HK1043158A1 - 基於質譜的dna診斷 - Google Patents
基於質譜的dna診斷Info
- Publication number
- HK1043158A1 HK1043158A1 HK02103765.5A HK02103765A HK1043158A1 HK 1043158 A1 HK1043158 A1 HK 1043158A1 HK 02103765 A HK02103765 A HK 02103765A HK 1043158 A1 HK1043158 A1 HK 1043158A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- branching
- well
- sub
- outlet
- branch
- Prior art date
Links
- 238000004949 mass spectrometry Methods 0.000 title abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 208000031404 Chromosome Aberrations Diseases 0.000 abstract 1
- 208000026350 Inborn Genetic disease Diseases 0.000 abstract 1
- 108091028043 Nucleic acid sequence Proteins 0.000 abstract 1
- 239000012472 biological sample Substances 0.000 abstract 1
- 239000004568 cement Substances 0.000 abstract 1
- 238000010276 construction Methods 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 208000016361 genetic disease Diseases 0.000 abstract 1
- 208000015181 infectious disease Diseases 0.000 abstract 1
- 150000007523 nucleic acids Chemical group 0.000 abstract 1
- 244000052769 pathogen Species 0.000 abstract 1
Classifications
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- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
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- C07F9/24—Esteramides
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- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/11—Compounds covalently bound to a solid support
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- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B40/00—Libraries per se, e.g. arrays, mixtures
- C40B40/04—Libraries containing only organic compounds
- C40B40/06—Libraries containing nucleotides or polynucleotides, or derivatives thereof
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- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B40/00—Libraries per se, e.g. arrays, mixtures
- C40B40/04—Libraries containing only organic compounds
- C40B40/10—Libraries containing peptides or polypeptides, or derivatives thereof
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- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B60/00—Apparatus specially adapted for use in combinatorial chemistry or with libraries
- C40B60/14—Apparatus specially adapted for use in combinatorial chemistry or with libraries for creating libraries
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N2035/00178—Special arrangements of analysers
- G01N2035/00237—Handling microquantities of analyte, e.g. microvalves, capillary networks
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
- G01N2035/1027—General features of the devices
- G01N2035/1034—Transferring microquantities of liquid
- G01N2035/1037—Using surface tension, e.g. pins or wires
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
- G01N35/1065—Multiple transfer devices
- G01N35/1067—Multiple transfer devices for transfer to or from containers having different spacing
- G01N2035/1069—Multiple transfer devices for transfer to or from containers having different spacing by adjusting the spacing between multiple probes of a single transferring head
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
- G01N35/1065—Multiple transfer devices
- G01N35/1074—Multiple transfer devices arranged in a two-dimensional array
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- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
- H01J49/00—Particle spectrometers or separator tubes
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- Chemical & Material Sciences (AREA)
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- Proteomics, Peptides & Aminoacids (AREA)
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- Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
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US74605596A | 1996-11-06 | 1996-11-06 | |
US08/746,036 US5900481A (en) | 1996-11-06 | 1996-11-06 | Bead linkers for immobilizing nucleic acids to solid supports |
US08/744,481 US6428955B1 (en) | 1995-03-17 | 1996-11-06 | DNA diagnostics based on mass spectrometry |
US08/744,590 US6074823A (en) | 1993-03-19 | 1996-11-06 | DNA sequencing by mass spectrometry via exonuclease degradation |
US08/787,639 US6024925A (en) | 1997-01-23 | 1997-01-23 | Systems and methods for preparing low volume analyte array elements |
US08/786,988 US7285422B1 (en) | 1997-01-23 | 1997-01-23 | Systems and methods for preparing and analyzing low volume analyte array elements |
US08/933,792 US6133436A (en) | 1996-11-06 | 1997-09-19 | Beads bound to a solid support and to nucleic acids |
US94780197A | 1997-10-08 | 1997-10-08 |
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HK02103765.5A HK1043158A1 (zh) | 1996-11-06 | 2002-05-18 | 基於質譜的dna診斷 |
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EP (2) | EP0954612A2 (zh) |
AT (1) | ATE375403T1 (zh) |
AU (1) | AU735416B2 (zh) |
CA (1) | CA2270132A1 (zh) |
DE (2) | DE69738206T2 (zh) |
HK (1) | HK1043158A1 (zh) |
NO (1) | NO992168L (zh) |
WO (1) | WO1998020166A2 (zh) |
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- 1997-11-06 CA CA002270132A patent/CA2270132A1/en not_active Abandoned
- 1997-11-06 WO PCT/US1997/020444 patent/WO1998020166A2/en not_active Application Discontinuation
- 1997-11-06 US US09/297,576 patent/US20030129589A1/en not_active Abandoned
- 1997-11-06 EP EP97945641A patent/EP0954612A2/en not_active Withdrawn
- 1997-11-06 DE DE19782095T patent/DE19782095T1/de not_active Ceased
- 1997-11-06 AU AU51069/98A patent/AU735416B2/en not_active Ceased
- 1997-11-06 AT AT01203019T patent/ATE375403T1/de not_active IP Right Cessation
- 1997-11-06 EP EP01203019A patent/EP1164203B1/en not_active Expired - Lifetime
-
1998
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-
1999
- 1999-05-04 NO NO992168A patent/NO992168L/no not_active Application Discontinuation
-
2000
- 2000-10-10 US US09/686,148 patent/US7198893B1/en not_active Expired - Fee Related
-
2002
- 2002-05-18 HK HK02103765.5A patent/HK1043158A1/zh unknown
-
2006
- 2006-10-02 US US11/541,871 patent/US7501251B2/en not_active Expired - Fee Related
-
2008
- 2008-06-27 US US12/163,923 patent/US20090023150A1/en not_active Abandoned
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Publication number | Publication date |
---|---|
DE19782095T1 (de) | 2000-03-23 |
ATE375403T1 (de) | 2007-10-15 |
DE69738206T2 (de) | 2008-07-17 |
WO1998020166A2 (en) | 1998-05-14 |
EP1164203A2 (en) | 2001-12-19 |
EP1164203B1 (en) | 2007-10-10 |
AU5106998A (en) | 1998-05-29 |
NO992168D0 (no) | 1999-05-04 |
EP0954612A2 (en) | 1999-11-10 |
NO992168L (no) | 1999-07-06 |
WO1998020166A3 (en) | 1998-10-22 |
US20090023150A1 (en) | 2009-01-22 |
US20070202514A1 (en) | 2007-08-30 |
US20020042112A1 (en) | 2002-04-11 |
US7501251B2 (en) | 2009-03-10 |
EP1164203A3 (en) | 2002-03-13 |
CA2270132A1 (en) | 1998-05-14 |
AU735416B2 (en) | 2001-07-05 |
US20030129589A1 (en) | 2003-07-10 |
US7198893B1 (en) | 2007-04-03 |
DE69738206D1 (de) | 2007-11-22 |
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