GB1446352A - Pharmaceutical compositions - Google Patents

Pharmaceutical compositions

Info

Publication number
GB1446352A
GB1446352A GB4039973A GB4039973A GB1446352A GB 1446352 A GB1446352 A GB 1446352A GB 4039973 A GB4039973 A GB 4039973A GB 4039973 A GB4039973 A GB 4039973A GB 1446352 A GB1446352 A GB 1446352A
Authority
GB
Grant status
Application
Patent type
Prior art keywords
cellulose
weight
pharmaceutical compositions
cholestyramine
parts
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB4039973A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Sharp & Dohme Corp
Original Assignee
Merck Sharp & Dohme Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0087Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/74Synthetic polymeric materials
    • A61K31/785Polymers containing nitrogen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38Cellulose; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals

Abstract

1446352 Pharmaceutical compositions MERCK & CO INC 28 Aug 1973 [1 Sept 1972] 40399/73 Heading A5B Oral palatable pharmaceutical compositions for the treatment of hypercholestermia and biliary cirrhosis comprise a coacervate of cholestyramine and a hydrophilic colloid of a cellulose derivative such as sodium carboxymethyl cellulose, methyl cellulose, ethyl cellulose, hydroxyethyl cellulose or hydroxy propyl cellulose. The composition may also contain a water-insoluble dispersing agent such as corn starch, potato starch or a carboxymethyl starch. A preferred composition comprises 8 to 10 parts by weight of cholestyramine, 0.8 to 1.3 parts by weight of dispersing agent and 1 part by weight of hydrophilic colloid. The compositions may be in the form of liquid preparations.
GB4039973A 1972-09-01 1973-08-28 Pharmaceutical compositions Expired GB1446352A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
US28571972 true 1972-09-01 1972-09-01

Publications (1)

Publication Number Publication Date
GB1446352A true true GB1446352A (en) 1976-08-18

Family

ID=23095432

Family Applications (1)

Application Number Title Priority Date Filing Date
GB4039973A Expired GB1446352A (en) 1972-09-01 1973-08-28 Pharmaceutical compositions

Country Status (5)

Country Link
CA (1) CA1014472A (en)
DE (1) DE2344090A1 (en)
FR (1) FR2197592B1 (en)
GB (1) GB1446352A (en)
NL (1) NL7311319A (en)

Cited By (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0190826A2 (en) * 1985-02-05 1986-08-13 Warner-Lambert Company Ingestible aggregate and delivery system incorporating the same
US4790991A (en) * 1985-02-05 1988-12-13 Warner-Lambert Company Ingestible aggregate and delivery system prepared therefrom
US4797288A (en) * 1984-10-05 1989-01-10 Warner-Lambert Company Novel drug delivery system
US4804548A (en) * 1984-10-05 1989-02-14 Warner-Lambert Company Novel sweetener delivery systems
US4818539A (en) * 1985-02-05 1989-04-04 Warner-Lambert Company Ingestible aggregate and delivery system prepared therefrom
US4828857A (en) * 1984-10-05 1989-05-09 Warner-Lambert Company Novel sweetener delivery systems
US4843098A (en) * 1985-02-05 1989-06-27 Warner-Lambert Company Ingestible aggregate and delivery system prepared therefrom
US4851392A (en) * 1985-02-05 1989-07-25 Warner-Lambert Company Ingestible aggregate and delivery system prepared therefrom
US4931280A (en) * 1988-06-13 1990-06-05 Basf K & F Corporation Edible, baked compositions containing cholestyramine
US5167965A (en) * 1987-02-09 1992-12-01 The Dow Chemical Company Palatable cholestyramine granules, tablets and methods for preparation thereof
US5500190A (en) * 1992-03-20 1996-03-19 The Procter & Gamble Company Anion exchange resin compositions containing almond paste for taste improvement
US5601837A (en) * 1990-12-20 1997-02-11 The Procter & Gamble Company Psyllium cholestyramine compositions with improved palatability

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4914084A (en) * 1984-05-09 1990-04-03 Synthetic Blood Corporation Composition and method for introducing heme, hemoproteins, and/or heme-hemoprotein complexes into the body
ES2044912T3 (en) * 1986-06-16 1994-01-16 Farkemo Srl pharmaceutical compositions endowed with sequestering activity for bile acid, cholestyramine containing as active ingredient, and method for its preparation.
GB8628359D0 (en) * 1986-11-27 1986-12-31 Zyma Sa Galenical formulation
CA1313135C (en) * 1987-02-09 1993-01-26 The Dow Chemical Company Cholestyramine composition and process for its preparation
EP0349103B1 (en) * 1988-05-04 1992-11-25 SMITH KLINE & FRENCH LABORATORIES LIMITED Chewable tablet
US5275823A (en) * 1989-04-27 1994-01-04 Smith Kline & French Laboratories Ltd. Pharmaceutical compositions
US5102664A (en) * 1989-07-19 1992-04-07 Day Charles E Good-tasting gritty drug formulations

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3499960A (en) * 1965-01-25 1970-03-10 Merck & Co Inc Palatable coated particles of an anion exchange resin

Cited By (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4797288A (en) * 1984-10-05 1989-01-10 Warner-Lambert Company Novel drug delivery system
US4828857A (en) * 1984-10-05 1989-05-09 Warner-Lambert Company Novel sweetener delivery systems
US4804548A (en) * 1984-10-05 1989-02-14 Warner-Lambert Company Novel sweetener delivery systems
EP0190826A2 (en) * 1985-02-05 1986-08-13 Warner-Lambert Company Ingestible aggregate and delivery system incorporating the same
US4790991A (en) * 1985-02-05 1988-12-13 Warner-Lambert Company Ingestible aggregate and delivery system prepared therefrom
US4747881A (en) * 1985-02-05 1988-05-31 Warner-Lambert Company Ingestible aggregate and delivery system prepared therefrom
US4818539A (en) * 1985-02-05 1989-04-04 Warner-Lambert Company Ingestible aggregate and delivery system prepared therefrom
EP0190826A3 (en) * 1985-02-05 1988-03-09 Warner-Lambert Company Ingestible aggregate and delivery system incorporating the same
US4843098A (en) * 1985-02-05 1989-06-27 Warner-Lambert Company Ingestible aggregate and delivery system prepared therefrom
US4851392A (en) * 1985-02-05 1989-07-25 Warner-Lambert Company Ingestible aggregate and delivery system prepared therefrom
US5167965A (en) * 1987-02-09 1992-12-01 The Dow Chemical Company Palatable cholestyramine granules, tablets and methods for preparation thereof
US4931280A (en) * 1988-06-13 1990-06-05 Basf K & F Corporation Edible, baked compositions containing cholestyramine
US5601837A (en) * 1990-12-20 1997-02-11 The Procter & Gamble Company Psyllium cholestyramine compositions with improved palatability
US5500190A (en) * 1992-03-20 1996-03-19 The Procter & Gamble Company Anion exchange resin compositions containing almond paste for taste improvement

Also Published As

Publication number Publication date Type
DE2344090A1 (en) 1974-03-21 application
FR2197592A1 (en) 1974-03-29 application
FR2197592B1 (en) 1976-08-13 grant
CA1014472A (en) 1977-07-26 grant
NL7311319A (en) 1974-03-05 application
CA1014472A1 (en) grant

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Legal Events

Date Code Title Description
PS Patent sealed
PCNP Patent ceased through non-payment of renewal fee