GB0716292D0 - Imidazopyrazine compounds - Google Patents

Imidazopyrazine compounds

Info

Publication number
GB0716292D0
GB0716292D0 GBGB0716292.8A GB0716292A GB0716292D0 GB 0716292 D0 GB0716292 D0 GB 0716292D0 GB 0716292 A GB0716292 A GB 0716292A GB 0716292 D0 GB0716292 D0 GB 0716292D0
Authority
GB
United Kingdom
Prior art keywords
imidazopyrazine compounds
imidazopyrazine
compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
GBGB0716292.8A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Biofocus DPI Ltd
Original Assignee
Biofocus DPI Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biofocus DPI Ltd filed Critical Biofocus DPI Ltd
Priority to GBGB0716292.8A priority Critical patent/GB0716292D0/en
Publication of GB0716292D0 publication Critical patent/GB0716292D0/en
Priority to US12/674,525 priority patent/US8362018B2/en
Priority to AU2008290531A priority patent/AU2008290531A1/en
Priority to DK08787346.9T priority patent/DK2193131T3/da
Priority to PL08787346T priority patent/PL2193131T3/pl
Priority to ES08787346T priority patent/ES2404415T3/es
Priority to JP2010521417A priority patent/JP2010536825A/ja
Priority to BRPI0815717-0A2A priority patent/BRPI0815717A2/pt
Priority to SI200830948T priority patent/SI2193131T1/sl
Priority to EP08787346A priority patent/EP2193131B1/en
Priority to CN2008801108961A priority patent/CN101835780B/zh
Priority to NZ584108A priority patent/NZ584108A/en
Priority to PT87873469T priority patent/PT2193131E/pt
Priority to HK10110351.0A priority patent/HK1143810B/en
Priority to HRP20130202AT priority patent/HRP20130202T1/hr
Priority to PCT/EP2008/060896 priority patent/WO2009024585A2/en
Priority to MX2010001733A priority patent/MX2010001733A/es
Priority to KR1020107005549A priority patent/KR20100081294A/ko
Priority to EP12188861.4A priority patent/EP2567960A3/en
Priority to CA2707521A priority patent/CA2707521A1/en
Priority to ZA2010/02009A priority patent/ZA201002009B/en
Priority to CY20131100277T priority patent/CY1113872T1/el
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
GBGB0716292.8A 2007-08-21 2007-08-21 Imidazopyrazine compounds Ceased GB0716292D0 (en)

Priority Applications (22)

Application Number Priority Date Filing Date Title
GBGB0716292.8A GB0716292D0 (en) 2007-08-21 2007-08-21 Imidazopyrazine compounds
CA2707521A CA2707521A1 (en) 2007-08-21 2008-08-20 Imidazopyrazine compounds
CN2008801108961A CN101835780B (zh) 2007-08-21 2008-08-20 用于治疗病毒感染诸如肝炎的咪唑并[1,2-a]吡嗪化合物
PT87873469T PT2193131E (pt) 2007-08-21 2008-08-20 Compostos de imidazol[1,2-a]pirazina para o tratamento de infecções virais tais como a hepatite
DK08787346.9T DK2193131T3 (da) 2007-08-21 2008-08-20 Imidazo[1,2-a]pyrazinforbindelser til behandling af virusinfektioner såsom hepatitis
PL08787346T PL2193131T3 (pl) 2007-08-21 2008-08-20 Związki imidazo[1,2-a]pirazyny w leczeniu infekcji wirusowych takich jak zapalenia wątroby
ES08787346T ES2404415T3 (es) 2007-08-21 2008-08-20 Compuestos de imidazo[1,2-a]pirazina para el tratamiento de infecciones virales tales como la hepatitis
JP2010521417A JP2010536825A (ja) 2007-08-21 2008-08-20 肝炎などのウイルス感染の治療用イミダゾ[1,2−a]ピラジン化合物
BRPI0815717-0A2A BRPI0815717A2 (pt) 2007-08-21 2008-08-20 Compostos de imidazopirazina.
SI200830948T SI2193131T1 (sl) 2007-08-21 2008-08-20 Imidazo(1,2-A)pirazin spojine za zdravljenje virusnih okuĹľb kot je hepatitis
EP08787346A EP2193131B1 (en) 2007-08-21 2008-08-20 Imidazo[1,2-a]pyrazine compounds for treatment of viral infections such as hepatitis
US12/674,525 US8362018B2 (en) 2007-08-21 2008-08-20 Substituted imidazo[1,2-a]pyrazine compounds useful for the treatment of viral infections
NZ584108A NZ584108A (en) 2007-08-21 2008-08-20 Imidazo [1,2-a] pyrazine compounds for treatment of viral infections such as hepatitis
AU2008290531A AU2008290531A1 (en) 2007-08-21 2008-08-20 Imidazo [1,2-a] pyrazine compounds for treatment of viral infections such as hepatitis
HK10110351.0A HK1143810B (en) 2007-08-21 2008-08-20 Imidazo [1,2-a] pyrazine compounds for treatment of viral infections such as hepatitis
HRP20130202AT HRP20130202T1 (hr) 2007-08-21 2008-08-20 Spojevi imidazo[1,2-a] pirazina za lijeäśenje virusnih infekcija kao što je hepatitis
PCT/EP2008/060896 WO2009024585A2 (en) 2007-08-21 2008-08-20 Imidazo [1,2-a] pyrazine compounds for treatment of viral infections such as hepatitis
MX2010001733A MX2010001733A (es) 2007-08-21 2008-08-20 Compustos de imidazo[1,2-a]pirazina para tratamiento de infecciones virales tales como hepatitis.
KR1020107005549A KR20100081294A (ko) 2007-08-21 2008-08-20 간염과 같은 바이러스성 감염 치료용 이미다조[1,2-a] 피라진 화합물
EP12188861.4A EP2567960A3 (en) 2007-08-21 2008-08-20 Imidazo[1,2-a]pyrazine compounds for treatment of viral infections such as hepatitis
ZA2010/02009A ZA201002009B (en) 2007-08-21 2010-03-19 Imidazo[1,2-a] pyrazine compounds for treatment of viral infections such as hepatitis
CY20131100277T CY1113872T1 (el) 2007-08-21 2013-04-03 Ενωσεις imidazo[1,2-a]pyrazine για την θεραπεια μολυνσεων απο ιους οπως ηπατιτιδα

