FR2262525A1 - - Google Patents

Info

Publication number
FR2262525A1
FR2262525A1 FR7506414A FR7506414A FR2262525A1 FR 2262525 A1 FR2262525 A1 FR 2262525A1 FR 7506414 A FR7506414 A FR 7506414A FR 7506414 A FR7506414 A FR 7506414A FR 2262525 A1 FR2262525 A1 FR 2262525A1
Authority
FR
France
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7506414A
Other versions
FR2262525B1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
CH Boehringer Sohn AG and Co KG
Original Assignee
CH Boehringer Sohn AG and Co KG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE2410030A external-priority patent/DE2410030C3/de
Priority claimed from DE2435041A external-priority patent/DE2435041C3/de
Priority claimed from DE19742445430 external-priority patent/DE2445430B2/de
Priority claimed from DE2460776A external-priority patent/DE2460776C2/de
Application filed by CH Boehringer Sohn AG and Co KG filed Critical CH Boehringer Sohn AG and Co KG
Publication of FR2262525A1 publication Critical patent/FR2262525A1/fr
Application granted granted Critical
Publication of FR2262525B1 publication Critical patent/FR2262525B1/fr
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/30—Hetero atoms other than halogen
    • C07D333/36—Nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D495/14—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
FR7506414A 1974-03-02 1975-02-28 Expired FR2262525B1 (fr)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DE2410030A DE2410030C3 (de) 1974-03-02 1974-03-02 8-Brom-6-phenyl-4H-s-triazolo[3,4-c]thieno[2,3-e]1,4-diazepine, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Zusammensetzungen
DE2435041A DE2435041C3 (de) 1974-07-20 1974-07-20 8-Substituierte 6-Aryl-4H-s-triazolo [3,4c] thieno [23e] 1,4-diazepine, Verfahren zu ihrer Herstellung, ihre Verwendung in Arzneimitteln und diese enthaltende pharmazeutische Präparate
DE19742445430 DE2445430B2 (de) 1974-07-20 1974-09-24 1 - substituierte 6-aryl-4h-striazolo eckige klammer auf 3,4c eckige klammer zu thieno-eckige klammer auf 2,3e eckige klammer zu 1,4-diazepine, verfahren zu ihrer herstellung und diese enthaltende arzneimittel
DE2460776A DE2460776C2 (de) 1974-07-20 1974-12-21 1-substituierte 6-Aryl-4H-s-triazolo-(3,4c)-thieno-(2,3e)-1,4-diazepine, Verfahren zu ihrer Herstellung, diese enthaltende pharmazeutische Präparate sowie Zwischenprodukte und Verfahren zur Herstellung dieser Zwischenprodukte

Publications (2)

Publication Number Publication Date
FR2262525A1 true FR2262525A1 (fr) 1975-09-26
FR2262525B1 FR2262525B1 (fr) 1978-08-18

Family

ID=27431816

Family Applications (3)

Application Number Title Priority Date Filing Date
FR7506414A Expired FR2262525B1 (fr) 1974-03-02 1975-02-28
FR7601563A Granted FR2287449A1 (fr) 1974-03-02 1976-01-21 Nouvelles 5-aryl-2(subst.)-carbonylhydrazino-3h-(2,3-e)-thieno-1,4-diazepines et procede pour leur preparation
FR7729531A Granted FR2361398A1 (fr) 1974-03-02 1977-09-30 Nouvelles 6-aryl-4h-s-triazolo-(3,4c)-thieno(2,3e)-1,4-diazepines, leur preparation et leur utilisation en tant que medicaments

Family Applications After (2)

Application Number Title Priority Date Filing Date
FR7601563A Granted FR2287449A1 (fr) 1974-03-02 1976-01-21 Nouvelles 5-aryl-2(subst.)-carbonylhydrazino-3h-(2,3-e)-thieno-1,4-diazepines et procede pour leur preparation
FR7729531A Granted FR2361398A1 (fr) 1974-03-02 1977-09-30 Nouvelles 6-aryl-4h-s-triazolo-(3,4c)-thieno(2,3e)-1,4-diazepines, leur preparation et leur utilisation en tant que medicaments

Country Status (24)

