GR3017940T3 - Crystalline salt of 4-(di-n-propyl)amino-6-aminocarbonyl-1,3,4,5-tetrahydrobenz[cd]indole. - Google Patents

Crystalline salt of 4-(di-n-propyl)amino-6-aminocarbonyl-1,3,4,5-tetrahydrobenz[cd]indole.

Info

Publication number
GR3017940T3
GR3017940T3 GR950403048T GR950403048T GR3017940T3 GR 3017940 T3 GR3017940 T3 GR 3017940T3 GR 950403048 T GR950403048 T GR 950403048T GR 950403048 T GR950403048 T GR 950403048T GR 3017940 T3 GR3017940 T3 GR 3017940T3
Authority
GR
Greece
Prior art keywords
tetrahydrobenz
aminocarbonyl
propyl
amino
indole
Prior art date
Application number
GR950403048T
Other languages
Greek (el)
English (en)
Inventor
Thomas Joseph Kress
David Lee Varie
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of GR3017940T3 publication Critical patent/GR3017940T3/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56—Ring systems containing three or more rings
    • C07D209/80—[b, c]- or [b, d]-condensed
    • C07D209/90—Benzo [c, d] indoles; Hydrogenated benzo [c, d] indoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/32—Alcohol-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Psychiatry (AREA)
  • Addiction (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Hospice & Palliative Care (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Indole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
GR950403048T 1990-02-26 1995-11-01 Crystalline salt of 4-(di-n-propyl)amino-6-aminocarbonyl-1,3,4,5-tetrahydrobenz[cd]indole. GR3017940T3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US48518590A 1990-02-26 1990-02-26

Publications (1)

Publication Number Publication Date
GR3017940T3 true GR3017940T3 (en) 1996-02-29

Family

ID=23927224

Family Applications (1)

Application Number Title Priority Date Filing Date
GR950403048T GR3017940T3 (en) 1990-02-26 1995-11-01 Crystalline salt of 4-(di-n-propyl)amino-6-aminocarbonyl-1,3,4,5-tetrahydrobenz[cd]indole.

Country Status (28)

Country Link
US (1) US5397799A (en:Method)
EP (1) EP0444852B1 (en:Method)
JP (1) JP3157007B2 (en:Method)
KR (1) KR100208114B1 (en:Method)
CN (1) CN1027503C (en:Method)
AT (1) ATE126506T1 (en:Method)
AU (1) AU629453B2 (en:Method)
BR (1) BR9100767A (en:Method)
CA (1) CA2037099C (en:Method)
CY (1) CY1887A (en:Method)
DE (1) DE69112099T2 (en:Method)
DK (1) DK0444852T3 (en:Method)
ES (1) ES2077796T3 (en:Method)
FI (1) FI95464C (en:Method)
GR (1) GR3017940T3 (en:Method)
HK (1) HK175495A (en:Method)
HU (1) HU217118B (en:Method)
IE (1) IE67801B1 (en:Method)
IL (1) IL97306A (en:Method)
LV (1) LV10251B (en:Method)
NO (1) NO174149C (en:Method)
NZ (1) NZ237181A (en:Method)
PT (1) PT96852B (en:Method)
RU (2) RU2034837C1 (en:Method)
SG (1) SG69975A1 (en:Method)
TW (1) TW219933B (en:Method)
YU (1) YU47594B (en:Method)
ZA (1) ZA911258B (en:Method)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5302612A (en) * 1990-02-26 1994-04-12 Eli Lilly And Company 6-substituted-hexahydrobenz[cd]indoles
IL97308A (en) * 1990-02-26 1996-10-31 Lilly Co Eli 6-Substituted-hexahydrobenz (cd) indoles process for their preparation and pharmaceutical compositions containing them
IL97309A (en) * 1990-02-26 1996-11-14 Lilly Co Eli Intermediates for hexahydrobenz Úcd¾ indoles and process for the preparation of pure enantiomers thereof
US5364856A (en) * 1991-03-28 1994-11-15 Eli Lilly And Company 6-heterocyclic-4-amino-1,3,4,5-tetrahydrobenz[CD]indoles
US5643934A (en) * 1991-03-28 1997-07-01 Eli Lilly And Company 6-heterocyclic-4-amino-1,2,2a,3,4,5-hexahydrobenz [CD]indoles
TW248556B (en:Method) * 1993-01-18 1995-06-01 Takeda Pharm Industry Co
UA53205C2 (en) * 2002-04-03 2006-06-15 Pharmatech Close Joint Stock C Antidepressant formulation and method for its manufacture
US7588924B2 (en) 2006-03-07 2009-09-15 Procter & Gamble Company Crystal of hypoxia inducible factor 1 alpha prolyl hydroxylase
MX2009000286A (es) * 2006-06-26 2009-03-20 Procter & Gamble Inhibidores de prolil hidroxilasa y metodos de uso.
PT2649998E (pt) 2009-11-06 2015-04-21 Aerpio Therapeutics Inc Bidores da prolil-hidroxilase
US8865748B2 (en) 2011-06-06 2014-10-21 Akebia Therapeutics Inc. Compounds and compositions for stabilizing hypoxia inducible factor-2 alpha as a method for treating cancer
NO2686520T3 (en:Method) 2011-06-06 2018-03-17
PE20201496A1 (es) 2013-06-13 2020-12-29 Akebia Therapeutics Inc Composiciones y metodos para tratar anemia
PH12021551124A1 (en) 2013-11-15 2024-04-29 Akebia Therapeutics Inc Solid forms of {[5-(3-chlorophenyl)-3-hydroxypyridine-2-carbonyl]amino}acetic acid, compositions, and uses thereof
TW201632504A (zh) 2015-01-23 2016-09-16 阿克比治療有限公司 ２－（５－（３－氟苯基）－３－羥吡啶醯胺基）乙酸之固體形式、其組合物及其用途
EA036920B1 (ru) 2015-04-01 2021-01-15 Экебиа Терапьютикс, Инк. Композиции и способы для лечения анемии
KR20210006967A (ko) 2018-05-09 2021-01-19 아케비아 테라퓨틱스 인코포레이티드 2-[[5-(3-클로로페닐)-3-하이드록시피리딘-2-카르보닐]아미노]아세트산을 제조하는 방법
US11524939B2 (en) 2019-11-13 2022-12-13 Akebia Therapeutics, Inc. Solid forms of {[5-(3-chlorophenyl)-3-hydroxypyridine-2-carbonyl]amino} acetic acid

