GB2000025A - Nitroimidazole formulations - Google Patents

Nitroimidazole formulations

Info

Publication number
GB2000025A
GB2000025A GB7827007A GB7827007A GB2000025A GB 2000025 A GB2000025 A GB 2000025A GB 7827007 A GB7827007 A GB 7827007A GB 7827007 A GB7827007 A GB 7827007A GB 2000025 A GB2000025 A GB 2000025A
Authority
GB
United Kingdom
Prior art keywords
nitroimidazole
formulations
mono
formulation
antimicrobial
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
GB7827007A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Ltd
Original Assignee
Pfizer Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Ltd filed Critical Pfizer Ltd
Priority to GB7827007A priority Critical patent/GB2000025A/en
Publication of GB2000025A publication Critical patent/GB2000025A/en
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Dermatology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

A nitroimidazole antimicrobial formulation having improved solubility characteristics comprises a nitroimidazole antimicrobial drug in admixture with a pharmaceutically acceptable salt of a mono or di-hydroxybenzoic acid or with a mono or di-hydroxybenzyl alcohol. The formulation is used to prepare an aqueous injectable solution for intravenous administration.
GB7827007A 1977-05-14 1978-06-15 Nitroimidazole formulations Withdrawn GB2000025A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
GB7827007A GB2000025A (en) 1977-05-14 1978-06-15 Nitroimidazole formulations

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB2037977 1977-05-14
GB7827007A GB2000025A (en) 1977-05-14 1978-06-15 Nitroimidazole formulations

Publications (1)

Publication Number Publication Date
GB2000025A true GB2000025A (en) 1979-01-04

Family

ID=26254630

Family Applications (1)

Application Number Title Priority Date Filing Date
GB7827007A Withdrawn GB2000025A (en) 1977-05-14 1978-06-15 Nitroimidazole formulations

Country Status (1)

Country Link
GB (1) GB2000025A (en)

Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0013625A2 (en) * 1979-01-10 1980-07-23 Israel Marcus Solubilized thymidine composition and method of producing same
EP0031561A2 (en) * 1979-12-20 1981-07-08 Merck & Co. Inc. A rectally administered suppository comprising a drug and an adjuvant
FR2560043A1 (en) * 1983-08-19 1985-08-30 May & Baker Ltd NEW INJECTABLE COMPOSITIONS BASED ON (2-HYDROXY ETHYL -) - 1 NITRO-5 IMIDAZOLE
AU738165B2 (en) * 1996-06-28 2001-09-13 Oxigene, Inc. Useful formulations of acid addition salt drugs
CN1321637C (en) * 2002-09-29 2007-06-20 中国药科大学 Chinese medicinal hypoglycemic agent and preparation thereof
EP1962600A2 (en) * 2005-12-08 2008-09-03 SSCI, Inc. Metronidazole cocrystals and imipramine cocrystals
US8258164B2 (en) * 2006-09-12 2012-09-04 Curatek Pharmaceuticals Holding, Inc. Nitroimidazole composition and method
CN102933213A (en) * 2010-04-14 2013-02-13 益友制药私人有限公司 Radiation sensitiser compositions
CN110538146A (en) * 2019-10-08 2019-12-06 四川太平洋药业有限责任公司 levoornidazole sodium chloride injection and preparation process thereof
CN110664739A (en) * 2019-10-08 2020-01-10 四川太平洋药业有限责任公司 Ornidazole sodium chloride injection and preparation process thereof

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
None *

Cited By (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0013625A2 (en) * 1979-01-10 1980-07-23 Israel Marcus Solubilized thymidine composition and method of producing same
EP0013625A3 (en) * 1979-01-10 1980-10-15 Israel Marcus Solubilized thymidine composition and method of producing same
EP0031561A2 (en) * 1979-12-20 1981-07-08 Merck & Co. Inc. A rectally administered suppository comprising a drug and an adjuvant
EP0031561A3 (en) * 1979-12-20 1982-08-11 Merck & Co. Inc. A rectally administered drug form comprising a drug and an adjuvant
DK156121B (en) * 1979-12-20 1989-06-26 Merck & Co Inc PROCEDURE FOR PREPARING A RECTAL ADMINISTRATIVE SUPPLY WITH A ADJUVANCE
FR2560043A1 (en) * 1983-08-19 1985-08-30 May & Baker Ltd NEW INJECTABLE COMPOSITIONS BASED ON (2-HYDROXY ETHYL -) - 1 NITRO-5 IMIDAZOLE
AU738165B2 (en) * 1996-06-28 2001-09-13 Oxigene, Inc. Useful formulations of acid addition salt drugs
CN1321637C (en) * 2002-09-29 2007-06-20 中国药科大学 Chinese medicinal hypoglycemic agent and preparation thereof
EP1962600A2 (en) * 2005-12-08 2008-09-03 SSCI, Inc. Metronidazole cocrystals and imipramine cocrystals
EP1962600A4 (en) * 2005-12-08 2010-09-22 Ssci Inc Metronidazole cocrystals and imipramine cocrystals
US8163790B2 (en) 2005-12-08 2012-04-24 New Form Pharmaceuticals, Inc. Metronidazole cocrystals and imipramine cocrystals
US8258164B2 (en) * 2006-09-12 2012-09-04 Curatek Pharmaceuticals Holding, Inc. Nitroimidazole composition and method
CN102933213A (en) * 2010-04-14 2013-02-13 益友制药私人有限公司 Radiation sensitiser compositions
EP2558090A1 (en) * 2010-04-14 2013-02-20 Eupharma Pty Ltd Radiation sensitiser compositions
EP2558090A4 (en) * 2010-04-14 2013-05-08 Eupharma Pty Ltd Radiation sensitiser compositions
CN110538146A (en) * 2019-10-08 2019-12-06 四川太平洋药业有限责任公司 levoornidazole sodium chloride injection and preparation process thereof
CN110664739A (en) * 2019-10-08 2020-01-10 四川太平洋药业有限责任公司 Ornidazole sodium chloride injection and preparation process thereof

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Legal Events

Date Code Title Description
WAP Application withdrawn, taken to be withdrawn or refused ** after publication under section 16(1)