HK1045682B - 制备-2-(n-苯基氨基)苯甲酸衍生物的方法 - Google Patents

制备-2-(n-苯基氨基)苯甲酸衍生物的方法 Download PDF

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Publication number
HK1045682B
HK1045682B HK02107069.9A HK02107069A HK1045682B HK 1045682 B HK1045682 B HK 1045682B HK 02107069 A HK02107069 A HK 02107069A HK 1045682 B HK1045682 B HK 1045682B
Authority
HK
Hong Kong
Prior art keywords
benzoic acid
formula
phenylamino
aniline
alkali metal
Prior art date
Application number
HK02107069.9A
Other languages
English (en)
Chinese (zh)
Other versions
HK1045682A1 (en
Inventor
M‧H‧G‧臣
J‧玛噶诺
J‧瑪噶諾
Original Assignee
沃尼尔‧朗伯公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 沃尼尔‧朗伯公司 filed Critical 沃尼尔‧朗伯公司
Publication of HK1045682A1 publication Critical patent/HK1045682A1/xx
Publication of HK1045682B publication Critical patent/HK1045682B/zh

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C227/04—Formation of amino groups in compounds containing carboxyl groups
    • C07C227/06—Formation of amino groups in compounds containing carboxyl groups by addition or substitution reactions, without increasing the number of carbon atoms in the carbon skeleton of the acid
    • C07C227/08—Formation of amino groups in compounds containing carboxyl groups by addition or substitution reactions, without increasing the number of carbon atoms in the carbon skeleton of the acid by reaction of ammonia or amines with acids containing functional groups

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
HK02107069.9A 1999-04-21 2000-02-16 制备-2-(n-苯基氨基)苯甲酸衍生物的方法 HK1045682B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US13038499P 1999-04-21 1999-04-21
US60/130,384 1999-04-21
PCT/US2000/003982 WO2000064856A1 (en) 1999-04-21 2000-02-16 Method for making 2-(n-phenylamino)benzoic acids

Publications (2)

Publication Number Publication Date
HK1045682A1 HK1045682A1 (en) 2002-12-06
HK1045682B true HK1045682B (zh) 2006-04-07

Family

ID=22444462

Family Applications (1)

Application Number Title Priority Date Filing Date
HK02107069.9A HK1045682B (zh) 1999-04-21 2000-02-16 制备-2-(n-苯基氨基)苯甲酸衍生物的方法

Country Status (34)

Country Link
EP (1) EP1171418B1 (https=)
JP (1) JP3769192B2 (https=)
KR (1) KR20010108521A (https=)
CN (1) CN1213997C (https=)
AP (1) AP2001002328A0 (https=)
AT (1) ATE286015T1 (https=)
AU (1) AU773096B2 (https=)
BG (1) BG106132A (https=)
BR (1) BR0009886A (https=)
CA (1) CA2368807A1 (https=)
CR (1) CR6486A (https=)
CU (1) CU22996A3 (https=)
DE (1) DE60017109T2 (https=)
DK (1) DK1171418T3 (https=)
EA (1) EA004209B1 (https=)
EE (1) EE200100546A (https=)
ES (1) ES2235843T3 (https=)
GE (1) GEP20033089B (https=)
HK (1) HK1045682B (https=)
HR (1) HRP20010850A2 (https=)
HU (1) HUP0200932A3 (https=)
IL (1) IL146056A0 (https=)
MA (1) MA25412A1 (https=)
NO (1) NO20015095D0 (https=)
NZ (1) NZ515120A (https=)
OA (1) OA11861A (https=)
PL (1) PL351085A1 (https=)
PT (1) PT1171418E (https=)
SK (1) SK14732001A3 (https=)
TR (1) TR200103015T2 (https=)
UA (1) UA70995C2 (https=)
WO (1) WO2000064856A1 (https=)
YU (1) YU73701A (https=)
ZA (1) ZA200107834B (https=)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SK2072003A3 (en) * 2000-08-25 2004-01-08 Warner Lambert Co Process for making N-aryl-anthranilic acids and their derivatives
ES2346998T3 (es) * 2005-04-06 2010-10-22 Chugai Seiyaku Kabushiki Kaisha Procedimiento para la produccion de acido 2,3,4-trifluoro-5-(yodo o bromo)benzoico.
JPWO2007021001A1 (ja) * 2005-08-18 2009-02-26 宇部興産株式会社 ２，３，４−トリフルオロ−５−置換安息香酸化合物及びその製法
CN102985399A (zh) * 2010-02-19 2013-03-20 国家科学研究中心 通过对携带至少一个吸电子基团的芳香族羧酸衍生物进行亲核芳香族取代来制备目的化合物的方法
JP2013519714A (ja) * 2010-02-19 2013-05-30 センター ナショナル デ ラ リシェルシェ サイエンティフィック 芳香族求核置換によって目的の化学化合物を調製するための方法
JP2016034900A (ja) * 2012-11-26 2016-03-17 中外製薬株式会社 ５−置換−２−フェニルアミノ−ベンズアミド類の製造方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ501276A (en) * 1997-07-01 2000-10-27 Warner Lambert Co 4-bromo or 4-iodo phenylamino benzhydroxamic acid derivatives and their use as MEK inhibitors in treating proliferative disorders

Also Published As

Publication number Publication date
DK1171418T3 (da) 2005-05-09
UA70995C2 (uk) 2004-11-15
AU773096B2 (en) 2004-05-13
HRP20010850A2 (en) 2002-12-31
SK14732001A3 (sk) 2002-05-09
IL146056A0 (en) 2002-07-25
JP2002543055A (ja) 2002-12-17
EA004209B1 (ru) 2004-02-26
WO2000064856A1 (en) 2000-11-02
HK1045682A1 (en) 2002-12-06
YU73701A (sh) 2005-06-10
CR6486A (es) 2004-03-11
CU22996A3 (es) 2004-10-12
AP2001002328A0 (en) 2001-12-31
KR20010108521A (ko) 2001-12-07
CN1347403A (zh) 2002-05-01
EA200101113A1 (ru) 2002-04-25
JP3769192B2 (ja) 2006-04-19
NZ515120A (en) 2003-08-29
EP1171418A1 (en) 2002-01-16
AU3492800A (en) 2000-11-10
BG106132A (en) 2002-06-28
ES2235843T3 (es) 2005-07-16
DE60017109T2 (de) 2006-01-12
ATE286015T1 (de) 2005-01-15
CA2368807A1 (en) 2000-11-02
HUP0200932A3 (en) 2002-11-28
MA25412A1 (fr) 2002-04-01
PT1171418E (pt) 2005-02-28
GEP20033089B (en) 2003-10-27
OA11861A (en) 2006-03-02
PL351085A1 (en) 2003-03-24
TR200103015T2 (tr) 2002-01-21
NO20015095L (no) 2001-10-19
CN1213997C (zh) 2005-08-10
BR0009886A (pt) 2002-01-22
EE200100546A (et) 2003-02-17
HUP0200932A2 (hu) 2002-07-29
ZA200107834B (en) 2002-12-23
NO20015095D0 (no) 2001-10-19
DE60017109D1 (de) 2005-02-03
EP1171418B1 (en) 2004-12-29

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Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20100216