FR2468576B1 - - Google Patents
Info
- Publication number
- FR2468576B1 FR2468576B1 FR8100143A FR8100143A FR2468576B1 FR 2468576 B1 FR2468576 B1 FR 2468576B1 FR 8100143 A FR8100143 A FR 8100143A FR 8100143 A FR8100143 A FR 8100143A FR 2468576 B1 FR2468576 B1 FR 2468576B1
- Authority
- FR
- France
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/26—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C43/00—Ethers; Compounds having groups, groups or groups
- C07C43/02—Ethers
- C07C43/20—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring
- C07C43/225—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring containing halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/45—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation
- C07C45/46—Friedel-Crafts reactions
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/63—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by introduction of halogen; by substitution of halogen atoms by other halogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
- C07C49/84—Ketones containing a keto group bound to a six-membered aromatic ring containing ether groups, groups, groups, or groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C65/00—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C65/21—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing ether groups, groups, groups, or groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Hydrogenated Pyridines (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Catalysts (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US2133179A | 1979-03-19 | 1979-03-19 | |
| US2133279A | 1979-03-19 | 1979-03-19 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FR2468576A1 FR2468576A1 (fr) | 1981-05-08 |
| FR2468576B1 true FR2468576B1 (de) | 1983-01-21 |
Family
ID=26694559
Family Applications (7)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR8006019A Granted FR2454438A1 (fr) | 1979-03-19 | 1980-03-18 | Procede de preparation de 2,5-bis(2,2,2-trifluorethoxy)-n-(2-piperidylmethyl)benzamide |
| FR8100145A Granted FR2468591A1 (fr) | 1979-03-19 | 1981-01-07 | Procede de preparation de 2,5-bis(2,2,2-trifluorethoxy)-n-(2-piperidylmethyl)benzamide a partir du chlorure de l'acide 2,5-bis(2,2,2-trifluorethoxy)benzoique |
| FR8100142A Granted FR2468571A1 (fr) | 1979-03-19 | 1981-01-07 | 2,5-bis (2,2,2-trifluorethoxy)-a,a,a-trichloracetophenone, procede pour sa preparation et son application a la fabrication de medicament connu |
| FR8100140A Granted FR2468569A1 (fr) | 1979-03-19 | 1981-01-07 | 2,5-bis (2,2,2-trifluorethoxy) acetophenone, procede pour sa preparation et son application a la fabrication de medicament connu |
| FR8100141A Granted FR2468570A1 (fr) | 1979-03-19 | 1981-01-07 | 2,5-bis (2,2,2-trifluorethoxy)-a, a-dichloracetophenone, procede pour sa preparation et son application a la fabrication de medicament connu |
| FR8100143A Granted FR2468576A1 (fr) | 1979-03-19 | 1981-01-07 | Procede de preparation de l'acide 2,5-bis (2,2,2-trifluorethoxy)-benzoique |
