FR12C0053I2 - Dihydropyridines a activite courte - Google Patents
Dihydropyridines a activite courteInfo
- Publication number
- FR12C0053I2 FR12C0053I2 FR12C0053C FR12C0053C FR12C0053I2 FR 12C0053 I2 FR12C0053 I2 FR 12C0053I2 FR 12C0053 C FR12C0053 C FR 12C0053C FR 12C0053 C FR12C0053 C FR 12C0053C FR 12C0053 I2 FR12C0053 I2 FR 12C0053I2
- Authority
- FR
- France
- Prior art keywords
- dihydropyridines
- short activity
- activity
- short
- activity dihydropyridines
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
- C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE9303657A SE9303657D0 (sv) | 1993-11-05 | 1993-11-05 | Short-acting dihydropyridines |
| PCT/SE1994/001031 WO1995012578A1 (fr) | 1993-11-05 | 1994-11-03 | Dihydropyridines a activite courte |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FR12C0053I1 FR12C0053I1 (fr) | 2012-02-11 |
| FR12C0053I2 true FR12C0053I2 (fr) | 2013-08-16 |
Family
ID=20391655
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR12C0053C Active FR12C0053I2 (fr) | 1993-11-05 | 2012-09-18 | Dihydropyridines a activite courte |
Country Status (36)
| Country | Link |
|---|---|
| US (1) | US5856346A (fr) |
| EP (1) | EP0726894B1 (fr) |
| JP (1) | JP3712209B2 (fr) |
| KR (1) | KR100331663B1 (fr) |
| CN (1) | CN1049428C (fr) |
| AT (1) | ATE194330T1 (fr) |
| AU (1) | AU685532B2 (fr) |
| BR (1) | BR9407946A (fr) |
| CA (1) | CA2174969C (fr) |
| CZ (1) | CZ285691B6 (fr) |
| DE (1) | DE69425152T2 (fr) |
| DK (1) | DK0726894T3 (fr) |
| EE (1) | EE03230B1 (fr) |
| EG (1) | EG20539A (fr) |
| ES (1) | ES2150544T3 (fr) |
| FI (1) | FI110429B (fr) |
| FR (1) | FR12C0053I2 (fr) |
| GR (1) | GR3034469T3 (fr) |
| HK (1) | HK1013292A1 (fr) |
| HU (1) | HU215591B (fr) |
| IL (1) | IL111127A (fr) |
| IS (1) | IS1674B (fr) |
| LU (1) | LU92209I2 (fr) |
| MY (1) | MY111770A (fr) |
| NO (1) | NO305656B1 (fr) |
| NZ (1) | NZ275915A (fr) |
| PL (1) | PL185099B1 (fr) |
| PT (1) | PT726894E (fr) |
| RU (1) | RU2139278C1 (fr) |
| SA (1) | SA94150250B1 (fr) |
| SE (1) | SE9303657D0 (fr) |
| SK (1) | SK281467B6 (fr) |
| TW (1) | TW279859B (fr) |
| UA (1) | UA45959C2 (fr) |
| WO (1) | WO1995012578A1 (fr) |
| ZA (1) | ZA947570B (fr) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE9804002D0 (sv) * | 1998-11-23 | 1998-11-23 | Astra Ab | New manufacturing process |
| WO2003059193A2 (fr) * | 2001-12-21 | 2003-07-24 | Alcon, Inc. | Utilisation de nanoparticules en tant qu'excipients pour biocides dans des compositions ophtalmiques |
| FR2922439B1 (fr) * | 2007-10-18 | 2010-12-10 | Hill Rom Ind Sa | Procede de gonflage alterne d'un dispositif de support a cellules gonflables et dispositif pour sa mise en oeuvre |
| NZ591205A (en) | 2008-08-01 | 2012-11-30 | Medicines Co | Pharmaceutical compositions comprising clevidipine and methods for producing low impurity concentrations of the same |
| KR20120100945A (ko) * | 2009-09-30 | 2012-09-12 | 마이크로도스 테라퓨특스, 인코포레이티드 | 레이노 증후군의 치료를 위한 방법들 및 조성물들 |
