FR2331375A1 - Procede pour l'obtention de preparations avec liberation reglee d'un principe actif - Google Patents

Procede pour l'obtention de preparations avec liberation reglee d'un principe actif

Info

Publication number
FR2331375A1
FR2331375A1 FR7634515A FR7634515A FR2331375A1 FR 2331375 A1 FR2331375 A1 FR 2331375A1 FR 7634515 A FR7634515 A FR 7634515A FR 7634515 A FR7634515 A FR 7634515A FR 2331375 A1 FR2331375 A1 FR 2331375A1
Authority
FR
France
Prior art keywords
procedure
active principle
regulated release
obtaining preparations
preparations
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7634515A
Other languages
English (en)
Other versions
FR2331375B1 (fr
Inventor
Conny Borje Bogentoft
Curt Henry Appelgren
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hassle AB
Original Assignee
Hassle AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hassle AB filed Critical Hassle AB
Publication of FR2331375A1 publication Critical patent/FR2331375A1/fr
Application granted granted Critical
Publication of FR2331375B1 publication Critical patent/FR2331375B1/fr
Granted legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
FR7634515A 1975-11-17 1976-11-16 Procede pour l'obtention de preparations avec liberation reglee d'un principe actif Granted FR2331375A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE7512883A SE418247B (sv) 1975-11-17 1975-11-17 Sett att framstella kroppar med reglerad frigoring av en aktiv komponent

Publications (2)

Publication Number Publication Date
FR2331375A1 true FR2331375A1 (fr) 1977-06-10
FR2331375B1 FR2331375B1 (fr) 1981-12-31

Family

ID=20326096

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7634515A Granted FR2331375A1 (fr) 1975-11-17 1976-11-16 Procede pour l'obtention de preparations avec liberation reglee d'un principe actif

Country Status (24)

Country Link
US (2) US4289795A (fr)
JP (1) JPS5919526B2 (fr)
AT (1) AT354636B (fr)
AU (1) AU508266B2 (fr)
BE (1) BE848406A (fr)
CA (1) CA1075031A (fr)
CS (1) CS207374B2 (fr)
DD (1) DD128170A5 (fr)
DE (1) DE2651176A1 (fr)
DK (1) DK146213C (fr)
FI (1) FI62462C (fr)
FR (1) FR2331375A1 (fr)
GB (1) GB1560841A (fr)
HK (1) HK14683A (fr)
HU (1) HU173461B (fr)
IE (1) IE44353B1 (fr)
LU (1) LU76215A1 (fr)
MY (1) MY8400019A (fr)
NL (1) NL187259C (fr)
NO (1) NO144763C (fr)
NZ (1) NZ182621A (fr)
SE (1) SE418247B (fr)
SU (1) SU1326180A3 (fr)
ZA (1) ZA766669B (fr)

Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0013263A2 (fr) * 1978-12-05 1980-07-09 Aktiebolaget Hässle Préparation pharmaceutique comprenant un glycoside cardiaque combiné à un polymère et procédé pour sa fabrication
EP0013262A2 (fr) * 1978-12-22 1980-07-09 Aktiebolaget Hässle Préparation pharmaceutique comprenant un glycoside cardiaque ayant un enrobage polymère et procédé pour sa fabrication
FR2470600A2 (fr) * 1979-12-07 1981-06-12 Panoz Donald Nouvelle forme galenique d'administration de medicaments par voie orale, a liberation programmee
EP0111144A1 (fr) * 1982-11-01 1984-06-20 Merrell Dow Pharmaceuticals Inc. Formes de dosage solides à libération contrôlée présentant une répartition inégale de la substance active
EP0294493A1 (fr) * 1986-12-25 1988-12-14 Teysan Pharmaceuticals Co., Ltd. Granule a dissolution lente et granule composite a effet persistant prepare a partir du premier granule
EP0297650A1 (fr) * 1987-06-26 1989-01-04 Duphar International Research B.V Compositions avec une délivrance contrôlée d'ordre zéro et méthode pour leur préparation
EP0299211A1 (fr) * 1987-06-24 1989-01-18 Bayer Ag Comprimé enrobé en DHP
WO1990001932A1 (fr) * 1988-08-25 1990-03-08 Himedics, Inc. Granules microencapsules contenant de l'amoxicilline
WO1990001926A1 (fr) * 1988-08-19 1990-03-08 Himedics, Inc. Granules microencapsules contenant de l'erythromycine
US4971805A (en) * 1987-12-23 1990-11-20 Teysan Pharmaceuticals Co., Ltd. Slow-releasing granules and long acting mixed granules comprising the same

