GB1335261A - Isoquinoline derivatives - Google Patents

Isoquinoline derivatives

Info

Publication number
GB1335261A
GB1335261A GB45471A GB45471A GB1335261A GB 1335261 A GB1335261 A GB 1335261A GB 45471 A GB45471 A GB 45471A GB 45471 A GB45471 A GB 45471A GB 1335261 A GB1335261 A GB 1335261A
Authority
GB
United Kingdom
Prior art keywords
compound
formula
alkoxy
alkyl
reducing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB45471A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of GB1335261A publication Critical patent/GB1335261A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C07D217/18—Aralkyl radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C07D217/14—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
GB45471A 1970-01-06 1971-01-05 Isoquinoline derivatives Expired GB1335261A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH10370A CH527194A (de) 1970-01-06 1970-01-06 Verfahren zur Herstellung von Isochinolin-Derivaten

Publications (1)

Publication Number Publication Date
GB1335261A true GB1335261A (en) 1973-10-24

Family

ID=4179328

Family Applications (1)

Application Number Title Priority Date Filing Date
GB45471A Expired GB1335261A (en) 1970-01-06 1971-01-05 Isoquinoline derivatives

Country Status (19)

Country Link
JP (1) JPS5515476B1 (https=)
AT (1) AT303041B (https=)
BE (1) BE761219A (https=)
CA (1) CA999866A (https=)
CH (2) CH538477A (https=)
DE (1) DE2062001C2 (https=)
DK (1) DK125021B (https=)
ES (1) ES387016A1 (https=)
FI (1) FI49503C (https=)
FR (1) FR2081412B1 (https=)
GB (1) GB1335261A (https=)
IE (1) IE34859B1 (https=)
IL (1) IL35916A (https=)
NL (1) NL171444C (https=)
NO (1) NO135315C (https=)
PH (1) PH9682A (https=)
SE (3) SE386672B (https=)
YU (1) YU33660B (https=)
ZA (1) ZA708590B (https=)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2271566A (en) * 1992-10-14 1994-04-20 Merck & Co Inc HIV integrase inhibitors
WO2006138714A3 (en) * 2005-06-17 2007-03-15 Janssen Pharmaceutica Nv Naphthyridine compounds

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA844402B (en) * 1983-06-23 1986-01-29 Mcneil Pharmaceutical Hexahydropyrrolo(2,1-a)isoquinoline derivatives
US4719216A (en) * 1983-06-23 1988-01-12 Mcneilab, Inc. Hexahydropyrrolo(2,1-A)isoquinoline derivatives as antidepressants
US4595688A (en) * 1983-06-23 1986-06-17 Mcneilab, Inc. Hexahydropyrrolo[2,1-a]isoquinoline derivatives and antidepressant use thereof
US7163949B1 (en) * 1999-11-03 2007-01-16 Amr Technology, Inc. 4-phenyl substituted tetrahydroisoquinolines and use thereof
MXPA02004330A (es) 1999-11-03 2004-07-30 Albany Molecular Res Inc Tetrahidroisoquinolinas aril-y heteroaril-sustituidas y uso de las mismas para bloquear la recaptacion de norepinefrina, dopamina y serotonina..
JP4907817B2 (ja) * 1999-11-03 2012-04-04 エーエムアール テクノロジー インコーポレイテッド ノルエピネフリン、ドーパミンおよびセロトニンの再取り込みを遮断するための、４−フェニル置換テトラヒドロイソキノリン類およびその利用
EP1113007A1 (en) * 1999-12-24 2001-07-04 Pfizer Inc. Tetrahydroisoquinoline compounds as estrogen agonists/antagonists
KR100821410B1 (ko) 2000-07-11 2008-04-10 에이엠알 테크놀로지, 인크. 4-페닐 치환된 테트라하이드로이소퀴놀린 및 이의치료학적 용도
UA91341C2 (ru) 2004-07-15 2010-07-26 Амр Текнолоджи, Інк. Арил- и гетероарилзамещенные тетрагидроизохинолины и их применение для блокирования обратного захвата норэпинефрина, допамина и серотонина
UA95454C2 (uk) 2005-07-15 2011-08-10 Амр Текнолоджи, Інк. Арил- і гетероарилзаміщені тетрагідробензазепіни і їх застосування для блокування зворотного захоплення норепінефрину, допаміну і серотоніну
US9156812B2 (en) 2008-06-04 2015-10-13 Bristol-Myers Squibb Company Crystalline form of 6-[(4S)-2-methyl-4-(2-naphthyl)-1,2,3,4-tetrahydroisoquinolin-7-yl]pyridazin-3-amine
AR071997A1 (es) 2008-06-04 2010-07-28 Bristol Myers Squibb Co Forma cristalina de 6-((4s)-2-metil-4-(2-naftil)-1,2,3,4-tetrahidroisoquinolin-7-il)piridazin-3-amina
EP2429295B1 (en) 2009-05-12 2013-12-25 Albany Molecular Research, Inc. Aryl, heteroaryl, and heterocycle substituted tetrahydroisoquinolines and use thereof
AU2010247763B2 (en) 2009-05-12 2015-12-24 Albany Molecular Research, Inc. 7-([1,2,4,]triazolo[1,5,-a]pyridin-6-yl)-4-(3,4-dichlorophenyl)-1,2,3,4- tetrahydroisoquinoline and use thereof
US8815894B2 (en) 2009-05-12 2014-08-26 Bristol-Myers Squibb Company Crystalline forms of (S)-7-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydroisoquinoline and use thereof

