KR890701109A - 스테로이드 로숀 - Google Patents
스테로이드 로숀Info
- Publication number
- KR890701109A KR890701109A KR1019890700100A KR890700100A KR890701109A KR 890701109 A KR890701109 A KR 890701109A KR 1019890700100 A KR1019890700100 A KR 1019890700100A KR 890700100 A KR890700100 A KR 890700100A KR 890701109 A KR890701109 A KR 890701109A
- Authority
- KR
- South Korea
- Prior art keywords
- lotion
- weight
- corticosteroid
- usp
- composition
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Dermatology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Steroid Compounds (AREA)
- Cosmetics (AREA)
- Medicines Containing Plant Substances (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
내용 없음
Description
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음
Claims (18)
15내지 50중량%의 프로필렌 글리콜 ; 20내지 40중량%의 이소프로필 알코올 ; 20 내지 60중량%의 물 ; 0.1내지 0.5중량%의 농후제, 및 조성물의 pH를 3.0내지 6.0의 범위로 유지시키기에 충분한 완충액을 함유하는 하이드로 - 알코올성 기제 중의 피부학적 허용되는 소염성 코르티코스테로이드의 염증 치료 유효량을 함유함을 특징으로 하는 염증 치료를 위한 국소형 로숀.
제 1 항에 있어서, 코르티코스테로이드가 조성물의 0.01 내지 1.0중량%를 구성함을 특징으로 하는 로숀.
제 2 항에 있어서, 코르티코스테로이드가 조성물의 0.02 내지 0.2중량%를 구성함을 특징으로 하는 로숀.
제 1 항에 있어서, 코르티코스테로이드가 베타메타숀 17, 21 - 디프로피오네이트인 로숀.
제 4 항에 있어서, 베타메타손 17, 21 - 디프로피오네이트가 0.064중량%의 양으로 존재하는 로숀.
제 5 항에 있어서, 하기 조성으로 이루어짐을 특징으로 하는 로숀.
농 도
성 분mg/gmg/g
베타메타손 디프로피오네이트, USP 0.64*
일염기성 인산나트륨 일수화물, R 2.00
인산, NF * *
수산화나트륨, R * *
프로필렌 글리콜, USP 300.00
이소프로필 알코올, USP 300,00
하이드록시프로필 셀룰로즈, NF 1.50
정제수, USP 적당량 1.00g
0.5mg베타메타손/g과 등량
pH 4.5 ±0.2까지로 조절하는 데 사용
제 1 항에 있어서, 코르티코스테로이드가 알클로메타손 디프로피오네이트인 로숀.
제 7 항에 있어서, 하기 조성으로 이루어짐을 특징으로 하는 로숀.
농 도
성 분mg/gmg/g
알클로메타손 디프로피오네이트 0.5
카보머 940 2.60
수산화나트륨, R 0.04
프로필렌 글리콜, USP 200.0
이소프로필 알코올, NF 300.0
염산 *
정제수, USP 적당량으로 1.0g까지
* pH 4.5까지 조절하는데 사용
제 1 항에 있어서, 코르티코스테로이드가 모메타손 푸로에이트인 로숀.
제 9 항에 있어서, 하기 조성으로 이루어짐을 특징으로 하는 로숀.
농 도
성 분mg/gmg/g
모메타손 푸로에이트 1.0
알코올 이소프로필, USP 400.0
프로필렌 글리콜, USP 300.0
하이드록시프로필 셀룰로즈(Klucel HF) 1.5
일염기성 인산나트륨 일수화물 R 2.0
인산, NF *
정제수, USP 적당량 1g
pH 4.5 ±0.1까지 조절하는데 사용
제 1 항에 있어서, 농후제가 아크릴산 중합체인 로숀.
제 1 항에 있어서, 농후제가 하이드록시프로필 셀룰로즈인 로숀.
