GB1362444A - 2-nitro-imidazole derivatives and methods for their preparation - Google Patents

2-nitro-imidazole derivatives and methods for their preparation

Info

Publication number
GB1362444A
GB1362444A GB3288672A GB3288672A GB1362444A GB 1362444 A GB1362444 A GB 1362444A GB 3288672 A GB3288672 A GB 3288672A GB 3288672 A GB3288672 A GB 3288672A GB 1362444 A GB1362444 A GB 1362444A
Authority
GB
United Kingdom
Prior art keywords
nitro
alkyl
imidazolaldehyde
reacting
aldehyde
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB3288672A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Gruppo Lepetit SpA
Original Assignee
Gruppo Lepetit SpA
Lepetit SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gruppo Lepetit SpA, Lepetit SpA filed Critical Gruppo Lepetit SpA
Publication of GB1362444A publication Critical patent/GB1362444A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/91—Nitro radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
GB3288672A 1971-07-30 1972-07-13 2-nitro-imidazole derivatives and methods for their preparation Expired GB1362444A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT4297871 1971-07-30

Publications (1)

Publication Number Publication Date
GB1362444A true GB1362444A (en) 1974-08-07

Family

ID=11254772

Family Applications (1)

Application Number Title Priority Date Filing Date
GB3288672A Expired GB1362444A (en) 1971-07-30 1972-07-13 2-nitro-imidazole derivatives and methods for their preparation

Country Status (27)

Country Link
US (1) US3954789A (enExample)
JP (2) JPS5038111B1 (enExample)
AR (4) AR193885A1 (enExample)
AT (3) AT315164B (enExample)
AU (1) AU462723B2 (enExample)
BE (1) BE785024A (enExample)
CA (1) CA997340A (enExample)
CH (4) CH574933A5 (enExample)
CS (1) CS180585B2 (enExample)
DD (2) DD99995A5 (enExample)
DE (2) DE2229248C3 (enExample)
DK (1) DK154295C (enExample)
ES (3) ES405341A1 (enExample)
FI (1) FI57255C (enExample)
FR (1) FR2148073B1 (enExample)
GB (1) GB1362444A (enExample)
HU (2) HU167622B (enExample)
IE (1) IE36530B1 (enExample)
IL (1) IL39880A (enExample)
LU (1) LU65816A1 (enExample)
NL (2) NL148602B (enExample)
NO (2) NO135592C (enExample)
PL (4) PL84350B1 (enExample)
RO (6) RO63047A (enExample)
SE (3) SE417711B (enExample)
SU (4) SU466684A3 (enExample)
ZA (1) ZA724723B (enExample)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1480192A (en) * 1975-01-15 1977-07-20 Lepetit Spa 1-methyl-2-nitro-imidazole-5-methanol derivatives
GB1526451A (en) * 1976-01-27 1978-09-27 Lepetit Spa Alpha,alpha,1-trimethyl-2-nitroimidazole-5-methanol derivatives
US4218460A (en) * 1976-09-29 1980-08-19 Basf Aktiengesellschaft Nitroimidazoles
US4199592A (en) * 1978-08-29 1980-04-22 E. I. Du Pont De Nemours And Company Antiinflammatory 4,5-diaryl-2-nitroimidazoles
ZW24982A1 (en) * 1981-11-30 1983-06-15 Hoffmann La Roche 2-nitroimidazoles
JPH10338673A (ja) * 1997-06-04 1998-12-22 Nippon Bayeragrochem Kk イソニコチン酸ヒドラジド誘導体および有害生物防除剤
ZA200507752B (en) 2003-03-28 2007-01-31 Threshold Pharmaceuticals Inc Compositions and methods for treating cancer
CN102746336B (zh) 2005-06-29 2015-08-19 施瑞修德制药公司 氨基磷酸酯烷化剂前体药物
EP2114157B1 (en) 2006-12-26 2021-05-26 ImmunoGenesis, Inc. Phosphoramidate alkylator prodrug for the treatment of cancer

