FI973183A0 - Diagnostiseen kuvantamiseen soveltuvia varjoaineita, joilla on pidentynyt viipymä veressä - Google Patents
Diagnostiseen kuvantamiseen soveltuvia varjoaineita, joilla on pidentynyt viipymä veressäInfo
- Publication number
- FI973183A0 FI973183A0 FI973183A FI973183A FI973183A0 FI 973183 A0 FI973183 A0 FI 973183A0 FI 973183 A FI973183 A FI 973183A FI 973183 A FI973183 A FI 973183A FI 973183 A0 FI973183 A0 FI 973183A0
- Authority
- FI
- Finland
- Prior art keywords
- blood
- contrast agents
- diagnostic imaging
- agents suitable
- prolonged residence
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
- A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
- A61K49/085—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier conjugated systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/0002—General or multifunctional contrast agents, e.g. chelated agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
- A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
- A61K49/10—Organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
- A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
- A61K49/10—Organic compounds
- A61K49/101—Organic compounds the carrier being a complex-forming compound able to form MRI-active complexes with paramagnetic metals
- A61K49/103—Organic compounds the carrier being a complex-forming compound able to form MRI-active complexes with paramagnetic metals the complex-forming compound being acyclic, e.g. DTPA
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
- A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
- A61K49/10—Organic compounds
- A61K49/101—Organic compounds the carrier being a complex-forming compound able to form MRI-active complexes with paramagnetic metals
- A61K49/106—Organic compounds the carrier being a complex-forming compound able to form MRI-active complexes with paramagnetic metals the complex-forming compound being cyclic, e.g. DOTA
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/06—Phosphorus compounds without P—C bonds
- C07F9/08—Esters of oxyacids of phosphorus
- C07F9/09—Esters of phosphoric acids
- C07F9/091—Esters of phosphoric acids with hydroxyalkyl compounds with further substituents on alkyl
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B6/00—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment
- A61B6/50—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment specially adapted for specific body parts; specially adapted for specific clinical applications
- A61B6/507—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment specially adapted for specific body parts; specially adapted for specific clinical applications for determination of haemodynamic parameters, e.g. perfusion CT
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Radiology & Medical Imaging (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Magnetic Resonance Imaging Apparatus (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Apparatus For Radiation Diagnosis (AREA)
- Ultra Sonic Daignosis Equipment (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US38231795A | 1995-02-01 | 1995-02-01 | |
| PCT/US1996/000164 WO1996023526A2 (en) | 1995-02-01 | 1996-01-16 | Diagnostic imaging contrast agents with extended blood retention |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| FI973183A0 true FI973183A0 (fi) | 1997-07-31 |
| FI973183L FI973183L (fi) | 1997-07-31 |
| FI973183A7 FI973183A7 (fi) | 1997-07-31 |
Family
ID=23508434
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI973183A FI973183A7 (fi) | 1995-02-01 | 1996-01-16 | Diagnostiseen kuvantamiseen soveltuvia varjoaineita, joilla on pidenty nyt viipymä veressä |
Country Status (24)
Families Citing this family (112)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW319763B (cg-RX-API-DMAC10.html) * | 1995-02-01 | 1997-11-11 | Epix Medical Inc | |
| US6713045B1 (en) | 1995-06-02 | 2004-03-30 | Research Corporation Technologies, Inc. | Targeted magnetic resonance imaging agents for the detection of physiological processes |
| US6770261B2 (en) | 1995-06-02 | 2004-08-03 | Research Corporation Technologies | Magnetic resonance imaging agents for the detection of physiological agents |
| DE19543077C2 (de) * | 1995-11-13 | 1997-10-16 | Schering Ag | Verwendung von gashaltigen Metallkomplexen als Ultraschallkontrastmittel |
| PT907379E (pt) | 1996-04-01 | 2004-09-30 | Epix Medical Inc | Agentes de contraste bioactivados para imagiologia de diagnostico |