| FR8100144A Granted FR2468590A1 (fr) | 1979-03-19 | 1981-01-07 | Procede de preparation de 2,5-bis (2,2,2-trifluorethoxy)-n-(2-piperidylmethyl) benzamide a partir de 2,5-bis (2,2,2-trifluorethoxy)-a, a, a-trichloracetophenone |
Family Applications Before (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR8006019A Granted FR2454438A1 (fr) | 1979-03-19 | 1980-03-18 | Procede de preparation de 2,5-bis(2,2,2-trifluorethoxy)-n-(2-piperidylmethyl)benzamide |
| FR8100145A Granted FR2468591A1 (fr) | 1979-03-19 | 1981-01-07 | Procede de preparation de 2,5-bis(2,2,2-trifluorethoxy)-n-(2-piperidylmethyl)benzamide a partir du chlorure de l'acide 2,5-bis(2,2,2-trifluorethoxy)benzoique |
| FR8100142A Granted FR2468571A1 (fr) | 1979-03-19 | 1981-01-07 | 2,5-bis (2,2,2-trifluorethoxy)-a,a,a-trichloracetophenone, procede pour sa preparation et son application a la fabrication de medicament connu |
| FR8100140A Granted FR2468569A1 (fr) | 1979-03-19 | 1981-01-07 | 2,5-bis (2,2,2-trifluorethoxy) acetophenone, procede pour sa preparation et son application a la fabrication de medicament connu |
| FR8100141A Granted FR2468570A1 (fr) | 1979-03-19 | 1981-01-07 | 2,5-bis (2,2,2-trifluorethoxy)-a, a-dichloracetophenone, procede pour sa preparation et son application a la fabrication de medicament connu |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR8100144A Granted FR2468590A1 (fr) | 1979-03-19 | 1981-01-07 | Procede de preparation de 2,5-bis (2,2,2-trifluorethoxy)-n-(2-piperidylmethyl) benzamide a partir de 2,5-bis (2,2,2-trifluorethoxy)-a, a, a-trichloracetophenone |
Country Status (14)
| Country | Link |
|---|---|
| JP (8) | JPH01125344A (de) |
| CA (1) | CA1137486A (de) |
| CH (1) | CH643829A5 (de) |
| DE (1) | DE3010195A1 (de) |
| DK (3) | DK167062B1 (de) |
| ES (1) | ES8104227A1 (de) |
| FR (7) | FR2454438A1 (de) |
| GB (2) | GB2045760B (de) |
| IE (1) | IE49558B1 (de) |
| IL (1) | IL59623A (de) |
| IT (1) | IT1195262B (de) |
| NL (1) | NL191486C (de) |
| PT (1) | PT70967A (de) |
| SE (5) | SE447992B (de) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2519980A1 (fr) * | 1982-01-21 | 1983-07-22 | Rhone Poulenc Spec Chim | Procede de sulfonylation d'halogeno ou trihalogenomethylbenzenes |
| FR2519979A1 (fr) * | 1982-01-21 | 1983-07-22 | Rhone Poulenc Spec Chim | Procede de preparation de trifluoromethoxy ou trifluoromethylthiophenylsulfones |
| FR2519974A1 (fr) * | 1982-01-21 | 1983-07-22 | Rhone Poulenc Spec Chim | Procede d'acylation d'halogeno ou trihalogenomethylbenzenes |
| FR2519975A1 (fr) * | 1982-01-21 | 1983-07-22 | Rhone Poulenc Spec Chim | Procede de preparation de trifluoromethoxy ou trifluoromethylthiophenylcetones |
| FR2525588A1 (fr) * | 1982-04-22 | 1983-10-28 | Rhone Poulenc Spec Chim | Procede de preparation de phenylcetones a partir d'halogeno ou trihalogenomethylbenzenes et de composes aliphatiques ou aromatiques trihalogenomethyles |
| EP0175188A1 (de) * | 1984-09-11 | 1986-03-26 | Nihon Tokushu Noyaku Seizo K.K. | Carbamoylimidazol-Derivate |
| US4675448A (en) * | 1985-02-13 | 1987-06-23 | Ethyl Corporation | Chlorination process |
| FR2579591B1 (fr) * | 1985-03-29 | 1988-10-14 | Rhone Poulenc Spec Chim | Procede de preparation de derives pentafluoroethoxy et pentafluoroethylthiobenzeniques |