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1670694B2 (de) * 1966-05-05 1976-07-22 Hoechst Ag, 6000 Frankfurt Verfahren zur herstellung von tetrahydroisochinolinen

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2271566A (en) * 1992-10-14 1994-04-20 Merck & Co Inc HIV integrase inhibitors
WO2006138714A3 (en) * 2005-06-17 2007-03-15 Janssen Pharmaceutica Nv Naphthyridine compounds
US7417054B2 (en) 2005-06-17 2008-08-26 Janssen Pharmaceutica N.V. Naphthyridine compounds

Also Published As

Publication number Publication date
FI49503B (https=) 1975-04-01
FR2081412A1 (https=) 1971-12-03
NL171444B (nl) 1982-11-01
SE399879B (sv) 1978-03-06
JPS5515476B1 (https=) 1980-04-23
AT303041B (de) 1972-11-10
DK125021B (da) 1972-12-18
IE34859L (en) 1971-07-06
CA999866A (en) 1976-11-16
CH527194A (de) 1972-08-31
YU1971A (en) 1977-06-30
PH9682A (en) 1976-02-10
ES387016A1 (es) 1976-05-01
CH538477A (de) 1973-06-30
NL171444C (nl) 1983-04-05
BE761219A (fr) 1971-07-05
NO135315C (https=) 1977-03-23
NO135315B (https=) 1976-12-13
IL35916A0 (en) 1971-02-25
SE386672B (sv) 1976-08-16
SE368401B (https=) 1974-07-01
FR2081412B1 (https=) 1974-04-12
NL7018956A (https=) 1971-07-08
DE2062001A1 (de) 1971-07-15
IE34859B1 (en) 1975-09-03
IL35916A (en) 1973-11-28
DE2062001C2 (de) 1986-10-16
FI49503C (fi) 1975-07-10
YU33660B (en) 1977-12-31
ZA708590B (en) 1971-09-29

Similar Documents

Publication Publication Date Title
GB1335261A (en) Isoquinoline derivatives
GB1409693A (en) Triazolobenzodiazepines
GB1474882A (en) Alpha-aminomethyl-5-hydroxy-2-pyridinemethanols
GB1493998A (en) Propanolamine derivatives
GB1111451A (en) Improvements in or relating to pharmacologically-active secondary amine compounds
GB1456627A (en) Pyridobenzodiazepinones
GB1443692A (en) 1,2-diphenylethanolamine derivatives and their salts and the preparation thereof
GB1394568A (en) Diazepine derivatives and process for the production thereof
GB1462095A (en) Substituted triazolo-1,5-benzodiazepines
GB1238777A (https=)
GB1434580A (en) Disubstituted piperazines
GB1206088A (en) New pyrazolodiazepinone compounds and methods for their production
GB1208231A (en) beta-PHENETHYLAMINE DERIVATIVES AND A PROCESS FOR THE MANUFACTURE THEREOF
GB1433078A (en) Substituted phenethylamines
GB1345214A (en) Isoxazoles
GB1283632A (en) Phenylethanolamine derivatives
SE7415496L (https=)
GB1468079A (en) Ethanolamine derivatives
GB1451389A (en) Indolobenzazepines
GB1211459A (en) Hydroxy amines
GB1408984A (en) Beta-adrenergic blocking aminopropanols
GB1340407A (en) Phenylethanolamine derivatives
SE333735B (https=)
GB1234967A (en) Alkanolamine derivatives
GB1446164A (en) Basic enol ethers their salts processes for their preparation and pharmaceutical preparations containing the same

Legal Events

Date Code Title Description
PS Patent sealed [section 19, patents act 1949]
PCNP Patent ceased through non-payment of renewal fee