AR040711A1 - Un metodo para verificacion de calidad/control de calidad para proceso de bioensayo de alto rendimiento - Google Patents

Un metodo para verificacion de calidad/control de calidad para proceso de bioensayo de alto rendimiento

Info

Publication number
AR040711A1
AR040711A1 AR20030102704A ARP030102704A AR040711A1 AR 040711 A1 AR040711 A1 AR 040711A1 AR 20030102704 A AR20030102704 A AR 20030102704A AR P030102704 A ARP030102704 A AR P030102704A AR 040711 A1 AR040711 A1 AR 040711A1
Authority
AR
Argentina
Prior art keywords
biochip
bioassay
model
sera
quality
Prior art date
Application number
AR20030102704A
Other languages
English (en)
Inventor
Ben Hitt
Peter J Levine
Emmanuel F Petricoin Iii
Original Assignee
Us Agriculture
Correlogic Systems Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Us Agriculture, Correlogic Systems Inc filed Critical Us Agriculture
Publication of AR040711A1 publication Critical patent/AR040711A1/es

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6848—Methods of protein analysis involving mass spectrometry
    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B30/00—Methods of screening libraries
    • C40B30/04—Methods of screening libraries by measuring the ability to specifically bind a target molecule, e.g. antibody-antigen binding, receptor-ligand binding
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B25/00—ICT specially adapted for hybridisation; ICT specially adapted for gene or protein expression
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B40/00—ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B40/00—ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
    • G16B40/10—Signal processing, e.g. from mass spectrometry [MS] or from PCR
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/24—Nuclear magnetic resonance, electron spin resonance or other spin effects or mass spectrometry

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Immunology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Biophysics (AREA)
  • Medical Informatics (AREA)
  • Biotechnology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Theoretical Computer Science (AREA)
  • Evolutionary Biology (AREA)
  • Data Mining & Analysis (AREA)
  • Bioethics (AREA)
  • Public Health (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Evolutionary Computation (AREA)
  • Cell Biology (AREA)
  • Epidemiology (AREA)
  • Databases & Information Systems (AREA)
  • Microbiology (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Software Systems (AREA)
  • Food Science & Technology (AREA)
  • Artificial Intelligence (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Signal Processing (AREA)
  • Chemical Kinetics & Catalysis (AREA)

Abstract

La presente se refiere a un método de verificación de calidad/control de calidad para procesos de bioensayo de alto rendimiento. El método incluye generar un modelo de proceso de bioensayo, y luego comparar los datos espectrales en base a una combinación de un biochip y un suero de prueba con el modelo de proceso de bioensayo para determinar si la muestra y el proceso de bioensayo están produciendo datos aceptables. Alternativamente, el método puede incluir comparar datos espectrales en base a una combinación de suero y diluyentes usados en un proceso de electropulverización con el modelo de proceso de bioensayo. Si el proceso de bioensayo y la muestra de prueba coinciden con el moldeo, el espectro producido puede ser analizado. Reivindicación 1: Un método de verificación de calidad/control de calidad para un proceso de bioensayo de alto rendimiento caracterizado porque comprende: seleccionar un grupo diverso de sueros, el grupo diverso de sueros tiene características distintas; aplicar cada uno de los sueros de grupo diverso a por lo menos un punto en una pluralidad de distintos biochip; realizar una espectrometría de masa en cada uno de la pluralidad de biochips; generar un modelo de biochip basado por lo menos parcialmente en los espectros obtenidos de la pluralidad de distintos sueros o biochips; aplicar un suero de prueba a un punto de un biochip; realizar una espectrometría de masa a un suero de prueba para obtener un espectro asociado con el suero de prueba; hacer coincidir el espectro obtenida de dicha espectrometría con el modelo de biochip; y determinar si el espectro coincide con el modelo de biochip.
AR20030102704A 2002-07-29 2003-07-28 Un metodo para verificacion de calidad/control de calidad para proceso de bioensayo de alto rendimiento AR040711A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US39883102P 2002-07-29 2002-07-29

Publications (1)

Publication Number Publication Date
AR040711A1 true AR040711A1 (es) 2005-04-13

Family

ID=32312442

Family Applications (3)

Application Number Title Priority Date Filing Date
AR20030102705A AR040712A1 (es) 2002-07-29 2003-07-28 Un metodo para inicialar un modelo de control para proceso de bioensayo
AR20030102704A AR040711A1 (es) 2002-07-29 2003-07-28 Un metodo para verificacion de calidad/control de calidad para proceso de bioensayo de alto rendimiento
AR20030102706A AR040713A1 (es) 2002-07-29 2003-07-28 Un metodo para verificacion de calidad/control de calidad para procesos de ionizacion por electro-pulverizacion

