ATE194330T1 - Dihydropyridine mit kurzer wirkung - Google Patents
Dihydropyridine mit kurzer wirkungInfo
- Publication number
- ATE194330T1 ATE194330T1 AT95900347T AT95900347T ATE194330T1 AT E194330 T1 ATE194330 T1 AT E194330T1 AT 95900347 T AT95900347 T AT 95900347T AT 95900347 T AT95900347 T AT 95900347T AT E194330 T1 ATE194330 T1 AT E194330T1
- Authority
- AT
- Austria
- Prior art keywords
- hydrogen
- pct
- chloro
- methyl
- nitro
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
- C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Cardiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE9303657A SE9303657D0 (sv) | 1993-11-05 | 1993-11-05 | Short-acting dihydropyridines |
PCT/SE1994/001031 WO1995012578A1 (en) | 1993-11-05 | 1994-11-03 | Short-acting dihydropyridines |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE194330T1 true ATE194330T1 (de) | 2000-07-15 |
Family
ID=20391655
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT95900347T ATE194330T1 (de) | 1993-11-05 | 1994-11-03 | Dihydropyridine mit kurzer wirkung |
Country Status (36)
Country | Link |
---|---|
US (1) | US5856346A (de) |
EP (1) | EP0726894B1 (de) |
JP (1) | JP3712209B2 (de) |
KR (1) | KR100331663B1 (de) |
CN (1) | CN1049428C (de) |
AT (1) | ATE194330T1 (de) |
AU (1) | AU685532B2 (de) |
BR (1) | BR9407946A (de) |
CA (1) | CA2174969C (de) |
CZ (1) | CZ285691B6 (de) |
DE (1) | DE69425152T2 (de) |
DK (1) | DK0726894T3 (de) |
EE (1) | EE03230B1 (de) |
EG (1) | EG20539A (de) |
ES (1) | ES2150544T3 (de) |
FI (1) | FI110429B (de) |
FR (1) | FR12C0053I2 (de) |
GR (1) | GR3034469T3 (de) |
HK (1) | HK1013292A1 (de) |
HU (1) | HU215591B (de) |
IL (1) | IL111127A (de) |
IS (1) | IS1674B (de) |
LU (1) | LU92209I2 (de) |
MY (1) | MY111770A (de) |
NO (1) | NO305656B1 (de) |
NZ (1) | NZ275915A (de) |
PL (1) | PL185099B1 (de) |
PT (1) | PT726894E (de) |
RU (1) | RU2139278C1 (de) |
SA (1) | SA94150250B1 (de) |
SE (1) | SE9303657D0 (de) |
SK (1) | SK281467B6 (de) |
TW (1) | TW279859B (de) |
UA (1) | UA45959C2 (de) |
WO (1) | WO1995012578A1 (de) |
ZA (1) | ZA947570B (de) |
Families Citing this family (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SE9804002D0 (sv) * | 1998-11-23 | 1998-11-23 | Astra Ab | New manufacturing process |
WO2003059193A2 (en) * | 2001-12-21 | 2003-07-24 | Alcon, Inc. | Use of nanoparticles as carriers for biocides in ophthalmic compositions |
FR2922439B1 (fr) * | 2007-10-18 | 2010-12-10 | Hill Rom Ind Sa | Procede de gonflage alterne d'un dispositif de support a cellules gonflables et dispositif pour sa mise en oeuvre |
SI2320740T1 (sl) | 2008-08-01 | 2014-08-29 | The Medicines Company | Farmacevtski sestavki clevidipina in postopki za izdelavo nizke koncentracije neäśistoäś le-teh |
PL2482658T3 (pl) * | 2009-09-30 | 2015-10-30 | Microdose Therapeutx Inc | Sposoby i kompozycje do leczenia objawu Raynauda |
CN101780036B (zh) * | 2010-03-30 | 2011-11-16 | 武汉武药科技有限公司 | 丁酸氯维地平脂微球注射液及其制备方法 |
CA2701087A1 (en) * | 2010-04-12 | 2011-10-12 | Alphora Research Inc. | Preparation of clevidipine butyrate ring the same |
EP3020704A3 (de) | 2010-05-07 | 2016-11-09 | Laboratorios Lesvi, S.L. | Kristalline polymorphen des clevidipins butyrate |
US8455655B2 (en) | 2010-05-07 | 2013-06-04 | Laboratorios Lesvi, S.L. | Preparation of dihydropyridines |
