FR2515182B1 - Nouveaux produits derives de l'acide 3-amino 2-oxo azetidine 1-sulfamique, leur procede de preparation, leur application comme medicaments et les produits intermediaires necessaires a leur preparation - Google Patents

Nouveaux produits derives de l'acide 3-amino 2-oxo azetidine 1-sulfamique, leur procede de preparation, leur application comme medicaments et les produits intermediaires necessaires a leur preparation

Info

Publication number
FR2515182B1
FR2515182B1 FR8119946A FR8119946A FR2515182B1 FR 2515182 B1 FR2515182 B1 FR 2515182B1 FR 8119946 A FR8119946 A FR 8119946A FR 8119946 A FR8119946 A FR 8119946A FR 2515182 B1 FR2515182 B1 FR 2515182B1
Authority
FR
France
Prior art keywords
preparation
medicaments
amino
application
sulfamic acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR8119946A
Other languages
English (en)
Other versions
FR2515182A1 (fr
Inventor
Rene Heymes
Alain Bonnet
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis France
Original Assignee
Roussel Uclaf SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf SA filed Critical Roussel Uclaf SA
Priority to FR8119946A priority Critical patent/FR2515182B1/fr
Priority to SE8205870A priority patent/SE461655B/sv
Priority to LU84434A priority patent/LU84434A1/fr
Priority to NL8204089A priority patent/NL8204089A/nl
Priority to DE3239157A priority patent/DE3239157C2/de
Priority to CH6166/82A priority patent/CH655317A5/fr
Priority to CH326385A priority patent/CH661504A5/fr
Priority to BE0/209311A priority patent/BE894785A/fr
Priority to IT49341/82A priority patent/IT1157233B/it
Priority to CA000413983A priority patent/CA1201439A/fr
Priority to JP57184814A priority patent/JPS58135883A/ja
Priority to GB08230366A priority patent/GB2111482B/en
Priority to AT0391182A priority patent/AT382150B/de
Priority to FR8221648A priority patent/FR2538389B2/fr
Publication of FR2515182A1 publication Critical patent/FR2515182A1/fr
Priority to FR8400799A priority patent/FR2558467B2/fr
Priority to GB08500023A priority patent/GB2151628B/en
Priority to AT216985A priority patent/AT389695B/de
Application granted granted Critical
Publication of FR2515182B1 publication Critical patent/FR2515182B1/fr
Priority to SE8702330A priority patent/SE500849C2/sv
Priority to US07/068,141 priority patent/US4900728A/en
Priority to JP3122828A priority patent/JPH0730018B2/ja
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • C07D205/085—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a nitrogen atom directly attached in position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
FR8119946A 1981-10-23 1981-10-23 Nouveaux produits derives de l'acide 3-amino 2-oxo azetidine 1-sulfamique, leur procede de preparation, leur application comme medicaments et les produits intermediaires necessaires a leur preparation Expired FR2515182B1 (fr)

Priority Applications (20)

