HK10491A - 7-(pyrrol-1-yl)-1-ethyl-1,4-dihydro-4-oxoquinoline-3-carboxylic acid and 7-(pyrrol-1-yl)-1-ethyl-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acid derivatives, their preparation and use as medicaments - Google Patents

7-(pyrrol-1-yl)-1-ethyl-1,4-dihydro-4-oxoquinoline-3-carboxylic acid and 7-(pyrrol-1-yl)-1-ethyl-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acid derivatives, their preparation and use as medicaments Download PDF

Info

Publication number
HK10491A
HK10491A HK104/91A HK10491A HK10491A HK 10491 A HK10491 A HK 10491A HK 104/91 A HK104/91 A HK 104/91A HK 10491 A HK10491 A HK 10491A HK 10491 A HK10491 A HK 10491A
Authority
HK
Hong Kong
Prior art keywords
ethyl
dihydro
carboxylic acid
oxo
pyrrol
Prior art date
Application number
HK104/91A
Other languages
German (de)
English (en)
French (fr)
Inventor
Jose Esteve Soler
Original Assignee
Provesan S.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR8311250A external-priority patent/FR2548664B1/fr
Application filed by Provesan S.A. filed Critical Provesan S.A.
Publication of HK10491A publication Critical patent/HK10491A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
    • C07D215/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyrrole Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
HK104/91A 1983-07-06 1991-02-06 7-(pyrrol-1-yl)-1-ethyl-1,4-dihydro-4-oxoquinoline-3-carboxylic acid and 7-(pyrrol-1-yl)-1-ethyl-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acid derivatives, their preparation and use as medicaments HK10491A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8311250A FR2548664B1 (fr) 1983-07-06 1983-07-06 Derives 7-(pyrrol-l-yl) des acides l-ethyl-1,4-dihydro-4-oxoquinoleine-3-carboxyliques et l-ethyl-1,4-dihydro-4-oxo-(1,8-naphtyridine)-3-carboxyliques substitues, leur preparation et leur application en tant que medicaments
FR8402145A FR2559484B2 (fr) 1983-07-06 1984-02-13 Nouveau derive 7-(pyrrol-1-yl) de l'acide 1-ethyl-1,4-dihydro-4-oxo-(1,8-naphtyridin)-3-carboxylique, sa preparation et son application en tant que medicament

Publications (1)

Publication Number Publication Date
HK10491A true HK10491A (en) 1991-02-13

Family

ID=26223521

Family Applications (1)

Application Number Title Priority Date Filing Date
HK104/91A HK10491A (en) 1983-07-06 1991-02-06 7-(pyrrol-1-yl)-1-ethyl-1,4-dihydro-4-oxoquinoline-3-carboxylic acid and 7-(pyrrol-1-yl)-1-ethyl-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acid derivatives, their preparation and use as medicaments

Country Status (21)

