GB1455552A - Pharmaceutical composition for topical administration - Google Patents
Pharmaceutical composition for topical administrationInfo
- Publication number
- GB1455552A GB1455552A GB955575A GB955575A GB1455552A GB 1455552 A GB1455552 A GB 1455552A GB 955575 A GB955575 A GB 955575A GB 955575 A GB955575 A GB 955575A GB 1455552 A GB1455552 A GB 1455552A
- Authority
- GB
- United Kingdom
- Prior art keywords
- pharmaceutical composition
- topical administration
- addition
- neomycin
- polyglycol
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 3
- 238000011200 topical administration Methods 0.000 title abstract 3
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 abstract 3
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 abstract 3
- 229930193140 Neomycin Natural products 0.000 abstract 3
- 229960004927 neomycin Drugs 0.000 abstract 3
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 2
- KFZMGEQAYNKOFK-UHFFFAOYSA-N Isopropanol Chemical compound CC(C)O KFZMGEQAYNKOFK-UHFFFAOYSA-N 0.000 abstract 2
- 239000002202 Polyethylene glycol Substances 0.000 abstract 2
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 abstract 2
- 229910001514 alkali metal chloride Inorganic materials 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- 229920001223 polyethylene glycol Polymers 0.000 abstract 2
- 229920000151 polyglycol Polymers 0.000 abstract 2
- 239000010695 polyglycol Substances 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- PUPZLCDOIYMWBV-UHFFFAOYSA-N (+/-)-1,3-Butanediol Chemical compound CC(O)CCO PUPZLCDOIYMWBV-UHFFFAOYSA-N 0.000 abstract 1
- 229920002153 Hydroxypropyl cellulose Polymers 0.000 abstract 1
- DWAQJAXMDSEUJJ-UHFFFAOYSA-M Sodium bisulfite Chemical compound [Na+].OS([O-])=O DWAQJAXMDSEUJJ-UHFFFAOYSA-M 0.000 abstract 1
- QAOWNCQODCNURD-UHFFFAOYSA-L Sulfate Chemical compound [O-]S([O-])(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-L 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 230000001476 alcoholic effect Effects 0.000 abstract 1
- 230000000844 anti-bacterial effect Effects 0.000 abstract 1
- 230000003110 anti-inflammatory effect Effects 0.000 abstract 1
- 239000003963 antioxidant agent Substances 0.000 abstract 1
- 230000003078 antioxidant effect Effects 0.000 abstract 1
- 235000006708 antioxidants Nutrition 0.000 abstract 1
- 239000007864 aqueous solution Substances 0.000 abstract 1
- 229960000870 betamethasone benzoate Drugs 0.000 abstract 1
- SOQJPQZCPBDOMF-YCUXZELOSA-N betamethasone benzoate Chemical compound O([C@]1([C@@]2(C)C[C@H](O)[C@]3(F)[C@@]4(C)C=CC(=O)C=C4CC[C@H]3[C@@H]2C[C@@H]1C)C(=O)CO)C(=O)C1=CC=CC=C1 SOQJPQZCPBDOMF-YCUXZELOSA-N 0.000 abstract 1
- 239000002738 chelating agent Substances 0.000 abstract 1
- 229960001347 fluocinolone acetonide Drugs 0.000 abstract 1
- FEBLZLNTKCEFIT-VSXGLTOVSA-N fluocinolone acetonide Chemical compound C1([C@@H](F)C2)=CC(=O)C=C[C@]1(C)[C@]1(F)[C@@H]2[C@@H]2C[C@H]3OC(C)(C)O[C@@]3(C(=O)CO)[C@@]2(C)C[C@@H]1O FEBLZLNTKCEFIT-VSXGLTOVSA-N 0.000 abstract 1
- 239000001863 hydroxypropyl cellulose Substances 0.000 abstract 1
- 235000010977 hydroxypropyl cellulose Nutrition 0.000 abstract 1
- 239000001866 hydroxypropyl methyl cellulose Substances 0.000 abstract 1
- 229920003088 hydroxypropyl methyl cellulose Polymers 0.000 abstract 1
- 235000010979 hydroxypropyl methyl cellulose Nutrition 0.000 abstract 1
- UFVKGYZPFZQRLF-UHFFFAOYSA-N hydroxypropyl methyl cellulose Chemical compound OC1C(O)C(OC)OC(CO)C1OC1C(O)C(O)C(OC2C(C(O)C(OC3C(C(O)C(O)C(CO)O3)O)C(CO)O2)O)C(CO)O1 UFVKGYZPFZQRLF-UHFFFAOYSA-N 0.000 abstract 1
- 229920001451 polypropylene glycol Polymers 0.000 abstract 1
- 239000011780 sodium chloride Substances 0.000 abstract 1
- 239000004289 sodium hydrogen sulphite Substances 0.000 abstract 1
- 235000010267 sodium hydrogen sulphite Nutrition 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
- 150000003431 steroids Chemical class 0.000 abstract 1
- 229910021653 sulphate ion Inorganic materials 0.000 abstract 1
- 239000002562 thickening agent Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/38—Cellulose; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Inorganic Chemistry (AREA)
