HK1006710A1 - N-(aryloxyalkyl)heteroarylpiperidines and-heteroarylpiperazines, a process for their preparation and their use as medicaments - Google Patents

N-(aryloxyalkyl)heteroarylpiperidines and-heteroarylpiperazines, a process for their preparation and their use as medicaments Download PDF

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Publication number
HK1006710A1
HK1006710A1 HK98105870A HK98105870A HK1006710A1 HK 1006710 A1 HK1006710 A1 HK 1006710A1 HK 98105870 A HK98105870 A HK 98105870A HK 98105870 A HK98105870 A HK 98105870A HK 1006710 A1 HK1006710 A1 HK 1006710A1
Authority
HK
Hong Kong
Prior art keywords
ethanone
piperidinyl
methoxyphenyl
fluoro
compound
Prior art date
Application number
HK98105870A
Other languages
German (de)
English (en)
French (fr)
Chinese (zh)
Other versions
HK1006710B (en
Inventor
Thomas Strupczewski Joseph
Cleveland Helsley Grover
Chiang Yulin
J. Bordeau Kenneth
Original Assignee
Hoechst-Roussel Pharmaceutical Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst-Roussel Pharmaceutical Inc. filed Critical Hoechst-Roussel Pharmaceutical Inc.
Publication of HK1006710B publication Critical patent/HK1006710B/en
Publication of HK1006710A1 publication Critical patent/HK1006710A1/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/54—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings condensed with carbocyclic rings or ring systems
    • C07D231/56—Benzopyrazoles; Hydrogenated benzopyrazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/20—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings condensed with carbocyclic rings or ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D275/00—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings
    • C07D275/04—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings condensed with carbocyclic rings or ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
HK98105870A 1989-05-19 1998-06-22 N-(aryloxyalkyl)heteroarylpiperidines and-heteroarylpiperazines, a process for their preparation and their use as medicaments HK1006710A1 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US35441189A 1989-05-19 1989-05-19
US354411 1989-05-19
US45679089A 1989-12-29 1989-12-29
US456790 1989-12-29

Publications (2)

Publication Number Publication Date
HK1006710B HK1006710B (en) 1999-03-12
HK1006710A1 true HK1006710A1 (en) 1999-03-12

Family

ID=26998389

Family Applications (1)

Application Number Title Priority Date Filing Date
HK98105870A HK1006710A1 (en) 1989-05-19 1998-06-22 N-(aryloxyalkyl)heteroarylpiperidines and-heteroarylpiperazines, a process for their preparation and their use as medicaments

Country Status (24)

Country Link
EP (1) EP0402644B1 (cs)
JP (1) JPH0662580B2 (cs)
KR (1) KR0157308B1 (cs)
CN (2) CN1086387C (cs)
AT (1) ATE126512T1 (cs)
AU (1) AU640653B2 (cs)
CA (1) CA2017193C (cs)
CZ (1) CZ282385B6 (cs)
DD (1) DD300433A5 (cs)
DE (1) DE69021645T2 (cs)
DK (1) DK0402644T3 (cs)
ES (1) ES2076253T3 (cs)
FI (2) FI104072B (cs)
GR (1) GR3017447T3 (cs)
HK (1) HK1006710A1 (cs)
HU (2) HU218200B (cs)
IE (1) IE68431B1 (cs)
IL (1) IL94425A (cs)
NO (1) NO177301C (cs)
NZ (1) NZ233710A (cs)
PL (1) PL163965B1 (cs)
PT (1) PT94084B (cs)
RU (3) RU2062776C1 (cs)
SK (1) SK242590A3 (cs)

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US5328920A (en) * 1991-04-17 1994-07-12 Hoechst-Roussel Pharmaceuticals Incorporated Substituted (pyridinylamino)-indoles
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NZ245260A (en) * 1991-11-27 1995-06-27 Novo Nordisk As Piperidine derivatives, preparation and pharmaceutical compositions thereof
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DK60593D0 (da) * 1993-05-26 1993-05-26 Novo Nordisk As Kemiske forbindelser, deres fremstilling og anvendelse
DK60793D0 (da) * 1993-05-26 1993-05-26 Novo Nordisk As Kemiske forbindelser, deres fremstilling og anvendelse
GB9318691D0 (en) * 1993-09-09 1993-10-27 Merck Sharp & Dohme Therapeutic agents
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JP3274579B2 (ja) * 1995-01-12 2002-04-15 住友製薬株式会社 脳血管障害に伴う精神症候治療剤
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AU2006201188B2 (en) * 2001-02-05 2007-11-15 Novartis Ag New use of iloperidone
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Also Published As

Publication number Publication date
CN1223348C (zh) 2005-10-19
HU218200B (hu) 2000-06-28
EP0402644A1 (en) 1990-12-19
EP0402644B1 (en) 1995-08-16
NO902214L (no) 1990-11-20
DD300433A5 (de) 1992-06-11
RU2062776C1 (ru) 1996-06-27
IE68431B1 (en) 1996-06-12
IL94425A0 (en) 1991-03-10
FI19991869L (fi) 1999-09-02
HU211853A9 (en) 1995-12-28
CZ242590A3 (en) 1997-03-12
JPH0363263A (ja) 1991-03-19
HK1038316A1 (en) 2002-03-15
CN1305812A (zh) 2001-08-01
JPH0662580B2 (ja) 1994-08-17
DK0402644T3 (da) 1996-01-02
FI19991869A7 (fi) 1999-09-02
ATE126512T1 (de) 1995-09-15
CA2017193C (en) 2000-06-27
CA2017193A1 (en) 1990-11-19
KR0157308B1 (ko) 1998-11-16
NO177301C (no) 1995-08-23
FI104072B1 (fi) 1999-11-15
IL94425A (en) 1994-02-27
NZ233710A (en) 1992-05-26
CN1048037A (zh) 1990-12-26
HUT58720A (en) 1992-03-30
HU903090D0 (en) 1990-09-28
ES2076253T3 (es) 1995-11-01
AU640653B2 (en) 1993-09-02
DE69021645T2 (de) 1996-02-22
GR3017447T3 (en) 1995-12-31
RU2239434C2 (ru) 2004-11-10
PT94084B (pt) 1996-12-31
PL163965B1 (pl) 1994-05-31
NO902214D0 (no) 1990-05-18
FI902449A0 (fi) 1990-05-17
RU2147583C1 (ru) 2000-04-20
AU5577090A (en) 1990-11-22
IE901809L (en) 1990-11-19
PT94084A (pt) 1991-01-08
DE69021645D1 (de) 1995-09-21
KR900018070A (ko) 1990-12-20
PL285247A1 (en) 1991-02-11
NO177301B (no) 1995-05-15
CZ282385B6 (cs) 1997-07-16
SK279474B6 (sk) 1998-11-04
CN1086387C (zh) 2002-06-19
FI104072B (fi) 1999-11-15
SK242590A3 (en) 1998-11-04

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