HK1003561A1 - Modafinil composition of defined particle size - Google Patents

Modafinil composition of defined particle size

Info

Publication number
HK1003561A1
HK1003561A1 HK98102611A HK98102611A HK1003561A1 HK 1003561 A1 HK1003561 A1 HK 1003561A1 HK 98102611 A HK98102611 A HK 98102611A HK 98102611 A HK98102611 A HK 98102611A HK 1003561 A1 HK1003561 A1 HK 1003561A1
Authority
HK
Hong Kong
Prior art keywords
particle size
modafinil
defined particle
modafinil composition
composition
Prior art date
Application number
HK98102611A
Other languages
English (en)
Inventor
Peter E Grebow
Vincent Corvari
David Stong
Original Assignee
Cephalon Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23240954&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HK1003561(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Cephalon Inc filed Critical Cephalon Inc
Publication of HK1003561A1 publication Critical patent/HK1003561A1/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Pain & Pain Management (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Electrochromic Elements, Electrophoresis, Or Variable Reflection Or Absorption Elements (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Developing Agents For Electrophotography (AREA)
  • Paints Or Removers (AREA)
  • Adhesives Or Adhesive Processes (AREA)
  • Packaging For Recording Disks (AREA)
  • Laminated Bodies (AREA)
  • Slot Machines And Peripheral Devices (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Oscillators With Electromechanical Resonators (AREA)
HK98102611A 1994-10-06 1998-03-27 Modafinil composition of defined particle size HK1003561A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/319,124 US5618845A (en) 1994-10-06 1994-10-06 Acetamide derivative having defined particle size

Publications (1)

Publication Number Publication Date
HK1003561A1 true HK1003561A1 (en) 1998-10-30

Family

ID=23240954

Family Applications (3)

Application Number Title Priority Date Filing Date
HK98102611A HK1003561A1 (en) 1994-10-06 1998-03-27 Modafinil composition of defined particle size
HK00103669A HK1024625A1 (en) 1994-10-06 2000-06-19 Modafinil having defined particle size
HK01105376A HK1034676A1 (en) 1994-10-06 2001-08-01 Modafinil having defined particle size

Family Applications After (2)

Application Number Title Priority Date Filing Date
HK00103669A HK1024625A1 (en) 1994-10-06 2000-06-19 Modafinil having defined particle size
HK01105376A HK1034676A1 (en) 1994-10-06 2001-08-01 Modafinil having defined particle size

Country Status (34)

Country Link
US (2) US5618845A (de)
EP (3) EP0731698B1 (de)
JP (1) JP2915146B2 (de)
KR (1) KR100249360B1 (de)
AT (3) ATE400260T1 (de)
AU (1) AU703087B2 (de)
BG (1) BG62952B1 (de)
BR (1) BR9509257A (de)
CA (2) CA2382275C (de)
CZ (1) CZ291700B6 (de)
DE (3) DE69514497T2 (de)
DK (3) DK1088549T3 (de)
EE (1) EE9700082A (de)
ES (3) ES2156457T3 (de)
FI (1) FI121454B (de)
GB (1) GB2293103B (de)
GR (2) GR3033152T3 (de)
HK (3) HK1003561A1 (de)
HU (1) HU226411B1 (de)
IS (1) IS1987B (de)
LT (1) LT4303B (de)
LV (1) LV11852B (de)
MD (1) MD970143A (de)
MX (1) MX9602176A (de)
NO (1) NO318818B1 (de)
NZ (1) NZ295869A (de)
PL (1) PL181523B1 (de)
PT (3) PT966962E (de)
RO (1) RO118928B1 (de)
RU (1) RU2287987C2 (de)
SI (1) SI9520106B (de)
SK (1) SK283632B6 (de)
UA (1) UA42023C2 (de)
WO (1) WO1996011001A1 (de)