- Dermatology (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US46025474A | 1974-04-11 | 1974-04-11 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1455552A true GB1455552A (en) | 1976-11-17 |
Family
ID=23827960
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB955575A Expired GB1455552A (en) | 1974-04-11 | 1975-03-21 | Pharmaceutical composition for topical administration |
Country Status (7)
| Country | Link |
|---|---|
| JP (1) | JPS535729B2 (enExample) |
| AU (1) | AU7776275A (enExample) |
| CA (1) | CA1049409A (enExample) |
| DE (2) | DE2504615C3 (enExample) |
| DK (1) | DK143537C (enExample) |
| FR (1) | FR2267107B1 (enExample) |
| GB (1) | GB1455552A (enExample) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2140298A (en) * | 1983-05-13 | 1984-11-28 | Schering Corp | Topical betamethasone dipropionate composition |
| WO2002022139A1 (en) * | 2000-09-14 | 2002-03-21 | Robert Theiler | Intraarticular agent for the treatment of osteoarthritis |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS59501159A (ja) * | 1982-06-24 | 1984-07-05 | スミス、ロバ−ト・アラン | 薬用ゲル組成物 |
| DE3333240A1 (de) * | 1983-09-12 | 1985-03-28 | Schering AG, 1000 Berlin und 4709 Bergkamen | Mittel zur transdermalen applikation von arzneimittelwirkstoffen |
| AU592065B2 (en) * | 1984-10-09 | 1990-01-04 | Dow Chemical Company, The | Sustained release dosage form based on highly plasticized cellulose ether gels |
| FR2588189B1 (fr) * | 1985-10-03 | 1988-12-02 | Merck Sharp & Dohme | Composition pharmaceutique de type a transition de phase liquide-gel |
| DE3614095A1 (de) * | 1986-04-25 | 1987-10-29 | Goedecke Ag | Oxyalkylcellulose enthaltende gelzubereitung |
| ES2078256T3 (es) * | 1990-04-05 | 1995-12-16 | Knoll Ag | Formula farmaceutica para uso topico que contiene diclofenaco sodico. |
| ES2391721T3 (es) * | 2010-03-01 | 2012-11-29 | Laboratorios Salvat, S.A. | Disoluciones acuosas transparentes de acetónido de fluocinolona para el tratamiento de la infamación de oído |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1017746B (de) * | 1954-02-09 | 1957-10-17 | Upjohn Co | Verfahren zur Herstellung frei fliessender, nicht absetzender therapeutisch wirksamer Suspensionen |
| US3485915A (en) * | 1966-04-22 | 1969-12-23 | Revlon | Thickened hydroxypropyl cellulose compositions |
| DE2015300A1 (de) * | 1969-04-01 | 1970-10-29 | Syntex Corp., Panania;PM | örtliche, entzündungshemmende Präparate und Verfahren zu ihrer Verwendung |
| DK135267A (enExample) * | 1971-02-25 |
-
1975
- 1975-01-30 AU AU77762/75A patent/AU7776275A/en not_active Expired
- 1975-02-04 DE DE19752504615 patent/DE2504615C3/de not_active Expired
- 1975-03-20 JP JP3426675A patent/JPS535729B2/ja not_active Expired
- 1975-03-21 GB GB955575A patent/GB1455552A/en not_active Expired
- 1975-04-07 FR FR7510763A patent/FR2267107B1/fr not_active Expired
- 1975-04-07 DK DK147575A patent/DK143537C/da not_active IP Right Cessation
- 1975-04-10 DE DE19752515594 patent/DE2515594C3/de not_active Expired
- 1975-04-10 CA CA224,302A patent/CA1049409A/en not_active Expired
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2140298A (en) * | 1983-05-13 | 1984-11-28 | Schering Corp | Topical betamethasone dipropionate composition |
| WO2002022139A1 (en) * | 2000-09-14 | 2002-03-21 | Robert Theiler | Intraarticular agent for the treatment of osteoarthritis |
Also Published As
| Publication number | Publication date |
|---|---|
| FR2267107A1 (enExample) | 1975-11-07 |
| AU7776275A (en) | 1976-08-05 |
| JPS50132122A (enExample) | 1975-10-20 |
| CA1049409A (en) | 1979-02-27 |
| DK147575A (enExample) | 1975-10-12 |
| JPS535729B2 (enExample) | 1978-03-01 |
| DE2515594B2 (de) | 1978-12-07 |
| DE2504615C3 (de) | 1980-10-02 |
| DK143537B (da) | 1981-09-07 |
| DE2504615A1 (de) | 1975-10-16 |
| DK143537C (da) | 1982-02-01 |
| FR2267107B1 (enExample) | 1978-07-28 |
| DE2504615B2 (de) | 1977-07-14 |
| DE2515594C3 (de) | 1982-06-03 |
| DE2515594A1 (de) | 1975-10-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed | ||
| PCNP | Patent ceased through non-payment of renewal fee |