Country Link
US (2) US4094984A (fr)
JP (1) JPS5930713B2 (fr)
AT (1) AT338799B (fr)
BE (1) BE826179A (fr)
BG (3) BG26392A4 (fr)
CA (1) CA1073904A (fr)
CH (1) CH611900A5 (fr)
CS (1) CS203083B2 (fr)
DD (1) DD120022A5 (fr)
DK (1) DK141876C (fr)
ES (2) ES435223A1 (fr)
FI (1) FI59099C (fr)
FR (3) FR2262525B1 (fr)
GB (1) GB1497527A (fr)
IE (1) IE42737B1 (fr)
IL (1) IL52138A0 (fr)
NL (2) NL163515C (fr)
NO (1) NO140671C (fr)
PH (2) PH15360A (fr)
PL (2) PL96223B1 (fr)
RO (3) RO71260B (fr)
SE (1) SE421794B (fr)
SU (2) SU583758A3 (fr)
YU (3) YU39732B (fr)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2378784A1 (fr) * 1977-01-27 1978-08-25 Boehringer Sohn Ingelheim 8-iodo-6-phenyl-4h-s-triazolo (3,4-c) thieno (2,3-e) 1,4-diazepines substituees en position 1, leur preparation et leurs utilisations therapeutiques
EP0000479A1 (fr) * 1977-07-21 1979-02-07 C.H. Boehringer Sohn 1-Pipérazinyl-4H-s-triazolo (3,4-c)thiéno (2,3-e)1,4-diazépines, procédé pour leur préparation et médicaments les contenant
FR2430949A1 (fr) * 1978-07-13 1980-02-08 Boehringer Sohn Ingelheim Nouvelles 4h-s-triazolo (3,4c) thieno (2,3e) 1,4-diazepines, procedes pour leur preparation et medicaments les renfermant

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT338799B (de) * 1974-03-02 1977-09-12 Boehringer Sohn Ingelheim Verfahren zur herstellung neuer substituierter 6-aryl-4h-s-triazolo-(3,4c)-thieno-(2,3e)-1,4-diazepine und ihrer salze
DE2708121A1 (de) * 1977-02-25 1978-09-07 Boehringer Sohn Ingelheim Triazolo-thieno-diazepin-l-one, verfahren zu ihrer herstellung und arzneimittel
PH30676A (en) * 1986-07-22 1997-09-16 Boehringer Ingelhein Kg Hetrazepine compounds which have useful pharmaceutical utility
EP0268242B1 (fr) * 1986-11-17 1992-03-18 Yoshitomi Pharmaceutical Industries, Ltd. Composés du type thiénotriazolodiazépine antagonistes du PAF et leurs applications pharmaceutiques
US4959361A (en) * 1987-12-18 1990-09-25 Hoffmann-La Roche Inc. Triazolo(4,3-A)(1,4)benzodiazepines and thieno (3,2-F)(1,2,4)triazolo(4,3-A)(1,4)diazepine compounds which have useful activity as platelet activating factor (PAF) antagonists
DE4010528A1 (de) * 1990-04-02 1991-10-17 Boehringer Ingelheim Kg Praeparativ chromatographisches trennverfahren zur herstellung enantiomerenreiner hetrazepine
WO1995032963A1 (fr) * 1994-06-01 1995-12-07 Yoshitomi Pharmaceutical Industries, Ltd. Compose de thienylazole et compose de thienotriazolodiazepine
US5552399A (en) * 1994-11-02 1996-09-03 Janssen Pharmaceutica N.V. Substituted tetracyclic azepine derivatives
WO1999063977A2 (fr) 1998-06-09 1999-12-16 Takeda Chemical Industries, Ltd. Composition pharmaceutique destinee a traiter ou prevenir les troubles du sommeil
DE10116378C2 (de) * 2001-04-04 2003-05-28 Boehringer Ingelheim Pharma Verfahren zur Herstellung von 6-Aryl-4H-s-triazolo[3,4-c]-thieno[2,3-e]-1,4-diazepinen
US6884886B2 (en) * 2001-04-04 2005-04-26 Boehringer Ingelheim Pharma Kg Process for preparing 6-aryl-4H-S-triazolo[3,4-c]-thieno[2,3-e]-1,4-diazepines
CN106397452A (zh) * 2016-07-26 2017-02-15 江苏兢业制药有限公司 7‑溴‑5‑(2‑氯苯基)‑1,3‑二氢噻吩并[2,3e]‑1,4‑二氮杂卓‑2‑硫酮的制备方法
JP6843811B2 (ja) 2018-09-19 2021-03-17 岬環境プラン株式会社 撒積貨物船の船艙壁面清掃装置

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3709899A (en) * 1971-04-28 1973-01-09 Upjohn Co 6-phenyl-4h-s-triazolo(4,3-a)(1,4)benzodiazepines and their production
US3751426A (en) * 1971-04-28 1973-08-07 Upjohn Co 1-substituted-6-phenyl-4h-s-triazolo(4,3-a)(1,6)benzodiazepine compounds
US3849934A (en) * 1971-05-03 1974-11-26 Scm Corp Alpha-aryl-n-lower alkyl nitrone-containing compositions useful as anti-fungal agents
US3856802A (en) * 1971-05-10 1974-12-24 Upjohn Co 1,6-DISUBSTITUTED-4H-5-{8 4,3-a{9 BENZODIAZEPINES
GB1323277A (en) * 1971-05-10 1973-07-11 Upjohn Co Triazolobenzodiazepines
US3681343A (en) 1971-05-11 1972-08-01 Upjohn Co 6-phenyl-s-triazolo{8 4,3-a{9 {8 1,4{9 {0 benzodiazepines
US3904641A (en) * 1971-06-18 1975-09-09 Yoshitomi Pharmaceutical Triazolothienodiazepine compounds
GB1332766A (en) * 1971-06-18 1973-10-03 Upjohn Co Triazolo-benzodiazepines
US3767660A (en) * 1971-09-13 1973-10-23 Upjohn Co 4h-s-triazolo(4,3-a)(1,4)benzodiazepines
GB1377230A (en) * 1971-09-13 1974-12-11 Upjohn Co 4h-s-triazolo -4,3-a- 1,4-benzodiazepines
GB1387783A (en) * 1972-08-08 1975-03-19 Yoshitomi Pharmaceutical Thiophene derivatives, method for their preparation and pharmaceutical composition thereof
PH12303A (en) * 1973-02-08 1979-01-16 Hoffmann La Roche Thienotriazolodiazepine derivatives
AT338799B (de) * 1974-03-02 1977-09-12 Boehringer Sohn Ingelheim Verfahren zur herstellung neuer substituierter 6-aryl-4h-s-triazolo-(3,4c)-thieno-(2,3e)-1,4-diazepine und ihrer salze