15내지 50중량%의 프로필렌 글리콜 ; 20내지 40중량%의 이소프로필 알코올 ; 20내지 60중량%의 물 ; 0.1내지 0.5중량%의 농후제, 및 조성물의 pH를 3.0내지 6.0의 범위로 유지시키기에 충분한 완충액을 함유하는 하이드로 - 알코올성 기제 중의 피부학적으로 허용되는 소염성 코르티코스테로이드의 염증 치료 유효량을 함유함을 특징으로 하는 국소용 로숀 체형을 피부에 적응시킴을 특징으로 하는 염증 치료 방법.
제13항에 있어서, 코르티코스테로이드가 조성물의 0.01 내지 1.0중량%를 구성함을 특징으로 하는 방법.
제14항에 있어서, 코르티코스테로이드가 조성물의 0.02 내지 0.2중량%를 구성함을 특징으로 하는 방법.
제13항에 있어서, 코르티코스테로이드가 베타메타손 17, 21 - 디프로피오네이트인 방법.
제13항에 있어서, 코르티코스테로이드가 알클로메타손 디프로피오네이트인 방법.
제13항에 있어서, 코르티코스테로이드가 모메타숀 푸로에이트인 방법.
※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US07/053,172 US4775529A (en) | 1987-05-21 | 1987-05-21 | Steroid lotion |
US053172 | 1987-05-21 | ||
PCT/US1988/001606 WO1988009174A1 (en) | 1987-05-21 | 1988-05-20 | Steroid lotion |
Publications (1)
Publication Number | Publication Date |
---|---|
KR890701109A true KR890701109A (ko) | 1989-12-19 |
Family
ID=21982389
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
KR1019890700100A KR930010584B1 (ko) | 1987-05-21 | 1988-05-20 | 스테로이드 로숀 |
KR1019890700100A KR890701109A (ko) | 1987-05-21 | 1988-05-20 | 스테로이드 로숀 |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
KR1019890700100A KR930010584B1 (ko) | 1987-05-21 | 1988-05-20 | 스테로이드 로숀 |
Country Status (22)
Country | Link |
---|---|
US (1) | US4775529A (ko) |
EP (2) | EP0362270B2 (ko) |
JP (1) | JP2572124B2 (ko) |
KR (2) | KR930010584B1 (ko) |
AT (1) | ATE77745T1 (ko) |
AU (1) | AU616188B2 (ko) |
CA (1) | CA1307207C (ko) |
DE (1) | DE3872521T3 (ko) |
DK (1) | DK581989D0 (ko) |
ES (1) | ES2032898T5 (ko) |
FI (1) | FI95350C (ko) |
GR (2) | GR3005762T3 (ko) |
HK (1) | HK60595A (ko) |
IE (1) | IE60546B1 (ko) |
IL (1) | IL86440A (ko) |
MX (1) | MX9203285A (ko) |
MY (1) | MY103280A (ko) |
NO (1) | NO175762C (ko) |
NZ (1) | NZ224707A (ko) |
PH (1) | PH24528A (ko) |
WO (1) | WO1988009174A1 (ko) |
ZA (1) | ZA883566B (ko) |
Families Citing this family (26)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4942158A (en) * | 1988-10-13 | 1990-07-17 | Eastman Kodak | Transdermal steroid penetrant compositions and methods utilizing isopropanol and isobutanol |
US5241925A (en) * | 1988-12-27 | 1993-09-07 | Dermamed | Apparatus and techniques for administering veterinary medicaments |
US5332577A (en) * | 1988-12-27 | 1994-07-26 | Dermamed | Transdermal administration to humans and animals |
US4988500A (en) * | 1989-09-29 | 1991-01-29 | The Procter & Gamble Company | Oral compositions |
US5324521A (en) * | 1989-12-18 | 1994-06-28 | Dermamed | Systems for transdermal administration of medicaments |
US5087620A (en) * | 1990-05-17 | 1992-02-11 | Bristol-Myers Squibb Co. | Controlled dermal penetration enhancement using imidazoles |
IL99437A (en) | 1990-09-10 | 1995-05-29 | Schering Corp | Mumtazone Foroat Monohydrate, its preparation method and medicinal preparations |
US6127353A (en) * | 1991-09-06 | 2000-10-03 | Schering Corporation | Mometasone furoate monohydrate, process for making same and pharmaceutical compositions |
DE69433923T2 (de) * | 1993-12-21 | 2005-07-21 | Schering Corp. | Salbe enthaltend mometason-furoat und salicylsäure zur topischen behandlung von psoriasis |
