RU92004575A - Кристаллическая соль 4-(ди-н-пропил) амино-6-аминокарбонил-1,3,4,5-тетрагидробенз (cd) индола и ее 4p и 4s-изомеры - Google Patents

Кристаллическая соль 4-(ди-н-пропил) амино-6-аминокарбонил-1,3,4,5-тетрагидробенз (cd) индола и ее 4p и 4s-изомеры

Info

Publication number
RU92004575A
RU92004575A RU92004575/04A RU92004575A RU92004575A RU 92004575 A RU92004575 A RU 92004575A RU 92004575/04 A RU92004575/04 A RU 92004575/04A RU 92004575 A RU92004575 A RU 92004575A RU 92004575 A RU92004575 A RU 92004575A
Authority
RU
Russia
Prior art keywords
tetrahydrobenz
propyl
amino
aminocarbonil
isomeres
Prior art date
Application number
RU92004575/04A
Other languages
English (en)
Other versions
RU2083561C1 (ru
Inventor
Дисозеф Кресс Томас
Ли Вари Дэвид
Original Assignee
Эли Лилли Энд Компани
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Эли Лилли Энд Компани filed Critical Эли Лилли Энд Компани
Publication of RU92004575A publication Critical patent/RU92004575A/ru
Application granted granted Critical
Publication of RU2083561C1 publication Critical patent/RU2083561C1/ru

Links

Claims (1)

  1. Предлагается метод получения и применение гиппурата 4-(ди-н-пропил)амино-6-аминокарбонил-1,3,4,5-тетрагидробенз[cd]индола.
RU9292004575A 1990-02-26 1992-12-03 Гиппурат 4-(ди-н-пропил)амино-6-аминокарбонил-1,3,4,5-тетрагидробенз [cd] индола и его 4r- и 4s-изомеры RU2083561C1 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US48518590A 1990-02-26 1990-02-26
US485.185 1990-02-26
US485185 1990-02-26

Related Parent Applications (2)

Application Number Title Priority Date Filing Date
RU107654 Addition
RU4894699 Division

Publications (2)

Publication Number Publication Date
RU92004575A true RU92004575A (ru) 1995-09-27
RU2083561C1 RU2083561C1 (ru) 1997-07-10

Family

ID=23927224

Family Applications (2)

Application Number Title Priority Date Filing Date
SU914894699A RU2034837C1 (ru) 1990-02-26 1991-02-25 Способ получения гиппурата 4-(ди-н-пропил)амино-6-аминокарбонил-1,3,4,5-тетрагидробенз(cd)индола
RU9292004575A RU2083561C1 (ru) 1990-02-26 1992-12-03 Гиппурат 4-(ди-н-пропил)амино-6-аминокарбонил-1,3,4,5-тетрагидробенз [cd] индола и его 4r- и 4s-изомеры

Family Applications Before (1)

Application Number Title Priority Date Filing Date
SU914894699A RU2034837C1 (ru) 1990-02-26 1991-02-25 Способ получения гиппурата 4-(ди-н-пропил)амино-6-аминокарбонил-1,3,4,5-тетрагидробенз(cd)индола

Country Status (28)

Country Link
US (1) US5397799A (ru)
EP (1) EP0444852B1 (ru)
JP (1) JP3157007B2 (ru)
KR (1) KR100208114B1 (ru)
CN (1) CN1027503C (ru)
AT (1) ATE126506T1 (ru)
AU (1) AU629453B2 (ru)
BR (1) BR9100767A (ru)
CA (1) CA2037099C (ru)
CY (1) CY1887A (ru)
DE (1) DE69112099T2 (ru)
DK (1) DK0444852T3 (ru)
ES (1) ES2077796T3 (ru)
FI (1) FI95464C (ru)
GR (1) GR3017940T3 (ru)
HK (1) HK175495A (ru)
HU (1) HU217118B (ru)
IE (1) IE67801B1 (ru)
IL (1) IL97306A (ru)
LV (1) LV10251B (ru)
NO (1) NO174149C (ru)
NZ (1) NZ237181A (ru)
PT (1) PT96852B (ru)
RU (2) RU2034837C1 (ru)
SG (1) SG69975A1 (ru)
TW (1) TW219933B (ru)
YU (1) YU47594B (ru)
ZA (1) ZA911258B (ru)

