US4851424A
(en)
*
|
1986-06-06 |
1989-07-25 |
Ciba-Geigy Corporation |
1-Phenyl-lower alkyl-imidazole 4- or 5-carboxamide compounds which are useful in the treatment of epilepsy
|
US5138069A
(en)
*
|
1986-07-11 |
1992-08-11 |
E. I. Du Pont De Nemours And Company |
Angiotensin II receptor blocking imidazoles
|
US4851423A
(en)
*
|
1986-12-10 |
1989-07-25 |
Schering Corporation |
Pharmaceutically active compounds
|
CA1329614C
(en)
*
|
1987-05-02 |
1994-05-17 |
Rainer Buerstinghaus |
N-substituted azoles
|
US4820843A
(en)
*
|
1987-05-22 |
1989-04-11 |
E. I. Du Pont De Nemours And Company |
Tetrazole intermediates to antihypertensive compounds
|
US5189048A
(en)
*
|
1988-01-07 |
1993-02-23 |
E. I. Du Pont De Nemours And Company |
Substituted 1,2,3 triazole angiotensin II antagonists
|
US5315013A
(en)
*
|
1988-01-07 |
1994-05-24 |
E. I. Du Pont De Nemours And Company |
Substituted pyrazole angiotensin II antagonists
|
US5081127A
(en)
*
|
1988-01-07 |
1992-01-14 |
E. I. Du Pont De Nemours And Company |
Substituted 1,2,3-triazole angiotensin II antagonists
|
CA1338238C
(en)
*
|
1988-01-07 |
1996-04-09 |
David John Carini |
Angiotensin ii receptor blocking imidazoles and combinations thereof with diuretics and nsaids
|
US5015651A
(en)
*
|
1988-01-07 |
1991-05-14 |
E. I. Du Pont De Nemours And Company |
Treatment of hypertension with 1,2,4-angiotensin II antagonists
|
US5210079A
(en)
*
|
1988-01-07 |
1993-05-11 |
E. I. Du Pont De Nemours And Company |
Treatment of chronic renal failure with imidazole angiotensin-II receptor antagonists
|
US5354867A
(en)
*
|
1988-12-06 |
1994-10-11 |
E. I. Du Pont De Nemours And Company |
Angiotensin II receptor blocking imidazoles
|
US4916129A
(en)
*
|
1989-01-19 |
1990-04-10 |
E. I. Du Pont De Nemours And Company |
Combination β-blocking/angiotensin II blocking antihypertensives
|
DE3928177A1
(de)
*
|
1989-04-08 |
1991-02-28 |
Thomae Gmbh Dr K |
Benzimidazole, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung
|
EP0400835A1
(en)
*
|
1989-05-15 |
1990-12-05 |
Merck & Co. Inc. |
Substituted benzimidazoles as angiotensin II antagonists
|
GB8911854D0
(en)
*
|
1989-05-23 |
1989-07-12 |
Ici Plc |
Heterocyclic compounds
|
US5332744A
(en)
*
|
1989-05-30 |
1994-07-26 |
Merck & Co., Inc. |
Substituted imidazo-fused 6-membered heterocycles as angiotensin II antagonists
|
US5157026A
(en)
*
|
1989-05-30 |
1992-10-20 |
Merck & Co., Inc. |
Oxo-purines as angiotensin II antagonists
|
IL94390A
(en)
*
|
1989-05-30 |
1996-03-31 |
Merck & Co Inc |
The 6-membered trans-nitrogen-containing heterocycles are compressed with imidazo and pharmaceutical preparations containing them
|
US5064825A
(en)
*
|
1989-06-01 |
1991-11-12 |
Merck & Co., Inc. |
Angiotensin ii antagonists
|
US5185351A
(en)
*
|
1989-06-14 |
1993-02-09 |
Smithkline Beecham Corporation |
Imidazolyl-alkenoic acids useful as angiotensin II receptor antagonists
|
US5312828A
(en)
*
|
1989-06-14 |
1994-05-17 |
Finkelstein Joseph A |
Substituted imidazoles having angiotensin II receptor blocking activity
|
EP0403158A3
(en)
*
|
1989-06-14 |
1991-12-18 |
Smithkline Beecham Corporation |
Imidazolyl-alkenoic acids
|
US5418250A
(en)
*
|
1989-06-14 |
1995-05-23 |
Smithkline Beecham Corporation |
Imidazolyl-alkenoic acids useful as angiotensin II receptor antagonists
|
SG52330A1
(en)
*
|
1989-06-14 |
1998-09-28 |
Smithkline Beecham Corp |
Imidazolyl-alkenoic acids
|
ES2084702T3
(es)
*
|
1989-06-30 |
1996-05-16 |
Du Pont |
Imidazoles sustituidos utiles como inhibidores de la angiotensina ii.
|
HU215834B
(hu)
|
1989-06-30 |
1999-04-28 |
E. I. Du Pont De Nemours And Co. |
Eljárás aromás csoporttal szubsztituált imidazolszármazékok, valamint ezeket hatóanyagként tartalmazó gyógyszerkészítmények előállítására
|
US5240928A
(en)
*
|
1989-07-03 |
1993-08-31 |
Merck & Co., Inc. |
Substituted quinazolinones as angiotensin II antagonists
|
CA2020073A1
(en)
*
|
1989-07-03 |
1991-01-04 |
Eric E. Allen |
Substituted quinazolinones as angiotensin ii antagonists
|
EP0407342A3
(en)
*
|
1989-07-06 |
1991-07-10 |
Ciba-Geigy Ag |
Pyrimidine derivatives
|
EP0409332A3
(en)
*
|
1989-07-19 |
1991-08-07 |
Merck & Co. Inc. |
Substituted triazoles as angiotensin ii antagonists
|
EP0411507B1
(en)
*
|
1989-08-02 |
1994-10-26 |
Takeda Chemical Industries, Ltd. |
Pyrazole derivatives, their production and use
|
ATE117294T1
(de)
*
|
1989-08-11 |
1995-02-15 |
Ici Plc |
Chinolin-derivate, verfahren zu ihrer herstellung und ihre anwendung als arzneimittel.
