FR12C0053I2 - Dihydropyridines a activite courte - Google Patents
Dihydropyridines a activite courteInfo
- Publication number
- FR12C0053I2 FR12C0053I2 FR12C0053C FR12C0053C FR12C0053I2 FR 12C0053 I2 FR12C0053 I2 FR 12C0053I2 FR 12C0053 C FR12C0053 C FR 12C0053C FR 12C0053 C FR12C0053 C FR 12C0053C FR 12C0053 I2 FR12C0053 I2 FR 12C0053I2
- Authority
- FR
- France
- Prior art keywords
- dihydropyridines
- short activity
- activity
- short
- activity dihydropyridines
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
- C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE9303657A SE9303657D0 (sv) | 1993-11-05 | 1993-11-05 | Short-acting dihydropyridines |
| PCT/SE1994/001031 WO1995012578A1 (en) | 1993-11-05 | 1994-11-03 | Short-acting dihydropyridines |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FR12C0053I1 FR12C0053I1 (cs) | 2012-02-11 |
| FR12C0053I2 true FR12C0053I2 (fr) | 2013-08-16 |
Family
ID=20391655
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR12C0053C Active FR12C0053I2 (fr) | 1993-11-05 | 2012-09-18 | Dihydropyridines a activite courte |
Country Status (35)
| Country | Link |
|---|---|
| US (1) | US5856346A (cs) |
| EP (1) | EP0726894B1 (cs) |
| JP (1) | JP3712209B2 (cs) |
| KR (1) | KR100331663B1 (cs) |
| CN (1) | CN1049428C (cs) |
| AT (1) | ATE194330T1 (cs) |
| AU (1) | AU685532B2 (cs) |
| BR (1) | BR9407946A (cs) |
| CA (1) | CA2174969C (cs) |
| CZ (1) | CZ285691B6 (cs) |
| DE (1) | DE69425152T2 (cs) |
| DK (1) | DK0726894T3 (cs) |
| EE (1) | EE03230B1 (cs) |
| EG (1) | EG20539A (cs) |
| ES (1) | ES2150544T3 (cs) |
| FI (1) | FI110429B (cs) |
| FR (1) | FR12C0053I2 (cs) |
| GR (1) | GR3034469T3 (cs) |
| HU (1) | HU215591B (cs) |
| IL (1) | IL111127A (cs) |
| IS (1) | IS1674B (cs) |
| LU (1) | LU92209I2 (cs) |
| MY (1) | MY111770A (cs) |
| NO (1) | NO305656B1 (cs) |
| NZ (1) | NZ275915A (cs) |
| PL (1) | PL185099B1 (cs) |
| PT (1) | PT726894E (cs) |
| RU (1) | RU2139278C1 (cs) |
| SA (1) | SA94150250B1 (cs) |
| SE (1) | SE9303657D0 (cs) |
| SK (1) | SK281467B6 (cs) |
| TW (1) | TW279859B (cs) |
| UA (1) | UA45959C2 (cs) |
| WO (1) | WO1995012578A1 (cs) |
| ZA (1) | ZA947570B (cs) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE9804002D0 (sv) * | 1998-11-23 | 1998-11-23 | Astra Ab | New manufacturing process |
| BR0215176A (pt) * | 2001-12-21 | 2004-11-30 | Alcon Inc | Uso de nanopartìculas como veìculos para biocidas em composições oftálmicas |
| FR2922439B1 (fr) * | 2007-10-18 | 2010-12-10 | Hill Rom Ind Sa | Procede de gonflage alterne d'un dispositif de support a cellules gonflables et dispositif pour sa mise en oeuvre |
| US20100113534A1 (en) | 2008-08-01 | 2010-05-06 | Rajeshwar Motheram | Pharmaceutical Compositions And Methods For Producing Low Impurity Concentrations Of The Same |
| ES2543470T3 (es) * | 2009-09-30 | 2015-08-19 | Microdose Therapeutx, Inc. | Métodos y composiciones para el tratamiento del fenómeno de Raynaud |
