract 2
- 101000960954 Homo sapiens Interleukin-18 Proteins 0.000 abstract 7
- 102000043959 human IL18 Human genes 0.000 abstract 7
- 230000000694 effects Effects 0.000 abstract 3
- 239000000427 antigen Substances 0.000 abstract 1
- 102000036639 antigens Human genes 0.000 abstract 1
- 108091007433 antigens Proteins 0.000 abstract 1
- 230000001627 detrimental effect Effects 0.000 abstract 1
- 238000000338 in vitro Methods 0.000 abstract 1
- 238000001727 in vivo Methods 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
Classifications
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6863—Cytokines, i.e. immune system proteins modifying a biological response such as cell growth proliferation or differentiation, e.g. TNF, CNF, GM-CSF, lymphotoxin, MIF or their receptors
- G01N33/6869—Interleukin
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
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- C07K2317/71—Decreased effector function due to an Fc-modification
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- C—CHEMISTRY; METALLURGY
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- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
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- C07K2317/94—Stability, e.g. half-life, pH, temperature or enzyme-resistance
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- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
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- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
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Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
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US10/706,689 US20050100965A1 (en) | 2003-11-12 | 2003-11-12 | IL-18 binding proteins |
PCT/US2004/037971 WO2005047307A2 (fr) | 2003-11-12 | 2004-11-12 | Proteines de liaison il-18 |
Publications (1)
Publication Number | Publication Date |
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HK1098762A1 true HK1098762A1 (en) | 2007-07-27 |
Family
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Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK07101057.1A HK1098762A1 (en) | 2003-11-12 | 2007-01-30 | Il-18 binding proteins il-18 |
Country Status (20)
Country | Link |
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US (1) | US20050100965A1 (fr) |
EP (5) | EP2460829A3 (fr) |
JP (4) | JP5054977B2 (fr) |
KR (4) | KR20060123148A (fr) |
CN (4) | CN1902229B (fr) |
AT (1) | ATE555130T1 (fr) |
AU (1) | AU2004290073B2 (fr) |
BR (1) | BRPI0416255A (fr) |
CA (2) | CA2543920A1 (fr) |
CY (1) | CY1112893T1 (fr) |
DK (1) | DK1685152T3 (fr) |
ES (1) | ES2385484T3 (fr) |
HK (1) | HK1098762A1 (fr) |
IL (2) | IL175422A0 (fr) |
NZ (2) | NZ593068A (fr) |
PL (1) | PL1685152T3 (fr) |
PT (1) | PT1685152E (fr) |
SI (1) | SI1685152T1 (fr) |
WO (1) | WO2005047307A2 (fr) |
ZA (1) | ZA200603733B (fr) |
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2003
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2004
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- 2004-11-12 EP EP11173615A patent/EP2460829A3/fr not_active Withdrawn
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- 2004-11-12 PL PL04817825T patent/PL1685152T3/pl unknown
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- 2004-11-12 CN CN2004800399482A patent/CN1902229B/zh not_active Expired - Fee Related
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- 2004-11-12 CA CA002543920A patent/CA2543920A1/fr not_active Abandoned
- 2004-11-12 KR KR1020127028781A patent/KR20120136416A/ko not_active Application Discontinuation
- 2004-11-12 DK DK04817825.5T patent/DK1685152T3/da active
- 2004-11-12 EP EP04817825A patent/EP1685152B1/fr not_active Not-in-force
- 2004-11-12 CN CN201010274020XA patent/CN101979412A/zh active Pending
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- 2004-11-12 EP EP11173650A patent/EP2395020A3/fr not_active Withdrawn
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- 2004-11-12 CA CA2805859A patent/CA2805859A1/fr not_active Abandoned
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- 2004-11-12 JP JP2006539948A patent/JP5054977B2/ja not_active Expired - Fee Related
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- 2004-11-12 AU AU2004290073A patent/AU2004290073B2/en not_active Ceased
- 2004-11-12 KR KR1020127031335A patent/KR20130006525A/ko not_active Application Discontinuation
- 2004-11-12 EP EP11173595A patent/EP2385070A1/fr not_active Withdrawn
- 2004-11-12 CN CN2012101293119A patent/CN102659944A/zh active Pending
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