Family Applications Before (1)

Application Number Title Priority Date Filing Date
AR20030102705A AR040712A1 (es) 2002-07-29 2003-07-28 Un metodo para inicialar un modelo de control para proceso de bioensayo

Family Applications After (1)

Application Number Title Priority Date Filing Date
AR20030102706A AR040713A1 (es) 2002-07-29 2003-07-28 Un metodo para verificacion de calidad/control de calidad para procesos de ionizacion por electro-pulverizacion

Country Status (5)

Country Link
US (5) US7333896B2 (es)
AR (3) AR040712A1 (es)
AU (3) AU2003268031A1 (es)
TW (3) TW200407540A (es)
WO (3) WO2004011905A2 (es)

Families Citing this family (42)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003535594A (ja) * 2000-06-02 2003-12-02 ラージ スケール プロテオミクス コーポレーション 医薬および関連の毒性についてのタンパク質マーカー
IL153189A0 (en) 2000-06-19 2003-06-24 Correlogic Systems Inc Heuristic method of classification
US6980674B2 (en) * 2000-09-01 2005-12-27 Large Scale Proteomics Corp. Reference database
US6539102B1 (en) * 2000-09-01 2003-03-25 Large Scale Proteomics Reference database
US20030009293A1 (en) * 2001-01-09 2003-01-09 Anderson Norman G. Reference database
US7105810B2 (en) * 2001-12-21 2006-09-12 Cornell Research Foundation, Inc. Electrospray emitter for microfluidic channel
US20020193950A1 (en) * 2002-02-25 2002-12-19 Gavin Edward J. Method for analyzing mass spectra
WO2004011905A2 (en) * 2002-07-29 2004-02-05 Correlogic Systems, Inc. Quality assurance/quality control for electrospray ionization processes
SE0300454D0 (sv) * 2003-02-19 2003-02-19 Aamic Ab Nozzles for electrospray ionization and methods of fabricating them
US7007710B2 (en) * 2003-04-21 2006-03-07 Predicant Biosciences, Inc. Microfluidic devices and methods
US7425700B2 (en) * 2003-05-22 2008-09-16 Stults John T Systems and methods for discovery and analysis of markers
US20040236603A1 (en) * 2003-05-22 2004-11-25 Biospect, Inc. System of analyzing complex mixtures of biological and other fluids to identify biological state information
US7072772B2 (en) * 2003-06-12 2006-07-04 Predicant Bioscience, Inc. Method and apparatus for modeling mass spectrometer lineshapes
US20050255606A1 (en) * 2004-05-13 2005-11-17 Biospect, Inc., A California Corporation Methods for accurate component intensity extraction from separations-mass spectrometry data
AU2004261222A1 (en) * 2003-08-01 2005-02-10 Correlogic Systems, Inc. Multiple high-resolution serum proteomic features for ovarian cancer detection
US7537807B2 (en) * 2003-09-26 2009-05-26 Cornell University Scanned source oriented nanofiber formation
JP4774534B2 (ja) * 2003-12-11 2011-09-14 アングーク ファーマシューティカル カンパニー，リミティド 集中化適応モデル及び遠隔操作サンプルプロセッシングの使用を介した生物学的状態の診断方法
US7608458B2 (en) * 2004-02-05 2009-10-27 Medtronic, Inc. Identifying patients at risk for life threatening arrhythmias
US20050244973A1 (en) * 2004-04-29 2005-11-03 Predicant Biosciences, Inc. Biological patterns for diagnosis and treatment of cancer