|
US5100897A
(en)
*
|
1989-08-28 |
1992-03-31 |
Merck & Co., Inc. |
Substituted pyrimidinones as angiotensin ii antagonists
|
IE70593B1
(en)
*
|
1989-09-29 |
1996-12-11 |
Eisai Co Ltd |
Biphenylmethane derivative the use of it and pharmacological compositions containing same
|
US5298518A
(en)
*
|
1989-09-29 |
1994-03-29 |
Eisai Co., Ltd. |
Biphenylmethane derivative and pharmacological use
|
EP0424317A3
(en)
*
|
1989-10-19 |
1991-09-25 |
Ciba-Geigy Ag |
Pyrimidines
|
IL95975A
(en)
*
|
1989-10-24 |
1997-06-10 |
Takeda Chemical Industries Ltd |
N-benzyl- 2-alkylbenzimidazole derivatives, their production and pharmaceutical compositions containing them
|
US5250554A
(en)
*
|
1989-10-24 |
1993-10-05 |
Takeda Chemical Industries, Ltd. |
Benzimidazole derivatives useful as angiotensin II inhibitors
|
AU640417B2
(en)
*
|
1989-10-25 |
1993-08-26 |
Smithkline Beecham Corporation |
Substituted 5-((tetrazolyl)alkenyl)imidazoles
|
US5177096A
(en)
*
|
1989-10-25 |
1993-01-05 |
Smithkline Beecham Corporation |
Substituted 5-((tetrazolyl)alkenyl)imidazoles and pharmaceutical methods of use thereof
|
IL96019A0
(en)
*
|
1989-10-31 |
1991-07-18 |
Fujisawa Pharmaceutical Co |
Imidazole derivatives,processes for the preparation thereof and pharmaceutical compositions containing the same
|
CA2028925A1
(en)
*
|
1989-11-06 |
1991-05-07 |
Gerald R. Girard |
Substituted n-(imidazolyl)alkyl alanine derivatives
|
US5248689A
(en)
*
|
1989-11-06 |
1993-09-28 |
Smithkline Beecham Corporation |
Substituted N-(imidazolyl)alkyl alanine derivatives
|
PT95899A
(pt)
*
|
1989-11-17 |
1991-09-13 |
Glaxo Group Ltd |
Processo para a preparacao de derivados indole
|
IE903911A1
(en)
*
|
1989-11-20 |
1991-05-22 |
Ici Plc |
Diazine derivatives
|
US5073566A
(en)
*
|
1989-11-30 |
1991-12-17 |
Eli Lilly And Company |
Angiotensin ii antagonist 1,3-imidazoles and use thereas
|
US5104891A
(en)
*
|
1989-12-11 |
1992-04-14 |
G. D. Searle & Co. |
Cycloheptimidazolone compounds as angiotensin ii antagonists for control of hypertension
|
EP0434038A1
(en)
*
|
1989-12-22 |
1991-06-26 |
Takeda Chemical Industries, Ltd. |
Fused imidazole derivatives, their production and use
|
US5234917A
(en)
*
|
1989-12-29 |
1993-08-10 |
Finkelstein Joseph A |
Substituted 5-(alkyl)carboxamide imidazoles
|
JPH05503691A
(ja)
*
|
1989-12-29 |
1993-06-17 |
ユニバーシティ・テクノロジーズ・インターナショナル・インコーポレイテッド |
アゴニストおよびアンタゴニストを含む生物学的に活性なリガンドの3次構造モデルの設計方法およびアンギオテンシンに基づいた新規合成アンタゴニスト
|
US5449682A
(en)
*
|
1990-02-13 |
1995-09-12 |
Merck & Co., Inc. |
Angiotensin II antagonists incorporating a substituted benzyl element
|
ATE169915T1
(de)
*
|
1990-02-15 |
1998-09-15 |
Takeda Chemical Industries Ltd |
Pyrimidindionderivate, deren herstellung und verwendung
|
DE122007000050I1
(de)
*
|
1990-02-19 |
2007-11-08 |
Novartis Ag |
Acylverbindungen
|
MY106533A
(en)
*
|
1990-02-20 |
1995-06-30 |
Sumitomo Chemical Co |
A 4-tert.-butyl imidazole derivative and its production and use.
|
US5284661A
(en)
*
|
1990-02-22 |
1994-02-08 |
Takeda Chemical Industries, Ltd. |
Fused thiophene derivatives, their production and use
|
CA2037630C
(en)
*
|
1990-03-07 |
2001-07-03 |
Akira Morimoto |
Nitrogen-containing heterocylic compounds, their production and use
|
IE910913A1
(en)
*
|
1990-03-20 |
1991-09-25 |
Sanofi Sa |
N-substituted heterocyclic derivates, their preparation¹and pharmaceutical compositions containing them
|
FR2659967B1
(fr)
*
|
1990-03-20 |
1992-07-24 |
Sanofi Sa |
Derives d'imidazolinone n-substitues, leur preparation, les compositions pharmaceutiques en contenant.