Families Citing this family (84)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE48715B1 (en) * 1978-12-22 1985-05-01 Elan Corp Plc New galencial forms for administration of medicaments by oral route,with programmed release and processes for preparing same
FR2470599A1 (fr) * 1979-12-07 1981-06-12 Panoz Donald Perfectionnements apportes aux procedes de preparation de formes galeniques a action retard et a liberation programmee et formes galeniques de medicaments ainsi obtenus
JPS5911563B2 (ja) * 1980-02-27 1984-03-16 日本原子力研究所 多層構造の徐放性複合体を製造する方法
ATE14379T1 (de) * 1981-04-27 1985-08-15 Haessle Ab Pharmazeutisches praeparat.
JPS5858146A (ja) * 1981-10-05 1983-04-06 Tanabe Seiyaku Co Ltd 速放性マイクロカプセル
US4370313A (en) * 1981-10-26 1983-01-25 Eaton Laboratories, Inc. Nitrofurantoin dosage form
EP0094123A3 (fr) * 1982-05-06 1984-07-25 THE PROCTER & GAMBLE COMPANY Granulés thérapeutiques
EP0094116A3 (fr) * 1982-05-06 1984-08-01 The Procter & Gamble Company Granulés thérapeutiques
EP0094117A3 (fr) * 1982-05-06 1984-08-01 The Procter & Gamble Company Granulés thérapeutiques
US4415547A (en) * 1982-06-14 1983-11-15 Sterling Drug Inc. Sustained-release pharmaceutical tablet and process for preparation thereof
US4508702A (en) * 1982-06-14 1985-04-02 Key Pharmaceuticals, Inc. Sustained release aspirin
WO1984000004A1 (fr) * 1982-06-14 1984-01-05 Key Pharma Aspirine a liberation entretenue
US4443428A (en) * 1982-06-21 1984-04-17 Euroceltique, S.A. Extended action controlled release compositions
US4634587A (en) * 1982-07-09 1987-01-06 Key Pharmaceuticals, Inc. Sustained release quinidine dosage form
WO1984000295A1 (fr) * 1982-07-09 1984-02-02 Key Pharma Forme de dosage de quinidine a liberation entretenue
CA1223172A (fr) * 1982-09-23 1987-06-23 Sidney Melamed Microbicide solide encapsule
US5283060A (en) * 1982-09-29 1994-02-01 Shieh Tsuong R Bacillus-containing pesticide granules
US4461759A (en) * 1983-01-03 1984-07-24 Verex Laboratories, Inc. Constant release rate solid oral dosage formulations of veropamil
JPS59155309A (ja) * 1983-02-22 1984-09-04 Teijin Ltd 活性型ビタミンｄ↓３類組成物
DE3306250A1 (de) * 1983-02-23 1984-08-23 Basf Ag, 6700 Ludwigshafen Sphaerische einkristalle fuer pharmazeutische zwecke
DE3315272C2 (de) * 1983-04-27 1986-03-27 Lohmann Gmbh & Co Kg, 5450 Neuwied Pharmazeutisches Produkt und Verfahren zu seiner Herstellung
GB2141023B (en) * 1983-06-06 1986-09-03 Robins Co Inc A H Delayed release formulations
US4555399A (en) * 1983-11-18 1985-11-26 Key Pharmaceuticals, Inc. Aspirin tablet
US4708867A (en) * 1983-12-19 1987-11-24 Key Pharmaceuticals, Inc. Minipellets
SE457505B (sv) * 1984-01-10 1989-01-09 Lejus Medical Ab Laminatbelagd oral farmaceutisk komposition och foerfarande foer dess framstaellning
DE3403329A1 (de) * 1984-02-01 1985-08-01 Horst Dr. 4019 Monheim Zerbe Pharmazeutisches produkt in form von pellets mit kontinuierlicher, verzoegerter wirkstoffabgabe
US4600645A (en) * 1985-01-31 1986-07-15 Warner-Lambert Company Process for treating dosage forms
US4693886A (en) * 1985-04-22 1987-09-15 Alza Corporation Osmotic device with inert core
SE458576B (sv) * 1985-06-20 1989-04-17 Lejus Medical Ab Foerfarande foer framstaellning av en guar-gum produkt