| US5900228A (en) | 1996-07-31 | 1999-05-04 | California Institute Of Technology | Bifunctional detection agents having a polymer covalently linked to an MRI agent and an optical dye |
| US5919967A (en) * | 1997-04-11 | 1999-07-06 | Epix Medical, Inc. | Process for synthesizing phosphodiesters |
| US6495118B1 (en) | 1997-09-26 | 2002-12-17 | Schering Aktiengesellschaft | Lipophilic metal complexes for necrosis and infarction imaging |
| DE19744004C1 (de) * | 1997-09-26 | 1999-07-22 | Schering Ag | Lipophile Metall-Komplexe für Nekrose und Infarkt-Imaging |
| CA2303426C (en) * | 1997-10-02 | 2008-09-23 | Epix Medical, Inc. | Contrast-enhanced diagnostic imaging method for monitoring interventional therapies |
| JP2001521011A (ja) * | 1997-10-27 | 2001-11-06 | カリフォルニア・インスティテュート・オブ・テクノロジー | 治療成分送達のための磁気共鳴イメージング剤 |
| US6713046B1 (en) | 1997-10-27 | 2004-03-30 | Research Corporation Technologies | Magnetic resonance imaging agents for the delivery of therapeutic agents |
| EP1032430A2 (en) | 1997-11-17 | 2000-09-06 | Research Corporation Technologies, Inc. | Magnetic resonance imaging agents for the detection of physiological agents |
| GB9912356D0 (en) | 1999-05-26 | 1999-07-28 | Btg Int Ltd | Generation of microfoam |
| JP3848493B2 (ja) * | 1999-06-30 | 2006-11-22 | 英三 盛 | X線診断システム |
| HK1048952A1 (zh) | 1999-07-29 | 2003-04-25 | 埃匹克斯医学股份有限公司 | 通过多位点结合的寻靶多体造影剂 |
| DE19964224B4 (de) * | 1999-09-09 | 2005-09-01 | Schering Ag | Pharmazeutische Mittel enthaltend Calcium-Komplex von [[(4R)-4-[bis[(carboxy-.kappa.O)methyl]amino-.kappa.N]-6,9-bis[(carboxy-.kappa.O)methyl]-1-[(4,4-diphenylcyclohexyl)oxy]-1-hydroxy-2-oxa-6,9-diaza-1-phosphaundecan-11-yl-säure-.kappa.N6,.kappa.N9,.kappa.011]1-oxidato(6-)]-, tetrahydrogen (MS-325) und dessen Salze sowie Verfahren zur Herstellung der Mittel |
| DE19944893C2 (de) * | 1999-09-09 | 2001-09-20 | Schering Ag | Calcium-Komplex von [[(4R)-4-[bis[(carboxy-.kappa.O)methyl]amino-. kappa.N]-6,9-bis[(carboxy-.kappa.O)methyl]-1-[(4,4-diphenylcyclohexyl)oxy]-1-hydroxy-2-oxa-6,9-diaza-1-phosphaundecan-11-yl-säure-.kappa.N6, .kappa.N9,.kappa.O11]1-oxidato(6-)]-, hexahydrogen, dessen Salze und diese Komplexe enthaltende pharmazeutische Mittel |
| DE59900055D1 (de) * | 1999-09-09 | 2001-04-12 | Schering Ag | Calcium-Komplex von (4R)-4-bis(carboxy-kappa.O)methyl amino-.kappa.N-6,9-bis (carboxy-.kappa.O)methyl-1-(4,4-diphenylcyclohexyl)oxy-1-hydroxy-2-oxa-6,9-diaza-1-phosphaundecan-11-yl-säure-.kappa.N6,.kappa.N9,.kappa.O11 1-oxidato(6-)-,hexahydrogen, dessen Salze, diese Komplexe enthaltende pharmazeutische Mittel, deren Verwendung in der Therapie und als Zusatzstoff in der Diagnostik sowie Verfahren zur Herstellung der Komplexe und Mittel |
| US6559330B1 (en) | 1999-09-09 | 2003-05-06 | Schering Aktiengesellschaft | Calcium complex of [[(4r)-4-[bis{carboxy-.kappa.o)methyl]amino-.kappa.n]-6,9-bis[(carboxy.kappa.o)methyl]-1-[(4,4-diphenylcyclohexyl)oxy]-1-hydroxy-2-oxa-6,9-diaza-1-phosphaundecan-11-ylic-acid-.kappa.n6,.kappa.n9,.kappa.011]1-oxidato(6-)]-, hexahydrogen, its salts, pharmaceutical agents that contain these complexes, their use in treatment and as additives in diagnosis, as well as processes for the production of the complexes and agents |
| US20030203879A1 (en) * | 1999-09-09 | 2003-10-30 | Schering Ag | Calcium complex of [[(4R)-4-[bis[(carboxy-.kappa.O)methyl]amino-.kappa.n]-6,9-bis[(carboxy.kappa.O)methyl]-1-[(4,4-diphenylcyclohexy)oxy]-1-hydroxy-2-oxa-6,9-diaza-1-phosphaundecan-11-ylic-acid-.kappa.N6,.Kappa.N9,.Kappa 011]1-oxidato(6-)]-, hexahydrogen, its salts, pharmaceutical agents that contain these complexes, their use in treatment and as additives in diagnosis, as well as processes for the production of the complexes and agents |
| EP1237593A1 (en) | 1999-11-22 | 2002-09-11 | Epix Medical, Inc. | Imaging sexual response |
| US20030082106A1 (en) * | 2000-01-22 | 2003-05-01 | Aleksandr Nivorozhkin | Magnetic resonance imaging using contrast agents bioactivated by enzymatic cleavage |
| US6673333B1 (en) | 2000-05-04 | 2004-01-06 | Research Corporation Technologies, Inc. | Functional MRI agents for cancer imaging |
| US6656450B2 (en) | 2000-07-17 | 2003-12-02 | California Institute Of Technology, Inc. | Macrocyclic magnetic resonance imaging contrast agents |
| WO2002028441A2 (en) | 2000-10-04 | 2002-04-11 | California Institute Of Technology | Magnetic resonance imaging agents for in vivo labeling and detection of amyloid deposits |