|
FR2665702B1
(fr)
*
|
1990-08-08 |
1994-02-25 |
Sanofi |
Derives heterocycliques n-substitues, leur preparation, les compositions pharmaceutiques en contenant.
|
US5270317A
(en)
*
|
1990-03-20 |
1993-12-14 |
Elf Sanofi |
N-substituted heterocyclic derivatives, their preparation and the pharmaceutical compositions in which they are present
|
US5166206A
(en)
*
|
1990-03-30 |
1992-11-24 |
Merck & Co., Inc. |
Substituted pyrimidines, pyrimidinones and pyridopyrimidines
|
DE4010797A1
(de)
*
|
1990-04-04 |
1991-10-10 |
Hoechst Ag |
Substituierte azole, verfahren zu deren herstellung, diese enthaltende mittel und deren verwendung
|
US5196444A
(en)
*
|
1990-04-27 |
1993-03-23 |
Takeda Chemical Industries, Ltd. |
1-(cyclohexyloxycarbonyloxy)ethyl 2-ethoxy-1-[[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl]benzimidazole-7-carboxylate and compositions and methods of pharmaceutical use thereof
|
US5198439A
(en)
*
|
1990-04-19 |
1993-03-30 |
Imperial Chemical Industries Plc |
Angiotension II antagonizing pyridine derivatives
|
GB2244054B
(en)
*
|
1990-04-19 |
1994-04-06 |
Ici Plc |
Pyridine derivatives
|
ZA912983B
(en)
|
1990-04-27 |
1992-01-29 |
Takeda Chemical Industries Ltd |
Benzimidazole derivatives,their production and use
|
US5703110A
(en)
*
|
1990-04-27 |
1997-12-30 |
Takeda Chemical Industries, Ltd. |
Benzimidazole derivatives, their production and use
|
US6004989A
(en)
|
1990-04-27 |
1999-12-21 |
Takeda Chemical Industries, Ltd. |
Benzimidazole derivatives, their production and use
|
US5098920A
(en)
*
|
1990-05-04 |
1992-03-24 |
G. D. Searle & Co. |
1h-substituted-1,2,4-triazole compounds and methods of use thereof for treatment of cardiovascular disorders
|
US5821232A
(en)
*
|
1990-05-11 |
1998-10-13 |
Pfizer Inc. |
Synergistic therapeutic compositions and methods
|
DK0527879T3
(da)
|
1990-05-11 |
1997-07-14 |
Pfizer |
Synergistiske terapeutiske præparater og fremgangsmåder.
|
US5045540A
(en)
*
|
1990-05-25 |
1991-09-03 |
Warner-Lambert Co. |
Amino acid derivatives with angiotensin II antagonist properties
|
FR2663028B1
(fr)
*
|
1990-06-08 |
1994-10-14 |
Roussel Uclaf |
Nouveaux derives de benzimidazole, leur procede de preparation, les nouveaux intermediaires obtenus, leur application a titre de medicaments et les compositions pharmaceutiques les renfermant.
|
FR2674523A1
(fr)
*
|
1991-03-28 |
1992-10-02 |
Roussel Uclaf |
Nouveaux derives de benzimidazole, leur procede de preparation, les nouveaux intermediaires obtenus, leur application a titre de medicaments et les compositions pharmaceutiques les renfermant.
|
EP0461040A1
(fr)
|
1990-06-08 |
1991-12-11 |
Roussel Uclaf |
Dérivés de l'imidazole, leur procédé de préparation, les intermédiaires obtenus, leur application à titre de médicaments et les compositions pharmaceutiques les renfermant
|
ES2121773T3
(es)
*
|
1990-06-08 |
1998-12-16 |
Hoechst Marion Roussel Inc |
Derivados de bencimidazol, su procedimiento de preparacion, productos intermedios, su aplicacion como medicamentos y composiciones farmaceuticas que los contienen.
|
FR2670489B1
(fr)
*
|
1990-12-18 |
1994-10-14 |
Roussel Uclaf |
Nouveaux derives de benzimidazole, leur procede de preparation, les nouveaux intermediaires obtenus, leur application a titre de medicaments et les compositions pharmaceutiques les renfermant.
|
WO1991019715A1
(en)
*
|
1990-06-15 |
1991-12-26 |
G.D. Searle & Co. |
1H-SUBSTITUTED-IMIDAZO[4,5-d]PYRIDAZINE COMPOUNDS FOR TREATMENT OF CARDIOVASCULAR DISORDERS
|
NZ238688A
(en)
*
|
1990-06-28 |
1992-05-26 |
Smithkline Beecham Corp |
Substituted histidines: pharmaceutical compositions, preparation and uses thereof
|
CA2036148A1
(en)
*
|
1990-06-29 |
1991-12-30 |
Hiroki Tomioka |
A 1-phenylimidazole derivative and its production and use
|
FR2675503B1
(fr)
*
|
1991-04-19 |
1994-02-18 |
Roussel Uclaf |
Nouveaux derives soufres de l'imidazole, leur procede de preparation, les nouveaux intermediaires obtenus, leur application a titre de medicaments et les compositions pharmaceutiques les renfermant.