| FR2579594B1 (fr) * | 1985-03-29 | 1987-06-05 | Rhone Poulenc Spec Chim | Procede de preparation de trifluoroethoxy ou trifluoroethylthiobenzenes |
| DE3786037T2 (de) * | 1986-04-25 | 1993-11-25 | Abbott Lab | Tracer zur Benutzung in immunologischen Fluoreszenz-Polarisationsverfahren zum Nachweis von Flecainid. |
| NZ219913A (en) * | 1986-04-25 | 1990-08-28 | Riker Laboratories Inc | Various flecainide derivatives and antibodies raised thereto |
| DE3644798A1 (de) * | 1986-12-31 | 1988-07-14 | Hoechst Ag | Neue nitrohaloalkoxybenzole, verfahren zu ihrer herstellung und ihre verwendung |
| FR2640262B1 (fr) * | 1988-12-14 | 1991-05-31 | Rhone Poulenc Chimie | Procede de preparation de cetones aryliques trifluoroethoxylees |
| US6316627B1 (en) * | 1997-04-21 | 2001-11-13 | Fine Tech Ltd. | Process for the preparation of flecainide |
| IL120715A (en) * | 1997-04-21 | 2000-07-16 | Finetech Ltd | Process for the preparation of (2,2,2,-trifluoroethoxy)benzoic acids |
| IL121288A (en) | 1997-07-11 | 2000-10-31 | Finetech Ltd | Process and a novel intermediate for the preparation of flecainide |
| US7196197B2 (en) | 2003-09-17 | 2007-03-27 | Apotex Pharmachem Inc. | Process for the preparation of Flecainide, its pharmaceutically acceptable salts and important intermediates thereof |
| JP4894226B2 (ja) * | 2005-10-31 | 2012-03-14 | Ｄｉｃ株式会社 | ハイドロキノン骨格を有する含フッ素液晶化合物の製造方法 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3539642A (en) * | 1967-07-19 | 1970-11-10 | Geigy Chem Corp | 2-phenyl-2-(1-naphthyl)acetamides |
| US3772304A (en) * | 1969-10-30 | 1973-11-13 | Hoffmann La Roche | 4-hydroxy-isoquinolines and processes for their preparation |
| US3719687A (en) * | 1970-07-22 | 1973-03-06 | Riker Laboratories Inc | N-(2-dialkylaminoalkylene)amides of 1,1-dihydroperfluoroalkoxy-substituted aryl acids and salts thereof |
| US3655728A (en) | 1970-07-22 | 1972-04-11 | Riker Laboratories Inc | N-(2 - dialkylaminoalkylene)-esters of fluoroalkoxy-substituted aryl carboxylic acid and salts thereof |
| US3967949A (en) * | 1973-06-18 | 1976-07-06 | Eli Lilly And Company | Fluoroalkoxyphenyl-substituted nitrogen heterocycles as plant stunting agents |
| US4169108A (en) * | 1973-08-16 | 1979-09-25 | Sterling Drug Inc. | 5(OR 6)-[(Substituted-amino)alkyl]-2,3-naphthalenediols |
| US4005209A (en) * | 1974-04-01 | 1977-01-25 | Riker Laboratories, Inc. | Antiarrhythmic method utilizing fluoroalkoxy-N-piperidyl and pyridyl benzamides |
| US3900481A (en) * | 1974-04-01 | 1975-08-19 | Riker Laboratories Inc | Derivatives of pyrrolidine and piperidine |
| US4013670A (en) * | 1974-04-01 | 1977-03-22 | Riker Laboratories, Inc. | Derivatives of pyrrolidine and piperidine |
| IL49803A (en) * | 1975-06-28 | 1979-11-30 | Fisons Ltd | Preparation of pyrogallol |
| DE2616478C2 (de) * | 1976-04-14 | 1986-05-22 | Brickl, Rolf, Dr., 7951 Warthausen | Fluoracylresorcine enthaltende Arzneimittel, Biocide und Kosmetika |
| JPS6023656B2 (ja) * | 1976-09-02 | 1985-06-08 | 川研フアインケミカル株式会社 | アルコキシ芳香族化合物の製造方法 |
| US4071524A (en) * | 1976-11-08 | 1978-01-31 | Riker Laboratories, Inc. | Derivatives of urea |