| US6549798B2 (en) | 2001-02-07 | 2003-04-15 | Epix Medical, Inc. | Magnetic resonance angiography data |
| TWI221406B (en) | 2001-07-30 | 2004-10-01 | Epix Medical Inc | Systems and methods for targeted magnetic resonance imaging of the vascular system |
| TWI240632B (en) | 2001-07-30 | 2005-10-01 | Epix Medical Inc | Purified peptides for peptide-based multimeric targeted contrast agents |
| US8512680B2 (en) | 2001-08-08 | 2013-08-20 | Btg International Ltd. | Injectables in foam, new pharmaceutical applications |
| US7186797B2 (en) * | 2001-08-10 | 2007-03-06 | Epix Pharmaceuticals, Inc. | Polypeptide conjugates with extended circulating half-lives |
| WO2003029257A1 (de) * | 2001-09-27 | 2003-04-10 | Schering Aktiengesellschaft | (ethylen)-(propylen/butylen)-phosphodiester-triaminpentaessigsäure-derivate |
| US8623822B2 (en) | 2002-03-01 | 2014-01-07 | Bracco Suisse Sa | KDR and VEGF/KDR binding peptides and their use in diagnosis and therapy |
| US7794693B2 (en) | 2002-03-01 | 2010-09-14 | Bracco International B.V. | Targeting vector-phospholipid conjugates |
| US7261876B2 (en) | 2002-03-01 | 2007-08-28 | Bracco International Bv | Multivalent constructs for therapeutic and diagnostic applications |
| US20050100963A1 (en) | 2002-03-01 | 2005-05-12 | Dyax Corporation | KDR and VEGF/KDR binding peptides and their use in diagnosis and therapy |
| SI2301587T1 (sl) | 2002-03-01 | 2014-11-28 | Dyax Corp. | KDR in VEGF/KDR vezavni peptidi in njihova uporaba pri diagnozi |
| US7226577B2 (en) | 2003-01-13 | 2007-06-05 | Bracco Imaging, S. P. A. | Gastrin releasing peptide compounds |
| AU2004217894B2 (en) | 2003-03-03 | 2010-07-15 | Bracco International B.V. | Peptides that specifically bind HGF receptor (cMet) and uses thereof |
| CA2526760A1 (en) | 2003-05-23 | 2005-01-06 | Epix Pharmaceuticals, Inc. | Optically pure and enriched isomers of chelating ligands and contrast agents |
| US7251520B2 (en) * | 2003-07-08 | 2007-07-31 | General Electric Company | Method and apparatus of slice selective magnetization preparation for moving table MRI |
| AR047692A1 (es) * | 2003-07-10 | 2006-02-08 | Epix Medical Inc | Imagenes de blancos estacionarios |
| CA2445420A1 (en) | 2003-07-29 | 2005-01-29 | Invitrogen Corporation | Kinase and phosphatase assays |
| US7619059B2 (en) | 2003-07-29 | 2009-11-17 | Life Technologies Corporation | Bimolecular optical probes |
| US8048439B2 (en) | 2003-11-17 | 2011-11-01 | Btg International Ltd. | Therapeutic foam |
| EP1684718A1 (en) | 2003-11-17 | 2006-08-02 | Btg International Limited | Methods of preparing a foam comprising a sclerosing agent |
| US7189879B2 (en) | 2004-05-25 | 2007-03-13 | Schering Ag | Process for the production of 1-hydroxymethyl-1,3,5-triazapentane, trihydrochloride |
| DE102004026102B4 (de) * | 2004-05-25 | 2006-08-24 | Schering Ag | Verfahren zur Herstellung von 1-Hydroxymethyl-1,3,5-triazapentan, Trihydrochlorid |
| EP1768558A4 (en) * | 2004-06-09 | 2009-11-25 | Kereos Inc | LIPOPHILES DERIVATIVES OF CHELATE MONOAMIDES |
| DE102004062258B3 (de) * | 2004-12-23 | 2006-01-05 | Schering Ag | Hydroxypyridinon-Derivate, deren Metallkomplexe und deren Verwendung zur Herstellung von Konjugaten mit Biomolekülen |
| EP1845840B1 (en) | 2005-01-26 | 2018-05-30 | The Regents of the University of Colorado | Methods for diagnosis and intervention of hepatic disorders |
| US8778299B2 (en) | 2005-01-26 | 2014-07-15 | The Regents Of The University Of Colorado, A Body Corporate | Methods for diagnosis and intervention of hepatic disorders |
| WO2006084257A2 (en) * | 2005-02-03 | 2006-08-10 | Epix Pharmaceuticals, Inc. | Steady state perfusion methods |
| JP2006248978A (ja) | 2005-03-10 | 2006-09-21 | Mebiopharm Co Ltd | 新規なリポソーム製剤 |
| GB0509824D0 (en) | 2005-05-13 | 2005-06-22 | Btg Int Ltd | Therapeutic foam |
| WO2007002109A2 (en) * | 2005-06-20 | 2007-01-04 | The Regents Of The University Of California | Multidentate pyrone-derived chelators for medicinal imaging and chelation |
| KR100762357B1 (ko) * | 2005-06-28 | 2007-10-05 | 원광대학교산학협력단 | 염증특이적 엠알 조영제 및 이의 제조방법 |
| KR100762359B1 (ko) * | 2005-06-28 | 2007-10-05 | 원광대학교산학협력단 | 신생혈관특이적 엠알 조영제 및 이의 제조방법 |
| US9339559B2 (en) * | 2005-09-09 | 2016-05-17 | Georgia State University Research Foundation, Inc. | Targeted contrast agents and methods for targeting contrast agents |
| WO2007009058A2 (en) * | 2005-07-13 | 2007-01-18 | Georgia State University Research Foundation, Inc. | Contrast agents and methods for preparing contrast agents |