SE455836B (sv) * 1985-10-11 1988-08-15 Haessle Ab Beredning med kontrollerad frisettning innehallande ett salt av metoprolol samt metod for framstellning av denna beredning
SE450087B (sv) * 1985-10-11 1987-06-09 Haessle Ab Korn med kontrollerad frisettning av farmaceutiskt aktiva emnen som anbringats teckande pa ett kompakt olosligt kernmaterial
US4898733A (en) * 1985-11-04 1990-02-06 International Minerals & Chemical Corp. Layered, compression molded device for the sustained release of a beneficial agent
EP0225085A1 (fr) * 1985-11-13 1987-06-10 ELAN CORPORATION, Plc Formulation pharmaceutique à absorption contrôlée
US5019302A (en) * 1986-03-12 1991-05-28 Washington University Technology Associates, Inc. Method for granulation
US5100592A (en) * 1986-03-12 1992-03-31 Washington University Technology Associated, Inc. Method and apparatus for granulation and granulated product
US4861598A (en) * 1986-07-18 1989-08-29 Euroceltique, S.A. Controlled release bases for pharmaceuticals
US5624683A (en) * 1986-08-06 1997-04-29 Eisai Co., Ltd. Sustained-release multi-granule tablet
IT1200217B (it) * 1986-09-30 1989-01-05 Valducci Roberto Membrana per uso farmaceutico ed industriale
US4800087A (en) * 1986-11-24 1989-01-24 Mehta Atul M Taste-masked pharmaceutical compositions
US5026560A (en) * 1987-01-29 1991-06-25 Takeda Chemical Industries, Ltd. Spherical granules having core and their production
GB8702411D0 (en) * 1987-02-03 1987-03-11 Zyma Sa Swellable pellets
HU197519B (en) * 1987-06-22 1989-04-28 Biogal Gyogyszergyar Process for producing medicine form capable for penetrating through epidermis and suitable for intaking the agent through epidermis by kinetics of zero-grade
US5219575A (en) * 1987-06-26 1993-06-15 Duphar International Research B.V. Compositions with controlled zero-order delivery rate and method of preparing these compositions
DE3721721C1 (de) * 1987-07-01 1988-06-09 Hoechst Ag Verfahren zur Umhuellung von Granulaten
IT1231410B (it) * 1987-09-22 1991-12-04 Cooperativa Farmaceutica Composizione farmaceutica antiinfiammatoria ad effetto prolungato per uso topico
SE8703881D0 (sv) * 1987-10-08 1987-10-08 Haessle Ab New pharmaceutical preparation
US4971796A (en) * 1988-10-05 1990-11-20 Sjogren Robert D Slow release pest control granule composition
DE3838094A1 (de) * 1988-11-10 1990-05-17 Nordmark Arzneimittel Gmbh Feste pharmazeutische retardform
EP0376331A3 (fr) * 1988-12-29 1991-03-13 Asahi Kogaku Kogyo Kabushiki Kaisha Granules pour la délivrance à faible vitesse d'un médicament et leur procédé de fabrication
US5032406A (en) * 1989-02-21 1991-07-16 Norwich Eaton Pharmaceuticals, Inc. Dual-action tablet
US5084278A (en) * 1989-06-02 1992-01-28 Nortec Development Associates, Inc. Taste-masked pharmaceutical compositions
DE3918801A1 (de) * 1989-06-06 1991-05-08 Schmidt Walter Praeparat zur geregelten wirkstoffabgabe und verfahren zu dessen herstellung
JP2813809B2 (ja) * 1989-06-19 1998-10-22 武田薬品工業株式会社 有核顆粒製剤およびその製造法
US4966770A (en) * 1989-07-26 1990-10-30 Himedics, Inc. Prednisone microencapsulated granules
US5707652A (en) * 1990-12-04 1998-01-13 State Of Oregon Methods of treating circadian rhythm phase disorders
US6638963B1 (en) 1990-12-04 2003-10-28 Oregon Health And Science University Methods for treating circadian rhythm disorders