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0716292.8A GB0716292D0 (en) 2007-08-21 2007-08-21 Imidazopyrazine compounds

Publications (1)

Publication Number Publication Date
GB0716292D0 true GB0716292D0 (en) 2007-09-26

Family

ID=38566736

Family Applications (1)

Application Number Title Priority Date Filing Date
GBGB0716292.8A Ceased GB0716292D0 (en) 2007-08-21 2007-08-21 Imidazopyrazine compounds

Country Status (20)

Country Link
US (1) US8362018B2 (cg-RX-API-DMAC7.html)
EP (2) EP2567960A3 (cg-RX-API-DMAC7.html)
JP (1) JP2010536825A (cg-RX-API-DMAC7.html)
KR (1) KR20100081294A (cg-RX-API-DMAC7.html)
CN (1) CN101835780B (cg-RX-API-DMAC7.html)
AU (1) AU2008290531A1 (cg-RX-API-DMAC7.html)
BR (1) BRPI0815717A2 (cg-RX-API-DMAC7.html)
CA (1) CA2707521A1 (cg-RX-API-DMAC7.html)
CY (1) CY1113872T1 (cg-RX-API-DMAC7.html)
DK (1) DK2193131T3 (cg-RX-API-DMAC7.html)
ES (1) ES2404415T3 (cg-RX-API-DMAC7.html)
GB (1) GB0716292D0 (cg-RX-API-DMAC7.html)
HR (1) HRP20130202T1 (cg-RX-API-DMAC7.html)
MX (1) MX2010001733A (cg-RX-API-DMAC7.html)
NZ (1) NZ584108A (cg-RX-API-DMAC7.html)
PL (1) PL2193131T3 (cg-RX-API-DMAC7.html)
PT (1) PT2193131E (cg-RX-API-DMAC7.html)
SI (1) SI2193131T1 (cg-RX-API-DMAC7.html)
WO (1) WO2009024585A2 (cg-RX-API-DMAC7.html)
ZA (1) ZA201002009B (cg-RX-API-DMAC7.html)