| WO2007073792A1 (de) * | 2005-12-19 | 2007-07-05 | Bayer Schering Pharma Aktiengesellschaft | Verfahren zur herstellung von 4,4-diphenylcyclohexanol |
| WO2007084264A2 (en) | 2005-12-29 | 2007-07-26 | Epix Pharmaceuticals, Inc. | Methods for myocardial imaging |
| DE102006025940B4 (de) * | 2006-06-02 | 2009-11-05 | Siemens Ag | Dielektrisches Element, Verfahren zur Erzeugung von Magnetresonanzaufnahmen eines Untersuchungsobjekts und Verwendung des dielektrischen Elements |
| EP2518155B1 (en) | 2006-08-04 | 2014-07-23 | Georgia State University Research Foundation, Inc. | Enzyme sensors, methods for preparing and using such sensors, and methods of detecting protease activity |
| CA2660717A1 (en) * | 2006-08-17 | 2008-02-21 | Epix Pharmaceuticals, Inc. | Methods for lymph system imaging |
| EP2097507B1 (en) * | 2006-12-14 | 2015-05-06 | Georgia State University Research Foundation, Inc. | Analyte sensors and use thereof for detecting analyte activity |
| DE102007002726A1 (de) * | 2007-01-18 | 2008-07-31 | Bayer Schering Pharma Aktiengesellschaft | Neue Kaskaden-Polymer-Komplexe, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Mittel |
| WO2008108163A1 (ja) * | 2007-03-06 | 2008-09-12 | Konica Minolta Holdings, Inc. | ガドリニウム化合物及びmri用造影剤 |
| EP1982733A1 (en) * | 2007-04-17 | 2008-10-22 | Bayer Schering Pharma Aktiengesellschaft | Use of a contrast agent for magnetic resonance imaging of endoleaks |
| WO2008144728A1 (en) * | 2007-05-21 | 2008-11-27 | Bracco Imaging S.P.A. | Conjugates which bind a blood protein such as human serum albumin and methods of using the same in diagnostic and therapeutic applications |
| CN103965128B (zh) | 2008-01-08 | 2018-04-03 | 兰休斯医疗成像公司 | 作为显像剂的n‑烷氧基酰胺共轭物 |
| EP3498307A1 (en) | 2008-04-02 | 2019-06-19 | Georgia State University Research Foundation, Inc. | Contrast agents, methods for preparing contrast agents, and methods of imaging |
| WO2010107832A1 (en) | 2009-03-17 | 2010-09-23 | Bracco Imaging Spa | Lhrh-ii peptide analogs |
| WO2010121133A2 (en) | 2009-04-17 | 2010-10-21 | The General Hospital Corporation | Multimodal imaging of fibrin |
| JP2012521352A (ja) | 2009-03-19 | 2012-09-13 | ワイス・エルエルシー | [2−(8,9−ジオキソ−2,6−ジアザビシクロ[5.2.0]ノナ−1(7)−エン−2−イル)エチル]ホスホン酸およびその前駆体を調製するための方法 |
| US8877157B2 (en) | 2009-07-08 | 2014-11-04 | Lantheus Medical Imaging, Inc. | N-alkoxyamide conjugates as imaging agents |
| US20110071403A1 (en) * | 2009-09-21 | 2011-03-24 | Board Of Regents Of The University Of Texas System | Functional near-infrared fluorescence lymphatic mapping for diagnosing, accessing, monitoring and directing therapy of lymphatic disorders |
| WO2011041470A2 (en) | 2009-09-30 | 2011-04-07 | Mallinckrodt Inc. | Sustained-release opiate and opiate derivative compositions |
| CN102548956B (zh) | 2009-10-15 | 2014-05-14 | 国立大学法人德岛大学 | 二乙烯三胺五醋酸衍生物的制造方法及二乙烯三胺五醋酸衍生物 |
| EP2432191A1 (en) * | 2010-09-15 | 2012-03-21 | Alcatel Lucent | Methods and systems for service delivery |
| AU2012262329B2 (en) | 2011-05-31 | 2014-10-16 | The Regents Of The University Of Colorado, A Body Corporate | Method for assessment of hepatic function and portal blood flow |
| WO2013009869A2 (en) | 2011-07-11 | 2013-01-17 | Integrated Diagnostics, Inc. | Akt-specific capture agents, compositions, and methods of using and making |
| CA2862760A1 (en) | 2012-03-05 | 2013-09-12 | Bracco Imaging Spa | Dynamic contrast enhanced-mri method and agents for the assessment of the macromolecular transport within pathologic tissues |
| JP6378194B2 (ja) | 2012-11-12 | 2018-08-22 | ザ リージェンツ オブ ザ ユニヴァーシティ オブ コロラド,ア ボディ コーポレイト | 慢性肝疾患の評価のための疾患重症度指数および原発性硬化性胆管炎の3つの異なるサブタイプの診断方法 |
| TW201514188A (zh) * | 2013-03-13 | 2015-04-16 | Lantheus Medical Imaging Inc | 製備釓磷維塞三鈉單水合物之方法 |
| WO2015038968A1 (en) | 2013-09-13 | 2015-03-19 | The General Hospital Corporation | Activatable fibrin-binding probes |
| WO2015171543A1 (en) | 2014-05-05 | 2015-11-12 | California Institute Of Technology | Mutant akt-specific capture agents, compositions, and methods of using and making |
| US10478120B2 (en) * | 2014-05-17 | 2019-11-19 | The Johns Hopkins University | MRI-guided intraarterial catheter-based method for predicting territory of local blood brain barrier opening |
| US10471162B2 (en) | 2014-06-20 | 2019-11-12 | The General Hospital Corporation | Collagen targeted imaging probes |