| CN101780036B (zh) * | 2010-03-30 | 2011-11-16 | 武汉武药科技有限公司 | 丁酸氯维地平脂微球注射液及其制备方法 |
| CA2701087A1 (fr) * | 2010-04-12 | 2011-10-12 | Alphora Research Inc. | Preparation de butyrate de clevidipine |
| US8455655B2 (en) | 2010-05-07 | 2013-06-04 | Laboratorios Lesvi, S.L. | Preparation of dihydropyridines |
| EP2386544B1 (fr) | 2010-05-07 | 2016-02-10 | Laboratorios Lesvi, S.L. | Préparation of dihydropyridines |
| US8658676B2 (en) | 2010-10-12 | 2014-02-25 | The Medicines Company | Clevidipine emulsion formulations containing antimicrobial agents |
| NZ610465A (en) | 2010-10-12 | 2015-05-29 | Medicines Co | Clevidipine emulsion formulations containing antimicrobial agents |
| EP2694063A1 (fr) * | 2011-04-01 | 2014-02-12 | The Medicines Company | Utilisation des dihydropyridines (clévidipine) à courte durée d'action pour réduire des lésions consécutives à un accident vasculaire cérébral |
| EP2747757A1 (fr) | 2011-08-26 | 2014-07-02 | Wockhardt Limited | Procédés de traitement de troubles cardiovasculaires |
| CN103420899B (zh) * | 2012-05-25 | 2016-01-27 | 四川科伦药物研究有限公司 | 一种丁酸氯维地平的纯化方法 |
| CN104968199A (zh) | 2012-10-26 | 2015-10-07 | 医药公司 | 用于在心力衰竭中控制血压和减轻呼吸困难的方法 |
| CN103073485B (zh) * | 2013-01-17 | 2015-09-02 | 北京嘉林药业股份有限公司 | 一种丁酸氯维地平的制备方法 |
| CN103086956B (zh) * | 2013-01-17 | 2015-11-04 | 北京嘉林药业股份有限公司 | 一种丁酸氯维地平中间体的纯化方法 |
| WO2015179334A1 (fr) | 2014-05-19 | 2015-11-26 | The Medicines Company | Nanoparticules de clévidipine et compositions pharmaceutiques les contenant |
| CN105367487A (zh) * | 2014-08-23 | 2016-03-02 | 南京海纳医药科技有限公司 | 一种丁酸氯维地平重要中间体新的合成方法 |
| CN104370802A (zh) * | 2014-09-24 | 2015-02-25 | 北京蓝丹医药科技有限公司 | 氯维地平衍生物及其制备方法 |
| PL3298027T3 (pl) | 2015-05-20 | 2021-11-08 | Boehringer Ingelheim Animal Health USA Inc. | Przeciwrobacze związki depsipeptydów |
| AU2016380868B2 (en) | 2015-12-28 | 2019-11-28 | Boehringer Ingelheim Animal Health USA Inc. | Anthelmintic depsipeptide compounds |
| US11382949B2 (en) | 2016-11-16 | 2022-07-12 | Boehringer Ingelheim Animal Health USA Inc. | Anthelmintic depsipeptide compounds |
| RU2755349C1 (ru) * | 2021-02-16 | 2021-09-15 | Федеральное государственное автономное образовательное учреждение высшего образования "Белгородский государственный национальный исследовательский университет" (НИУ "БелГУ") | Применение бензил 6-({ 2-[(3,4-диметилфенил)амино]-2-оксоэтил} тио)-2-метил-4-(4-хлорфенил)-5-циано-1,4-дигидропиридин-3-карбоксилата в качестве гепатопротекторного средства |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2117571C3 (de) * | 1971-04-10 | 1979-10-11 | Bayer Ag, 5090 Leverkusen | Unsymmetrische 1,4-Dihydropyridin-33-dicarbonsäureester, Verfahren zu ihrer Herstellung sowie ihre Verwendung als Arzneimittel |
| US4154839A (en) * | 1975-11-05 | 1979-05-15 | Bayer Aktiengesellschaft | 2,6-Dimethyl-3-carboxymethoxy-4-(2-nitrophenyl)-5-carbisobutoxy-1,4-dihydropyridine |