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US6821975B1 (en) 1999-08-03 2004-11-23 Lilly Icos Llc Beta-carboline drug products
UA71629C2 (en) * 1999-08-03 2004-12-15 Lilli Icos Llc Composition containing free drug particulate form of ?-carboline (variants), method for its manufacture (variants), and method for treating sexual dysfunction
US6346548B1 (en) * 1999-08-16 2002-02-12 Cephalon, Inc. Compositions including modafinil for treatment of attention deficit hyperactivity disorder and multiple sclerosis fatigue
US6455588B1 (en) 1999-08-20 2002-09-24 Cephalon, Inc. Compositions including modafinil for treatment of eating disorders and for appetite stimulation
FR2804322B1 (fr) * 2000-01-31 2002-04-19 Lafon Labor Utilisation du modafinil pour la fabrication d'un medicament destine a corriger les troubles de la vigilance associes aux myopathies
US20010034373A1 (en) * 2000-02-09 2001-10-25 Matthew Miller Low dose modafinil for enhancement of cognitive function
US6492396B2 (en) 2000-05-16 2002-12-10 Cephalon, Inc. Substituted thioacetamides
AU2001283008A1 (en) * 2000-07-27 2002-02-13 Teva Pharmaceutical Industries Ltd. Crystalline and pure modafinil, and process of preparing the same
US6489363B2 (en) 2000-10-11 2002-12-03 Cephalon, Inc. Pharmaceutical solutions of modafinil compounds
MXPA03003152A (es) * 2000-10-11 2005-07-29 Cephalon Inc Composiciones que contienen compuestos de modafinilo.
US6919378B2 (en) * 2000-10-11 2005-07-19 Cephalon, Inc. Pharmaceutical solutions of modafinil compounds
ATE417608T1 (de) * 2000-10-11 2009-01-15 Cephalon Inc Arzneizusammensetzungen enthaltend modafinilverbindungen
US7141555B2 (en) 2000-12-19 2006-11-28 Cephalon, Inc. Modafinil compound and cyclodextrin mixtures
US7704975B2 (en) * 2000-12-19 2010-04-27 Cephalon, Inc. Modafinil compound and cyclodextrin mixtures
US20080058424A1 (en) * 2002-05-23 2008-03-06 Cephalon, Inc. Novel pharmaceutical formulations of modafinil
MXPA03010705A (es) * 2001-05-25 2004-05-27 Cephalon Inc Formulaciones farmaceuticas solidas que comprenden modafinil.
US7576133B2 (en) 2002-03-11 2009-08-18 Carl Henry Lawyer Methods and compositions for nasal administration of modafinil
US7229644B2 (en) * 2002-05-23 2007-06-12 Cephalon, Inc. Pharmaceutical formulations of modafinil
US7115281B2 (en) 2002-07-08 2006-10-03 Ranbaxy Laboratories Limited Processes for the preparation of oral dosage formulations of modafinil
US20040048931A1 (en) * 2002-07-12 2004-03-11 Craig Heacock Modafinil pharmaceutical compositions
WO2004010979A1 (en) * 2002-07-25 2004-02-05 Ranbaxy Laboratories Limited Processes for the preparation of oral dosage formulations of modafinil
US6992219B2 (en) 2002-08-09 2006-01-31 Cephalon France Modafinil polymorphic forms
US20040116532A1 (en) * 2002-09-13 2004-06-17 Craig Heacock Pharmaceutical formulations of modafinil
US20040138180A1 (en) * 2002-10-03 2004-07-15 Barr Laboratories, Inc. Bisphosphonate composition and process for the preparation thereof
IL153098A0 (en) * 2002-11-26 2003-06-24 Chemagis Ltd Pharmaceutical compositions containing modafinil
CA2420180A1 (en) * 2003-02-28 2004-08-28 Bernard Charles Sherman Tablets comprising modafinil
CA2519117C (en) * 2003-03-17 2010-03-02 Neurohealing Pharmaceuticals, Inc. High potency dopaminergic treatment of neurological impairment associated with brain injury
US20040253308A1 (en) * 2003-04-29 2004-12-16 Barr Laboratories, Inc. Surface-treated modafinil particles
ES2330321T3 (es) * 2003-05-16 2009-12-09 Cephalon France Procedimiento de sintesis de modafinilo.
US7368591B2 (en) 2003-09-19 2008-05-06 Cephalon France Process for enantioselective synthesis of single enantiomers of modafinil by asymmetric oxidation
US20050137264A1 (en) * 2003-12-22 2005-06-23 Patel Ashish A. Modafinil compositions
EP2292213A1 (de) 2004-02-06 2011-03-09 Cephalon, Inc. Armodafinil Polymorph enthaltende Zusammensetzungen
US20060024370A1 (en) * 2004-07-29 2006-02-02 Cephalon France Modafinil oral lyophilizate
GT200600008A (es) * 2005-01-18 2006-08-09 Formulacion de compresion directa y proceso
CA2614777C (en) * 2005-07-21 2012-04-17 Neurohealing Pharmaceuticals, Inc. Rapid onset and short term modafinil compositions and methods of use thereof
US9034381B2 (en) * 2005-11-10 2015-05-19 Alphapharm Pty Ltd Process to control particle size
KR20090031618A (ko) * 2006-07-12 2009-03-26 엘란 코포레이션, 피엘씨 나노입자형 모다피닐 제제
CA2660565C (en) * 2006-08-14 2012-10-09 Neurohealing Pharmaceuticals, Inc. Modafinil-based treatment for premature ejaculation
US20080181966A1 (en) * 2006-10-18 2008-07-31 Cephalon, Inc. Modafinil pharmaceutical compositions
WO2008074097A1 (en) 2006-12-21 2008-06-26 Alphapharm Pty Ltd Pharmaceutical compound and composition
US8173169B2 (en) * 2007-07-11 2012-05-08 Hikma Pharmaceuticals Formulation and process for the preparation of modafinil
US20090325999A1 (en) * 2008-06-27 2009-12-31 Jie Du Personalized pharmaceutical kits, packaging and compositions for the treatment of allergic conditions
CA2767560A1 (en) * 2008-07-25 2010-01-28 Alphapharm Pty Ltd Atovaquone with a particle size diameter range (d90) of greater than 3um to about 10um
US20100036164A1 (en) * 2008-08-06 2010-02-11 Srinivas Areveli Preparation of armodafinil form i
EP2238973A1 (de) 2009-04-07 2010-10-13 Cephalon France Lyophilisierte Präparate von Proteasominhibitoren
FR2987267B1 (fr) * 2012-02-28 2015-01-16 Debregeas Et Associes Pharma Application du modafinil dans le traitement de substitution des cacainomanes
FR2987266B1 (fr) 2012-02-28 2014-12-19 Debregeas Et Associes Pharma Procede d'obtention d'une composition pharmaceutique a base de modafinil, composition pharmaceutique ainsi obtenue et son application
FR2987265B1 (fr) * 2012-02-28 2014-02-28 Debregeas Et Associes Pharma Composition pharmaceutique sous forme de sirop a base de modafinil, son procede de fabrication et son application
US10058542B1 (en) 2014-09-12 2018-08-28 Thioredoxin Systems Ab Composition comprising selenazol or thiazolone derivatives and silver and method of treatment therewith