Country Link
US (1) US4552882A (enExample)
EP (1) EP0134165B1 (enExample)
KR (1) KR880002355B1 (enExample)
AT (1) ATE34982T1 (enExample)
AU (1) AU564326B2 (enExample)
BR (1) BR8403342A (enExample)
CA (1) CA1256876A (enExample)
CS (1) CS244139B2 (enExample)
DD (1) DD223150A5 (enExample)
DE (1) DE3471934D1 (enExample)
DK (1) DK163126C (enExample)
ES (1) ES8503335A1 (enExample)
FR (1) FR2559484B2 (enExample)
GR (1) GR81646B (enExample)
HK (1) HK10491A (enExample)
HU (1) HU189916B (enExample)
MX (1) MX156436A (enExample)
NO (1) NO163329C (enExample)
PL (1) PL143730B1 (enExample)
PT (1) PT78854B (enExample)
YU (1) YU43577B (enExample)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2574404B1 (fr) * 1984-12-12 1987-04-24 Provesan Sa Derives 1-substitues de l'acide 6-fluoro-7-(pyrrol-1-yl)-1,4-dihydro-4-oxoquinoleine-3-carboxylique, leur preparation et leur application en tant que medicaments
DE3519286A1 (de) * 1985-05-30 1986-12-04 Bayer Ag, 5090 Leverkusen 7-azolyl-1-cyclopropyl-1,4-dihydro-4-oxo-3- chinolincarbonsaeuren und -1,8-naphthyridin-3-carbonsaeuren, verfahren zu ihrer herstellung sowie diese enthaltende antibakterielle mittel
US4692454A (en) * 1986-02-03 1987-09-08 Warner-Lambert Company Opthalmic use of quinolone antibiotics
DE3615767A1 (de) * 1986-05-10 1987-11-12 Bayer Ag Verfahren zur herstellung von 4-hydroxy-chinolin-3-carbonsaeuren
FR2607504B1 (fr) * 1986-12-02 1989-01-27 Rhone Poulenc Sante Nouveaux derives de l'isoindolinone, leur preparation et les compositions pharmaceutiques qui les contiennent
US5262417A (en) * 1988-12-06 1993-11-16 The Upjohn Company Antibacterial quinolone compounds
ES2051225B1 (es) * 1992-07-23 1994-12-16 Esteve Quimica Sa Procedimiento de preparacion del acido 1-etil-6-fluoro-7-(pirrol-1-il) -1,4-dihidro-4-oxo-3-quinoleincarboxilico.
EP1554572B1 (en) 2001-07-25 2009-10-14 Raptor Pharmaceutical Inc. Compositions and methods for modulating blood-brain barrier transport
DK1889198T3 (da) 2005-04-28 2015-02-09 Proteus Digital Health Inc Farma-informatiksystem
KR20090071598A (ko) 2006-09-18 2009-07-01 랩터 파마슈티컬 인코포레이티드 수용체 결합 단백질(ｒａｐ)-접합체 투여에 의한 간 질환의 치료
WO2010095940A2 (en) 2009-02-20 2010-08-26 To-Bbb Holding B.V. Glutathione-based drug delivery system
TWI556839B (zh) 2009-05-06 2016-11-11 研究室護膚股份有限公司 包含活性劑－磷酸鈣粒子複合物之皮膚遞送組成物及其使用方法
US20120077778A1 (en) 2010-09-29 2012-03-29 Andrea Bourdelais Ladder-Frame Polyether Conjugates
CN104803975A (zh) * 2015-04-24 2015-07-29 河南大学 一种氨甲基三唑取代的二氟喹诺酮羧酸类衍生物及其制备方法和应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2362553A1 (de) * 1972-12-18 1974-06-20 Dainippon Pharmaceutical Co Neue piperazinderivate
JPS5233694A (en) * 1975-09-09 1977-03-14 Dai Ichi Seiyaku Co Ltd Process for preparation of 6_nitro-1,8-naphthyridine derivatives
AR223983A1 (es) * 1978-08-25 1981-10-15 Dainippon Pharmaceutical Co Un procedimiento para-preparar derivados de acido 6-halogeno-4-oxo-7-(1-piperazinil)-1,8-naftiridin-3-carboxilico
JPS5649382A (en) * 1979-09-28 1981-05-02 Dainippon Pharmaceut Co Ltd 6-fluoro-7-cyclic amino-1,8-naphthylidine derivative and its salt