| CN101780036B (zh) * | 2010-03-30 | 2011-11-16 | 武汉武药科技有限公司 | 丁酸氯维地平脂微球注射液及其制备方法 |
| CA2701087A1 (en) * | 2010-04-12 | 2011-10-12 | Alphora Research Inc. | Preparation of clevidipine butyrate ring the same |
| US8455655B2 (en) | 2010-05-07 | 2013-06-04 | Laboratorios Lesvi, S.L. | Preparation of dihydropyridines |
| ES2571043T3 (es) | 2010-05-07 | 2016-05-23 | Lesvi Laboratorios Sl | Preparación de dihidropiridinas |
| NZ610465A (en) | 2010-10-12 | 2015-05-29 | Medicines Co | Clevidipine emulsion formulations containing antimicrobial agents |
| US8658676B2 (en) | 2010-10-12 | 2014-02-25 | The Medicines Company | Clevidipine emulsion formulations containing antimicrobial agents |
| CA2832066C (en) | 2011-04-01 | 2023-04-18 | The Medicines Company | Short-acting dihydropyridines (clevidipine) for use in reducing stroke damage |
| EP2747757A1 (en) | 2011-08-26 | 2014-07-02 | Wockhardt Limited | Methods for treating cardiovascular disorders |
| CN103420899B (zh) * | 2012-05-25 | 2016-01-27 | 四川科伦药物研究有限公司 | 一种丁酸氯维地平的纯化方法 |
| ES2671639T3 (es) | 2012-10-26 | 2018-06-07 | Chiesi Farmaceutici S.P.A. | Métodos para controlar la presión arterial y reducir la disnea en la insuficiencia cardiaca |
| CN103073485B (zh) * | 2013-01-17 | 2015-09-02 | 北京嘉林药业股份有限公司 | 一种丁酸氯维地平的制备方法 |
| CN103086956B (zh) * | 2013-01-17 | 2015-11-04 | 北京嘉林药业股份有限公司 | 一种丁酸氯维地平中间体的纯化方法 |
| RU2759673C2 (ru) | 2014-05-19 | 2021-11-16 | КЬЕЗИ ФАРМАЧЕУТИЧИ С.п.А. | Наночастицы клевидипина и их фармацевтические композиции |
| CN105367487A (zh) * | 2014-08-23 | 2016-03-02 | 南京海纳医药科技有限公司 | 一种丁酸氯维地平重要中间体新的合成方法 |
| CN104370802A (zh) * | 2014-09-24 | 2015-02-25 | 北京蓝丹医药科技有限公司 | 氯维地平衍生物及其制备方法 |
| BR112017024773A2 (pt) | 2015-05-20 | 2018-11-06 | Merial, Inc. | compostos depsipeptídeos anti-helmínticos |
| US10344056B2 (en) | 2015-12-28 | 2019-07-09 | Boehringer Ingelheim Animal Health USA Inc. | Anthelmintic depsipeptide compounds |
| US11382949B2 (en) | 2016-11-16 | 2022-07-12 | Boehringer Ingelheim Animal Health USA Inc. | Anthelmintic depsipeptide compounds |
| RU2755349C1 (ru) * | 2021-02-16 | 2021-09-15 | Федеральное государственное автономное образовательное учреждение высшего образования "Белгородский государственный национальный исследовательский университет" (НИУ "БелГУ") | Применение бензил 6-({ 2-[(3,4-диметилфенил)амино]-2-оксоэтил} тио)-2-метил-4-(4-хлорфенил)-5-циано-1,4-дигидропиридин-3-карбоксилата в качестве гепатопротекторного средства |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2117571C3 (de) * | 1971-04-10 | 1979-10-11 | Bayer Ag, 5090 Leverkusen | Unsymmetrische 1,4-Dihydropyridin-33-dicarbonsäureester, Verfahren zu ihrer Herstellung sowie ihre Verwendung als Arzneimittel |
| US4154839A (en) * | 1975-11-05 | 1979-05-15 | Bayer Aktiengesellschaft | 2,6-Dimethyl-3-carboxymethoxy-4-(2-nitrophenyl)-5-carbisobutoxy-1,4-dihydropyridine |