US5153002A (en) * 1991-03-04 1992-10-06 University Of Montreal Biocompatible gradient controlled release implant
FI93924C (fi) * 1991-09-17 1995-06-26 Martti Lauri Antero Marvola Menetelmä säädellysti lääkeainetta vapauttavan valmisteen valmistamiseksi
ZA933725B (en) * 1992-05-28 1993-12-15 Elan Corp Plc Tablet formulation
US5662935A (en) * 1992-12-23 1997-09-02 Saitec S.R.L. Process for preparing controlled release pharmaceutical forms and the forms thus obtained
IT1274879B (it) * 1994-08-03 1997-07-25 Saitec Srl Apparecchio e metodo per preparare forme farmaceutiche solide a rilascio controllato del principio attivo.
DE4446468A1 (de) * 1994-12-23 1996-06-27 Basf Ag Verfahren zur Herstellung von umhüllten Tabletten
US5762963A (en) * 1995-06-07 1998-06-09 Emory University Method and compositions for controlling oral and pharyngeal pain using capsaicinoids
US5773031A (en) * 1996-02-27 1998-06-30 L. Perrigo Company Acetaminophen sustained-release formulation
GB9703673D0 (en) * 1997-02-21 1997-04-09 Bradford Particle Design Ltd Method and apparatus for the formation of particles
RU2271196C2 (ru) * 1999-06-04 2006-03-10 Элзэ Копэрейшн Имплантируемая композиция (варианты) и способ ее приготовления
EP1949890A3 (fr) 1999-06-04 2011-05-18 ALZA Corporation Compositions de gel implantables et procédé de fabrication
DK1276470T3 (da) 2000-04-20 2007-06-18 Novartis Ag Smagskaskerende overtrækssammensætning
KR100402053B1 (ko) * 2000-09-28 2003-10-17 한국화학연구원 항생제의 서방성 임플란트 제제
GB0027357D0 (en) * 2000-11-09 2000-12-27 Bradford Particle Design Plc Particle formation methods and their products
CA2464653C (fr) 2001-10-29 2011-10-18 Therics, Inc. Systeme d'elaboration de formes pharmaceutiques a liberation controlee, du type forme pharmaceutique a profil de liberation d'ordre zero elaboree en impression tridimensionnelle
US6723348B2 (en) * 2001-11-16 2004-04-20 Ethypharm Orodispersible tablets containing fexofenadine
GB0216562D0 (en) 2002-04-25 2002-08-28 Bradford Particle Design Ltd Particulate materials
US9339459B2 (en) 2003-04-24 2016-05-17 Nektar Therapeutics Particulate materials
GB0228421D0 (en) * 2002-12-05 2003-01-08 Exosect Ltd Lipid carriers
DE10260919A1 (de) * 2002-12-20 2004-07-01 Röhm GmbH & Co. KG Verfahren zur Herstellung von überzogenen Arzneiformen und Nahrungsergänzungsmitteln mit Konzentrationsgradienten im Überzug
GB0310636D0 (en) * 2003-05-08 2003-06-11 Nektar Therapeutics Uk Ltd Particulate materials
US7354601B2 (en) 2003-05-08 2008-04-08 Walker Stephen E Particulate materials
CA2556943A1 (fr) * 2004-03-31 2005-10-20 Eid Parry (India) Limited Preparation granulaire amelioree d'extrait de graines de neem et procede associe
US20050244465A1 (en) * 2004-04-30 2005-11-03 Allergan, Inc. Drug delivery systems and methods for treatment of an eye
US20060147516A1 (en) * 2005-01-06 2006-07-06 Cima Labs Inc. Taste masking system for alprazolam
MX350838B (es) 2011-02-11 2017-09-18 Grain Proc Corporation * Composicion de sal.
CA2936741C (fr) 2014-10-31 2018-11-06 Purdue Pharma Methodes et compositions destinees au traitement du trouble de deficit d'attention
US10722473B2 (en) 2018-11-19 2020-07-28 Purdue Pharma L.P. Methods and compositions particularly for treatment of attention deficit disorder