|
IL98319A
(en)
*
|
1990-07-05 |
1997-04-15 |
Roussel Uclaf |
Sulphurous derivatives of imidazole, their preparation process, and pharmaceutical compositions containing them
|
FR2664271B1
(fr)
*
|
1990-07-05 |
1994-02-18 |
Roussel Uclaf |
Nouveaux derives soufres de l'imidazole, leur procede de preparation, les nouveaux intermediaires obtenus, leur application a titre de medicaments et les compositions pharmaceutiques les renfermant.
|
CA2044806A1
(en)
*
|
1990-07-18 |
1992-01-19 |
Roland Jaunin |
Purine derivatives
|
DE4023215A1
(de)
*
|
1990-07-21 |
1992-01-23 |
Hoechst Ag |
Substituierte azole, verfahren zu deren herstellung, sie enthaltende mittel und deren verwendung
|
NZ239161A
(en)
*
|
1990-07-31 |
1994-01-26 |
Smithkline Beecham Corp |
Substituted [1h-imidazol-5-yl] alkanoic acid derivatives; medicaments,
|
GB9017482D0
(en)
*
|
1990-08-09 |
1990-09-26 |
Ici Plc |
Manufacturing process
|
GB9017480D0
(en)
*
|
1990-08-09 |
1990-09-26 |
Ici Plc |
Chemical process
|
AU8534291A
(en)
*
|
1990-08-10 |
1992-03-02 |
G.D. Searle & Co. |
Renal-selective angiotensin ii antagonists for treatment of hypertension
|
US5089626A
(en)
*
|
1990-08-23 |
1992-02-18 |
Merck & Co., Inc. |
Process for preparing an angiotensin II antagonist
|
US5217985A
(en)
*
|
1990-08-28 |
1993-06-08 |
G. D. Searle & Co. |
Renal-selective biphenylalkyl 1h-substituted-1,2,4-triazole angiotensin ii antagonists for treatment of hypertension
|
US5140036A
(en)
*
|
1990-09-19 |
1992-08-18 |
G. D. Searle & Co. |
1,3,5-trisubstituted-1,2,4-triazole compounds for treatment of circulatory disorders
|
US5229406A
(en)
*
|
1990-09-19 |
1993-07-20 |
G. D. Searle & Co. |
1,3,5-trisubstituted-1,2,4-triazole compounds for treatment of circulatory disorders
|
US5091390A
(en)
*
|
1990-09-20 |
1992-02-25 |
E. I. Du Pont De Nemours And Company |
Treatment of CNS disorders with 4,5,6,7-tetrahydro-1H-imidazo (4,5-)-pyridines and analogs
|
US5126342A
(en)
*
|
1990-10-01 |
1992-06-30 |
Merck & Co., Inc. |
Imidazole angiotensin ii antagonists incorporating acidic functional groups
|
EP0481614A1
(en)
*
|
1990-10-01 |
1992-04-22 |
Merck & Co. Inc. |
Substituted pyridopyrimidinones and related heterocycles as angiotensin II antagonists
|
AU9024591A
(en)
*
|
1990-10-25 |
1992-05-26 |
G.D. Searle & Co. |
Biphenylalkyl xanthine compounds for treatment of cardiovascular disorders
|
AU636066B2
(en)
*
|
1990-10-30 |
1993-04-08 |
Takeda Chemical Industries Ltd. |
Thienoimidazole derivatives, their production and use
|
US5238952A
(en)
*
|
1990-10-31 |
1993-08-24 |
G. D. Searle & Co. |
N-substituted imidazol-2-one compounds for treatment of circulatory disorders
|
US5087634A
(en)
*
|
1990-10-31 |
1992-02-11 |
G. D. Searle & Co. |
N-substituted imidazol-2-one compounds for treatment of circulatory disorders
|
GB9025123D0
(en)
*
|
1990-11-19 |
1991-01-02 |
Ici Plc |
Nitrogen compounds
|
AU9137791A
(en)
*
|
1990-12-14 |
1992-07-08 |
Smithkline Beecham Corporation |
Imidazolyl-alkenoic acids
|
US5175180A
(en)
*
|
1990-12-20 |
1992-12-29 |
G. D. Searle & Co. |
N-substituted n-(alpha-triazolyl-toluyl)pyrrole compounds and use for treatment of circulatory disorders
|
CA2058198A1
(en)
*
|
1991-01-04 |
1992-07-05 |
Adalbert Wagner |
Azole derivatives, process for their preparation, and their use
|
IE914572A1
(en)
*
|
1991-01-17 |
1992-07-29 |
Zeneca Ltd |
Chemical process
|
IE914573A1
(en)
*
|
1991-01-17 |
1992-07-29 |
Ici Plc |
Boron compounds
|
AT395853B
(de)
*
|
1991-01-31 |
1993-03-25 |
Chem Pharm Forsch Gmbh |
Neue imidazolderivate, verfahren zu ihrer herstellung und ihre verwendung
|
GB9102803D0
(en)
*
|
1991-02-11 |
1991-03-27 |
Ici Plc |
Pyridine compounds
|
IE920175A1
(en)
*
|
1991-02-11 |
1992-08-12 |
Zeneca Ltd |
Nitrogen heterocycles
|
US5472967A
(en)
*
|
1991-02-20 |
1995-12-05 |
Synthelabo |
4-pyrimidinone derivatives their preparation and their application in therapy
|
FR2672892B1
(fr)
*
|
1991-02-20 |
1994-01-14 |
Synthelabo |
Derives de 4-pyrimidinones, leur preparation et leur application en therapeutique.