Application Number Priority Date Filing Date Title
FR8119946A FR2515182B1 (fr) 1981-10-23 1981-10-23 Nouveaux produits derives de l'acide 3-amino 2-oxo azetidine 1-sulfamique, leur procede de preparation, leur application comme medicaments et les produits intermediaires necessaires a leur preparation
SE8205870A SE461655B (sv) 1981-10-23 1982-10-15 3-amino-2-oxo-azetidin-1-sulfonsyraderivat, saett foer framstaellning daerav samt naemnda derivat till anvaendning som laekemedel
NL8204089A NL8204089A (nl) 1981-10-23 1982-10-22 Nieuwe van 3-amino 2-oxo-azetidine 1-sulfonzuur afgeleide verbindingen, hun bereiding, hun toepassing als geneesmiddelen, de samenstellingen die ze bevatten en de verkregen nieuwe tussenprodukten.
DE3239157A DE3239157C2 (de) 1981-10-23 1982-10-22 3-Oximinoacylamino-4-fluormethyl-1-sulfoazetidinone, ihre Herstellung, Zwischenprodukte und pharmazeutische Zusammensetzungen
CH6166/82A CH655317A5 (fr) 1981-10-23 1982-10-22 Derives de l'acide 3-amino 2-oxo azetidine 1-sulfonique, leur preparation, medicaments et compositions les renfermant.
CH326385A CH661504A5 (fr) 1981-10-23 1982-10-22 Derives de la 3-amino 2-oxo azetidine et leur preparation.
BE0/209311A BE894785A (fr) 1981-10-23 1982-10-22 Nouveaux produits derives de l'acide 3-amino 2-oxo azetidine 1-sulfonique, leur preparation, leur application comme medicaments, les compositions les renfermant et les produits intermediaires nouveaux obtenus
IT49341/82A IT1157233B (it) 1981-10-23 1982-10-22 Prodotti originali derivati dall'acido 3-ammino 2-osso azetidin 1-solfonico, procedimento per la loro preparazione, loro applicazione come medicamenti, composizioni che li contengono e prodotti intermedi originali ottenuti
CA000413983A CA1201439A (fr) 1981-10-23 1982-10-22 Procede de preparation de nouveaux derives de l'acide 3-amino 2-oxo azetidine 1-sulfamique
JP57184814A JPS58135883A (ja) 1981-10-23 1982-10-22 新規化合物の３―アミノ―２―オキソアゼチジン―１―スルホン酸の誘導体及びそれらの製造法
LU84434A LU84434A1 (fr) 1981-10-23 1982-10-22 Nouveaux produits derives de l'acide 3-amino 2-oxo azetidine 1-sulfamide,leur preparation,leur application comme medicaments,les compositions les renfermant et les produits intermediaires nouveaux obtenus
AT0391182A AT382150B (de) 1981-10-23 1982-10-25 Verfahren zur herstellung von neuen 3-amino-2-oxo-azetidin-1-sulfonsaeurederivaten
GB08230366A GB2111482B (en) 1981-10-23 1982-10-25 Azetidine medicaments
FR8221648A FR2538389B2 (fr) 1981-10-23 1982-12-23 Nouveaux produits derives de l'acide 3-amino 2-oxo azetidine-1-sulfamique, nouveau procede de preparation de produits optiquement actifs, application des nouveaux produits comme medicaments et produits necessaires a leur preparation
FR8400799A FR2558467B2 (fr) 1981-10-23 1984-01-19 Nouveau produit derive de l'acide 3-amino 2-oxo azetidine 1-sulfamique, son procede de preparation, son application comme medicament et un produit intermediaire necessaire a sa preparation
GB08500023A GB2151628B (en) 1981-10-23 1985-01-02 Azetidine intermediates
AT216985A AT389695B (de) 1981-10-23 1985-07-22 Verfahren zur herstellung von neuen 3-amino-2-oxo-azetidin-1-sulfonderivaten
SE8702330A SE500849C2 (sv) 1981-10-23 1987-06-04 Nya 3-amino-2-oxo-azetidin-1-sulfonsyror, mellanprodukter till motsvarande 3-aminosubstituerade-2-oxo-azetidin-1-sulfonsyror
US07/068,141 US4900728A (en) 1981-10-23 1987-06-29 Novel 3-amino-2-oxo-azetidine-1-sulfonic acids
JP3122828A JPH0730018B2 (ja) 1981-10-23 1991-04-26 新規化合物の３−アミノ−２−オキソアゼチジン誘導体及びそれらの製造法

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8119946A FR2515182B1 (fr) 1981-10-23 1981-10-23 Nouveaux produits derives de l'acide 3-amino 2-oxo azetidine 1-sulfamique, leur procede de preparation, leur application comme medicaments et les produits intermediaires necessaires a leur preparation

Publications (2)

Publication Number Publication Date
FR2515182A1 FR2515182A1 (fr) 1983-04-29
FR2515182B1 true FR2515182B1 (fr) 1986-05-09

Family

ID=9263337

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8119946A Expired FR2515182B1 (fr) 1981-10-23 1981-10-23 Nouveaux produits derives de l'acide 3-amino 2-oxo azetidine 1-sulfamique, leur procede de preparation, leur application comme medicaments et les produits intermediaires necessaires a leur preparation

Country Status (12)

