IE37718L - Pharmaceutical compositions - Google Patents

Pharmaceutical compositions

Info

Publication number
IE37718L
IE37718L IE730858A IE85873A IE37718L IE 37718 L IE37718 L IE 37718L IE 730858 A IE730858 A IE 730858A IE 85873 A IE85873 A IE 85873A IE 37718 L IE37718 L IE 37718L
Authority
IE
Ireland
Prior art keywords
june
pharmaceutical compositions
edetate
gb1397893a
carboxypoylmethylene
Prior art date
Application number
IE730858A
Other versions
IE37718B1 (en
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of IE37718L publication Critical patent/IE37718L/en
Publication of IE37718B1 publication Critical patent/IE37718B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/76—Nitrogen atoms to which a second hetero atom is attached
    • C07D213/77—Hydrazine radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Dermatology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

1397893 Pharmaceutical compositions MERCK & CO INC 4 June 1973 [9 June 1972 30 June 1972] 26492/73 Heading A5B Anti-inflammatory compositions for topical administration comprise 2'-(4-pyridyl)-6, 16α- dimethyl-11#-17α, 21-trihydroxypregna-4, 6-diene [3, 2-c] pyrazol-20-one or a pharmaceutically acceptable salt thereof and a clear waterwhite gel including water, at least one organic solvent such as ethyl alcohol, isopropyl alcohol, propylene glycol, glycerine, 2-octyl dodecanol and methyl pyrrolidine, and at least one thickening agent such as hydroxyethyl cellulose, hydroxypropyl cellulose and a carboxypoylmethylene having a molecular weight of 940. The composition may also contain a stabilizing agent such as disodium edetate, sodium citrate, dipotassium edetate and citric acid. [GB1397893A]
IE858/73A 1972-06-09 1973-05-29 Pharmaceutical compositions IE37718B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US26118672A 1972-06-09 1972-06-09
US26774372A 1972-06-30 1972-06-30

Publications (2)

Publication Number Publication Date
IE37718L true IE37718L (en) 1973-12-09
IE37718B1 IE37718B1 (en) 1977-09-28

Family

ID=26948452

Family Applications (1)

Application Number Title Priority Date Filing Date
IE858/73A IE37718B1 (en) 1972-06-09 1973-05-29 Pharmaceutical compositions

Country Status (8)

Country Link
CA (1) CA1014856A (en)
DE (1) DE2329130A1 (en)
FR (1) FR2187340B1 (en)
GB (1) GB1397893A (en)
IE (1) IE37718B1 (en)
IL (1) IL42365A (en)
NL (1) NL7307072A (en)
PH (1) PH10968A (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0112852B1 (en) * 1982-06-24 1988-06-08 SMITH, Robert Alan Pharmaceutical gel composition
WO1990014833A1 (en) * 1989-06-07 1990-12-13 Bazzano Gail S Slow release vehicles for minimizing skin irritancy of topical compositions

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK135267A (en) * 1971-02-25
BE786884A (en) * 1971-07-30 1973-01-29 Merck & Co Inc STERANIC PYRAZOLE AND PROCESS

Also Published As

Publication number Publication date
IL42365A0 (en) 1973-07-30
IE37718B1 (en) 1977-09-28
DE2329130A1 (en) 1973-12-20
GB1397893A (en) 1975-06-18
IL42365A (en) 1977-04-29
CA1014856A (en) 1977-08-02
AU5625573A (en) 1974-12-05
PH10968A (en) 1977-10-18
FR2187340A1 (en) 1974-01-18
NL7307072A (en) 1973-12-11
FR2187340B1 (en) 1976-10-22

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