|
US5616599A
(en)
*
|
1991-02-21 |
1997-04-01 |
Sankyo Company, Limited |
Angiotensin II antagosist 1-biphenylmethylimidazole compounds and their therapeutic use
|
CA2229000C
(en)
*
|
1991-02-21 |
2002-04-09 |
Sankyo Company, Limited |
1-biphenylimidazole derivatives, their preparation and their therapeutic use
|
US5187271A
(en)
*
|
1991-02-28 |
1993-02-16 |
G. D. Searle & Co. |
N-substituted (α-imidazolyl-toluyl) pyrrole compounds for treatment of circulatory disorders
|
US6008368A
(en)
*
|
1993-04-28 |
1999-12-28 |
G. D. Searle & Co. |
Pharmaceutical compositions for treatment of circulatory disorders using N-substituted (α-imidazolyl-toluyl) pyrrole aniotensin II antagonists
|
US5202328A
(en)
*
|
1991-03-06 |
1993-04-13 |
Merck & Co., Inc. |
Substituted fused pyrimidinones
|
EP0502575A1
(en)
*
|
1991-03-06 |
1992-09-09 |
Merck & Co. Inc. |
Substituted 1-(2H)-isoquinolinones
|
US5385894A
(en)
*
|
1991-03-06 |
1995-01-31 |
Merck & Co., Inc. |
Disubstituted 6-aminoquinazolinones
|
EP0505098A1
(en)
*
|
1991-03-19 |
1992-09-23 |
Merck & Co. Inc. |
Imidazole derivatives bearing acidic functional groups as angiotensin II antagonists
|
US5236928A
(en)
*
|
1991-03-19 |
1993-08-17 |
Merck & Co., Inc. |
Imidazole derivatives bearing acidic functional groups at the 5-position, their compositions and methods of use as angiotensin II antagonists
|
US5191086A
(en)
*
|
1991-03-19 |
1993-03-02 |
E.R. Squibb & Sons, Inc. |
Imidazole and benzimidazole derivatives
|
US5206235A
(en)
*
|
1991-03-20 |
1993-04-27 |
Merck & Co., Inc. |
Benzo-fused lactams that promote the release of growth hormone
|
US5196537A
(en)
*
|
1991-03-21 |
1993-03-23 |
G. D. Searle & Co. |
5-apylheteroarylalkyl-1,3,5-trisubstituted-1,2,4-triazole compounds for treatment of circulatory disorders
|
US5187179A
(en)
*
|
1991-03-22 |
1993-02-16 |
Merck & Co., Inc. |
Angiotensin II antagonists incorporating a substituted imidazo [1,2-b][1,2,4]triazole
|
US5128327A
(en)
*
|
1991-03-25 |
1992-07-07 |
Merck & Co., Inc. |
Angiotensin II antagonists incorporating a nitrogen containing six membered ring heterocycle
|
US5177074A
(en)
*
|
1991-03-26 |
1993-01-05 |
Merck & Co., Inc. |
Angiotensin ii antagonists incorporating a substituted thiophene or furan
|
US5164403A
(en)
*
|
1991-04-05 |
1992-11-17 |
G. D. Searle & Co. |
N-arylheteroarylalkyl imidazol-2-one compounds for treatment of circulatory disorders
|
US5155117A
(en)
*
|
1991-04-12 |
1992-10-13 |
G. D. Searle & Co. |
1-arylheteroarylalkyl substituted-1h-1,2,4-triazole compounds for treatment of circulatory disorders
|
TW274551B
(fi)
*
|
1991-04-16 |
1996-04-21 |
Takeda Pharm Industry Co Ltd |
|
US5190942A
(en)
*
|
1991-04-22 |
1993-03-02 |
E. R. Squibb & Sons, Inc. |
Benzoxazole and related heterocyclic substituted imidazole and benzimidazole derivatives
|
EP0511767A1
(en)
*
|
1991-04-29 |
1992-11-04 |
Merck & Co. Inc. |
Tablets containing compound DUP753
|
US5198438A
(en)
*
|
1991-05-07 |
1993-03-30 |
Merck & Co., Inc. |
Angiotensin ii antagonists incorporating a substituted thiophene or furan
|
US5506361A
(en)
*
|
1991-05-08 |
1996-04-09 |
Theupjohn Company |
Imidazobenzoquinones and composition for preventing or treating hypertension or congestive heart failure containing the same
|
US5223501A
(en)
*
|
1991-05-10 |
1993-06-29 |
Merck & Co., Inc. |
Substituted pyrimidinones bearing acidic functional groups as angiotensin ii antagonists
|
GB9110625D0
(en)
*
|
1991-05-16 |
1991-07-03 |
Glaxo Group Ltd |
Chemical compounds
|
GB9110636D0
(en)
*
|
1991-05-16 |
1991-07-03 |
Glaxo Group Ltd |
Chemical compounds
|
US5332820A
(en)
*
|
1991-05-20 |
1994-07-26 |
E. I. Du Pont De Nemours And Company |
Dibenzobicyclo(2.2.2) octane angiotensin II antagonists
|
US5175164A
(en)
*
|
1991-06-05 |
1992-12-29 |
Merck & Co., Inc. |
Angiotensin ii antagonists incorporating a substituted indole or dihydroindole
|
US5210211A
(en)
*
|
1991-06-21 |
1993-05-11 |
Warner-Lambert Company |
4-(1h-pyrrol-1-yl) imidazoles with angiotension ii antagonist activity
|
FR2677984B1
(fr)
*
|
1991-06-21 |
1994-02-25 |
Elf Sanofi |
Derives d'imidazoline n-substitues, leur preparation, les compositions pharmaceutiques en contenant.