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4110339A (en) * 1977-11-25 1978-08-29 Eli Lilly And Company 4-(Di-n-propyl)amino-1,3,4,5-tetrahydrobenz[cd]indole
US4576959A (en) * 1984-02-06 1986-03-18 Eli Lilly And Company 6-Substituted-4-dialkylaminotetrahydrobenz[c,d]indoles
US4745126A (en) * 1987-03-12 1988-05-17 Eli Lilly And Company Method of treating anxiety with tetrahydrobenz[c,d]indole-6-carboxamides
DE3809155A1 (de) * 1988-03-18 1989-09-28 Bayer Ag 1,3,4,5-tetrahydrobenz-(c,d)-indole
US5204340A (en) * 1989-04-11 1993-04-20 Eli Lilly And Company Tetrahydrobenz(c,d)indole serotonin agonists
US5229409A (en) * 1990-08-15 1993-07-20 Eli Lilly And Company 6-substituted-tetrahydrobenz[cd]indoles

Also Published As

Publication number Publication date
PT96852B (pt) 1998-07-31
SG69975A1 (en) 2000-01-25
IE910625A1 (en) 1991-08-28
YU32791A (sh) 1994-01-20
FI95464B (fi) 1995-10-31
HUT56542A (en) 1991-09-30
DK0444852T3 (da) 1995-12-11
RU2034837C1 (ru) 1995-05-10
AU629453B2 (en) 1992-10-01
HU217118B (hu) 1999-11-29
CY1887A (en) 1996-04-05
NZ237181A (en) 1992-06-25
EP0444852B1 (en) 1995-08-16
CN1054589A (zh) 1991-09-18
AU7197191A (en) 1991-08-29
ZA911258B (en) 1992-10-28
LV10251B (en) 1995-04-20
IL97306A (en) 1996-10-16
ATE126506T1 (de) 1995-09-15
FI95464C (fi) 1996-02-12
NO910735L (no) 1991-08-27
NO174149C (no) 1994-03-23
NO174149B (no) 1993-12-13
NO910735D0 (no) 1991-02-25
DE69112099T2 (de) 1996-02-08
LV10251A (lv) 1994-10-20
CA2037099A1 (en) 1991-08-27
BR9100767A (pt) 1991-10-29
KR910021375A (ko) 1991-12-20
US5397799A (en) 1995-03-14
JP3157007B2 (ja) 2001-04-16
DE69112099D1 (de) 1995-09-21
HK175495A (en) 1995-11-24
KR100208114B1 (ko) 1999-07-15
IE67801B1 (en) 1996-05-01
ES2077796T3 (es) 1995-12-01
YU47594B (sh) 1995-10-24
EP0444852A2 (en) 1991-09-04
FI910895L (fi) 1991-08-27
PT96852A (pt) 1991-10-31
IL97306A0 (en) 1992-05-25
JPH04217662A (ja) 1992-08-07
CN1027503C (zh) 1995-01-25
CA2037099C (en) 2001-09-11
TW219933B (en:Method) 1994-02-01
FI910895A0 (fi) 1991-02-25
RU2083561C1 (ru) 1997-07-10
EP0444852A3 (en) 1992-02-19

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