| EP3270951B1 (en) | 2015-03-16 | 2020-09-09 | California Institute of Technology | Botulinum neurotoxin-specific capture agents, compositions, and methods of using and making |
| US10301358B2 (en) | 2015-06-29 | 2019-05-28 | Collagen Medical, LLC | Collagen imaging compositions |
| IL256833B2 (en) | 2015-07-15 | 2025-07-01 | California Inst Of Techn | IL-17F-specific binding agents, compositions and methods of use and preparation |
| ES2987778T3 (es) | 2015-08-13 | 2024-11-18 | Massachusetts Gen Hospital | Conjugados de quelatos a base de manganeso para la imagenología por resonancia magnética molecular |
| JP6491747B2 (ja) * | 2015-09-30 | 2019-03-27 | デューク・ユニヴァーシティ | 磁気共鳴画像法用の造影剤 |
| US20170319722A1 (en) | 2016-04-04 | 2017-11-09 | Indi Molecular, Inc. | Cd8-specific capture agents, compositions, and methods of using and making |
| EP3519425B1 (en) | 2016-09-29 | 2024-02-28 | Indi Molecular, Inc. | Compositions for detection, inhibition and imaging of indoleamine 2,3-dioxygenase 1 (ido1) and methods of making and using same |
| US11358982B2 (en) | 2016-11-01 | 2022-06-14 | Ohio State Innovation Foundation | Methods for the iodination of biomolecules |
| EP3638687A1 (en) | 2017-06-15 | 2020-04-22 | Indi Molecular, Inc. | Il-17f and il-17a-specific capture agents, compositions, and methods of using and making |
| US12029790B2 (en) * | 2017-07-31 | 2024-07-09 | Ohio State Innovation Foundation | Biomimetic nanomaterials and uses thereof |
| US10933146B2 (en) | 2017-12-12 | 2021-03-02 | Massachusetts Institute Of Technology | Cell-permeable imaging sensors and uses thereof |
| TWI667996B (zh) | 2018-03-23 | 2019-08-11 | 中國醫藥大學附設醫院 | 乳房腫瘤輔助檢測模型及乳房腫瘤輔助檢測系統 |
| US11919972B2 (en) | 2018-11-02 | 2024-03-05 | Regeneron Pharmaceuticals, Inc. | Peptide libraries with non-canonical amino acids |
| WO2020097531A1 (en) | 2018-11-08 | 2020-05-14 | Indi Molecular, Inc. | Theranostic capture agents, compositions, and methods of using and making |
| WO2020186091A1 (en) | 2019-03-12 | 2020-09-17 | Indi Molecular, Inc. | Cross-linked epitopes and methods of use thereof |
| US12201679B2 (en) | 2019-04-05 | 2025-01-21 | Institute For Systems Biology | Epitope-targeted peptide immunostimulants |
| EP3972646A4 (en) | 2019-05-20 | 2023-06-14 | Ohio State Innovation Foundation | Apohemoglobin-haptoglobin complexes and methods of using thereof |
| WO2020236969A1 (en) | 2019-05-20 | 2020-11-26 | Indi Molecular, Inc. | Compositions and methods relating to detection, inhibition, and imaging of indoleamine 2,3-dioxygenase 1 (ido1) |
| US11414460B2 (en) | 2019-07-19 | 2022-08-16 | Institute For Systems Biology | KRAS-specific capture agents, compositions, and methods of making and using |
| BR112022022045A2 (pt) | 2020-04-30 | 2023-01-10 | Sairopa B V | Anticorpo ou fragmento de ligação ao antígeno do mesmo que se liga ao cd103 humano, um ou mais ácidos nucleicos, sistema de expressão, célula hospedeira, composição, métodos de produção de um anticorpo ou fragmento de ligação ao antígeno, para detectar a presença de cd103 em uma amostra biológica, para tratar ou prevenir uma condição mediada por sinalização de cd103 em um indivíduo em necessidade, para inibir a sinalização de cd103 em uma célula, para inibir a ligação de cd103 à e-caderina presente em uma célula, para retirar as células que expressam cd103 em um indivíduo, para tratar ou prevenir uma doença e agente de imageamento |
| US12209142B2 (en) | 2020-05-29 | 2025-01-28 | Institute For Systems Biology | SARS-CoV-2 epitope-targeted peptide immunostimulants |
| WO2022098745A1 (en) | 2020-11-03 | 2022-05-12 | Indi Molecular, Inc. | Compositions, delivery systems, and methods useful in tumor therapy |
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Family Cites Families (102)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US488008A (en) * | 1892-12-13 | Method of forming dental crowns | ||
| DE450742C (de) | 1924-12-04 | 1927-10-15 | Arthur Korn Dr | Verfahren zur drahtlosen UEbertragung von Bildern |
| US3632637A (en) | 1968-02-13 | 1972-01-04 | Arthur E Martell | Hydroxyaryl-containing aminocarboxylic chelating agents |
| US4088747A (en) | 1975-02-19 | 1978-05-09 | Australian Atomic Energy Commission | Phenolic amino-carboxylic acid radiopharmaceuticals |
| FR2354993A1 (fr) | 1976-06-16 | 1978-01-13 | Dabeer | Procede pour la preparation de derives phenoliques d'acides hydroxyalcoyl-alcoylene-diaminoacetiques et de leurs sels |
| US4150047A (en) | 1978-03-06 | 1979-04-17 | Air Products And Chemicals, Inc. | Process for preparing halogenated metal chelates |