EA022849B1 (ru) | 2010-10-12 | 2016-03-31 | Дзе Медсинз Компани | Эмульсионные композиции клевидипина, содержащие противомикробные агенты |
US8658676B2 (en) | 2010-10-12 | 2014-02-25 | The Medicines Company | Clevidipine emulsion formulations containing antimicrobial agents |
BR112013025368A8 (pt) * | 2011-04-01 | 2018-06-12 | The Medicines Co | Medicamento, método para preparar um medicamento útil para reduzir danos por derrame em um sujeito com derrame, método para preparar um medicamento útil para reduzir a pressão sanguínea e reduzir danos por derrame em um sujeito com derrame |
AU2012303683B2 (en) | 2011-08-26 | 2016-09-08 | Wockhardt Limited | Methods for treating cardiovascular disorders |
CN103420899B (zh) * | 2012-05-25 | 2016-01-27 | 四川科伦药物研究有限公司 | 一种丁酸氯维地平的纯化方法 |
AU2013334081B2 (en) | 2012-10-26 | 2017-05-18 | Chiesi Farmaceutici S.P.A. | Methods for controlling blood pressure and reducing dyspnea in heart failure |
CN103073485B (zh) * | 2013-01-17 | 2015-09-02 | 北京嘉林药业股份有限公司 | 一种丁酸氯维地平的制备方法 |
CN103086956B (zh) * | 2013-01-17 | 2015-11-04 | 北京嘉林药业股份有限公司 | 一种丁酸氯维地平中间体的纯化方法 |
RU2759673C2 (ru) | 2014-05-19 | 2021-11-16 | КЬЕЗИ ФАРМАЧЕУТИЧИ С.п.А. | Наночастицы клевидипина и их фармацевтические композиции |
CN105367487A (zh) * | 2014-08-23 | 2016-03-02 | 南京海纳医药科技有限公司 | 一种丁酸氯维地平重要中间体新的合成方法 |
CN104370802A (zh) * | 2014-09-24 | 2015-02-25 | 北京蓝丹医药科技有限公司 | 氯维地平衍生物及其制备方法 |
RS62130B1 (sr) | 2015-05-20 | 2021-08-31 | Boehringer Ingelheim Animal Health Usa Inc | Antihelmintička depsipeptidna jedinjenja |
RU2715556C2 (ru) | 2015-12-28 | 2020-03-02 | Мериал, Инк. | Противогельминтные депсипептидные соединения |
WO2018093920A1 (en) | 2016-11-16 | 2018-05-24 | Merial, Inc. | Anthelmintic depsipeptide compounds |
RU2755349C1 (ru) * | 2021-02-16 | 2021-09-15 | Федеральное государственное автономное образовательное учреждение высшего образования "Белгородский государственный национальный исследовательский университет" (НИУ "БелГУ") | Применение бензил 6-({ 2-[(3,4-диметилфенил)амино]-2-оксоэтил} тио)-2-метил-4-(4-хлорфенил)-5-циано-1,4-дигидропиридин-3-карбоксилата в качестве гепатопротекторного средства |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2117571C3 (de) * | 1971-04-10 | 1979-10-11 | Bayer Ag, 5090 Leverkusen | Unsymmetrische 1,4-Dihydropyridin-33-dicarbonsäureester, Verfahren zu ihrer Herstellung sowie ihre Verwendung als Arzneimittel |
US4154839A (en) * | 1975-11-05 | 1979-05-15 | Bayer Aktiengesellschaft | 2,6-Dimethyl-3-carboxymethoxy-4-(2-nitrophenyl)-5-carbisobutoxy-1,4-dihydropyridine |
DE2847236A1 (de) * | 1978-10-31 | 1980-05-14 | Bayer Ag | Neue dihydropyridine mit substituierten estergruppierungen, mehrer verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel |
KR940003492B1 (ko) * | 1988-10-27 | 1994-04-23 | 주식회사 유한양행 | 1,4-디하이드로피리딘유도체 및 그의 제조방법 |
US5134139A (en) * | 1989-08-31 | 1992-07-28 | Tanabe Seiyaku Co., Ltd. | 1,5-benzothiazepine derivatives and preparation thereof |
JPH0641075A (ja) * | 1990-09-01 | 1994-02-15 | Kazuo Achinami | 新規な1,4−ジヒドロピリジン化合物及びその製造方法 |
-
1993
- 1993-11-05 SE SE9303657A patent/SE9303657D0/xx unknown
-
1994
- 1994-09-28 ZA ZA947570A patent/ZA947570B/xx unknown
- 1994-09-29 TW TW083108995A patent/TW279859B/zh not_active IP Right Cessation