US20050287574A1 (en) * 2004-06-23 2005-12-29 Medtronic, Inc. Genetic diagnostic method for SCD risk stratification
US8335652B2 (en) * 2004-06-23 2012-12-18 Yougene Corp. Self-improving identification method
US8027791B2 (en) * 2004-06-23 2011-09-27 Medtronic, Inc. Self-improving classification system
US20060022130A1 (en) * 2004-07-29 2006-02-02 Predicant Biosciences, Inc., A Delaware Corporation Microfluidic devices and methods with integrated electrical contact
US20060060769A1 (en) * 2004-09-21 2006-03-23 Predicant Biosciences, Inc. Electrospray apparatus with an integrated electrode
US7591883B2 (en) * 2004-09-27 2009-09-22 Cornell Research Foundation, Inc. Microfiber supported nanofiber membrane
EP1861704A2 (en) * 2005-02-09 2007-12-05 Correlogic Systems, Inc. Identification of bacteria and spores
US20080312514A1 (en) * 2005-05-12 2008-12-18 Mansfield Brian C Serum Patterns Predictive of Breast Cancer
GB0514553D0 (en) * 2005-07-15 2005-08-24 Nonlinear Dynamics Ltd A method of analysing a representation of a separation pattern
GB0514555D0 (en) * 2005-07-15 2005-08-24 Nonlinear Dynamics Ltd A method of analysing separation patterns
US20070212680A1 (en) * 2006-03-09 2007-09-13 Roche Molecular Systems, Inc. Safety approach for diagnostic systems
US20090106333A1 (en) * 2006-12-29 2009-04-23 Cerner Innovation, Inc. Backing up a protocol order associated with genetic testing
US8224671B2 (en) * 2006-12-29 2012-07-17 Cerner Innovation, Inc. Documentation of protocol orders
US20090112934A1 (en) * 2006-12-29 2009-04-30 Cerner Innovation, Inc. Backing up a protocol order
WO2008100941A2 (en) * 2007-02-12 2008-08-21 Correlogic Systems Inc. A method for calibrating an analytical instrument
SG182976A1 (en) * 2007-06-29 2012-08-30 Ahngook Pharmaceutical Co Ltd Predictive markers for ovarian cancer
WO2009064973A2 (en) * 2007-11-14 2009-05-22 Medtronic Inc. Diagnostic kits and methods for scd or sca therapy selection
US20110143956A1 (en) * 2007-11-14 2011-06-16 Medtronic, Inc. Diagnostic Kits and Methods for SCD or SCA Therapy Selection
GB0814605D0 (en) * 2008-08-11 2008-09-17 Greatvine Ltd Onine management of the provision of advice and services
WO2010132546A2 (en) * 2009-05-12 2010-11-18 Medtronic, Inc. Sca risk stratification by predicting patient response to anti-arrhythmics
US9151769B2 (en) * 2010-07-02 2015-10-06 Idexx Laboratories, Inc. Automated calibration method and system for a diagnostic analyzer
US9087298B2 (en) 2012-12-05 2015-07-21 International Business Machines Corporation Inference of anomalous behavior of members of cohorts and associate actors related to the anomalous behavior based on divergent movement from the cohort context centroid
EP4010456A4 (en) 2019-08-05 2023-09-13 Seer, Inc. SYSTEMS AND METHODS FOR SAMPLE PREPARATION, DATA GENERATION AND ANALYSIS OF CORONA PROTEIN