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Also Published As

Publication number Publication date
RU2287987C2 (ru) 2006-11-27
DE69514497D1 (de) 2000-02-17
EP0966962B1 (de) 2001-02-21
CA2201967A1 (en) 1996-04-18
ES2308960T3 (es) 2008-12-16
FI121454B (fi) 2010-11-30
PT731698E (pt) 2000-05-31
PL319480A1 (en) 1997-08-04
LT97060A (en) 1997-10-27
ATE188607T1 (de) 2000-01-15
MD970143A (ro) 1998-12-31
EE9700082A (et) 1997-10-15
HUT77778A (hu) 1998-08-28
LV11852B (en) 1998-03-20
PT1088549E (pt) 2008-09-23
NO971541D0 (no) 1997-04-04
GR3033152T3 (en) 2000-08-31
CZ103297A3 (en) 1997-09-17
CA2382275A1 (en) 1996-04-18
BG62952B1 (bg) 2000-12-29
PL181523B1 (en) 2001-08-31
ATE199216T1 (de) 2001-03-15
MX9602176A (es) 1997-05-31
ES2142499T3 (es) 2000-04-16
NZ295869A (en) 1998-02-26
GB9524328D0 (en) 1996-01-31
SK44597A3 (en) 1997-09-10
EP0731698A1 (de) 1996-09-18
US5618845A (en) 1997-04-08
FI971417A0 (fi) 1997-04-04
WO1996011001A1 (en) 1996-04-18
ATE400260T1 (de) 2008-07-15
EP0966962A1 (de) 1999-12-29
FI971417A (fi) 1997-04-04
HK1034676A1 (en) 2001-11-02
USRE37516E1 (en) 2002-01-15
DE69520161T2 (de) 2001-08-02
HK1024625A1 (en) 2000-10-20
SK283632B6 (sk) 2003-11-04
SI9520106A (sl) 1998-02-28
GB2293103B (en) 1997-05-07
DK0966962T3 (da) 2001-03-19
EP0731698B1 (de) 2000-01-12
ES2156457T3 (es) 2001-06-16
LT4303B (lt) 1998-03-25
UA42023C2 (uk) 2001-10-15
KR100249360B1 (ko) 2000-04-01
EP1088549A1 (de) 2001-04-04
DK1088549T3 (da) 2008-11-17
IS1987B (is) 2005-02-15
PT966962E (pt) 2001-06-29
GB2293103A (en) 1996-03-20
JP2915146B2 (ja) 1999-07-05
GR3035451T3 (en) 2001-05-31
DE69535786D1 (de) 2008-08-21
NO971541L (no) 1997-06-04
NO318818B1 (no) 2005-05-09
DK0731698T3 (da) 2000-05-08
CA2382275C (en) 2003-12-16
SI9520106B (sl) 2003-12-31
DE69514497T2 (de) 2000-08-10
AU703087B2 (en) 1999-03-18
AU3951495A (en) 1996-05-02
CZ291700B6 (cs) 2003-05-14
IS4451A (is) 1997-03-24
CA2201967C (en) 2002-12-10
EP1088549B1 (de) 2008-07-09
LV11852A (lv) 1997-10-20
JPH09511754A (ja) 1997-11-25
BG101389A (en) 1997-12-30
BR9509257A (pt) 1998-07-07
DE69520161D1 (de) 2001-03-29
RO118928B1 (ro) 2004-01-30
HU226411B1 (en) 2008-11-28

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Effective date: 20151003