|
IL102183A
(en)
*
|
1991-06-27 |
1999-11-30 |
Takeda Chemical Industries Ltd |
The heterocyclic compounds are converted into biphenyl groups, their production and the pharmaceutical compositions containing them
|
US5177097A
(en)
*
|
1991-07-24 |
1993-01-05 |
E. R. Squibb & Sons, Inc. |
Acyl amidine and acyl, guanidine substituted biphenyl derivatives
|
ES2098403T3
(es)
*
|
1991-09-10 |
1997-05-01 |
Tanabe Seiyaku Co |
Derivados de la imidazoindolizina y procedimiento para su preparacion.
|
IL103020A
(en)
*
|
1991-09-10 |
1998-10-30 |
Tanabe Seiyaku Co |
History of acid 3) 1, '1 in biphenyl 4 Methyl (4,5,6,7 tetrahydro H3 imidazo] C 4,5 [pyridine 4 carboxylic acid, preparation and pharmaceutical preparations containing them
|
ES2162792T3
(es)
*
|
1991-09-18 |
2002-01-16 |
Glaxo Group Ltd |
Derivados de benzanilida como antagonistas de 5-ht1d.
|
PT100905A
(pt)
*
|
1991-09-30 |
1994-02-28 |
Eisai Co Ltd |
Compostos heterociclicos azotados biciclicos contendo aneis de benzeno, ciclo-hexano ou piridina e de pirimidina, piridina ou imidazol substituidos e composicoes farmaceuticas que os contem
|
AT398202B
(de)
*
|
1991-10-04 |
1994-10-25 |
Chem Pharm Forsch Gmbh |
Neue imidazolderivate, verfahren zu ihrer herstellung und ihre verwendung
|
US5187159A
(en)
*
|
1991-10-07 |
1993-02-16 |
Merck & Co., Inc. |
Angiotensin II antagonists incorporating a substituted 1,3-benzodioxole or 1,3-benzodithiole
|
US5256654A
(en)
*
|
1991-10-24 |
1993-10-26 |
American Home Products Corporation |
Substituted pyrrolopyrimidines, azepinopyrimidines and pyridopyrimidines useful as angiotensin II antagonists
|
US5149699A
(en)
*
|
1991-10-24 |
1992-09-22 |
American Home Products Corporation |
Substituted pyridopyrimidines useful as antgiotensin II antagonists
|
US5484937A
(en)
*
|
1992-08-04 |
1996-01-16 |
G.D. Searle & Co. |
N-substituted N-(α-triazolyl-toluyl)pyrrole compounds for treatment of circulatory disorders
|
US5252753A
(en)
*
|
1991-11-01 |
1993-10-12 |
Ortho Pharmaceutical Corporation |
Process for the preparation of certain substituted biphenyl tetrazoles and compounds thereof
|
US5389661A
(en)
*
|
1991-12-05 |
1995-02-14 |
Warner-Lambert Company |
Imidazole and 1,2,4-triazole derivatives with angiotensin II antagonist properties
|
US5322950A
(en)
*
|
1991-12-05 |
1994-06-21 |
Warner-Lambert Company |
Imidazole with angiotensin II antagonist properties
|
US5350752A
(en)
*
|
1991-12-16 |
1994-09-27 |
E. R. Squibb & Sons, Inc. |
Dihydropyrimidine derivatives
|
US5212177A
(en)
*
|
1991-12-16 |
1993-05-18 |
E. R. Squibb & Sons, Inc. |
Indole and benzimidazole-substituted dihydropyrimidine derivatives
|
US5234923A
(en)
*
|
1991-12-16 |
1993-08-10 |
E. R. Squibb & Sons, Inc. |
Substitute indole and benzimidazole derivatives
|
US5308853A
(en)
*
|
1991-12-20 |
1994-05-03 |
Warner-Lambert Company |
Substituted-5-methylidene hydantoins with AT1 receptor antagonist properties
|
EP0550313A1
(fr)
*
|
1991-12-30 |
1993-07-07 |
Synthelabo |
Nouveaux dérivés de 2-(tétrazol-5-yl)-(1,1'-biphényle), leur préparation et leur utilisation comme intermédiaires de synthèse
|
FR2685697B1
(fr)
*
|
1991-12-30 |
1994-02-04 |
Synthelabo |
Nouveaux derives de 2-(tetrazol-5-yl)-(1,1'-biphenyle), leur preparation et leur utilisation comme intermediaires de synthese.
|
US5240953A
(en)
*
|
1992-01-30 |
1993-08-31 |
Ortho Pharmaceutical Corporation |
Substituted triazoles as angiotensin ii inhibitors
|
US5312958A
(en)
*
|
1992-01-31 |
1994-05-17 |
Takeda Chemical Industries, Ltd. |
Process for producing 4-bromomethylbiphenyl compounds
|
DE4206043A1
(de)
*
|
1992-02-27 |
1993-09-02 |
Bayer Ag |
Sulfonylbenzyl-substituierte imidazole
|
TW215434B
(fi)
*
|
1992-03-07 |
1993-11-01 |
Hoechst Ag |
|
US5208234A
(en)
*
|
1992-03-10 |
1993-05-04 |
E. R. Squibb & Sons, Inc. |
Substituted imidazole phosphonic and phosphinic acid derivatives
|
US5208235A
(en)
*
|
1992-03-10 |
1993-05-04 |
E. R. Squibb & Sons, Inc. |
Indole- and benzimidazole-substituted imidazole derivatives
|
FR2689508B1
(fr)
*
|
1992-04-01 |
1994-06-17 |
Fournier Ind & Sante |
Derives de l'imidazole, leur procede de preparation et leur application en therapeutique.