Family Cites Families (72)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3935562A (en) * 1974-02-22 1976-01-27 Stephens Richard G Pattern recognition method and apparatus
US4075475A (en) * 1976-05-03 1978-02-21 Chemetron Corporation Programmed thermal degradation-mass spectrometry analysis method facilitating identification of a biological specimen
US4122518A (en) * 1976-05-17 1978-10-24 The United States Of America As Represented By The Administrator Of The National Aeronautics & Space Administration Automated clinical system for chromosome analysis
US4697242A (en) * 1984-06-11 1987-09-29 Holland John H Adaptive computing system capable of learning and discovery
GB2187035A (en) 1986-01-27 1987-08-26 Eric James Sjoberg Pyrolysis mass spectrometer disease diagnosis aid
US4881178A (en) * 1987-05-07 1989-11-14 The Regents Of The University Of Michigan Method of controlling a classifier system
US5697369A (en) 1988-12-22 1997-12-16 Biofield Corp. Method and apparatus for disease, injury and bodily condition screening or sensing
WO1991014990A1 (en) * 1990-03-28 1991-10-03 Koza John R Non-linear genetic algorithms for solving problems by finding a fit composition of functions
US5352616A (en) * 1990-06-21 1994-10-04 Axis Biochemicals As Analyte variant analysis
US5210412A (en) * 1991-01-31 1993-05-11 Wayne State University Method for analyzing an organic sample
US5784162A (en) * 1993-08-18 1998-07-21 Applied Spectral Imaging Ltd. Spectral bio-imaging methods for biological research, medical diagnostics and therapy
ATE151546T1 (de) 1991-08-28 1997-04-15 Becton Dickinson Co Schwerkraftsattraktionsmaschine zur anpassungsfähigen autoclusterbildung n- dimensionaler datenströme
US5632957A (en) * 1993-11-01 1997-05-27 Nanogen Molecular biological diagnostic systems including electrodes
RU2038598C1 (ru) 1992-07-06 1995-06-27 Шапиро Светлана Борисовна Способ уринодиагностики заболеваний почек
US6114114A (en) * 1992-07-17 2000-09-05 Incyte Pharmaceuticals, Inc. Comparative gene transcript analysis
DE69334349D1 (de) * 1992-09-01 2011-04-21 Apple Inc Verbesserte Vektorquatisierung
US5790761A (en) 1992-12-11 1998-08-04 Heseltine; Gary L. Method and apparatus for the diagnosis of colorectal cancer
AU676582B2 (en) * 1993-05-28 1997-03-13 Baylor College Of Medicine Method and apparatus for desorption and ionization of analytes
US5995645A (en) * 1993-08-18 1999-11-30 Applied Spectral Imaging Ltd. Method of cancer cell detection
US5352613A (en) * 1993-10-07 1994-10-04 Tafas Triantafillos P Cytological screening method
US5553616A (en) * 1993-11-30 1996-09-10 Florida Institute Of Technology Determination of concentrations of biological substances using raman spectroscopy and artificial neural network discriminator
US6025128A (en) * 1994-09-29 2000-02-15 The University Of Tulsa Prediction of prostate cancer progression by analysis of selected predictive parameters
WO1996012187A1 (en) * 1994-10-13 1996-04-25 Horus Therapeutics, Inc. Computer assisted methods for diagnosing diseases
US5848177A (en) * 1994-12-29 1998-12-08 Board Of Trustees Operating Michigan State University Method and system for detection of biological materials using fractal dimensions
GB2301897B (en) * 1995-06-08 1999-05-26 Univ Wales Aberystwyth The Composition analysis
KR100197580B1 (ko) * 1995-09-13 1999-06-15 이민화 무선 통신망을 이용한 실시간 생체신호모니터링시스템
US5716825A (en) 1995-11-01 1998-02-10 Hewlett Packard Company Integrated nucleic acid analysis system for MALDI-TOF MS
US5687716A (en) 1995-11-15 1997-11-18 Kaufmann; Peter Selective differentiating diagnostic process based on broad data bases
DE19543020A1 (de) * 1995-11-18 1997-05-22 Boehringer Mannheim Gmbh Verfahren und Vorrichtung zur Bestimmung von analytischen Daten über das Innere einer streuenden Matrix
SE9602545L (sv) 1996-06-25 1997-12-26 Michael Mecklenburg Metod för att diskriminera komplexa biologiska prover
US5839438A (en) 1996-09-10 1998-11-24 Neuralmed, Inc. Computer-based neural network system and method for medical diagnosis and interpretation
US6571227B1 (en) * 1996-11-04 2003-05-27 3-Dimensional Pharmaceuticals, Inc. Method, system and computer program product for non-linear mapping of multi-dimensional data
EP0935789A1 (en) * 1996-11-04 1999-08-18 3-Dimensional Pharmaceuticals, Inc. System, method, and computer program product for the visualization and interactive processing and analysis of chemical data
US20030129589A1 (en) * 1996-11-06 2003-07-10 Hubert Koster Dna diagnostics based on mass spectrometry
BR9806626A (pt) * 1997-03-10 2001-03-20 Galvak S A De C V Método e aparelho para operar um sistema para galvanizar lâmina de aço
IL131843A (en) * 1997-03-24 2004-06-20 Univ Kingston A method for detecting coincidences, products and devices
US5905258A (en) * 1997-06-02 1999-05-18 Advanced Research & Techology Institute Hybrid ion mobility and mass spectrometer
