HK1015781A1 - Novel heterocyclic derivatives and medicinal use thereof - Google Patents

Novel heterocyclic derivatives and medicinal use thereof

Info

Publication number
HK1015781A1
HK1015781A1 HK99100913A HK99100913A HK1015781A1 HK 1015781 A1 HK1015781 A1 HK 1015781A1 HK 99100913 A HK99100913 A HK 99100913A HK 99100913 A HK99100913 A HK 99100913A HK 1015781 A1 HK1015781 A1 HK 1015781A1
Authority
HK
Hong Kong
Prior art keywords
heterocyclic derivatives
medicinal use
novel heterocyclic
arteriosclerosis
useful
Prior art date
Application number
HK99100913A
Other languages
English (en)
Inventor
Shoji Kamiya
Hiroaki Shirahase
Hiroshi Matsui
Shohei Nakamura
Katsuo Wada
Original Assignee
Kyoto Pharma Ind
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kyoto Pharma Ind filed Critical Kyoto Pharma Ind
Priority to HK03100740.0A priority Critical patent/HK1048989B/zh
Publication of HK1015781A1 publication Critical patent/HK1015781A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pyrrole Compounds (AREA)
HK99100913A 1995-10-05 1999-03-05 Novel heterocyclic derivatives and medicinal use thereof HK1015781A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
HK03100740.0A HK1048989B (zh) 1995-10-05 1999-03-05 雜環衍生物及其醫藥用途

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP25908295 1995-10-05
JP5801896 1996-03-14
JP19433196 1996-07-24
PCT/JP1996/002852 WO1997012860A1 (fr) 1995-10-05 1996-09-30 Nouveaux derives heterocycliques et leur utilisation medicinale

Publications (1)

Publication Number Publication Date
HK1015781A1 true HK1015781A1 (en) 1999-10-22

Family

ID=27296460

Family Applications (2)

Application Number Title Priority Date Filing Date
HK03100740.0A HK1048989B (zh) 1995-10-05 1999-03-05 雜環衍生物及其醫藥用途
HK99100913A HK1015781A1 (en) 1995-10-05 1999-03-05 Novel heterocyclic derivatives and medicinal use thereof

Family Applications Before (1)

Application Number Title Priority Date Filing Date
HK03100740.0A HK1048989B (zh) 1995-10-05 1999-03-05 雜環衍生物及其醫藥用途

Country Status (20)

Country Link
US (3) US6063806A (xx)
EP (1) EP0866059B1 (xx)
KR (1) KR100388345B1 (xx)
CN (2) CN1097043C (xx)
AT (1) ATE210116T1 (xx)
BR (1) BR9610846A (xx)
CZ (1) CZ292632B6 (xx)
DE (1) DE69617731T2 (xx)
DK (1) DK0866059T3 (xx)
ES (1) ES2164920T3 (xx)
HK (2) HK1048989B (xx)
HU (1) HUP9900617A3 (xx)
IL (1) IL123939A (xx)
NO (1) NO310818B1 (xx)
NZ (1) NZ318874A (xx)
PL (1) PL190034B1 (xx)
PT (1) PT866059E (xx)
TR (1) TR199800655T2 (xx)
TW (1) TW429250B (xx)
WO (1) WO1997012860A1 (xx)