|
US5972990A
(en)
*
|
1992-04-10 |
1999-10-26 |
Brigham And Women's Hospital, Inc. |
Methods for reducing risk of repeat myocardial infarction and increasing survival in heart attack victims
|
US5378704A
(en)
*
|
1992-04-15 |
1995-01-03 |
E. R. Squibb & Sons, Inc. |
Non-peptidic angiotensin-II-receptor-antagonists
|
US5294722A
(en)
*
|
1992-04-16 |
1994-03-15 |
E. R. Squibb & Sons, Inc. |
Process for the preparation of imidazoles useful in angiotensin II antagonism
|
US5218125A
(en)
*
|
1992-04-23 |
1993-06-08 |
Merck & Co., Inc. |
Antihypertensive compound and method of use thereas
|
US5214153A
(en)
*
|
1992-04-23 |
1993-05-25 |
Merck & Co., Inc. |
Actinoplanes transformation process anti-hypertensive compound and method of use thereas
|
US5217882A
(en)
*
|
1992-05-18 |
1993-06-08 |
Merck & Co., Inc. |
Microbial transformation process for producing antihypertensive N2 -glucuronide products
|
PT573218E
(pt)
*
|
1992-06-02 |
2001-06-29 |
Sankyo Co |
4-carbonilimidazoles como antagonistas de angiotensina ii e sua utilizacao terapeutica
|
US5401851A
(en)
*
|
1992-06-03 |
1995-03-28 |
Eli Lilly And Company |
Angiotensin II antagonists
|
DE4221009A1
(de)
*
|
1992-06-26 |
1994-01-05 |
Bayer Ag |
Imidazolyl-substituierte Cyclohexanderivate
|
EP0577023A3
(en)
*
|
1992-07-01 |
1996-12-18 |
Hoechst Ag |
Angiotensin-ii receptor-antagonists for the treatment of arrhythmices
|
US5484955A
(en)
*
|
1992-07-06 |
1996-01-16 |
Takeda Chemical Industries, Ltd. |
Tri-higher alkyl tin azide and its use
|
GB9218449D0
(en)
|
1992-08-29 |
1992-10-14 |
Boots Co Plc |
Therapeutic agents
|
IT1255461B
(it)
*
|
1992-07-28 |
1995-11-02 |
Luso Farmaco Inst |
Eteri di imidazoli ad attivita' a ii antagonista
|
US5283241A
(en)
*
|
1992-08-28 |
1994-02-01 |
Merck & Co., Inc. |
Benzo-fused lactams promote release of growth hormone
|
US5583130A
(en)
*
|
1992-09-25 |
1996-12-10 |
Merck & Co., Inc. |
Benzo-fused lactams promote release of growth hormone
|
US5317017A
(en)
*
|
1992-09-30 |
1994-05-31 |
Merck & Co., Inc. |
N-biphenyl-3-amido substituted benzolactams stimulate growth hormone release
|
WO1994013666A1
(en)
*
|
1992-12-07 |
1994-06-23 |
Eisai Co., Ltd. |
Process for producing imidazopyridine derivative and intermediate
|
DE4242459A1
(de)
*
|
1992-12-16 |
1994-06-23 |
Merck Patent Gmbh |
Imidazopyridine
|
HU219598B
(hu)
*
|
1992-12-17 |
2001-05-28 |
Sankyo Co. Ltd. |
Bifenilvegyületek imidazol- és piridinszármazékai, eljárás előállításukra és ezeket a vegyületeket tartalmazó gyógyszerkészítmények
|
DE4302956A1
(de)
*
|
1993-02-03 |
1994-08-04 |
Bayer Ag |
Substituierte Imidazo(4,5-b)pyridine und Benzimidazole
|
US5284841A
(en)
*
|
1993-02-04 |
1994-02-08 |
Merck & Co., Inc. |
Benzo-fused lactams promote release of growth hormone
|
TW240224B
(fi)
*
|
1993-02-15 |
1995-02-11 |
Shikoku Kakoki Co Ltd |
|
EP0614890B1
(de)
*
|
1993-03-12 |
1997-09-03 |
Lonza AG |
Verfahren zur Herstellung von gegebenfalls 2-substituierten 5-Chlorimidazolen
|
DE4308788A1
(de)
*
|
1993-03-18 |
1994-09-22 |
Bayer Ag |
Hetero-tricyclisch-substituierte Phenyl-cyclohexan-carbonsäurederivate
|
US5721264A
(en)
*
|
1993-04-07 |
1998-02-24 |
Nissan Chemical Industries, Ltd. |
Pyrazole derivatives
|
US5451597A
(en)
*
|
1993-05-27 |
1995-09-19 |
G.D. Searle & Co. |
Treatment of circulatory disorders using n-substituted (α-imidazolyl-toluyl) pyrrole angiotensin II antagonists
|
LT3469B
(en)
|
1993-06-02 |
1995-10-25 |
Chem Pharm Forsch Gmbh |
Novel acylales of imidazol-5-carboxylic acid derivatives, process for their preparation and use thereof
|
US5508272A
(en)
|
1993-06-15 |
1996-04-16 |
Bristol-Myers Squibb Company |
Compounds containing a fused bicycle ring and processes therefor
|
HUT73813A
(en)
*
|
1993-06-30 |
1996-09-30 |
Wellcome Found |
Anti-athero-sclerotic diaryl compounds, process to prepare them and pharmaceutical compositions contg. them