| DE2847236A1 (de) * | 1978-10-31 | 1980-05-14 | Bayer Ag | Neue dihydropyridine mit substituierten estergruppierungen, mehrer verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel |
| KR940003492B1 (ko) * | 1988-10-27 | 1994-04-23 | 주식회사 유한양행 | 1,4-디하이드로피리딘유도체 및 그의 제조방법 |
| US5134139A (en) * | 1989-08-31 | 1992-07-28 | Tanabe Seiyaku Co., Ltd. | 1,5-benzothiazepine derivatives and preparation thereof |
| JPH0641075A (ja) * | 1990-09-01 | 1994-02-15 | Kazuo Achinami | 新規な１，４−ジヒドロピリジン化合物及びその製造方法 |
-
1993
- 1993-11-05 SE SE9303657A patent/SE9303657D0/xx unknown
-
1994
- 1994-09-28 ZA ZA947570A patent/ZA947570B/xx unknown
- 1994-09-29 TW TW083108995A patent/TW279859B/zh not_active IP Right Cessation
- 1994-09-30 IS IS4218A patent/IS1674B/is unknown
- 1994-10-03 IL IL11112794A patent/IL111127A/xx not_active IP Right Cessation
- 1994-10-19 SA SA94150250A patent/SA94150250B1/ar unknown
- 1994-11-02 EG EG68994A patent/EG20539A/xx active
- 1994-11-03 PT PT95900347T patent/PT726894E/pt unknown
- 1994-11-03 HU HU9601187A patent/HU215591B/hu unknown
- 1994-11-03 KR KR1019960702346A patent/KR100331663B1/ko not_active IP Right Cessation
- 1994-11-03 AT AT95900347T patent/ATE194330T1/de active
- 1994-11-03 DK DK95900347T patent/DK0726894T3/da active
- 1994-11-03 WO PCT/SE1994/001031 patent/WO1995012578A1/fr active IP Right Grant
- 1994-11-03 CZ CZ961273A patent/CZ285691B6/cs not_active IP Right Cessation
- 1994-11-03 NZ NZ275915A patent/NZ275915A/en not_active IP Right Cessation
- 1994-11-03 AU AU81196/94A patent/AU685532B2/en not_active Expired
- 1994-11-03 BR BR9407946A patent/BR9407946A/pt not_active Application Discontinuation
- 1994-11-03 RU RU96112152A patent/RU2139278C1/ru active
- 1994-11-03 SK SK559-96A patent/SK281467B6/sk not_active IP Right Cessation
- 1994-11-03 US US08/356,224 patent/US5856346A/en not_active Expired - Lifetime
- 1994-11-03 CA CA002174969A patent/CA2174969C/fr not_active Expired - Lifetime
- 1994-11-03 UA UA96041753A patent/UA45959C2/uk unknown
- 1994-11-03 DE DE69425152T patent/DE69425152T2/de not_active Expired - Lifetime
- 1994-11-03 EE EE9600051A patent/EE03230B1/xx unknown
- 1994-11-03 CN CN94194500A patent/CN1049428C/zh not_active Expired - Lifetime
- 1994-11-03 PL PL94314128A patent/PL185099B1/pl unknown
- 1994-11-03 JP JP51317095A patent/JP3712209B2/ja not_active Expired - Lifetime
- 1994-11-03 EP EP95900347A patent/EP0726894B1/fr not_active Expired - Lifetime
- 1994-11-03 ES ES95900347T patent/ES2150544T3/es not_active Expired - Lifetime
- 1994-11-04 MY MYPI94002934A patent/MY111770A/en unknown
-
1996
- 1996-05-02 NO NO961776A patent/NO305656B1/no not_active IP Right Cessation
- 1996-05-06 FI FI961914A patent/FI110429B/fi not_active IP Right Cessation
-
1998
- 1998-12-22 HK HK98114638A patent/HK1013292A1/xx unknown
-
2000
- 2000-09-21 GR GR20000402158T patent/GR3034469T3/el unknown
-
2012
- 2012-09-18 FR FR12C0053C patent/FR12C0053I2/fr active Active
-
2013
- 2013-06-10 LU LU92209C patent/LU92209I2/fr unknown
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