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AR015425A1 (es) * 1997-09-05 2001-05-02 Smithkline Beecham Corp Compuestos de benzotiazol, composicion farmaceutica que los contiene, su uso en la manufactura de un medicamento, procedimiento para su preparacion,compuestos intermediarios y procedimiento para su preparacion
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IL140983A0 (en) * 1998-07-23 2002-02-10 Smithkline Beecham Corp Il-8 receptor antagonists
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AU2001282541B2 (en) * 2000-09-01 2004-06-24 Sankyo Company, Limited Medicinal compositions
TW200600497A (en) * 2001-02-02 2006-01-01 Sankyo Co Preparation of indoline derivative
WO2002072147A1 (fr) * 2001-03-14 2002-09-19 Sankyo Company, Limited Compositions medicinales contenant un inhibiteur de transporteur d'acide biliaire
EP2335700A1 (en) * 2001-07-25 2011-06-22 Boehringer Ingelheim (Canada) Ltd. Hepatitis C virus polymerase inhibitors with a heterobicylic structure
NZ531346A (en) * 2001-08-28 2005-10-28 Sankyo Co Medicinal compositions containing angiotensin II receptor antagonist
US20050119314A1 (en) * 2002-04-05 2005-06-02 Sankyo Company, Limited Pharmaceutical composition comprising an ACAT inhibitor and an insulin resistance reducing agent
KR20040099394A (ko) * 2002-04-05 2004-11-26 상꾜 가부시키가이샤 Ａｃａｔ 저해제 및 인슐린 저항성 개선제를 함유하는의약 조성물
JP2004002365A (ja) * 2002-04-05 2004-01-08 Sankyo Co Ltd Ａｃａｔ阻害剤とインシュリン抵抗性改善剤とからなる医薬組成物
MXPA05000749A (es) * 2002-07-17 2005-04-28 Kyoto Pharma Ind Nuevos compuestos de indolina y uso medico del mismo.
US20050192245A1 (en) * 2002-07-18 2005-09-01 Sankyo Company, Limited Medicinal composition for treating arteriosclerosis
RU2005104432A (ru) * 2002-07-18 2005-08-10 Санкио Компани, Лимитед (Jp) Лекарственная композиция для лечения артериосклероза
US7098231B2 (en) * 2003-01-22 2006-08-29 Boehringer Ingelheim International Gmbh Viral polymerase inhibitors
US7223785B2 (en) * 2003-01-22 2007-05-29 Boehringer Ingelheim International Gmbh Viral polymerase inhibitors
CN1882327A (zh) 2003-11-19 2006-12-20 症变治疗公司 含磷的新的拟甲状腺素药
WO2005077359A1 (ja) * 2004-02-17 2005-08-25 Sankyo Company, Limited インドリン化合物を含有する安定化された医薬組成物
ES2431314T3 (es) * 2004-02-20 2013-11-26 Boehringer Ingelheim International Gmbh Inhibidores de polimerasa vírica
CA2624601C (en) 2004-10-06 2018-07-03 The Brigham And Women's Hospital, Inc. Relevance of achieved levels of markers of systemic inflammation following treatment
BRPI0518229A (pt) * 2004-10-27 2008-11-04 Daiichi Sankyo Co Ltd composto de benzeno tendo 2 ou mais substituintes
CA2618682C (en) * 2005-08-12 2011-06-21 Boehringer Ingelheim International Gmbh Viral polymerase inhibitors
WO2007146230A2 (en) * 2006-06-14 2007-12-21 Merck & Co., Inc. Non-nucleoside reverse transcriptase inhibitors
FR2918890A1 (fr) * 2007-07-19 2009-01-23 Galderma Res & Dev Utilisation du pactimibe pour la preparation d'un medicament destine a prevenir ou a traiter une maladie due a un dysfonctionnement des glandes sebacees chez l'homme ou l'animal
WO2010093601A1 (en) 2009-02-10 2010-08-19 Metabasis Therapeutics, Inc. Novel sulfonic acid-containing thyromimetics, and methods for their use
US8343706B2 (en) * 2010-01-25 2013-01-01 International Business Machines Corporation Fluorine-free fused ring heteroaromatic photoacid generators and resist compositions containing the same
WO2011161964A1 (ja) * 2010-06-24 2011-12-29 興和株式会社 Ａｃａｔ阻害剤を有効成分とするインスリン抵抗性改善剤
WO2014139388A1 (en) * 2013-03-14 2014-09-18 Merck Sharp & Dohme Corp. Novel indole derivatives useful as anti-diabetic agents
JP2018052818A (ja) * 2015-01-28 2018-04-05 武田薬品工業株式会社 スルホンアミド化合物
CN108440373B (zh) * 2018-03-23 2021-05-14 昆明学院 一种铁催化的氰烷基吲哚啉及其制备方法

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FR2673625B1 (fr) 1991-03-08 1993-05-07 Adir Nouveaux derives d'acylaminophenol, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
FR2674522B1 (fr) * 1991-03-26 1993-07-16 Lipha Nouveaux derives de l'indole, procedes de preparation et medicaments les contenant.
IL101785A0 (en) * 1991-05-10 1992-12-30 Fujisawa Pharmaceutical Co Urea derivatives,processes for the preparation thereof and pharmaceutical compositions containing the same
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Also Published As

Publication number Publication date
TR199800655T2 (xx) 1999-09-21
KR19990063987A (ko) 1999-07-26
BR9610846A (pt) 1999-07-13
NZ318874A (en) 1999-09-29
EP0866059A1 (en) 1998-09-23
KR100388345B1 (ko) 2004-03-30
AU7097796A (en) 1997-04-28
CZ292632B6 (cs) 2003-11-12
PT866059E (pt) 2002-03-28
HUP9900617A2 (hu) 1999-06-28
USRE38970E1 (en) 2006-02-07
CN1097043C (zh) 2002-12-25
NO981485D0 (no) 1998-04-01
DE69617731T2 (de) 2002-08-08
IL123939A (en) 2001-11-25
CN1361100A (zh) 2002-07-31
PL326000A1 (en) 1998-08-17
ES2164920T3 (es) 2002-03-01
CN1193018C (zh) 2005-03-16
US6200988B1 (en) 2001-03-13
DE69617731D1 (de) 2002-01-17
CZ99698A3 (cs) 1998-08-12
CN1203587A (zh) 1998-12-30
EP0866059A4 (en) 1998-12-02
TW429250B (en) 2001-04-11
NO310818B1 (no) 2001-09-03
NO981485L (no) 1998-06-02
DK0866059T3 (da) 2002-03-25
AU708571B2 (en) 1999-08-05
WO1997012860A1 (fr) 1997-04-10
PL190034B1 (pl) 2005-10-31
HK1048989B (zh) 2005-10-28
HK1048989A1 (en) 2003-04-25
US6063806A (en) 2000-05-16
HUP9900617A3 (en) 2001-12-28
ATE210116T1 (de) 2001-12-15
EP0866059B1 (en) 2001-12-05

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Legal Events

Date Code Title Description
PF Patent in force
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20080930