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US5302612A (en) * 1990-02-26 1994-04-12 Eli Lilly And Company 6-substituted-hexahydrobenz[cd]indoles
IL97308A (en) * 1990-02-26 1996-10-31 Lilly Co Eli Xahydrobenz [DC] Induced indoles in position 6, their preparation process and pharmaceutical preparations containing them
IL97309A (en) * 1990-02-26 1996-11-14 Lilly Co Eli Intermediates for hexahydrobenz] [DC indoles and a process for making their pure enantiomers
US5364856A (en) * 1991-03-28 1994-11-15 Eli Lilly And Company 6-heterocyclic-4-amino-1,3,4,5-tetrahydrobenz[CD]indoles
US5665744A (en) * 1991-03-28 1997-09-09 Eli Lilly And Company 6-heterocyclic-4-amino-1,2,2A,3,4,5-hexahydrobenzn [cd] indoles
TW248556B (ru) * 1993-01-18 1995-06-01 Takeda Pharm Industry Co
US7588924B2 (en) 2006-03-07 2009-09-15 Procter & Gamble Company Crystal of hypoxia inducible factor 1 alpha prolyl hydroxylase
EP3026044B8 (en) 2006-06-26 2018-12-19 Akebia Therapeutics, Inc. Prolyl hydroxylase inhibitors and methods of use
EP2496084B1 (en) 2009-11-06 2015-06-10 Aerpio Therapeutics Inc. Compositions and methods for treating colitis
CA2837560C (en) 2011-06-06 2017-02-14 Akebia Therapeutics Inc. Compounds and compositions for stabilizing hypoxia inducible factor-2 alpha as a method for treating cancer
NO2686520T3 (ru) 2011-06-06 2018-03-17
CN114404414A (zh) 2013-06-13 2022-04-29 阿克比治疗有限公司 用于治疗贫血症的组合物和方法
TWI665190B (zh) 2013-11-15 2019-07-11 阿克比治療有限公司 ｛［５－（３－氯苯基）－３－羥基吡啶－２－羰基］胺基｝乙酸之固體型式，其組合物及用途
US10150734B2 (en) 2015-01-23 2018-12-11 Akebia Therapeutics, Inc. Solid forms of 2-(5-(3-fluorophenyl)-3-hydroxypicolinamido)acetic acid, compositions, and uses thereof
BR112017021097B1 (pt) 2015-04-01 2024-01-02 Akebia Therapeutics, Inc Formulação de dosagem oral e seu uso
TW202406895A (zh) 2018-05-09 2024-02-16 美商阿克比治療有限公司 用於製備2-[[5-(3-氯苯基)-3-羥基吡啶-2-羰基]胺基]乙酸之方法
US11524939B2 (en) 2019-11-13 2022-12-13 Akebia Therapeutics, Inc. Solid forms of {[5-(3-chlorophenyl)-3-hydroxypyridine-2-carbonyl]amino} acetic acid

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4110339A (en) * 1977-11-25 1978-08-29 Eli Lilly And Company 4-(Di-n-propyl)amino-1,3,4,5-tetrahydrobenz[cd]indole
US4576959A (en) * 1984-02-06 1986-03-18 Eli Lilly And Company 6-Substituted-4-dialkylaminotetrahydrobenz[c,d]indoles
US4745126A (en) * 1987-03-12 1988-05-17 Eli Lilly And Company Method of treating anxiety with tetrahydrobenz[c,d]indole-6-carboxamides
DE3809155A1 (de) * 1988-03-18 1989-09-28 Bayer Ag 1,3,4,5-tetrahydrobenz-(c,d)-indole
US5204340A (en) * 1989-04-11 1993-04-20 Eli Lilly And Company Tetrahydrobenz(c,d)indole serotonin agonists
US5229409A (en) * 1990-08-15 1993-07-20 Eli Lilly And Company 6-substituted-tetrahydrobenz[cd]indoles

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