NZ516848A (en) * 1997-06-20 2004-03-26 Ciphergen Biosystems Inc Retentate chromatography apparatus with applications in biology and medicine
US6081797A (en) * 1997-07-09 2000-06-27 American Heuristics Corporation Adaptive temporal correlation network
US5945640A (en) * 1997-08-01 1999-08-31 3M Innovative Properties Company Stethoscope chestpiece having two suspended diaphragms
US5974412A (en) * 1997-09-24 1999-10-26 Sapient Health Network Intelligent query system for automatically indexing information in a database and automatically categorizing users
CA2321160A1 (en) 1998-02-13 1999-08-19 Oxford Glycosciences (Uk) Ltd. Methods and compositions for diagnosis of hepatoma
GB9805477D0 (en) 1998-03-13 1998-05-13 Oxford Glycosciences Limited Methods and compositions for diagnosis of rheumatoid arthritis
US6128608A (en) 1998-05-01 2000-10-03 Barnhill Technologies, Llc Enhancing knowledge discovery using multiple support vector machines
US6723564B2 (en) 1998-05-07 2004-04-20 Sequenom, Inc. IR MALDI mass spectrometry of nucleic acids using liquid matrices
JP2002514762A (ja) 1998-05-09 2002-05-21 アイコニシス，インコーポレーテッド コンピュータによって制御された、胎児細胞を含む希少細胞に基づく診断のための方法および装置
US5989824A (en) * 1998-11-04 1999-11-23 Mesosystems Technology, Inc. Apparatus and method for lysing bacterial spores to facilitate their identification
EP1153300A2 (en) 1999-02-16 2001-11-14 THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES Lcm (laser capture microdissection) for cellular protein analysis
GB9905817D0 (en) 1999-03-12 1999-05-05 Oxford Glycosciences Uk Ltd Methods
US6631333B1 (en) * 1999-05-10 2003-10-07 California Institute Of Technology Methods for remote characterization of an odor
US6329652B1 (en) 1999-07-28 2001-12-11 Eastman Kodak Company Method for comparison of similar samples in liquid chromatography/mass spectrometry
US6615199B1 (en) * 1999-08-31 2003-09-02 Accenture, Llp Abstraction factory in a base services pattern environment
AU7586100A (en) 1999-09-17 2001-04-17 Affymetrix, Inc. Method of cluster analysis of gene expression profiles
WO2001031579A2 (en) 1999-10-27 2001-05-03 Barnhill Technologies, Llc Methods and devices for identifying patterns in biological patterns
EP2357582A1 (en) 1999-10-27 2011-08-17 Health Discovery Corporation Methods and devices for identifying patterns in biological systems
DE10021737C2 (de) 2000-05-04 2002-10-17 Hermann Haller Verfahren und Vorrichtung zur qualitativen und/oder quantitativen Bestimmung eines Protein- und/oder Peptidmusters einer Flüssigkeitsprobe, die dem menschlichen oder tierischen Körper entnommen wird
IL153189A0 (en) * 2000-06-19 2003-06-24 Correlogic Systems Inc Heuristic method of classification
US6680203B2 (en) * 2000-07-10 2004-01-20 Esperion Therapeutics, Inc. Fourier transform mass spectrometry of complex biological samples
WO2002007064A2 (en) * 2000-07-17 2002-01-24 Labnetics, Inc. Method and apparatus for the processing of remotely collected electronic information characterizing properties of biological entities
KR101054732B1 (ko) 2000-07-18 2011-08-05 더 유나이티드 스테이츠 오브 아메리카 애즈 리프리젠티드 바이 더 세크레터리 오브 더 디파트먼트 오브 헬쓰 앤드 휴먼 써비시즈 생물학적 데이터의 숨겨진 패턴에 근거한 생물학적 상태의 식별 방법
JP2004522980A (ja) 2000-11-16 2004-07-29 シファーゲン バイオシステムズ， インコーポレイテッド 質量スペクトルを分析する方法
AU2002253879B2 (en) 2001-01-24 2007-07-12 Health Discovery Corporation Methods of identifying patterns in biological systems and uses thereof
CA2438391A1 (en) 2001-02-16 2002-10-10 William E. Rich Method for correlating gene expression profiles with protein expression profiles
US20030077616A1 (en) * 2001-04-19 2003-04-24 Ciphergen Biosystems, Inc. Biomolecule characterization using mass spectrometry and affinity tags
US20020160420A1 (en) 2001-04-30 2002-10-31 George Jackowski Process for diagnosis of physiological conditions by characterization of proteomic materials
WO2003014735A1 (en) * 2001-08-03 2003-02-20 General Hospital Corporation System, process and diagnostic arrangement establishing and monitoring medication doses for patients
WO2003017177A2 (en) * 2001-08-13 2003-02-27 Beyong Genomics, Inc. Method and system for profiling biological systems
US20020193950A1 (en) * 2002-02-25 2002-12-19 Gavin Edward J. Method for analyzing mass spectra
WO2004011905A2 (en) * 2002-07-29 2004-02-05 Correlogic Systems, Inc. Quality assurance/quality control for electrospray ionization processes
JP4585167B2 (ja) * 2002-11-29 2010-11-24 東芝医用システムエンジニアリング株式会社 Ｘ線コンピュータ断層撮影システム
AU2004261222A1 (en) * 2003-08-01 2005-02-10 Correlogic Systems, Inc. Multiple high-resolution serum proteomic features for ovarian cancer detection
JP4774534B2 (ja) * 2003-12-11 2011-09-14 アングーク ファーマシューティカル カンパニー，リミティド 集中化適応モデル及び遠隔操作サンプルプロセッシングの使用を介した生物学的状態の診断方法

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WO2004011904A3 (en) 2004-07-08
AU2003268031A1 (en) 2004-02-16
TW200403434A (en) 2004-03-01
US7333896B2 (en) 2008-02-19
US7395160B2 (en) 2008-07-01
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