| IN152852B (cg-RX-API-DMAC10.html) * | 1978-08-09 | 1984-04-21 | Gen Electric Co Ltd | |
| US4352751A (en) | 1979-09-10 | 1982-10-05 | Analytical Radiation Corporation | Species-linked diamine triacetic acids and their chelates |
| US4308249A (en) | 1979-12-13 | 1981-12-29 | G. D. Searle & Co. | Radiopharmaceutical complexes of N-(tri-substituted alkyl)-iminodiacetic acids |
| US4331647A (en) | 1980-03-03 | 1982-05-25 | Goldenberg Milton David | Tumor localization and therapy with labeled antibody fragments specific to tumor-associated markers |
| US4361544A (en) | 1980-03-03 | 1982-11-30 | Goldenberg Milton David | Tumor localization and therapy with labeled antibodies specific to intracellular tumor-associated markers |
| US4401647A (en) | 1980-03-03 | 1983-08-30 | The Regents Of The University Of Ca | Radiolabeled neoglycopeptides |
| US4308149A (en) | 1980-07-14 | 1981-12-29 | Nalco Chemical Company | Branched/cross-linked cationic phenol-formaldehyde polymers useful in wastewater treatment |
| US4647447A (en) | 1981-07-24 | 1987-03-03 | Schering Aktiengesellschaft | Diagnostic media |
| DE3129906C3 (de) | 1981-07-24 | 1996-12-19 | Schering Ag | Paramagnetische Komplexsalze, deren Herstellung und Mittel zur Verwendung bei der NMR-Diagnostik |
| US4957939A (en) | 1981-07-24 | 1990-09-18 | Schering Aktiengesellschaft | Sterile pharmaceutical compositions of gadolinium chelates useful enhancing NMR imaging |
| US4472509A (en) | 1982-06-07 | 1984-09-18 | Gansow Otto A | Metal chelate conjugated monoclonal antibodies |
| NL194579C (nl) | 1983-01-21 | 2002-08-05 | Schering Ag | Diagnostisch middel. |
| FR2550449B1 (fr) | 1983-08-12 | 1986-01-31 | Commissariat Energie Atomique | Agents de relaxation specifiques d'organes ou de pathologies, utilisables pour modifier les contrastes en imagerie medicale par resonance magnetique nucleaire |
| US4615879A (en) | 1983-11-14 | 1986-10-07 | Vanderbilt University | Particulate NMR contrast agents for gastrointestinal application |
| SE463651B (sv) | 1983-12-21 | 1991-01-07 | Nycomed As | Diagnostikum och kontrastmedel |
| GB8413772D0 (en) | 1984-05-30 | 1984-07-04 | Nyegaard & Co As | Chemical compounds |
| GB8413849D0 (en) | 1984-05-31 | 1984-07-04 | Amersham Int Plc | Nmr contrast agents |
| CA1260827A (en) | 1984-08-31 | 1989-09-26 | Richard C. Siegel | Antibody-metal ion complexes |
| US4859451A (en) | 1984-10-04 | 1989-08-22 | Salutar, Inc. | Paramagnetic contrast agents for MR imaging |
| US4687658A (en) | 1984-10-04 | 1987-08-18 | Salutar, Inc. | Metal chelates of diethylenetriaminepentaacetic acid partial esters for NMR imaging |
| US4687659A (en) | 1984-11-13 | 1987-08-18 | Salutar, Inc. | Diamide-DTPA-paramagnetic contrast agents for MR imaging |
| US4639365A (en) | 1984-10-18 | 1987-01-27 | The Board Of Regents, The University Of Texas System | Gadolinium chelates as NMR contrast agents |
| US4746507A (en) | 1985-04-02 | 1988-05-24 | Salutar, Inc. | EDHPA based contrast agents for MR imaging, apparatus and methods |
| US4899755A (en) | 1985-05-08 | 1990-02-13 | The General Hospital Corporation | Hepatobiliary NMR contrast agents |
| US5250285A (en) | 1985-05-08 | 1993-10-05 | The General Hospital Corporation | Hydroxy-aryl metal chelates for diagnostic NMR imaging |
| US4880008A (en) | 1985-05-08 | 1989-11-14 | The General Hospital Corporation | Vivo enhancement of NMR relaxivity |
| US5525338A (en) | 1992-08-21 | 1996-06-11 | Immunomedics, Inc. | Detection and therapy of lesions with biotin/avidin conjugates |
| US5512332A (en) | 1985-10-04 | 1996-04-30 | Immunivest Corporation | Process of making resuspendable coated magnetic particles |
| US5017359A (en) | 1985-11-01 | 1991-05-21 | Centre National De La Recherche Scientifique | Aerosol compositions for in vivo imaging and therapy |
| US5223242A (en) * | 1985-11-05 | 1993-06-29 | The General Hospital Corporation | Negatively charged specific affinity reagents |
| FI72080C (fi) | 1986-01-17 | 1987-04-13 | Erkki Tapio Tuhkanen | Upphaengningsfaeste av foervaringsroer foer dokument. |
| DE3772785D1 (de) | 1986-01-23 | 1991-10-17 | Squibb & Sons Inc | 1-substituiertes-4,7,10-triscarboxymethyl-1,4,7,10-tetraazacyclododecan und analoga. |
| MX174467B (es) | 1986-01-23 | 1994-05-17 | Squibb & Sons Inc | 1,4,7-triscarboximetil-1,4,7,10-tetraazaciclodo decano substituido en 1 y compuestos analogos |
