GB2111482B - Azetidine medicaments - Google Patents

Azetidine medicaments

Info

Publication number
GB2111482B
GB2111482B GB08230366A GB8230366A GB2111482B GB 2111482 B GB2111482 B GB 2111482B GB 08230366 A GB08230366 A GB 08230366A GB 8230366 A GB8230366 A GB 8230366A GB 2111482 B GB2111482 B GB 2111482B
Authority
GB
United Kingdom
Prior art keywords
azetidine
medicaments
azetidine medicaments
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB08230366A
Other versions
GB2111482A (en
Inventor
Rene Heymes
Alain Bonnet
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis France
Original Assignee
Roussel Uclaf SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf SA filed Critical Roussel Uclaf SA
Publication of GB2111482A publication Critical patent/GB2111482A/en
Priority to GB08500023A priority Critical patent/GB2151628B/en
Application granted granted Critical
Publication of GB2111482B publication Critical patent/GB2111482B/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • C07D205/085—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a nitrogen atom directly attached in position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
GB08230366A 1981-10-23 1982-10-25 Azetidine medicaments Expired GB2111482B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
GB08500023A GB2151628B (en) 1981-10-23 1985-01-02 Azetidine intermediates

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8119946A FR2515182B1 (en) 1981-10-23 1981-10-23 NOVEL PRODUCTS DERIVED FROM 3-AMINO 2-OXO AZETIDINE 1-SULFAMIC ACID, THEIR PREPARATION PROCESS, THEIR APPLICATION AS MEDICAMENTS AND THE INTERMEDIATE PRODUCTS NECESSARY FOR THEIR PREPARATION

Publications (2)

Publication Number Publication Date
GB2111482A GB2111482A (en) 1983-07-06
GB2111482B true GB2111482B (en) 1985-11-06

Family

ID=9263337

Family Applications (1)

Application Number Title Priority Date Filing Date
GB08230366A Expired GB2111482B (en) 1981-10-23 1982-10-25 Azetidine medicaments

Country Status (12)

Country Link
JP (2) JPS58135883A (en)
AT (1) AT382150B (en)
BE (1) BE894785A (en)
CA (1) CA1201439A (en)
CH (1) CH655317A5 (en)
DE (1) DE3239157C2 (en)
FR (1) FR2515182B1 (en)
GB (1) GB2111482B (en)
IT (1) IT1157233B (en)
LU (1) LU84434A1 (en)
NL (1) NL8204089A (en)
SE (2) SE461655B (en)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1982001873A1 (en) * 1980-12-05 1982-06-10 Takeda Chemical Industries Ltd 1-sulfo-2-oxoazetidine derivatives and process for their preparation
US4673739A (en) * 1980-12-05 1987-06-16 Takeda Chemical Industries, Ltd. 4-carbamoyloxymethyl-1-sulfo-2-oxoazetidine derivatives and their production
US4675397A (en) * 1980-12-05 1987-06-23 Takeda Chemical Industries, Ltd. 1-sulfo-2-oxoazetidine derivatives and their production
MX7096E (en) * 1980-12-05 1987-06-19 Takeda Chemical Industries Ltd METHOD FOR PREPARATION OF 2-OXOAZETIDINE DERIVATIVES
US4572801A (en) * 1981-04-30 1986-02-25 Takeda Chemical Industries, Ltd. 4-Carbamoyloxymethyl-1-sulfo-2-oxoazetidine derivatives and their production
FR2558467B2 (en) * 1981-10-23 1987-03-20 Roussel Uclaf NEW PRODUCT DERIVED FROM 3-AMINO 2-OXO AZETIDINE 1-SULPHAMIC ACID, ITS PREPARATION PROCESS, ITS USE AS A MEDICAMENT AND AN INTERMEDIATE PRODUCT NECESSARY FOR ITS PREPARATION
US4443374A (en) * 1982-02-01 1984-04-17 E. R. Squibb & Sons, Inc. Process for preparing (3S)-3-[[(2-amino-4-thiazolyl)[(1-carboxy-1-methylethoxy)imino]-acetyl]amino]-2-oxo-1-azetidinesulfonic acid, and 4-substituted derivatives
JPS58208288A (en) * 1982-05-31 1983-12-03 Banyu Pharmaceut Co Ltd 2-oxo-1-azetidinesulfonic acid derivative
JPS59175490A (en) * 1983-03-24 1984-10-04 Banyu Pharmaceut Co Ltd 2-oxo-1-azetidinesulfonic acid derivative
DE3377061D1 (en) * 1982-06-03 1988-07-21 Hoffmann La Roche Process for the preparation of 1-sulfo-2-oxoazetidine derivatives
DE3372768D1 (en) * 1982-06-03 1987-09-03 Hoffmann La Roche 1-SULFO-2-OXOAZETIDINE DERIVATIVES
JPS5982359A (en) * 1982-11-02 1984-05-12 Kanegafuchi Chem Ind Co Ltd Preparation of 4(r) coordinated optically active beta-lactam compound
EP0117053A1 (en) * 1983-02-10 1984-08-29 Ajinomoto Co., Inc. Azetidinone derivatives
JPS59231086A (en) * 1983-06-15 1984-12-25 Teikoku Hormone Mfg Co Ltd 4-methoxyethyl-2-azetidinone-1-sulfonic acid derivative
US4501697A (en) * 1983-06-17 1985-02-26 E. R. Squibb & Sons, Inc. 4-[[(Amidomethyl)oxy]methyl]-2-oxo-1-azetidinesulfonic acid salts
JPS6097978A (en) * 1983-10-31 1985-05-31 Otsuka Chem Co Ltd 3-acylamino-4-methyl-2-azetidinone-1-sulfonic acid derivative, its production and drug containing said derivative
JPS60202882A (en) * 1984-03-27 1985-10-14 Teikoku Hormone Mfg Co Ltd Novel 2-azetidinone-1-sulfonic acid derivative
WO1986006722A1 (en) * 1985-05-09 1986-11-20 The Upjohn Company Carbonate substituted monobactams as antibiotics
US4837318A (en) * 1985-05-09 1989-06-06 The Upjohn Company Carbonate substituted monobactams as antibiotics
DE19642530A1 (en) * 1996-10-15 1998-04-16 Bayer Ag Haloalkoximinoacetic acid amides
US6677028B1 (en) 1999-09-10 2004-01-13 3M Innovative Properties Company Retroreflective articles having multilayer films and methods of manufacturing same