Country Link
JP (2) JPS58135883A (fr)
AT (1) AT382150B (fr)
BE (1) BE894785A (fr)
CA (1) CA1201439A (fr)
CH (1) CH655317A5 (fr)
DE (1) DE3239157C2 (fr)
FR (1) FR2515182B1 (fr)
GB (1) GB2111482B (fr)
IT (1) IT1157233B (fr)
LU (1) LU84434A1 (fr)
NL (1) NL8204089A (fr)
SE (2) SE461655B (fr)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1982001873A1 (fr) * 1980-12-05 1982-06-10 Takeda Chemical Industries Ltd Derives 1-sulfo-2-oxoazetidine et leur procede de preparation
MX7096E (es) * 1980-12-05 1987-06-19 Takeda Chemical Industries Ltd Metodo para preparacion de derivados de 2-oxoazetidina
US4675397A (en) * 1980-12-05 1987-06-23 Takeda Chemical Industries, Ltd. 1-sulfo-2-oxoazetidine derivatives and their production
US4673739A (en) * 1980-12-05 1987-06-16 Takeda Chemical Industries, Ltd. 4-carbamoyloxymethyl-1-sulfo-2-oxoazetidine derivatives and their production
US4572801A (en) * 1981-04-30 1986-02-25 Takeda Chemical Industries, Ltd. 4-Carbamoyloxymethyl-1-sulfo-2-oxoazetidine derivatives and their production
FR2558467B2 (fr) * 1981-10-23 1987-03-20 Roussel Uclaf Nouveau produit derive de l'acide 3-amino 2-oxo azetidine 1-sulfamique, son procede de preparation, son application comme medicament et un produit intermediaire necessaire a sa preparation
US4443374A (en) * 1982-02-01 1984-04-17 E. R. Squibb & Sons, Inc. Process for preparing (3S)-3-[[(2-amino-4-thiazolyl)[(1-carboxy-1-methylethoxy)imino]-acetyl]amino]-2-oxo-1-azetidinesulfonic acid, and 4-substituted derivatives
JPS58208288A (ja) * 1982-05-31 1983-12-03 Banyu Pharmaceut Co Ltd ２−オキソ−１−アゼチジンスルホン酸誘導体
JPS59175490A (ja) * 1983-03-24 1984-10-04 Banyu Pharmaceut Co Ltd ２−オキソ−１−アゼチジンスルホン酸誘導体
EP0096296B1 (fr) * 1982-06-03 1987-07-29 F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft Dérivés de 1-sulfo-2-oxoazétidine
DE3377061D1 (en) * 1982-06-03 1988-07-21 Hoffmann La Roche Process for the preparation of 1-sulfo-2-oxoazetidine derivatives
JPS5982359A (ja) * 1982-11-02 1984-05-12 Kanegafuchi Chem Ind Co Ltd ４（Ｒ）配位光学活性β−ラクタム化合物の製法
EP0117053A1 (fr) * 1983-02-10 1984-08-29 Ajinomoto Co., Inc. Dérivés de l'azétidinone
JPS59231086A (ja) * 1983-06-15 1984-12-25 Teikoku Hormone Mfg Co Ltd ４−メトキシエチル−２−アゼチジノン−１−スルホン酸誘導体
US4501697A (en) * 1983-06-17 1985-02-26 E. R. Squibb & Sons, Inc. 4-[[(Amidomethyl)oxy]methyl]-2-oxo-1-azetidinesulfonic acid salts
JPS6097978A (ja) * 1983-10-31 1985-05-31 Otsuka Chem Co Ltd ３−アシルアミノ−４−メチル−２−アゼチジノン−１−スルホン酸誘導体，その製造方法および該誘導体を含有する薬剤
JPS60202882A (ja) * 1984-03-27 1985-10-14 Teikoku Hormone Mfg Co Ltd 新規な２−アゼチジノン−１−スルホン酸誘導体
WO1986006722A1 (fr) * 1985-05-09 1986-11-20 The Upjohn Company Monobactames substitues par du carbonate servant d'antibiotiques
US4837318A (en) * 1985-05-09 1989-06-06 The Upjohn Company Carbonate substituted monobactams as antibiotics
DE19642530A1 (de) * 1996-10-15 1998-04-16 Bayer Ag Halogenalkoximinoessigsäureamide
US6677028B1 (en) 1999-09-10 2004-01-13 3M Innovative Properties Company Retroreflective articles having multilayer films and methods of manufacturing same

