HK1047136A1 - 经扩增zwf基因发酵制备l-氨基酸的方法 - Google Patents

经扩增zwf基因发酵制备l-氨基酸的方法 Download PDF

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Publication number
HK1047136A1
HK1047136A1 HK02108775.2A HK02108775A HK1047136A1 HK 1047136 A1 HK1047136 A1 HK 1047136A1 HK 02108775 A HK02108775 A HK 02108775A HK 1047136 A1 HK1047136 A1 HK 1047136A1
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HK
Hong Kong
Prior art keywords
gene
ala
leu
gly
val
Prior art date
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HK02108775.2A
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English (en)
Chinese (zh)
Inventor
凯文‧伯克
凱文‧伯克
赫尔曼‧扎姆
洛塔尔‧埃格林
赫爾曼‧扎姆
贝恩德‧莫里茨
L‧K‧杜尼肯
洛塔爾‧埃格林
阿什令‧麦科麦克
克里奥娜‧斯特普尔顿
貝恩德‧莫里茨
贝蒂娜‧默克尔
格奥尔格‧蒂尔巴赫
阿什令‧麥科麥克
克里奧娜‧斯特普爾頓
貝蒂娜‧默克爾
格奧爾格‧蒂爾巴赫
Original Assignee
德古萨股份公司
于利希研究中心有限公司
国立爱尔兰大学
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Application filed by 德古萨股份公司, 于利希研究中心有限公司, 国立爱尔兰大学 filed Critical 德古萨股份公司
Publication of HK1047136A1 publication Critical patent/HK1047136A1/zh

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/08—Lysine; Diaminopimelic acid; Threonine; Valine

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
HK02108775.2A 2000-03-20 2000-07-05 经扩增zwf基因发酵制备l-氨基酸的方法 HK1047136A1 (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US53126900A 2000-03-20 2000-03-20
US09/531,269 2000-03-20
PCT/EP2000/006303 WO2001070995A1 (en) 2000-03-20 2000-07-05 Process for the fermentative preparation of l-amino acids with amplification of the zwf gene

Publications (1)

Publication Number Publication Date
HK1047136A1 true HK1047136A1 (zh) 2003-02-07

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Family Applications (1)

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HK02108775.2A HK1047136A1 (zh) 2000-03-20 2000-07-05 经扩增zwf基因发酵制备l-氨基酸的方法

Country Status (13)

Country Link
EP (1) EP1179073B1 (https=)
KR (1) KR100715641B1 (https=)
CN (2) CN1289676C (https=)
AT (1) ATE351908T1 (https=)
AU (1) AU6821900A (https=)
BR (1) BR0011283A (https=)
CA (1) CA2374261C (https=)
DE (2) DE60033026T4 (https=)
HK (1) HK1047136A1 (https=)
MX (1) MXPA01011644A (https=)
PL (1) PL205611B1 (https=)
SK (1) SK287997B6 (https=)
WO (1) WO2001070995A1 (https=)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6586214B1 (en) * 1999-09-15 2003-07-01 Degussa Ag Method for increasing the metabolic flux through the pentose phosphate cycle in coryneform bacteria by regulation of the phosphoglucose isomerase (pgi gene)
US6951729B1 (en) 1999-10-27 2005-10-04 Affinium Pharmaceuticals, Inc. High throughput screening method for biological agents affecting fatty acid biosynthesis
US6821746B2 (en) 2000-10-06 2004-11-23 Affinium Pharmaceuticals, Inc. Methods of screening for FabK antagonists and agonists
US7033795B2 (en) 2000-10-06 2006-04-25 Affinium Pharmaceuticals, Inc. FabK variant
US7048926B2 (en) 2000-10-06 2006-05-23 Affinium Pharmaceuticals, Inc. Methods of agonizing and antagonizing FabK
US7056697B2 (en) 2000-10-06 2006-06-06 Affinium Pharmaceuticals, Inc. FabK variant
DE10155505A1 (de) * 2001-11-13 2003-05-22 Basf Ag Gene die für Glucose-6-Phosphat-Dehydrogenase Proteine codieren
GB0208499D0 (en) * 2002-04-12 2002-05-22 Microscience Ltd Streptococcal genes
US7326546B2 (en) * 2005-03-10 2008-02-05 Ajinomoto Co., Inc. Purine-derived substance-producing bacterium and a method for producing purine-derived substance
DE102005013676A1 (de) 2005-03-24 2006-09-28 Degussa Ag Allele des zwf-Gens aus coryneformen Bakterien
US20070092951A1 (en) 2005-03-24 2007-04-26 Degussa Ag Alleles of the zwf gene from coryneform bacteria
CN104845923B (zh) * 2014-02-14 2018-03-23 中国科学院微生物研究所 生产l‑组氨酸的方法及其专用重组菌
CN106867952B (zh) * 2017-01-09 2019-10-18 天津科技大学 一株大肠杆菌基因工程菌及利用其生产l-苏氨酸的方法
CN107267568A (zh) * 2017-07-21 2017-10-20 徐州工程学院 利用spoT基因缺失菌株通过发酵生产L‑氨基酸的方法
CN109423504B (zh) * 2017-08-24 2022-10-04 廊坊梅花生物技术开发有限公司 生产l-色氨酸的菌株及用途
CN116606786A (zh) * 2022-02-08 2023-08-18 廊坊梅花生物技术开发有限公司 一种生产苏氨酸的重组微生物及其构建方法和应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH09224661A (ja) 1996-02-23 1997-09-02 Mitsubishi Chem Corp グルコース−６−リン酸デヒドロゲナーゼおよびそれをコードするｄｎａ
EP1257649B1 (en) * 1999-06-25 2010-01-20 Paik Kwang Industrial Co., Ltd. Corynebacterium glutamicum genes encoding metabolic pathway proteins
JP4623825B2 (ja) * 1999-12-16 2011-02-02 協和発酵バイオ株式会社 新規ポリヌクレオチド

Also Published As

Publication number Publication date
EP1179073A1 (en) 2002-02-13
DE60033026T2 (de) 2007-11-15
CN1289676C (zh) 2006-12-13
AU6821900A (en) 2001-10-03
CN101029310A (zh) 2007-09-05
KR20020012578A (ko) 2002-02-16
EP1179073B1 (en) 2007-01-17
CA2374261C (en) 2010-04-20
CN1353758A (zh) 2002-06-12
ATE351908T1 (de) 2007-02-15
SK16532001A3 (sk) 2002-07-02
PL205611B1 (pl) 2010-05-31
CN101029310B (zh) 2010-12-08
WO2001070995A1 (en) 2001-09-27
DE60033026D1 (de) 2007-03-08
MX244419B (https=) 2007-03-26
KR100715641B1 (ko) 2007-05-08
CA2374261A1 (en) 2001-09-27
MXPA01011644A (es) 2003-02-27
BR0011283A (pt) 2002-03-05
DE60033026T4 (de) 2015-09-10
PL358914A1 (en) 2004-08-23
SK287997B6 (sk) 2012-09-03

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