| US4885363A (en) | 1987-04-24 | 1989-12-05 | E. R. Squibb & Sons, Inc. | 1-substituted-1,4,7-triscarboxymethyl-1,4,7,10-tetraazacyclododecane and analogs |
| IT1213029B (it) | 1986-01-30 | 1989-12-07 | Bracco Ind Chimica Spa | Chelati di ioni metallici paramagnetici. |
| US4834964A (en) | 1986-03-07 | 1989-05-30 | M.R.I., Inc. | Use of charged nitroxides as NMR image enhancing agents for CSF |
| EP0250358A3 (en) | 1986-06-20 | 1988-10-05 | Schering Aktiengesellschaft | Novel complex compounds |
| US5314679A (en) | 1986-07-03 | 1994-05-24 | Advanced Magnetics Inc. | Vascular magnetic resonance imaging agent comprising nanoparticles |
| AU608759B2 (en) | 1986-08-04 | 1991-04-18 | Amersham Health Salutar Inc | NMR imaging with paramagnetic polyvalents metal salts of poly-(acid-alkylene-amido)-alkanes |
| JPS6390586A (ja) * | 1986-09-29 | 1988-04-21 | リ−・フア−マス−テイカルズ・インコ−ポレイテツド | 改良された接着タブ系 |
| US5057302A (en) | 1987-02-13 | 1991-10-15 | Abbott Laboratories | Bifunctional chelating agents |
| DE3710730A1 (de) | 1987-03-31 | 1988-10-20 | Schering Ag | Substituierte komplexbildner, komplexe und komplexsalze, verfahren zu deren herstellung und diese enthaltende pharmazeutische mittel |
| US4842845A (en) | 1987-05-08 | 1989-06-27 | Salutar, Inc. | Radioactive metal chelates for dipyridoxyl phosphate |
| US4935518A (en) | 1987-05-08 | 1990-06-19 | Salutar, Inc. | Manganese(II), chelate contrast agents derived from N,N'-bis-(pyridoxal ethylene diamine-N,N')-diacetic acid and derivatives thereof |
| US5223243A (en) | 1987-05-08 | 1993-06-29 | Salutar, Inc. | Dipyridoxyl phosphate chelating compound intermediates useful as NMRI contrast agents |
| AR246956A1 (es) | 1987-05-08 | 1994-10-31 | Salutar Inc | Compuesto quelante, un intermediario para preparar el mismo, y un procedimiento para preparar una composicion de medio de contraste. |
| US5091169A (en) * | 1987-05-08 | 1992-02-25 | Salutar, Inc. | Dipyridoxyl phosphate NMRI contrast agent compositions |
| GB8719042D0 (en) | 1987-08-12 | 1987-09-16 | Parker D | Conjugate compounds |
| GB8719041D0 (en) | 1987-08-12 | 1987-09-16 | Parker D | Conjugate compounds |
| DE3728600A1 (de) | 1987-08-27 | 1989-03-09 | Hoechst Ag | Verfahren zur markierung von substanzen mit technetium oder rhenium |
| US5635180A (en) | 1988-02-17 | 1997-06-03 | Neorx Corporation | Alteration of pharmacokinetics of proteins by charge modification |
| DE3806795A1 (de) | 1988-02-29 | 1989-09-07 | Schering Ag | Polymer-gebundene komplexbildner, deren komplexe und konjugate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische mittel |
| US5513332A (en) | 1988-05-31 | 1996-04-30 | Extended Systems, Inc. | Database management coprocessor for on-the-fly providing data from disk media to all without first storing data in memory therebetween |
| KR0130770B1 (ko) | 1988-06-24 | 1998-04-17 | 나가이 아쯔시 | 테이프 카트리지 |
| NZ229700A (en) | 1988-06-24 | 1993-01-27 | Dow Chemical Co | Tetraazacyclododecane derivatives containing a linker/spacer moiety capable of forming antibody conjugates; complexes with radionuclides and conjugates of such compounds and complexes with antibodies or antibody fragments |
| DE3825278A1 (de) * | 1988-07-26 | 1990-02-01 | Basf Lacke & Farben | Verfahren zur herstellung von mehrschichtigen, schuetzenden und/oder dekorativen ueberzuegen auf substratoberflaechen |
| JP2854905B2 (ja) | 1988-09-27 | 1999-02-10 | サリユーター・インコーポレイテツド | キレート組成物 |
| JP2930708B2 (ja) | 1988-12-23 | 1999-08-03 | ザ ダウ ケミカル カンパニー | イソチオシアナト官能化金属錯体の製造方法 |
| US5078986A (en) | 1989-02-15 | 1992-01-07 | Mallinckrodt Medical, Inc. | Method for enhancing magnetic resonance imaging using an image altering agent containing an excess of chelating agent |
| FR2643370B1 (fr) | 1989-02-22 | 1991-08-23 | Air Liquide | Derives polyazotes et leurs complexes metalliques utilisables pour la fixation de l'oxygene |
| US5094848A (en) | 1989-06-30 | 1992-03-10 | Neorx Corporation | Cleavable diphosphate and amidated diphosphate linkers |
| US5695739A (en) * | 1989-06-30 | 1997-12-09 | Schering Aktiengesellschaft | Derivatized DTPA complexes, pharmaceutical agents containing these compounds, their use, and processes for their production |
| DE3922005A1 (de) | 1989-06-30 | 1991-01-10 | Schering Ag | Derivatisierte dtpa-komplexe, diese verbindungen enthaltende pharmazeutische mittel, ihre verwendung und verfahren zu deren herstellung |
| CA2065290C (en) * | 1989-08-28 | 2000-12-12 | Randall B. Lauffer | Hydroxy-aryl metal chelates for diagnostic nmr imaging |
