BRPI0517065A - derivado de ácido carboxìlico que contém anel de tiazol e uso farmacêutico deste - Google Patents

derivado de ácido carboxìlico que contém anel de tiazol e uso farmacêutico deste

Info

Publication number
BRPI0517065A
BRPI0517065A BRPI0517065-6A BRPI0517065A BRPI0517065A BR PI0517065 A BRPI0517065 A BR PI0517065A BR PI0517065 A BRPI0517065 A BR PI0517065A BR PI0517065 A BRPI0517065 A BR PI0517065A
Authority
BR
Brazil
Prior art keywords
carboxylic acid
acid derivative
pharmaceutical use
containing carboxylic
thiazole ring
Prior art date
Application number
BRPI0517065-6A
Other languages
English (en)
Inventor
Takashi Tozawa
Osamu Tsuruta
Hiroshi Katajima
Yoshiyuki Aoki
Naoko Ando
Hiroki Tamakawa
Original Assignee
Mitsubishi Pharma Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mitsubishi Pharma Corp filed Critical Mitsubishi Pharma Corp
Publication of BRPI0517065A publication Critical patent/BRPI0517065A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/36—Sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/426—1,3-Thiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Abstract

DERIVADO DE áCIDO CARBOXìLICO QUE CONTéM ANEL DE TIAZOL E USO FARMACêUTICO DESTE. De acordo com a presente invenção, um composto representado pela seguinte fórmula (1) tendo um ação agonista de PPAR<244> superior e concomitantemente mostrando uma ação hipolipidêmica pode ser fornecida, e além disso, um composto útil como um intermediário sintéticos para o composto pode ser fornecido.
BRPI0517065-6A 2004-11-04 2005-11-04 derivado de ácido carboxìlico que contém anel de tiazol e uso farmacêutico deste BRPI0517065A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2004321347 2004-11-04
PCT/JP2005/020262 WO2006049232A1 (ja) 2004-11-04 2005-11-04 チアゾール環を含むカルボン酸誘導体およびその医薬用途

Publications (1)

Publication Number Publication Date
BRPI0517065A true BRPI0517065A (pt) 2008-09-30

Family

ID=36319233

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0517065-6A BRPI0517065A (pt) 2004-11-04 2005-11-04 derivado de ácido carboxìlico que contém anel de tiazol e uso farmacêutico deste

Country Status (10)

Country Link
US (1) US8026370B2 (pt)
EP (1) EP1816128A4 (pt)
JP (1) JP4939226B2 (pt)
KR (1) KR100918523B1 (pt)
CN (1) CN101068797A (pt)
AU (1) AU2005301626B2 (pt)
BR (1) BRPI0517065A (pt)
CA (1) CA2587023C (pt)
TW (1) TWI359810B (pt)
WO (1) WO2006049232A1 (pt)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW200533357A (en) 2004-01-08 2005-10-16 Millennium Pharm Inc 2-(amino-substituted)-4-aryl pyrimidines and related compounds useful for treating inflammatory diseases
WO2007126043A1 (ja) * 2006-04-27 2007-11-08 Mitsubishi Tanabe Pharma Corporation チアゾール環を含むカルボン酸誘導体の医薬用途
US20090264433A1 (en) * 2008-04-21 2009-10-22 Institute For Oneworld Health Compounds, Compositions and Methods Comprising Triazine Derivatives
US8207205B2 (en) 2008-04-21 2012-06-26 Institute For Oneworld Health Compounds, compositions and methods comprising oxadiazole derivatives
WO2009131951A2 (en) * 2008-04-21 2009-10-29 Institute For Oneworld Health Compounds, compositions and methods comprising isoxazole derivatives
WO2009131947A2 (en) * 2008-04-21 2009-10-29 Institute For Oneworld Health Compounds, compositions and methods comprising pyridazine derivatives
WO2010033626A1 (en) * 2008-09-19 2010-03-25 Institute For Oneworld Health Compounds, compositions and methods comprising imidazole and triazole derivatives
US8497382B2 (en) 2008-12-01 2013-07-30 Mitsubishi Tanabe Pharma Corporation Carboxylic acid derivative containing thiazole ring and pharmaceutical use thereof
US8511216B2 (en) * 2009-03-30 2013-08-20 Kanzaki Kokyukoki Mfg. Co., Ltd. Hydraulic actuator unit
US8343976B2 (en) * 2009-04-20 2013-01-01 Institute For Oneworld Health Compounds, compositions and methods comprising pyrazole derivatives
WO2011037223A1 (ja) 2009-09-28 2011-03-31 興和株式会社 内臓脂肪重量の低下剤
EP2804605A4 (en) 2012-01-20 2015-07-08 Acucela Inc SUBSTITUTED HETEROCYCLIC COMPOUNDS FOR THE TREATMENT OF DISEASES
AU2013321918B2 (en) 2012-09-27 2018-05-10 Kowa Company, Ltd. Therapeutic agent for dyslipidemia
WO2015030033A1 (ja) 2013-08-28 2015-03-05 興和株式会社 脂質異常症治療剤
US11799737B1 (en) * 2021-06-30 2023-10-24 Juniper Networks, Inc. Topology-based graphical user interface for network management systems