DE4344697A1 (de) * | 1993-12-27 | 1995-06-29 | Beiersdorf Ag | Corticosteroide enthaltende W/O-Lotion |
US6623744B2 (en) | 1995-06-22 | 2003-09-23 | 3M Innovative Properties Company | Stable hydroalcoholic compositions |
US7566460B2 (en) * | 1995-06-22 | 2009-07-28 | 3M Innovative Properties Company | Stable hydroalcoholic compositions |
EP0833605A1 (en) * | 1995-06-22 | 1998-04-08 | Minnesota Mining And Manufacturing Company | Stable hydroalcoholic compositions |
US5696105A (en) * | 1996-03-14 | 1997-12-09 | Hackler; Walter A. | Antifungal nail composition |
US6582711B1 (en) * | 1997-01-09 | 2003-06-24 | 3M Innovative Properties Company | Hydroalcoholic compositions thickened using polymers |
CA2282682C (en) * | 1997-02-20 | 2008-08-19 | Allergan Sales, Inc. | Tazarotene and corticosteroid treatment for psoriasis |
US5879711A (en) * | 1997-11-07 | 1999-03-09 | Sequeira; Joel A. | Stable antiandrogenic gel composition |
FI974610A0 (fi) * | 1997-12-23 | 1997-12-23 | Leiras Oy | Farmaceutiskt preparat i gelform |
US8329758B2 (en) * | 2002-02-05 | 2012-12-11 | Gojo Industries, Inc. | Skin sanitizing antimicrobial alcoholic compositions |
KR20040034795A (ko) * | 2002-10-17 | 2004-04-29 | 박래옥 | 스테로이드 제제 및 태반 추출물을 함유한 염증성 피부병치료용 경피제 |
WO2004105686A2 (en) | 2003-05-23 | 2004-12-09 | Taro Pharmaceuticals U.S.A., Inc. | Novel topical steroid cream formulations |
WO2006130510A2 (en) * | 2005-05-27 | 2006-12-07 | Taro Pharmaceuticals U.S.A., Inc. | Stable liquid desoximethasone compositions with reduced oxidized impurity |
US20070099883A1 (en) * | 2005-10-07 | 2007-05-03 | Cheryl Lynn Calis | Anhydrous mometasone furoate formulation |
MX2008007439A (es) * | 2005-12-09 | 2009-01-22 | Nycomed Inc | Formulaciones glucocorticosteroides topicas. |
US20090082318A1 (en) * | 2007-09-26 | 2009-03-26 | Protia, Llc | Deuterium-enriched mometasone |
EP2394653A1 (en) | 2010-05-26 | 2011-12-14 | Almirall, S.A. | Topical pharmaceutical compositions comprising mometasone furoate |
Family Cites Families (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2890152A (en) * | 1956-11-29 | 1959-06-09 | Schering Corp | Topical anti-inflammatory compositions |
US3352752A (en) * | 1963-07-25 | 1967-11-14 | Tintex Corp | Intestinal adsorbent compositions |
US3592930A (en) * | 1968-07-19 | 1971-07-13 | Syntex Corp | Moisture-deterioratable topical medicaments,particularly anti-inflammatory steroids,in a substantially non-aqueous fatty alcohol-propylene glycol vehicle |
US3711606A (en) * | 1970-09-02 | 1973-01-16 | Crown Zellerbach Corp | Enhancing tissue penetration of physiologically active steroidal agents with dmso |
DK135267A (ko) * | 1971-02-25 | |||
US3758686A (en) * | 1971-12-07 | 1973-09-11 | American Cyanamid Co | Method of using steroid acetonides |
GB1382614A (en) * | 1972-01-10 | 1975-02-05 | Squibb & Sons Inc | Steroid compositions |
US3892857A (en) * | 1972-11-24 | 1975-07-01 | Squibb & Sons Inc | Steroid formulation |
US4013792A (en) * | 1974-04-11 | 1977-03-22 | Warner-Lambert Company | Process for the production of base for topical steroids |
