HK1022840A1 - Pellets having a core coated with an antifungal and a polymer - Google Patents

Pellets having a core coated with an antifungal and a polymer

Info

Publication number
HK1022840A1
HK1022840A1 HK00101919A HK00101919A HK1022840A1 HK 1022840 A1 HK1022840 A1 HK 1022840A1 HK 00101919 A HK00101919 A HK 00101919A HK 00101919 A HK00101919 A HK 00101919A HK 1022840 A1 HK1022840 A1 HK 1022840A1
Authority
HK
Hong Kong
Prior art keywords
antifungal
pellets
polymer
core coated
coated
Prior art date
Application number
HK00101919A
Other languages
English (en)
Inventor
Roger Petrus Gerebe Vandecruys
Conde Valentin Florent Vict De
Paul Marie Victor Gilis
Josef Peeters
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of HK1022840A1 publication Critical patent/HK1022840A1/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Dermatology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
HK00101919A 1997-03-26 2000-03-29 Pellets having a core coated with an antifungal and a polymer HK1022840A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP97200914 1997-03-26
PCT/EP1998/001773 WO1998042318A1 (en) 1997-03-26 1998-03-18 Pellets having a core coated with an antifungal and a polymer

Publications (1)

Publication Number Publication Date
HK1022840A1 true HK1022840A1 (en) 2000-08-25

Family

ID=8228147

Family Applications (1)

Application Number Title Priority Date Filing Date
HK00101919A HK1022840A1 (en) 1997-03-26 2000-03-29 Pellets having a core coated with an antifungal and a polymer

Country Status (31)

Country Link
EP (1) EP0969821B1 (hu)
JP (1) JP3608800B2 (hu)
KR (1) KR100520936B1 (hu)
CN (1) CN1206984C (hu)
AP (1) AP1227A (hu)
AT (1) ATE241969T1 (hu)
AU (1) AU734248B2 (hu)
BG (1) BG64434B1 (hu)
BR (1) BR9806174A (hu)
CA (1) CA2269501C (hu)
CY (1) CY2384B1 (hu)
CZ (1) CZ295502B6 (hu)
DE (1) DE69815316T2 (hu)
DK (1) DK0969821T3 (hu)
EE (1) EE03904B1 (hu)
ES (1) ES2201485T3 (hu)
HK (1) HK1022840A1 (hu)
HU (1) HU224217B1 (hu)
ID (1) ID21477A (hu)
IL (1) IL129575A (hu)
NO (1) NO325102B1 (hu)
NZ (1) NZ335364A (hu)
OA (1) OA11162A (hu)
PL (1) PL190566B1 (hu)
PT (1) PT969821E (hu)
RU (1) RU2218153C2 (hu)
SI (1) SI0969821T1 (hu)
SK (1) SK284813B6 (hu)
TR (1) TR199900990T2 (hu)
UA (1) UA60318C2 (hu)
WO (1) WO1998042318A1 (hu)