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4166816A (en) * 1975-05-05 1979-09-04 Smithkline Corporation Methods and intermediates for preparing cis-4-oxoazetidine intermediates
DK194776A (da) * 1975-05-05 1976-11-06 Smithkline Corp Antibakterielle midler og mellemprodukter dertil
FR2361885A1 (fr) * 1975-09-03 1978-03-17 Smithkline Corp Analogues de la penicilline, leurs intermediaires et procedes pour leur obtention
US4085100A (en) * 1976-11-01 1978-04-18 Smithkline Corporation Intermediate for dephthaloylation of azetidinone compounds
US4144333A (en) * 1976-11-15 1979-03-13 Smithkline Corporation Monocyclic beta-lactams with antibacterial activity
EP0005507A1 (fr) * 1978-05-18 1979-11-28 Ciba-Geigy Ag Procédé pour la scission de dérivés de 3-(2-hydroxyimino-acétylamino)-2-oxo-azétidine et les composés obtenus
EP0021678B1 (fr) * 1979-06-08 1984-11-07 Takeda Chemical Industries, Ltd. Dérivés de 1-sulfo-2-azétidinone, leur préparation et leurs compositions pharmaceutiques
NZ196202A (en) * 1980-02-07 1984-07-31 Squibb & Sons Inc Beta-lactam antibiotics (of azetidine-sulphonic acid type)
WO1982001873A1 (fr) * 1980-12-05 1982-06-10 Takeda Chemical Industries Ltd Derives 1-sulfo-2-oxoazetidine et leur procede de preparation
JPS57131758A (en) * 1980-12-05 1982-08-14 Takeda Chem Ind Ltd 1-sulfo-2-oxoazetidine derivative, its preparation and use
JPS58189176A (ja) 1982-04-30 1983-11-04 Takeda Chem Ind Ltd １−スルホ−２−アゼチジノン誘導体およびその製造法
JPS58210061A (ja) 1982-05-31 1983-12-07 Takeda Chem Ind Ltd １−スルホ−２−オキソアゼチジン誘導体、その製造法および用途
ATE24726T1 (de) * 1981-10-05 1987-01-15 Squibb & Sons Inc 4-aether-derivate von 2-azetidinon-1-sulfonsaeuren.
AU564150B2 (en) * 1982-04-30 1987-08-06 Takeda Chemical Industries Ltd. 1-sulfo-2-azetidinone derivatives
JPS59175490A (ja) * 1983-03-24 1984-10-04 Banyu Pharmaceut Co Ltd ２−オキソ−１−アゼチジンスルホン酸誘導体
HU189290B (en) * 1982-05-31 1986-06-30 Banyu Pharmaceutical Co Ltd,Jp Process for preparing new 2-oxo-1-azetidine-sulphonic acid derivatives and pharmaceutically acceptable salts thereof, further pharmaceutical compositions containing such derivatives as active substances
JPS58208288A (ja) * 1982-05-31 1983-12-03 Banyu Pharmaceut Co Ltd ２−オキソ−１−アゼチジンスルホン酸誘導体

Also Published As

Publication number Publication date
JPH04234844A (ja) 1992-08-24
IT1157233B (it) 1987-02-11
GB2111482B (en) 1985-11-06
AT382150B (de) 1987-01-12
SE8205870L (sv) 1983-04-24
GB2111482A (en) 1983-07-06
SE8702330L (sv) 1987-06-04
SE8702330D0 (sv) 1987-06-04
SE500849C2 (sv) 1994-09-19
BE894785A (fr) 1983-04-22
DE3239157C2 (de) 1994-04-28
CH655317A5 (fr) 1986-04-15
DE3239157A1 (de) 1983-05-05
JPS58135883A (ja) 1983-08-12
CA1201439A (fr) 1986-03-04
NL8204089A (nl) 1983-05-16
FR2515182A1 (fr) 1983-04-29
SE8205870D0 (sv) 1982-10-15
IT8249341A0 (it) 1982-10-22
JPH0730018B2 (ja) 1995-04-05
SE461655B (sv) 1990-03-12
LU84434A1 (fr) 1983-06-13
JPH0471073B2 (fr) 1992-11-12
ATA391182A (de) 1986-06-15

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