| EP0418419B1 (de) * | 1989-09-22 | 1994-12-14 | Deutsche ITT Industries GmbH | Zweiphasentaktgenerator |
| IN172208B (cg-RX-API-DMAC10.html) | 1990-04-02 | 1993-05-01 | Sint Sa | |
| GB9007431D0 (en) | 1990-04-03 | 1990-05-30 | Shell Int Research | Diesel fuel additives |
| DE4011684A1 (de) | 1990-04-06 | 1991-10-10 | Schering Ag | Dtpa-monoamide, diese verbindungen enthaltende pharmazeutische mittel, ihre verwendung und verfahren zu deren herstellung |
| WO1991016081A1 (en) | 1990-04-18 | 1991-10-31 | Celltech Limited | Tetra-aza macrocycles, processes for their preparation and their use in magnetic resonance imaging |
| CA2039399C (en) | 1990-04-25 | 2000-09-05 | C. Allen Chang | Dual functioning excipient for metal chelate contrast agents |
| ES2068587T3 (es) * | 1990-05-30 | 1995-04-16 | Deutsches Krebsforsch | Medicamentos tumorales sustituidos con polieter. |
| US5487390A (en) | 1990-10-05 | 1996-01-30 | Massachusetts Institute Of Technology | Gas-filled polymeric microbubbles for ultrasound imaging |
| DE4035760A1 (de) | 1990-11-08 | 1992-05-14 | Schering Ag | Mono-n-substituierte 1,4,7,10-tetraazacyclododecan-derivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische mittel |
| TW213864B (cg-RX-API-DMAC10.html) | 1991-08-01 | 1993-10-01 | Squibb & Sons Inc | |
| WO1993003351A1 (en) | 1991-08-09 | 1993-02-18 | The Regents Of The University Of California | Amino acid, ester and/or catechol contrast agents for mri |
| US5385719A (en) * | 1991-09-24 | 1995-01-31 | Unger; Evan C. | Copolymers and their use as contrast agents in magnetic resonance imaging and in other applications |
| JP2894879B2 (ja) * | 1991-10-04 | 1999-05-24 | 日本メジフィジックス株式会社 | 診断用造影剤 |
| US5407659A (en) | 1991-10-22 | 1995-04-18 | Mallinckrodt Medical, Inc. | Treated calcium/oxyanion-containing particles for medical diagnostic imaging |
| US5464696A (en) | 1992-08-13 | 1995-11-07 | Bracco International B.V. | Particles for NMR imaging |
| US5362478A (en) | 1993-03-26 | 1994-11-08 | Vivorx Pharmaceuticals, Inc. | Magnetic resonance imaging with fluorocarbons encapsulated in a cross-linked polymeric shell |
| US5318769A (en) | 1993-03-31 | 1994-06-07 | Sterling Winthrop Inc. | Compositions of iodophenyl esters for X-ray visualization of the gastrointestinal tract |
| US5365180A (en) * | 1993-04-16 | 1994-11-15 | National Semiconductor Corporation | Method for measuring contact resistance |
| EP0703790B1 (en) | 1993-06-02 | 2000-08-16 | BRACCO S.p.A. | Iodinated paramagnetic chelates, and their use as contrast agents |
| US5358704A (en) | 1993-09-30 | 1994-10-25 | Bristol-Myers Squibb | Hepatobiliary tetraazamacrocyclic magnetic resonance contrast agents |
| DE4341724A1 (de) | 1993-12-03 | 1995-06-08 | Schering Ag | Halogenaryl-substituierte Metallkomplexe enthaltende pharmazeutische Mittel, deren Verwendung in der Diagnostik, sowie Verfahren zur Herstellung der Komplexe und Mittel |
| ATE199550T1 (de) * | 1993-12-30 | 2001-03-15 | Guerbet Sa | Polyaminierte liganden, metallkomplexe, verfahren zur herstellung und diagnostische und therapeutische verwendungen |
| NO940115D0 (no) | 1994-01-13 | 1994-01-13 | Nycomed Imaging As | Kontrastmidler for roentgen- og magnettomografisk avbildning |
| WO1995027705A1 (en) | 1994-04-08 | 1995-10-19 | Bracco International B.V. | Aromatic amide compounds and metal chelates thereof |
| GB9407435D0 (en) | 1994-04-14 | 1994-06-08 | Nycomed Salutar Inc | Compounds |
| IT1269839B (it) | 1994-05-26 | 1997-04-15 | Bracco Spa | Coniugati di acidi biliari, loro derivati con complessi metallici e relativi usi |
| TW319763B (cg-RX-API-DMAC10.html) * | 1995-02-01 | 1997-11-11 | Epix Medical Inc | |
| IT1283650B1 (it) | 1996-08-02 | 1998-04-23 | Bracco Spa | Chelati paramagnetici ad alta relassivita' in siero |
| US6342598B1 (en) | 1998-11-26 | 2002-01-29 | Bracco International B.V. | Amphipatic polycarboxylic chelates and complexes with paramagnetic metals as MRI contrast agents |
| IT1304501B1 (it) | 1998-12-23 | 2001-03-19 | Bracco Spa | Uso di derivati di acidi biliari coniugati con complessi metallicicome "blood pool agents" per l'indagine diagnostica tramite risonanza |
| HK1048952A1 (zh) | 1999-07-29 | 2003-04-25 | 埃匹克斯医学股份有限公司 | 通过多位点结合的寻靶多体造影剂 |
| IT1313617B1 (it) | 1999-08-31 | 2002-09-09 | Bracco Spa | Processo per la preparazione di derivati degli acidi biliari. |
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