US4185100A (en) * | 1976-05-13 | 1980-01-22 | Johnson & Johnson | Topical anti-inflammatory drug therapy |
US4070462A (en) * | 1976-10-26 | 1978-01-24 | Schering Corporation | Steroid ointment |
CA1163561A (en) * | 1979-11-06 | 1984-03-13 | Cyril Boroda | Preparation containing nitroglycerine and optionally other medicaments and preparation thereof |
ATE8790T1 (de) * | 1981-02-02 | 1984-08-15 | Schering Corporation | Aromatische heterocyclische steroidester, verfahren zu ihrer herstellung und pharmazeutische zusammensetzungen, die sie enthalten. |
US4489070A (en) * | 1983-05-13 | 1984-12-18 | Schering Corporation | Betamethasone dipropionate cream |
US4557934A (en) * | 1983-06-21 | 1985-12-10 | The Procter & Gamble Company | Penetrating topical pharmaceutical compositions containing 1-dodecyl-azacycloheptan-2-one |
JPS6013711A (ja) * | 1983-06-21 | 1985-01-24 | ザ、プロクタ−、エンド、ギヤンブル、カンパニ− | コルチコステロイドを含有する浸透局所製薬組成物 |
US4552872A (en) * | 1983-06-21 | 1985-11-12 | The Procter & Gamble Company | Penetrating topical pharmaceutical compositions containing corticosteroids |
US4489071A (en) * | 1983-12-09 | 1984-12-18 | Schering Corporation | Betamethasone dipropionate cream |
-
1987
- 1987-05-21 US US07/053,172 patent/US4775529A/en not_active Expired - Lifetime
-
1988
- 1988-05-18 PH PH36943A patent/PH24528A/en unknown
- 1988-05-19 IE IE151788A patent/IE60546B1/en not_active IP Right Cessation
- 1988-05-19 MY MYPI88000528A patent/MY103280A/en unknown
- 1988-05-19 NZ NZ224707A patent/NZ224707A/xx unknown
- 1988-05-19 ZA ZA883566A patent/ZA883566B/xx unknown
- 1988-05-19 IL IL86440A patent/IL86440A/xx not_active IP Right Cessation
- 1988-05-19 CA CA000567221A patent/CA1307207C/en not_active Expired - Lifetime
- 1988-05-20 WO PCT/US1988/001606 patent/WO1988009174A1/en active IP Right Grant
- 1988-05-20 AU AU19417/88A patent/AU616188B2/en not_active Ceased
- 1988-05-20 EP EP88905097A patent/EP0362270B2/en not_active Expired - Lifetime
- 1988-05-20 KR KR1019890700100A patent/KR930010584B1/ko active
- 1988-05-20 ES ES88108141T patent/ES2032898T5/es not_active Expired - Lifetime
- 1988-05-20 EP EP88108141A patent/EP0292893B2/en not_active Expired - Lifetime
- 1988-05-20 KR KR1019890700100A patent/KR890701109A/ko not_active IP Right Cessation
- 1988-05-20 DE DE3872521T patent/DE3872521T3/de not_active Expired - Lifetime
- 1988-05-20 JP JP63504797A patent/JP2572124B2/ja not_active Expired - Lifetime
- 1988-05-20 AT AT88905097T patent/ATE77745T1/de not_active IP Right Cessation
-
1989
- 1989-01-20 NO NO890271A patent/NO175762C/no not_active IP Right Cessation
- 1989-11-17 FI FI895482A patent/FI95350C/fi not_active IP Right Cessation
- 1989-11-20 DK DK581989A patent/DK581989D0/da not_active Application Discontinuation
-
1992
- 1992-06-24 MX MX9203285A patent/MX9203285A/es unknown
- 1992-09-23 GR GR920402093T patent/GR3005762T3/el unknown
-
1995
- 1995-04-20 HK HK60595A patent/HK60595A/xx not_active IP Right Cessation
-
1996
- 1996-01-30 GR GR960400206T patent/GR3018818T3/el unknown
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