BR0009886A - Método para a fabricação de ácidos 2-(n-fenilamino) benzóicos - Google Patents
Método para a fabricação de ácidos 2-(n-fenilamino) benzóicosInfo
- Publication number
- BR0009886A BR0009886A BR0009886-8A BR0009886A BR0009886A BR 0009886 A BR0009886 A BR 0009886A BR 0009886 A BR0009886 A BR 0009886A BR 0009886 A BR0009886 A BR 0009886A
- Authority
- BR
- Brazil
- Prior art keywords
- manufacture
- phenylamino
- benzoic acids
- benzoic
- acids
- Prior art date
Links
- 238000004519 manufacturing process Methods 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 3
- 235000010233 benzoic acid Nutrition 0.000 title abstract 2
- 150000001559 benzoic acids Chemical class 0.000 title abstract 2
- PAYRUJLWNCNPSJ-UHFFFAOYSA-N N-phenyl amine Natural products NC1=CC=CC=C1 PAYRUJLWNCNPSJ-UHFFFAOYSA-N 0.000 abstract 4
- WPYMKLBDIGXBTP-UHFFFAOYSA-N benzoic acid Chemical compound OC(=O)C1=CC=CC=C1 WPYMKLBDIGXBTP-UHFFFAOYSA-N 0.000 abstract 2
- 239000005711 Benzoic acid Substances 0.000 abstract 1
- 229910052783 alkali metal Inorganic materials 0.000 abstract 1
- -1 alkali metal hexamethyldisilazide Chemical class 0.000 abstract 1
- 239000002585 base Substances 0.000 abstract 1
- 230000008878 coupling Effects 0.000 abstract 1
- 238000010168 coupling process Methods 0.000 abstract 1
- 238000005859 coupling reaction Methods 0.000 abstract 1
- ZWJINEZUASEZBH-UHFFFAOYSA-N fenamic acid Chemical class OC(=O)C1=CC=CC=C1NC1=CC=CC=C1 ZWJINEZUASEZBH-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C227/04—Formation of amino groups in compounds containing carboxyl groups
- C07C227/06—Formation of amino groups in compounds containing carboxyl groups by addition or substitution reactions, without increasing the number of carbon atoms in the carbon skeleton of the acid
- C07C227/08—Formation of amino groups in compounds containing carboxyl groups by addition or substitution reactions, without increasing the number of carbon atoms in the carbon skeleton of the acid by reaction of ammonia or amines with acids containing functional groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US13038499P | 1999-04-21 | 1999-04-21 | |
| PCT/US2000/003982 WO2000064856A1 (en) | 1999-04-21 | 2000-02-16 | Method for making 2-(n-phenylamino)benzoic acids |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR0009886A true BR0009886A (pt) | 2002-01-22 |
Family
ID=22444462
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR0009886-8A BR0009886A (pt) | 1999-04-21 | 2000-02-16 | Método para a fabricação de ácidos 2-(n-fenilamino) benzóicos |
Country Status (34)
| Country | Link |
|---|---|
| EP (1) | EP1171418B1 (https=) |
| JP (1) | JP3769192B2 (https=) |
| KR (1) | KR20010108521A (https=) |
| CN (1) | CN1213997C (https=) |
| AP (1) | AP2001002328A0 (https=) |
| AT (1) | ATE286015T1 (https=) |
| AU (1) | AU773096B2 (https=) |
| BG (1) | BG106132A (https=) |
| BR (1) | BR0009886A (https=) |
| CA (1) | CA2368807A1 (https=) |
| CR (1) | CR6486A (https=) |
| CU (1) | CU22996A3 (https=) |
| DE (1) | DE60017109T2 (https=) |
| DK (1) | DK1171418T3 (https=) |
| EA (1) | EA004209B1 (https=) |
| EE (1) | EE200100546A (https=) |
| ES (1) | ES2235843T3 (https=) |
| GE (1) | GEP20033089B (https=) |
| HK (1) | HK1045682B (https=) |
| HR (1) | HRP20010850A2 (https=) |
| HU (1) | HUP0200932A3 (https=) |
| IL (1) | IL146056A0 (https=) |
| MA (1) | MA25412A1 (https=) |
| NO (1) | NO20015095D0 (https=) |
| NZ (1) | NZ515120A (https=) |
| OA (1) | OA11861A (https=) |
| PL (1) | PL351085A1 (https=) |
| PT (1) | PT1171418E (https=) |
| SK (1) | SK14732001A3 (https=) |
| TR (1) | TR200103015T2 (https=) |
| UA (1) | UA70995C2 (https=) |