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ES2157731B1 (es) 1998-07-21 2002-05-01 Liconsa Liberacion Controlada Preparacion farmaceutica oral de un compuesto de actividad antifungica y procedimiento para su preparacion.
CN1156461C (zh) 1999-03-24 2004-07-07 R·P·希拉技术股份有限公司 改良的水溶性药物制剂
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CA2444895C (en) 2001-05-11 2011-02-15 Tibotec Pharmaceuticals Ltd. Broadspectrum 2-amino-benzoxazole sulfonamide hiv protease inhibitors
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US8071133B2 (en) 2001-08-20 2011-12-06 Stiefel Laboratories, Inc. Oral dosage forms of water insoluble drugs and methods of making the same
PL216539B1 (pl) 2001-12-21 2014-04-30 Tibotec Pharm Ltd Związki fenylosulfonylowe i zastosowanie związków fenylosulfonylowych
MY142238A (en) 2002-03-12 2010-11-15 Tibotec Pharm Ltd Broadspectrum substituted benzimidazole sulfonamide hiv protease inhibitors
NZ536496A (en) 2002-05-17 2006-06-30 Tibotec Pharm Ltd Broadspectrum substituted benzisoxazole sulfonamide HIV protease inhibitors
KR100994759B1 (ko) 2002-08-14 2010-11-16 티보텍 파마슈티컬즈 광역스펙트럼의 치환된 옥신돌 설폰아미드 ｈｉｖ프로테아제 저해제
KR100557680B1 (ko) * 2002-11-23 2006-03-07 한국유나이티드제약 주식회사 이트라코나졸의 용해도 개선을 위한 펠렛제제 및 그제조방법
EP1438960B2 (en) * 2003-01-14 2012-12-19 Acino Pharma AG Compostion of itraconazole dispersed in a hydrophilic polymer having enhanced bioavailability
EP1438961B2 (en) * 2003-01-14 2014-08-20 Acino Pharma AG Bioequivalent composition of itraconazole dispersed in a hydrophilic polymer
JP2007501256A (ja) 2003-08-06 2007-01-25 ムルイェ、ニルマル 水溶性薬物を含有する医薬組成物
SG145742A1 (en) 2003-09-11 2008-09-29 Tibotec Pharm Ltd Entry inhibitors of the hiv virus
EP1568369A1 (en) 2004-02-23 2005-08-31 Boehringer Ingelheim Vetmedica Gmbh Use of meloxicam for the treatment of respiratory diseases in pigs
AR048650A1 (es) 2004-05-04 2006-05-10 Tibotec Pharm Ltd Derivados de (1,10b-dihidro-2-(aminocarbonil-fenil)-5h-pirazolo[1,5 c][1,3]benzoxazin-5-il)fenil metanona como inhibidores de la replicacion viral del vih
JP5073480B2 (ja) 2004-05-07 2012-11-14 セコイア、ファーマシューティカルズ、インコーポレイテッド 耐性防止レトロウイルスプロテアーゼ阻害薬
TW200613307A (en) 2004-05-17 2006-05-01 Tibotec Pharm Ltd 4-substituted-1,5-dihydro-pyrido[3,2-b]indol-2-ones
ATE481403T1 (de) 2004-05-17 2010-10-15 Tibotec Pharm Ltd Substituierte 1-phenyl-1,5-dihydro-pyridoä3,2- büindol-2-on-derivate verwendbar als pharmazeutische antiinfektiva
CN1953983B (zh) 2004-05-17 2010-05-26 泰博特克药品有限公司 1-杂环基-1,5-二氢-吡啶并[3,2-b]吲哚-2-酮
MX2008012790A (es) 2006-04-03 2008-10-15 Tibotec Pharm Ltd 3,4-dihidro-imidazo[4,5-b]piridin-5-onas inhibidoras de virus de inmunodeficiencia humana.
ZA200901162B (en) * 2006-09-04 2010-06-30 Panacea Biotec Ltd Programmable buoyant delivery technology
KR100809903B1 (ko) * 2006-09-05 2008-03-06 주식회사유한양행 안정화된 클로피도그렐-함유 입자, 그의 제조방법, 및 이를포함하는 약학 조성물
CN101283984B (zh) * 2007-04-12 2010-05-26 永胜药品工业股份有限公司 高生物使用率的经杀真菌剂和聚合物涂覆的核心微粒状物
JP2008280254A (ja) * 2007-05-08 2008-11-20 Everest Pharm Industrial Co Ltd 生体に使用される比率が高い、殺菌剤と重合物を塗粧してる核心微粒状物
US8313527B2 (en) 2007-11-05 2012-11-20 Allergan, Inc. Soft prosthesis shell texturing method
US8569364B2 (en) 2007-11-28 2013-10-29 Sequoia Pharmaceuticals, Inc. 5-substituted benzofurans as inhibitors of cytochrome P450 2D6
CA2716348C (en) 2008-02-21 2017-04-04 Sequoia Pharmaceuticals, Inc. Diamide inhibitors of cytochrome p450
US9050184B2 (en) 2008-08-13 2015-06-09 Allergan, Inc. Dual plane breast implant
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AU731704B2 (en) * 1996-06-28 2001-04-05 Schering Corporation Oral composition comprising a triazole antifungal compound

Also Published As

Publication number Publication date
JP2001520663A (ja) 2001-10-30
EE03904B1 (et) 2002-12-16
AP9901516A0 (en) 1999-06-30
TR199900990T2 (xx) 1999-10-21
HUP0002056A2 (hu) 2000-12-28
UA60318C2 (uk) 2003-10-15
BG103356A (en) 2000-03-31
CY2384B1 (en) 2004-06-04
SK284813B6 (sk) 2005-12-01
IL129575A (en) 2004-06-20
BR9806174A (pt) 1999-10-19
DK0969821T3 (da) 2003-09-15
OA11162A (en) 2003-04-16
DE69815316T2 (de) 2004-04-29
NO325102B1 (no) 2008-02-04
IL129575A0 (en) 2000-02-29
KR20000052971A (ko) 2000-08-25
AU734248B2 (en) 2001-06-07
ATE241969T1 (de) 2003-06-15
EP0969821B1 (en) 2003-06-04
PT969821E (pt) 2003-10-31
SK54499A3 (en) 2000-01-18
CN1206984C (zh) 2005-06-22
SI0969821T1 (en) 2003-10-31
EP0969821A1 (en) 2000-01-12
NO992114L (no) 1999-08-26
CZ139899A3 (cs) 1999-10-13
HU224217B1 (hu) 2005-06-28
RU2218153C2 (ru) 2003-12-10
NZ335364A (en) 2000-08-25
CN1244796A (zh) 2000-02-16
KR100520936B1 (ko) 2005-10-17
EE9900453A (et) 2000-04-17
WO1998042318A1 (en) 1998-10-01
AP1227A (en) 2003-11-24
DE69815316D1 (de) 2003-07-10
JP3608800B2 (ja) 2005-01-12
NO992114D0 (no) 1999-04-30
CA2269501C (en) 2005-11-08
ES2201485T3 (es) 2004-03-16
CZ295502B6 (cs) 2005-08-17
HUP0002056A3 (en) 2001-01-29
PL335542A1 (en) 2000-04-25
AU7210798A (en) 1998-10-20
BG64434B1 (en) 2005-02-28
ID21477A (id) 1999-06-17
PL190566B1 (pl) 2005-12-30
CA2269501A1 (en) 1998-10-01

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Effective date: 20180317