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL124627C (enExample) * 1964-08-12
NL143227B (nl) * 1968-11-15 1974-09-16 Lepetit Spa Werkwijze ter bereiding van imidazoolderivaten met bactericide werking.
US3583985A (en) * 1969-04-09 1971-06-08 Richardson Merrell Inc Nitroimidazolyl nitrones
US3711495A (en) * 1970-01-07 1973-01-16 Merck & Co Inc Isoxazalin-3-yl-substituted-5-nitroimidazoles

Also Published As

Publication number Publication date
DE2229248A1 (de) 1973-02-15
RO63453A (fr) 1978-06-15
US3954789A (en) 1976-05-04
HU167622B (enExample) 1975-11-28
DE2229248C3 (de) 1980-03-27
HU164926B (enExample) 1974-05-28
RO62787A (enExample) 1977-08-15
PL87673B1 (enExample) 1976-07-31
CH574933A5 (enExample) 1976-04-30
FI57255C (fi) 1980-07-10
FI57255B (fi) 1980-03-31
DE2229248B2 (de) 1979-07-26
NO135591B (enExample) 1977-01-17
DD99996A5 (enExample) 1973-09-05
SU567404A3 (ru) 1977-07-30
NL149491B (nl) 1976-05-17
IE36530L (en) 1973-01-30
ZA724723B (en) 1973-04-25
LU65816A1 (enExample) 1972-11-29
DE2229223B2 (de) 1975-05-07
AR199680A1 (es) 1974-09-23
DE2229223A1 (de) 1973-02-15
CH572040A5 (enExample) 1976-01-30
AT316545B (de) 1974-07-10
IL39880A (en) 1976-04-30
FR2148073B1 (enExample) 1975-11-28
AT323736B (de) 1975-07-25
SE417711B (sv) 1981-04-06
JPS528832B1 (enExample) 1977-03-11
FR2148073A1 (enExample) 1973-03-11
NL148602B (nl) 1976-02-16
SE392615B (sv) 1977-04-04
SU581863A3 (ru) 1977-11-25
BE785024A (fr) 1972-10-16
AR193885A1 (es) 1973-05-31
NL7210339A (enExample) 1973-02-01
AU462723B2 (en) 1975-07-03
DK154295C (da) 1989-03-28
CS180585B2 (en) 1978-01-31
PL82980B1 (enExample) 1975-12-31
DE2229223C3 (de) 1975-12-18
NO135592C (enExample) 1977-04-27
NL7210340A (enExample) 1973-02-01
NO135591C (enExample) 1977-04-27
PL85190B1 (enExample) 1976-04-30
DK154295B (da) 1988-10-31
IL39880A0 (en) 1972-09-28
AR193999A1 (es) 1973-06-12
PL84350B1 (enExample) 1976-03-31
RO63047A (fr) 1978-05-15
RO63048A (fr) 1978-05-15
ES418921A1 (es) 1976-10-16
CA997340A (en) 1976-09-21
SE417200B (sv) 1981-03-02
RO61517A (enExample) 1976-12-15
CH580596A5 (enExample) 1976-10-15
SE7503080L (enExample) 1975-03-18
NO135592B (enExample) 1977-01-17
AT315164B (de) 1974-05-10
CH574934A5 (enExample) 1976-04-30
ES405341A1 (es) 1975-07-01
DD99995A5 (enExample) 1973-09-05
AU4422872A (en) 1974-01-10
ES405343A1 (es) 1975-07-16
AR199084A1 (es) 1974-08-08
RO63049A (fr) 1978-07-15
SU463263A3 (ru) 1975-03-05
SU466684A3 (ru) 1975-04-05
JPS5038111B1 (enExample) 1975-12-06
IE36530B1 (en) 1976-11-24

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Legal Events

Date Code Title Description
PS Patent sealed [section 19, patents act 1949]
PCNP Patent ceased through non-payment of renewal fee