Also Published As

Publication number Publication date
DD223150A5 (de) 1985-06-05
ATE34982T1 (de) 1988-06-15
NO842717L (no) 1985-01-07
HUT34482A (en) 1985-03-28
ES533749A0 (es) 1985-03-01
US4552882A (en) 1985-11-12
PL248545A1 (en) 1985-07-16
EP0134165A3 (en) 1985-10-09
FR2559484A2 (fr) 1985-08-16
EP0134165A2 (fr) 1985-03-13
KR880002355B1 (ko) 1988-10-29
BR8403342A (pt) 1985-06-18
DK331384D0 (da) 1984-07-05
FR2559484B2 (fr) 1986-09-26
DK331384A (da) 1985-01-07
NO163329B (no) 1990-01-29
PL143730B1 (en) 1988-03-31
AU564326B2 (en) 1987-08-06
CA1256876A (en) 1989-07-04
PT78854A (fr) 1984-08-01
NO163329C (no) 1990-05-09
DK163126C (da) 1992-06-15
DK163126B (da) 1992-01-20
AU2942584A (en) 1985-01-10
EP0134165B1 (fr) 1988-06-08
MX156436A (es) 1988-08-22
GR81646B (enExample) 1984-12-11
KR850001198A (ko) 1985-03-16
HU189916B (en) 1986-08-28
YU43577B (en) 1989-08-31
CS244139B2 (en) 1986-07-17
PT78854B (fr) 1986-10-23
ES8503335A1 (es) 1985-03-01
YU119084A (en) 1986-12-31
CS528584A2 (en) 1985-08-31
DE3471934D1 (en) 1988-07-14

Similar Documents

Publication Publication Date Title
SU1598873A3 (ru) Способ получени производных хинолина или их фармацевтически приемлемых сложных эфиров или фармацевтически приемлемых аддитивных солей кислоты
JPH0314811B2 (enExample)
JPS6345261A (ja) 新規キノロン誘導体およびその塩
KR880002353B1 (ko) 퀴놀린 화합물 및 그의 제조방법
EP0009425A1 (en) Novel naphtyridine derivatives and pharmaceutical compositions containing them
HK10491A (en) 7-(pyrrol-1-yl)-1-ethyl-1,4-dihydro-4-oxoquinoline-3-carboxylic acid and 7-(pyrrol-1-yl)-1-ethyl-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acid derivatives, their preparation and use as medicaments
JPH0635457B2 (ja) ピリドンカルボン酸誘導体およびその製造方法
FI71144C (fi) Foerfarande foer framstaellning av terapeutiskt aktiv 1-etyl-6-fluor-1,4-dihydro-4-oxo-(1-piperazinyl)-1,8-naftyridin-3-karboxylsyraseskvihydrat
JPH01319463A (ja) ７―置換キノロン―及びナフチリドン―カルボン酸誘導体
US4496566A (en) Naphthyridine derivatives
EP0178388A1 (en) Quinolinecarboxylic acid derivatives
JPH0559914B2 (enExample)
JPS6339880A (ja) 新規な１，８−橋状結合された４−キノロンカルボン酸類およびこれらを含有している薬品類
JPH02290870A (ja) 対掌体的に純粋な７‐（３‐アミノ‐１‐ピロリジニル）‐キノロン‐および‐ナフチリドンカルボン酸
JPS6089480A (ja) ピリドンカルボン酸誘導体
KR930003611B1 (ko) 퀴놀론 카복실산 유도체의 제조방법
JPS6028978A (ja) １，８−ナフチリジン誘導体
JPH02191257A (ja) ベンゾヘテロ環化合物
DE3686201T2 (de) Benzo(i,j)chinolizin-2-carbonsaeurederivate, ihre salze und hydrate, diese enthaltende pharmazeutische zubereitungen und verfahren zu ihrer herstellung.
JPH026756B2 (enExample)
JPS58174367A (ja) キノリン誘導体及びその製法
JPH02243692A (ja) 三環式化合物
EP0221541A2 (en) Quinolonecarboxylic acid derivatives and their preparation
JPH0568477B2 (enExample)
US3324003A (en) Method of controlling growth of bacteria using 4-methyl-1-benzo[f]quinolone-2-carboxylic acid

Legal Events

Date Code Title Description
NR Patent deemed never to have been added to the register under section 13(7) of patents (transitional arrangements) rules