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GB0716292D0 (en) * 2007-08-21 2007-09-26 Biofocus Dpi Ltd Imidazopyrazine compounds
JP5216912B2 (ja) 2008-04-29 2013-06-19 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング Ccr1受容体拮抗薬としてのインダゾール化合物
JP5411927B2 (ja) 2008-05-06 2014-02-12 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング Ccr1アンタゴニストとしてのピラゾール化合物
PE20110854A1 (es) 2008-09-26 2011-12-23 Boehringer Ingelheim Int DERIVADOS DE 1-FENIL-1H-PIRAZOLO[3,4-c]PIRIDINA-4-CARBONILAMINA COMO ANTAGONISTAS DE LOS RECEPTORES CCR1
TW201107329A (en) 2009-07-30 2011-03-01 Oncotherapy Science Inc Fused imidazole derivative having ttk inhibitory action
AP2012006204A0 (en) 2009-10-21 2012-04-30 Boehringer Ingelheim Int Indazole and pyrazolopyridine compounds as CCR1 receptor antagonists.
JP5542214B2 (ja) 2009-10-27 2014-07-09 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング Ccr1受容体アンタゴニストとしての複素環化合物
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WO2012080228A1 (en) 2010-12-17 2012-06-21 Bayer Pharma Aktiengesellschaft 6-thio-substituted imidazopyrazines for use as mps-1 and tkk inhibitors in the treatment of hyperproliferative disorders
WO2012080232A1 (en) * 2010-12-17 2012-06-21 Bayer Pharma Aktiengesellschaft 2-substituted imidazopyrazines for use as mps-1 and tkk inhibitors in the treatment of hyperproliferative disorders
US9284317B2 (en) * 2010-12-17 2016-03-15 Bayer Intellectual Property Gmbh Substituted imidazo[1,2-a]pyrazines as MPS-1 inhibitors
US20140187548A1 (en) 2010-12-17 2014-07-03 Bayer Intellectual Property Gmbh 6 substituted imidazopyrazines for use as mps-1 and tkk inhibitors in the treatment of hyperproliferative disorders
US8546442B2 (en) 2010-12-23 2013-10-01 Boehringer Ingelheim International Gmbh Pyrazolopiperidine compounds as CCR1 receptor antagonists
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JPWO2013061962A1 (ja) * 2011-10-24 2015-04-02 武田薬品工業株式会社 二環性化合物
WO2014001314A1 (en) 2012-06-26 2014-01-03 Janssen Pharmaceutica Nv Combinations comprising pde 2 inhibitors such as 1-aryl-4-methyl- [1,2,4] triazolo [4,3-a] quinoxaline compounds and pde 10 inhibitors for use in the treatment of neurological or metabolic disorders
AU2013289284B2 (en) 2012-07-09 2017-03-30 Janssen Pharmaceutica Nv Inhibitors of phosphodiesterase 10 enzyme
WO2016130501A1 (en) 2015-02-09 2016-08-18 Incyte Corporation Aza-heteroaryl compounds as pi3k-gamma inhibitors
BR112017023038A2 (pt) * 2015-04-29 2018-07-03 Janssen Pharmaceutica Nv imidazopirazinas e pirazolopirimidinas e seu uso como moduladores do receptor ampa
BR122023023802A2 (pt) 2015-04-29 2023-12-26 Janssen Pharmaceutica Nv Compostos azabenzimidazóis, seu uso como moduladores do receptor de ampa e composições farmacêuticas que os compreendem
CN107949563B (zh) * 2015-06-24 2020-06-05 库洛维公司 治疗中有用的吡唑并[1,5-a]三嗪-4-胺衍生物
JP6507976B2 (ja) * 2015-09-30 2019-05-08 東レ株式会社 イミダゾール−2−カルボン酸エステル誘導体又はその塩の製造方法
RS63359B1 (sr) 2015-11-06 2022-07-29 Incyte Corp Heterociklična jedinjenja kao inhibitori pi3k-gama
ES2995198T3 (en) 2016-01-05 2025-02-07 Incyte Corp Pyridine compounds as pi3k-gamma inhibitors
HK1250945A1 (zh) * 2016-03-31 2019-01-18 罗马克实验室有限公司 用於治疗病毒性感染的噻唑化物化合物
TW201803871A (zh) 2016-06-24 2018-02-01 英塞特公司 作為PI3K-γ抑制劑之雜環化合物
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KR102717072B1 (ko) 2017-10-18 2024-10-15 인사이트 코포레이션 Pi3k-감마 저해제로서의 3차 하이드록시기로 치환된 축합된 이미다졸 유도체
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TWI811428B (zh) 2018-08-21 2023-08-11 日商杏林製藥股份有限公司 雙環雜芳香環衍生物
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CN109369545B (zh) * 2018-12-14 2020-04-10 东营曜康医药科技有限公司 2-甲基-5-甲酸吡嗪的合成工艺
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WO2021061803A1 (en) 2019-09-23 2021-04-01 Nanjing Zhengxiang Pharmaceuticals Co., Ltd. Phosphodiesterase inhibitors and use
CN115667266A (zh) 2020-06-01 2023-01-31 豪夫迈·罗氏有限公司 新型咪唑并吡嗪衍生物
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CN113929633A (zh) * 2021-10-27 2022-01-14 山东大学 一种法匹拉韦的合成方法及其应用
CN113831255B (zh) * 2021-11-25 2022-03-11 山东诚创蓝海医药科技有限公司 一种2-氨基丙二酰胺的制备方法
CN115489188B (zh) * 2022-10-09 2023-08-29 安徽国风新材料股份有限公司 一种家居保护用聚酯薄膜及其制备方法
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Also Published As

Publication number Publication date
DK2193131T3 (da) 2013-04-22
WO2009024585A2 (en) 2009-02-26
NZ584108A (en) 2012-06-29
EP2193131B1 (en) 2013-01-30
BRPI0815717A2 (pt) 2015-02-10
MX2010001733A (es) 2010-07-06
ES2404415T3 (es) 2013-05-27
EP2567960A3 (en) 2013-06-05
ZA201002009B (en) 2010-12-29
US8362018B2 (en) 2013-01-29
HRP20130202T1 (hr) 2013-04-30
EP2193131A2 (en) 2010-06-09
HK1143810A1 (en) 2011-01-14
WO2009024585A3 (en) 2009-08-06
KR20100081294A (ko) 2010-07-14
PT2193131E (pt) 2013-04-04
US20110166147A1 (en) 2011-07-07
PL2193131T3 (pl) 2013-07-31
AU2008290531A1 (en) 2009-02-26
CN101835780A (zh) 2010-09-15
CA2707521A1 (en) 2009-02-26
SI2193131T1 (sl) 2013-06-28
EP2567960A2 (en) 2013-03-13
JP2010536825A (ja) 2010-12-02
CY1113872T1 (el) 2016-07-27
CN101835780B (zh) 2013-09-18

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