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2378784A1 (fr) * 1977-01-27 1978-08-25 Boehringer Sohn Ingelheim 8-iodo-6-phenyl-4h-s-triazolo (3,4-c) thieno (2,3-e) 1,4-diazepines substituees en position 1, leur preparation et leurs utilisations therapeutiques
EP0000479A1 (fr) * 1977-07-21 1979-02-07 C.H. Boehringer Sohn 1-Pipérazinyl-4H-s-triazolo (3,4-c)thiéno (2,3-e)1,4-diazépines, procédé pour leur préparation et médicaments les contenant
FR2430949A1 (fr) * 1978-07-13 1980-02-08 Boehringer Sohn Ingelheim Nouvelles 4h-s-triazolo (3,4c) thieno (2,3e) 1,4-diazepines, procedes pour leur preparation et medicaments les renfermant

Also Published As

Publication number Publication date
FR2361398B1 (fr) 1980-09-12
CH611900A5 (fr) 1979-06-29
DK141876C (da) 1980-11-17
IL52138A0 (en) 1977-07-31
NO750691L (fr) 1975-09-03
FI750592A (fr) 1975-09-03
CS203083B2 (en) 1981-02-27
CA1073904A (fr) 1980-03-18
AT338799B (de) 1977-09-12
YU39890B (en) 1985-04-30
SE7502313L (fr) 1975-09-03
YU39891B (en) 1985-04-30
FR2287449A1 (fr) 1976-05-07
US4199588A (en) 1980-04-22
NL163515C (nl) 1980-09-15
US4094984A (en) 1978-06-13
IE42737B1 (en) 1980-10-08
NL163515B (nl) 1980-04-15
DK80775A (fr) 1975-09-03
FR2361398A1 (fr) 1978-03-10
BG26391A4 (bg) 1979-03-15
JPS5180899A (en) 1976-07-15
SU583758A3 (ru) 1977-12-05
RO71260A (fr) 1983-04-29
JPS5930713B2 (ja) 1984-07-28
NL7502391A (nl) 1975-09-04
YU102482A (en) 1982-08-31
FR2287449B1 (fr) 1979-06-22
BG26392A4 (bg) 1979-03-15
RO71261B (ro) 1983-04-30
ATA108975A (de) 1977-01-15
PL96223B1 (pl) 1977-12-31
YU102582A (en) 1982-08-31
GB1497527A (en) 1978-01-12
BE826179A (fr) 1975-08-28
PH15360A (en) 1982-12-10
FI59099B (fi) 1981-02-27
RO71260B (ro) 1983-04-30
DK141876B (da) 1980-07-07
IE42737L (en) 1975-09-02
YU39732B (en) 1985-04-30
SE421794B (sv) 1982-02-01
SU648104A3 (ru) 1979-02-15
ES435223A1 (es) 1977-05-01
NO140671B (no) 1979-07-09
ES437261A1 (es) 1977-04-01
FR2262525B1 (fr) 1978-08-18
RO66909A (fr) 1981-03-21
FI59099C (fi) 1981-06-10
PL99177B1 (pl) 1978-06-30
PH15120A (en) 1982-08-10
YU47775A (en) 1982-08-31
NL930123I1 (nl) 1993-11-01
BG26390A3 (bg) 1979-03-15
NO140671C (no) 1979-10-17
RO71261A (fr) 1983-04-29
DD120022A5 (fr) 1976-05-20

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Legal Events

Date Code Title Description
CC Supplementary protection certificate (spc) laid open to the public (law of 25 june 1990)

Free format text: 92C0234, 920521

CC Supplementary protection certificate (spc) laid open to the public (law of 25 june 1990)

Free format text: 92C0237, 920521

CB Supplementary protection certificate (spc) granted (law of 25 june 1990)

Free format text: 92C0234, 750228

CB Supplementary protection certificate (spc) granted (law of 25 june 1990)

Free format text: 92C0237, 750228

CL Concession to grant licences