| DE2847236A1 (de) * | 1978-10-31 | 1980-05-14 | Bayer Ag | Neue dihydropyridine mit substituierten estergruppierungen, mehrer verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel |
| KR940003492B1 (ko) * | 1988-10-27 | 1994-04-23 | 주식회사 유한양행 | 1,4-디하이드로피리딘유도체 및 그의 제조방법 |
| US5134139A (en) * | 1989-08-31 | 1992-07-28 | Tanabe Seiyaku Co., Ltd. | 1,5-benzothiazepine derivatives and preparation thereof |
| JPH0641075A (ja) * | 1990-09-01 | 1994-02-15 | Kazuo Achinami | 新規な１，４−ジヒドロピリジン化合物及びその製造方法 |
-
1993
- 1993-11-05 SE SE9303657A patent/SE9303657D0/xx unknown
-
1994
- 1994-09-28 ZA ZA947570A patent/ZA947570B/xx unknown
- 1994-09-29 TW TW083108995A patent/TW279859B/zh not_active IP Right Cessation
- 1994-09-30 IS IS4218A patent/IS1674B/is unknown
- 1994-10-03 IL IL11112794A patent/IL111127A/xx not_active IP Right Cessation
- 1994-10-19 SA SA94150250A patent/SA94150250B1/ar unknown
- 1994-11-02 EG EG68994A patent/EG20539A/xx active
- 1994-11-03 CZ CZ961273A patent/CZ285691B6/cs not_active IP Right Cessation
- 1994-11-03 EE EE9600051A patent/EE03230B1/xx unknown
- 1994-11-03 DK DK95900347T patent/DK0726894T3/da active
- 1994-11-03 JP JP51317095A patent/JP3712209B2/ja not_active Expired - Lifetime
- 1994-11-03 BR BR9407946A patent/BR9407946A/pt not_active Application Discontinuation
- 1994-11-03 US US08/356,224 patent/US5856346A/en not_active Expired - Lifetime
- 1994-11-03 SK SK559-96A patent/SK281467B6/sk not_active IP Right Cessation
- 1994-11-03 WO PCT/SE1994/001031 patent/WO1995012578A1/en not_active Ceased
- 1994-11-03 UA UA96041753A patent/UA45959C2/uk unknown
- 1994-11-03 ES ES95900347T patent/ES2150544T3/es not_active Expired - Lifetime
- 1994-11-03 EP EP95900347A patent/EP0726894B1/en not_active Expired - Lifetime
- 1994-11-03 PL PL94314128A patent/PL185099B1/pl unknown
- 1994-11-03 DE DE69425152T patent/DE69425152T2/de not_active Expired - Lifetime
- 1994-11-03 AT AT95900347T patent/ATE194330T1/de active
- 1994-11-03 KR KR1019960702346A patent/KR100331663B1/ko not_active Expired - Lifetime
- 1994-11-03 NZ NZ275915A patent/NZ275915A/en not_active IP Right Cessation
- 1994-11-03 CA CA002174969A patent/CA2174969C/en not_active Expired - Lifetime
- 1994-11-03 HU HU9601187A patent/HU215591B/hu unknown
- 1994-11-03 RU RU96112152A patent/RU2139278C1/ru active
- 1994-11-03 AU AU81196/94A patent/AU685532B2/en not_active Expired
- 1994-11-03 CN CN94194500A patent/CN1049428C/zh not_active Expired - Lifetime
- 1994-11-03 PT PT95900347T patent/PT726894E/pt unknown
- 1994-11-04 MY MYPI94002934A patent/MY111770A/en unknown
-
1996
- 1996-05-02 NO NO961776A patent/NO305656B1/no not_active IP Right Cessation
- 1996-05-06 FI FI961914A patent/FI110429B/fi not_active IP Right Cessation
-
2000
- 2000-09-21 GR GR20000402158T patent/GR3034469T3/el unknown
-
2012
- 2012-09-18 FR FR12C0053C patent/FR12C0053I2/fr active Active
-
2013
- 2013-06-10 LU LU92209C patent/LU92209I2/fr unknown
Also Published As
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