| WO (1) | WO2000064856A1 (https=) |
| YU (1) | YU73701A (https=) |
| ZA (1) | ZA200107834B (https=) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SK2072003A3 (en) * | 2000-08-25 | 2004-01-08 | Warner Lambert Co | Process for making N-aryl-anthranilic acids and their derivatives |
| ES2346998T3 (es) * | 2005-04-06 | 2010-10-22 | Chugai Seiyaku Kabushiki Kaisha | Procedimiento para la produccion de acido 2,3,4-trifluoro-5-(yodo o bromo)benzoico. |
| JPWO2007021001A1 (ja) * | 2005-08-18 | 2009-02-26 | 宇部興産株式会社 | ２，３，４−トリフルオロ−５−置換安息香酸化合物及びその製法 |
| CN102985399A (zh) * | 2010-02-19 | 2013-03-20 | 国家科学研究中心 | 通过对携带至少一个吸电子基团的芳香族羧酸衍生物进行亲核芳香族取代来制备目的化合物的方法 |
| JP2013519714A (ja) * | 2010-02-19 | 2013-05-30 | センター ナショナル デ ラ リシェルシェ サイエンティフィック | 芳香族求核置換によって目的の化学化合物を調製するための方法 |
| JP2016034900A (ja) * | 2012-11-26 | 2016-03-17 | 中外製薬株式会社 | ５−置換−２−フェニルアミノ−ベンズアミド類の製造方法 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ501276A (en) * | 1997-07-01 | 2000-10-27 | Warner Lambert Co | 4-bromo or 4-iodo phenylamino benzhydroxamic acid derivatives and their use as MEK inhibitors in treating proliferative disorders |
-
2000
- 2000-02-16 PT PT00913489T patent/PT1171418E/pt unknown
- 2000-02-16 AU AU34928/00A patent/AU773096B2/en not_active Ceased
- 2000-02-16 HU HU0200932A patent/HUP0200932A3/hu unknown
- 2000-02-16 CN CNB008064423A patent/CN1213997C/zh not_active Expired - Fee Related
- 2000-02-16 KR KR1020017013402A patent/KR20010108521A/ko not_active Ceased
- 2000-02-16 NZ NZ515120A patent/NZ515120A/en unknown
- 2000-02-16 PL PL00351085A patent/PL351085A1/xx not_active IP Right Cessation
- 2000-02-16 GE GEAP20006152A patent/GEP20033089B/en unknown
- 2000-02-16 OA OA1200100260A patent/OA11861A/en unknown
- 2000-02-16 AP APAP/P/2001/002328A patent/AP2001002328A0/en unknown
- 2000-02-16 HK HK02107069.9A patent/HK1045682B/zh not_active IP Right Cessation
- 2000-02-16 BR BR0009886-8A patent/BR0009886A/pt not_active IP Right Cessation
- 2000-02-16 DK DK00913489T patent/DK1171418T3/da active
- 2000-02-16 EP EP00913489A patent/EP1171418B1/en not_active Expired - Lifetime
- 2000-02-16 IL IL14605600A patent/IL146056A0/xx unknown
- 2000-02-16 TR TR2001/03015T patent/TR200103015T2/xx unknown
- 2000-02-16 JP JP2000613809A patent/JP3769192B2/ja not_active Expired - Fee Related
- 2000-02-16 EE EEP200100546A patent/EE200100546A/xx unknown
- 2000-02-16 ES ES00913489T patent/ES2235843T3/es not_active Expired - Lifetime
- 2000-02-16 SK SK1473-2001A patent/SK14732001A3/sk unknown
- 2000-02-16 HR HR20010850A patent/HRP20010850A2/hr not_active Application Discontinuation
- 2000-02-16 UA UA2001096639A patent/UA70995C2/uk unknown
- 2000-02-16 CA CA002368807A patent/CA2368807A1/en not_active Abandoned
- 2000-02-16 AT AT00913489T patent/ATE286015T1/de not_active IP Right Cessation
- 2000-02-16 WO PCT/US2000/003982 patent/WO2000064856A1/en not_active Ceased
- 2000-02-16 DE DE60017109T patent/DE60017109T2/de not_active Expired - Fee Related
- 2000-02-16 EA EA200101113A patent/EA004209B1/ru not_active IP Right Cessation
- 2000-02-16 YU YU73701A patent/YU73701A/sh unknown
-
2001
- 2001-09-21 ZA ZA200107834A patent/ZA200107834B/en unknown
- 2001-09-21 CU CU20010213A patent/CU22996A3/es unknown
- 2001-10-19 CR CR6486A patent/CR6486A/es not_active Application Discontinuation
- 2001-10-19 NO NO20015095A patent/NO20015095D0/no not_active Application Discontinuation
- 2001-11-16 MA MA26413A patent/MA25412A1/fr unknown
- 2001-11-21 BG BG106132A patent/BG106132A/xx unknown
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 8A E 9A ANUIDADES. |
|
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 NA RPI2003 DE 26/05/2009. |