- 1994-09-30 IS IS4218A patent/IS1674B/is unknown
- 1994-10-03 IL IL11112794A patent/IL111127A/xx not_active IP Right Cessation
- 1994-10-19 SA SA94150250A patent/SA94150250B1/ar unknown
- 1994-11-02 EG EG68994A patent/EG20539A/xx active
- 1994-11-03 CA CA002174969A patent/CA2174969C/en not_active Expired - Lifetime
- 1994-11-03 US US08/356,224 patent/US5856346A/en not_active Expired - Lifetime
- 1994-11-03 PT PT95900347T patent/PT726894E/pt unknown
- 1994-11-03 EE EE9600051A patent/EE03230B1/xx unknown
- 1994-11-03 AU AU81196/94A patent/AU685532B2/en not_active Expired
- 1994-11-03 NZ NZ275915A patent/NZ275915A/en not_active IP Right Cessation
- 1994-11-03 DE DE69425152T patent/DE69425152T2/de not_active Expired - Lifetime
- 1994-11-03 DK DK95900347T patent/DK0726894T3/da active
- 1994-11-03 BR BR9407946A patent/BR9407946A/pt not_active Application Discontinuation
- 1994-11-03 HU HU9601187A patent/HU215591B/hu unknown
- 1994-11-03 ES ES95900347T patent/ES2150544T3/es not_active Expired - Lifetime
- 1994-11-03 SK SK559-96A patent/SK281467B6/sk not_active IP Right Cessation
- 1994-11-03 EP EP95900347A patent/EP0726894B1/de not_active Expired - Lifetime
- 1994-11-03 CZ CZ961273A patent/CZ285691B6/cs not_active IP Right Cessation
- 1994-11-03 AT AT95900347T patent/ATE194330T1/de active
- 1994-11-03 KR KR1019960702346A patent/KR100331663B1/ko not_active IP Right Cessation
- 1994-11-03 JP JP51317095A patent/JP3712209B2/ja not_active Expired - Lifetime
- 1994-11-03 PL PL94314128A patent/PL185099B1/pl unknown
- 1994-11-03 UA UA96041753A patent/UA45959C2/uk unknown
- 1994-11-03 WO PCT/SE1994/001031 patent/WO1995012578A1/en active IP Right Grant
- 1994-11-03 RU RU96112152A patent/RU2139278C1/ru active
- 1994-11-03 CN CN94194500A patent/CN1049428C/zh not_active Expired - Lifetime
- 1994-11-04 MY MYPI94002934A patent/MY111770A/en unknown
-
1996
- 1996-05-02 NO NO961776A patent/NO305656B1/no not_active IP Right Cessation
- 1996-05-06 FI FI961914A patent/FI110429B/fi not_active IP Right Cessation
-
1998
- 1998-12-22 HK HK98114638A patent/HK1013292A1/xx unknown
-
2000
- 2000-09-21 GR GR20000402158T patent/GR3034469T3/el unknown
-
2012
- 2012-09-18 FR FR12C0053C patent/FR12C0053I2/fr active Active
-
2013
- 2013-06-10 LU LU92209C patent/LU92209I2/fr unknown
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ATE194330T1 (de) | Dihydropyridine mit kurzer wirkung | |
DE69221721D1 (de) | Ethanolaminderivate mit anti-pollakiurawirkung | |
ATE88468T1 (de) | Arylalkoxycumarine, verfahren zu ihrer herstellung und diese enthaltende therapeutische mittel. | |
IL108970A0 (en) | Substituted (arylalkylaminobenzyl) aminopropionamide derivatives, their preparation and pharmaceutical compositions containing them | |
DK0689534T3 (da) | Amidderivater som 5-HT1A-ligander | |
NO973242L (no) | Anvendelse av 3,4-difenylkromaner til fremstilling av et farmasöytisk preparat for behandling eller profylakse av idiopatisk eller fysiologisk gynekomasti | |
ES2006165A6 (es) | Procedimiento para la preparacion de derivados de 1,4-dihidropiridina y sus sales de adicion farmaceuticamente aceptables |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
UEP | Publication of translation of european patent specification |