| US4097481A (en) * | 1976-11-08 | 1978-06-27 | Riker Laboratories, Inc. | Tertiary amide derivatives of pyrrolidine and piperidine |
-
0
- GB GB8214964A patent/GB2097000B/en not_active Expired
-
1980
- 1980-03-04 CA CA000346919A patent/CA1137486A/en not_active Expired
- 1980-03-14 DK DK112180A patent/DK167062B1/da not_active IP Right Cessation
- 1980-03-14 SE SE8002003A patent/SE447992B/sv not_active IP Right Cessation
- 1980-03-14 IL IL59623A patent/IL59623A/xx unknown
- 1980-03-16 NL NL8001551A patent/NL191486C/xx not_active IP Right Cessation
- 1980-03-17 ES ES489629A patent/ES8104227A1/es not_active Expired
- 1980-03-17 DE DE19803010195 patent/DE3010195A1/de active Granted
- 1980-03-18 GB GB8009041A patent/GB2045760B/en not_active Expired
- 1980-03-18 FR FR8006019A patent/FR2454438A1/fr active Granted
- 1980-03-18 CH CH212880A patent/CH643829A5/de not_active IP Right Cessation
- 1980-03-18 IE IE549/80A patent/IE49558B1/en not_active IP Right Cessation
- 1980-03-18 PT PT70967A patent/PT70967A/pt active IP Right Revival
- 1980-03-18 IT IT20746/80A patent/IT1195262B/it active Protection Beyond IP Right Term
-
1981
- 1981-01-07 FR FR8100145A patent/FR2468591A1/fr active Granted
- 1981-01-07 FR FR8100142A patent/FR2468571A1/fr active Granted
- 1981-01-07 FR FR8100140A patent/FR2468569A1/fr active Granted
- 1981-01-07 FR FR8100141A patent/FR2468570A1/fr active Granted
- 1981-01-07 FR FR8100143A patent/FR2468576A1/fr active Granted
- 1981-01-07 FR FR8100144A patent/FR2468590A1/fr active Granted
-
1984
- 1984-03-21 SE SE8401555A patent/SE463260B/sv not_active IP Right Cessation
- 1984-03-21 SE SE8401554A patent/SE447993B/sv not_active IP Right Cessation
-
1988
- 1988-06-01 JP JP63135370A patent/JPH01125344A/ja active Granted
- 1988-06-01 JP JP63135367A patent/JPH01125341A/ja active Granted
- 1988-06-01 JP JP63135364A patent/JPH01104043A/ja active Granted
- 1988-06-01 JP JP63135366A patent/JPH01125339A/ja active Granted
- 1988-06-01 JP JP63135369A patent/JPH01125343A/ja active Granted
- 1988-06-01 JP JP63135368A patent/JPH01125342A/ja active Granted
- 1988-06-01 JP JP63135363A patent/JPH01104045A/ja active Granted
- 1988-06-01 JP JP63135365A patent/JPH01104044A/ja active Granted
-
1989
- 1989-04-27 SE SE8901533A patent/SE463419B/sv not_active IP Right Cessation
- 1989-04-27 SE SE8901532A patent/SE463418B/sv not_active IP Right Cessation
-
1990
- 1990-05-17 DK DK122290A patent/DK164857C/da not_active IP Right Cessation
-
1991
- 1991-04-30 DK DK91798A patent/DK79891D0/da unknown
Also Published As
Similar Documents
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| CC | Supplementary protection certificate (spc) laid open to the public (law of 25 june 1990) |
Free format text: 92C0285, 920525 |
|
| CB | Supplementary protection certificate (spc) granted (law of 25 june 1990) |
Free format text: 92C0285, 810107 |
|
| CL | Concession to grant licences | ||
| CA | Change of address |
Spc suppl protection certif: 92C0285 |
|
| CL | Concession to grant licences |
Spc suppl protection certif: 92C0285 |
|
| TP | Transmission of property |
Spc suppl protection certif: 92C0285 |