Citations (3)

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Publication number Priority date Publication date Assignee Title
FR1588833A (fr) * 1967-06-28 1970-03-16
FR2160410A1 (fr) * 1971-11-20 1973-06-29 Schering Ag
FR2162628A1 (fr) * 1971-12-09 1973-07-20 Upjohn Co

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US2928770A (en) * 1958-11-28 1960-03-15 Frank M Bardani Sustained action pill
BE623704A (fr) * 1961-10-20
US3383283A (en) * 1964-01-24 1968-05-14 Merck & Co Inc Medicinal pellets coated with overlapping porous fatty acid leaflet layers
FR1545612A (fr) * 1967-06-15 1968-11-15 Dausse Lab Procédé de fabrication de comprimés
DK123806B (da) * 1970-06-08 1972-08-07 Pharmacia As Fremgangsmåde til fremstilling af tabletter eller piller med langsom afgivelse af et aktivt stof.

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1588833A (fr) * 1967-06-28 1970-03-16
FR2160410A1 (fr) * 1971-11-20 1973-06-29 Schering Ag
FR2162628A1 (fr) * 1971-12-09 1973-07-20 Upjohn Co

Cited By (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0013263A2 (fr) * 1978-12-05 1980-07-09 Aktiebolaget Hässle Préparation pharmaceutique comprenant un glycoside cardiaque combiné à un polymère et procédé pour sa fabrication
EP0013263A3 (en) * 1978-12-05 1981-05-27 Aktiebolaget Hassle A pharmaceutical preparation comprising a cardiac glycoside in combination with a polymer, and a process for preparation thereof
EP0013262A2 (fr) * 1978-12-22 1980-07-09 Aktiebolaget Hässle Préparation pharmaceutique comprenant un glycoside cardiaque ayant un enrobage polymère et procédé pour sa fabrication
EP0013262A3 (en) * 1978-12-22 1981-05-27 Aktiebolaget Hassle A pharmaceutical preparation comprising a cardiac glycoside with a polymer coating, and a process for preparation thereof
FR2470600A2 (fr) * 1979-12-07 1981-06-12 Panoz Donald Nouvelle forme galenique d'administration de medicaments par voie orale, a liberation programmee
EP0111144A1 (fr) * 1982-11-01 1984-06-20 Merrell Dow Pharmaceuticals Inc. Formes de dosage solides à libération contrôlée présentant une répartition inégale de la substance active
EP0294493A1 (fr) * 1986-12-25 1988-12-14 Teysan Pharmaceuticals Co., Ltd. Granule a dissolution lente et granule composite a effet persistant prepare a partir du premier granule
EP0294493A4 (fr) * 1986-12-25 1989-07-24 Teysan Pharmaceuticals Co Ltd Granule a dissolution lente et granule composite a effet persistant prepare a partir du premier granule.
EP0299211A1 (fr) * 1987-06-24 1989-01-18 Bayer Ag Comprimé enrobé en DHP
US4892741A (en) * 1987-06-24 1990-01-09 Bayer Aktiengesellschaft Press coated DHP tablets
EP0297650A1 (fr) * 1987-06-26 1989-01-04 Duphar International Research B.V Compositions avec une délivrance contrôlée d'ordre zéro et méthode pour leur préparation
US4971805A (en) * 1987-12-23 1990-11-20 Teysan Pharmaceuticals Co., Ltd. Slow-releasing granules and long acting mixed granules comprising the same
WO1990001926A1 (fr) * 1988-08-19 1990-03-08 Himedics, Inc. Granules microencapsules contenant de l'erythromycine
US4925675A (en) * 1988-08-19 1990-05-15 Himedics, Inc. Erythromycin microencapsulated granules
WO1990001932A1 (fr) * 1988-08-25 1990-03-08 Himedics, Inc. Granules microencapsules contenant de l'amoxicilline
US4925674A (en) * 1988-08-25 1990-05-15 Himedics, Inc. Amoxicillin microencapsulated granules

Also Published As

Publication number Publication date
FR2331375B1 (fr) 1981-12-31
HK14683A (en) 1983-05-13
IE44353B1 (en) 1981-11-04
JPS5283921A (en) 1977-07-13
DE2651176A1 (de) 1977-05-18
DK146213C (da) 1984-01-16
NL187259C (nl) 1991-08-01
JPS5919526B2 (ja) 1984-05-07
AU508266B2 (en) 1980-03-13
US4341759A (en) 1982-07-27
BE848406A (fr) 1977-05-17
NO763807L (fr) 1977-05-20
SE7512883L (sv) 1977-05-18
NL187259B (nl) 1991-03-01
DE2651176C2 (fr) 1987-06-11
NO144763C (no) 1981-11-04
ZA766669B (en) 1977-10-26
CS207374B2 (en) 1981-07-31
NO144763B (no) 1981-07-27
IE44353L (en) 1977-05-17
US4289795A (en) 1981-09-15
DK146213B (da) 1983-08-01
FI62462C (fi) 1983-01-10
LU76215A1 (fr) 1977-06-06
AT354636B (de) 1979-01-25
SU1326180A3 (ru) 1987-07-23
MY8400019A (en) 1984-12-31
NZ182621A (en) 1978-12-18
FI62462B (fi) 1982-09-30
DK513476A (da) 1977-05-18
GB1560841A (en) 1980-02-13
FI763257A (fr) 1977-05-18
HU173461B (hu) 1979-05-28
CA1075031A (fr) 1980-04-08
DD128170A5 (de) 1977-11-02
ATA850576A (de) 1979-06-15
AU1961776A (en) 1978-05-25
NL7612728A (nl) 1977-05-20
SE418247B (sv) 1981-05-18

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Legal Events

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