GT201400009A - 4-imidazopiridazin-1-il-benzamidas y 4-imidazotriazin-1-il-benzamidas como inhibidores de btk - Google Patents

4-imidazopiridazin-1-il-benzamidas y 4-imidazotriazin-1-il-benzamidas como inhibidores de btk

Info

Publication number
GT201400009A
GT201400009A GT201400009A GT201400009A GT201400009A GT 201400009 A GT201400009 A GT 201400009A GT 201400009 A GT201400009 A GT 201400009A GT 201400009 A GT201400009 A GT 201400009A GT 201400009 A GT201400009 A GT 201400009A
Authority
GT
Guatemala
Prior art keywords
benzamidas
imidazotriazin
imidazopiridazin
btk inhibitors
members
Prior art date
Application number
GT201400009A
Other languages
English (en)
Spanish (es)
Inventor
Tjeerd A Barf
Christiaan Gerardus Johannes Maria Jans
De Adrianus Petrus Antonius Man
Arthur A Oubrie
Hans C A Raaijmakers
Johannes Bernardus Maria Rewinkel
Jan-Gerard Sterrenburg
Jacobus C H M Wijkmans
Original Assignee
Merck Sharp & Dohme
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=47557677&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=GT201400009(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Merck Sharp & Dohme filed Critical Merck Sharp & Dohme
Publication of GT201400009A publication Critical patent/GT201400009A/es

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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4985—Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
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  • Communicable Diseases (AREA)
  • Pulmonology (AREA)
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  • Urology & Nephrology (AREA)
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  • Pain & Pain Management (AREA)
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  • Obesity (AREA)
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  • Gastroenterology & Hepatology (AREA)
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  • Transplantation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
GT201400009A 2011-07-19 2014-01-17 4-imidazopiridazin-1-il-benzamidas y 4-imidazotriazin-1-il-benzamidas como inhibidores de btk GT201400009A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161509397P 2011-07-19 2011-07-19
EP11174578 2011-07-19

Publications (1)

Publication Number Publication Date
GT201400009A true GT201400009A (es) 2017-09-28

Family

ID=47557677

Family Applications (1)

Application Number Title Priority Date Filing Date
GT201400009A GT201400009A (es) 2011-07-19 2014-01-17 4-imidazopiridazin-1-il-benzamidas y 4-imidazotriazin-1-il-benzamidas como inhibidores de btk

Country Status (38)

Country Link
US (7) US9290504B2 (en:Method)
EP (4) EP2734522B1 (en:Method)
JP (6) JP5826931B2 (en:Method)
KR (2) KR101802689B1 (en:Method)
CN (2) CN103889987B (en:Method)
AU (4) AU2012285987C1 (en:Method)
BR (1) BR112014001255B1 (en:Method)
CA (1) CA2841886C (en:Method)
CL (1) CL2014000130A1 (en:Method)
CO (1) CO6940411A2 (en:Method)
CR (1) CR20140030A (en:Method)
CY (2) CY2021010I1 (en:Method)
DK (2) DK3689878T3 (en:Method)
DO (1) DOP2014000008A (en:Method)
EA (2) EA037644B1 (en:Method)
EC (1) ECSP14013217A (en:Method)
ES (3) ES2950569T3 (en:Method)
GT (1) GT201400009A (en:Method)
HR (2) HRP20212021T1 (en:Method)
HU (3) HUE056249T2 (en:Method)
IL (3) IL230511B (en:Method)
IN (1) IN2014CN00408A (en:Method)
LT (1) LT2734522T (en:Method)
MA (1) MA35348B1 (en:Method)
MX (1) MX342983B (en:Method)
MY (1) MY192354A (en:Method)
PE (1) PE20141681A1 (en:Method)
PH (2) PH12014500148A1 (en:Method)
PL (2) PL2734522T3 (en:Method)
PT (1) PT3689878T (en:Method)
RS (2) RS58177B1 (en:Method)
SG (1) SG10201605913VA (en:Method)
SI (2) SI2734522T1 (en:Method)
SM (2) SMT201900029T1 (en:Method)
TN (1) TN2014000027A1 (en:Method)
UA (1) UA115312C2 (en:Method)
WO (1) WO2013010868A1 (en:Method)
ZA (1) ZA202109164B (en:Method)

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US9376438B2 (en) 2011-05-17 2016-06-28 Principia Biopharma, Inc. Pyrazolopyrimidine derivatives as tyrosine kinase inhibitors
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US9138436B2 (en) 2011-07-13 2015-09-22 Pharmacyclics Llc Inhibitors of Bruton's tyrosine kinase
EP2548877A1 (en) 2011-07-19 2013-01-23 MSD Oss B.V. 4-(5-Membered fused pyridinyl)benzamides as BTK-inhibitors
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EP2877598A1 (en) 2012-07-24 2015-06-03 Pharmacyclics, Inc. Mutations associated with resistance to inhibitors of bruton's tyrosine kinase (btk)
ES2731833T3 (es) 2012-09-10 2019-11-19 Principia Biopharma Inc Compuestos pirazolopirimidínicos comos inhibidores de cinasas
CA2886240A1 (en) 2012-09-26 2014-04-03 The Regents Of The University Of California Modulation of ire1
CA2887465A1 (en) * 2012-10-04 2014-04-10 University Of Utah Research Foundation Substituted n-(3-(pyrimidin-4-yl)phenyl)acrylamide analogs as tyrosine receptor kinase btk inhibitors
AU2013337717B2 (en) 2012-11-01 2018-10-25 Infinity Pharmaceuticals, Inc. Treatment of cancers using PI3 kinase isoform modulators
WO2014113942A1 (en) * 2013-01-23 2014-07-31 Merck Sharp & Dohme Corp. Btk inhibitors
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US8957080B2 (en) 2013-04-09 2015-02-17 Principia Biopharma Inc. Tyrosine kinase inhibitors
CN105682658B (zh) * 2013-05-30 2022-04-05 无限药品公司 使用pi3激酶亚型调节剂的癌症疗法
RU2712220C2 (ru) 2013-07-31 2020-01-27 Мерк Патент Гмбх Пиридины, пиримидины и пиразины в качестве ингибиторов тирозинкиназы брутона и их применение
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