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3508665A1 (de) * 1985-03-12 1986-09-18 Hoechst Ag, 6230 Frankfurt Heterocyclische sulfide und ihre anwendung als immunmodulatoren
JPS62212590A (ja) * 1986-03-14 1987-09-18 Matsushita Electric Ind Co Ltd 路面凍結警告装置
CA2044755A1 (en) * 1990-06-18 1991-12-19 Bunji Natsume Pyrazolecarboxamide, insecticidal and miticidal composition, and fungicidal composition for use in agriculture and horticulture
ZA9610046B (en) 1995-12-01 1997-07-10 Ciba Geigy Process for preparing 2-chlorothiazole compounds
CZ296558B6 (cs) 1996-12-19 2006-04-12 Syngenta Participations Ag Zpusob prípravy derivátu thiazolu a meziprodukt tohoto zpusobu
ES2246985T3 (es) * 1996-12-19 2006-03-01 Syngenta Participations Ag Preparacion de tiazoles.
EP1026149A4 (en) * 1997-10-02 2004-12-01 Sankyo Co AMIDOCARBONSÄUREDERIVATE
EP1394154A4 (en) 2001-03-23 2005-05-18 Takeda Pharmaceutical HETEROCYCLIC DERIVATIVE WITH FIVE MEMBERS OF ALKANOIC ACID
PL367676A1 (en) * 2001-05-29 2005-03-07 Kyoto Pharmaceutical Industries, Ltd. Novel heterocyclic derivatives and medicinal use thereof
CZ20033450A3 (cs) * 2001-05-29 2004-05-12 Kyotoápharmaceuticaláindustriesźáltd Heterocyklická sloučenina a její lékařské použití
US20070166227A1 (en) 2004-02-10 2007-07-19 Shuang Liu Crowned dithiocarbamate metal complexes and methods for their use
GB0403148D0 (en) * 2004-02-12 2004-03-17 Smithkline Beecham Corp Chemical compounds
JPWO2007020829A1 (ja) * 2005-08-12 2009-02-26 株式会社島精機製作所 パイピング部を有する編地の編成方法およびその編地

Also Published As

Publication number Publication date
JPWO2006049232A1 (ja) 2008-05-29
WO2006049232A1 (ja) 2006-05-11
TWI359810B (en) 2012-03-11
AU2005301626A1 (en) 2006-05-11
EP1816128A4 (en) 2009-11-18
CN101068797A (zh) 2007-11-07
TW200626564A (en) 2006-08-01
AU2005301626B2 (en) 2011-11-17
CA2587023A1 (en) 2006-05-11
KR100918523B1 (ko) 2009-09-21
CA2587023C (en) 2011-11-01
EP1816128A1 (en) 2007-08-08
JP4939226B2 (ja) 2012-05-23
US8026370B2 (en) 2011-09-27
KR20070085687A (ko) 2007-08-27
US20080167307A1 (en) 2008-07-10

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Legal Events

Date Code Title Description
B25A Requested transfer of rights approved

Owner name: TANABE SEIYAKU CO., LTD. (JP)

Free format text: TRANSFERIDO POR FUSAO DE: MITSUBISHI PHARMA CORPORATION

B25D Requested change of name of applicant approved

Owner name: MITSUBISHI TANABE PHARMA CORPORATION (JP)

Free format text: ALTERADO DE: TANABE SEIYAKU CO., LTD.

B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 10A ANUIDADE.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2330 DE 01-09-2015 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.