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK194776A (en) * 1975-05-05 1976-11-06 Smithkline Corp ANTIBACTERIAL MEDICINES AND INTERMEDIATE PRODUCTS THEREOF
US4166816A (en) * 1975-05-05 1979-09-04 Smithkline Corporation Methods and intermediates for preparing cis-4-oxoazetidine intermediates
FR2361885A1 (en) * 1975-09-03 1978-03-17 Smithkline Corp ANALOGUES OF PENICILLIN, THEIR INTERMEDIARIES AND METHODS FOR OBTAINING THEM
US4085100A (en) * 1976-11-01 1978-04-18 Smithkline Corporation Intermediate for dephthaloylation of azetidinone compounds
US4144333A (en) * 1976-11-15 1979-03-13 Smithkline Corporation Monocyclic beta-lactams with antibacterial activity
EP0005507A1 (en) * 1978-05-18 1979-11-28 Ciba-Geigy Ag Process for the fragmentation of 3-(2-hydroxyimino-acetylamino)-2-oxo azetidin compounds and compounds obtained thereby
EP0021678B1 (en) * 1979-06-08 1984-11-07 Takeda Chemical Industries, Ltd. 1-sulpho-2-oxoazetidine derivatives, their production and pharmaceutical compositions thereof
NZ205240A (en) * 1980-02-07 1984-07-31 Squibb & Sons Inc Sulphonamide derivatives,being starting materials for producing beta-lactams
WO1982001873A1 (en) * 1980-12-05 1982-06-10 Takeda Chemical Industries Ltd 1-sulfo-2-oxoazetidine derivatives and process for their preparation
JPS58189176A (en) 1982-04-30 1983-11-04 Takeda Chem Ind Ltd 1-sulfo-2-azetidinone derivative and its preparation
JPS58210061A (en) 1982-05-31 1983-12-07 Takeda Chem Ind Ltd 1-sulfo-2-oxoazetidine derivative, its preparation and use
JPS57131758A (en) * 1980-12-05 1982-08-14 Takeda Chem Ind Ltd 1-sulfo-2-oxoazetidine derivative, its preparation and use
EP0076758B1 (en) * 1981-10-05 1987-01-07 E.R. Squibb & Sons, Inc. 4-ether derivatives of 2-azetidinone-1-sulfonic acids
AU564150B2 (en) * 1982-04-30 1987-08-06 Takeda Chemical Industries Ltd. 1-sulfo-2-azetidinone derivatives
HU189290B (en) * 1982-05-31 1986-06-30 Banyu Pharmaceutical Co Ltd,Jp Process for preparing new 2-oxo-1-azetidine-sulphonic acid derivatives and pharmaceutically acceptable salts thereof, further pharmaceutical compositions containing such derivatives as active substances
JPS59175490A (en) * 1983-03-24 1984-10-04 Banyu Pharmaceut Co Ltd 2-oxo-1-azetidinesulfonic acid derivative
JPS58208288A (en) * 1982-05-31 1983-12-03 Banyu Pharmaceut Co Ltd 2-oxo-1-azetidinesulfonic acid derivative

Also Published As

Publication number Publication date
FR2515182B1 (en) 1986-05-09
IT8249341A0 (en) 1982-10-22
SE8205870D0 (en) 1982-10-15
DE3239157C2 (en) 1994-04-28
JPS58135883A (en) 1983-08-12
SE8205870L (en) 1983-04-24
IT1157233B (en) 1987-02-11
LU84434A1 (en) 1983-06-13
SE8702330D0 (en) 1987-06-04
NL8204089A (en) 1983-05-16
JPH0471073B2 (en) 1992-11-12
GB2111482A (en) 1983-07-06
SE461655B (en) 1990-03-12
CH655317A5 (en) 1986-04-15
AT382150B (en) 1987-01-12
FR2515182A1 (en) 1983-04-29
SE500849C2 (en) 1994-09-19
JPH04234844A (en) 1992-08-24
BE894785A (en) 1983-04-22
CA1201439A (en) 1986-03-04
ATA391182A (en) 1986-06-15
DE3239157A1 (en) 1983-05-05
JPH0730018B2 (en) 1995-04-05
SE8702330L (en) 1987-06-04

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Legal Events

Date Code Title Description
PCNP Patent ceased through non-payment of renewal fee

Effective date: 19961025