|
US5610301A
(en)
*
|
1993-07-01 |
1997-03-11 |
American Cyanamid Company |
Process for the regioselective n-alkylation of quinazolinones
|
US5338740A
(en)
*
|
1993-07-13 |
1994-08-16 |
Pfizer Inc. |
Angiotensin II receptor antagonists
|
US5342944A
(en)
*
|
1993-07-19 |
1994-08-30 |
American Cyanamid Company |
Process for the preparation of 2-alkyl-3,5,6,7- or 8-substituted-4(3H)-quinazolinones
|
US5298517A
(en)
*
|
1993-10-07 |
1994-03-29 |
American Cyanamid Company |
Angiotensin II receptor blocking agents
|
US5438136A
(en)
*
|
1993-11-02 |
1995-08-01 |
Merck & Co., Inc. |
Benzo-fused macrocycles promote release of growth hormone
|
US5606054A
(en)
*
|
1993-12-14 |
1997-02-25 |
Merck & Co., Inc. |
Heterocyclic-fused lactams promote release of growth hormone
|
WO1995024902A1
(fr)
*
|
1994-03-16 |
1995-09-21 |
Sankyo Company, Limited |
Reducteur de tension oculaire
|
US5753672A
(en)
*
|
1994-04-19 |
1998-05-19 |
Tanabe Seiyaku Co., Ltd. |
Imidazopyridine derivatives and process for preparing the same
|
SE9502219D0
(sv)
*
|
1995-06-19 |
1995-06-19 |
Astra Ab |
Novel medical use
|
KR19990036324A
(ko)
*
|
1995-08-10 |
1999-05-25 |
고사이 아끼오 |
피리미딘-4-온 유도체, 제초제로서의 그의 용도, 그의 제조용중간체, 및 이들 화합물의 제조 방법
|
CA2232663C
(en)
*
|
1995-10-06 |
2008-04-08 |
Novartis Ag |
At1-receptor antagonists for preventing and treating postischemic renal failure and for protecting ischemic kidneys
|
AU1791497A
(en)
|
1996-02-29 |
1997-09-16 |
Novartis Ag |
At1 receptor antagonist for the stimulation of apoptosis
|
FR2753195B1
(fr)
|
1996-09-09 |
1998-11-27 |
Sanofi Sa |
Procede pour la preparation d'un cyanobiphenyle
|
JPH10203981A
(ja)
*
|
1997-01-21 |
1998-08-04 |
Kureha Chem Ind Co Ltd |
心疾患改善剤
|
TW418204B
(en)
*
|
1997-03-28 |
2001-01-11 |
Dev Center Biotechnology |
Novel 1,2,4-triazine-5-ketonyl benzene derivatives and the analogs, the preparation, and the pharmaceutical compositions as angiotension II receptor antogonists
|
BR9908474A
(pt)
|
1998-03-04 |
2000-12-05 |
Takeda Chemical Industries Ltd |
Preparação de liberação prolongada, processo para a produção de uma preparação de liberação prolongada, e, composição farmacêutica
|
DE19820064A1
(de)
*
|
1998-05-06 |
1999-11-11 |
Hoechst Marion Roussel De Gmbh |
Substituierte Sulfonylcyanamide, Verfahren zu ihrer Herstellung und ihre Verwendung als Medikament
|
ATE279396T1
(de)
|
1998-06-12 |
2004-10-15 |
Sod Conseils Rech Applic |
Imidazolderivate und ihre verwendung als somatostatin rezeptorliganden
|
DE19830431A1
(de)
|
1998-07-08 |
2000-01-13 |
Hoechst Marion Roussel De Gmbh |
Sulfonylamino-carbonsäure-N-arylamide als Guanylatcyclase-Aktivatoren
|
US6465502B1
(en)
|
1998-12-23 |
2002-10-15 |
Novartis Ag |
Additional therapeutic use
|
DE69935249T2
(de)
|
1998-12-23 |
2007-10-31 |
Novartis Ag |
Verwendung von at-1 rezeptorantagonisten oder at-2 rezeptormodulatoren zur behandlung von erkrankungen, die mit einer erhöhung an at-1 oder at-2 rezeptoren verbunden sind
|
CN101011390A
(zh)
|
1999-01-26 |
2007-08-08 |
诺瓦提斯公司 |
血管紧张素ⅱ受体拮抗剂在治疗急性心肌梗塞中的应用
|
SE9903028D0
(sv)
|
1999-08-27 |
1999-08-27 |
Astra Ab |
New use
|
US6849257B2
(en)
|
2000-02-04 |
2005-02-01 |
Children's Hospital Research Foundation |
Lipid hydrolysis therapy for atherosclerosis and related diseases
|
CA2417204A1
(en)
|
2000-08-01 |
2002-02-07 |
Societe De Conseils De Recherches Et D'applications Scientifiques (S.C.R |
Imidazolyl derivatives
|
AR033390A1
(es)
|
2000-08-22 |
2003-12-17 |
Novartis Ag |
Una composicion farmaceutica que comprende un antagonista del receptor at1 y un potenciador de la secrecion de insulina, el uso de dicha composicion para la fabricacion de un medicamento y un kit de partes
|
US8168616B1
(en)
|
2000-11-17 |
2012-05-01 |
Novartis Ag |
Combination comprising a renin inhibitor and an angiotensin receptor inhibitor for hypertension
|
BR0102252B1
(pt)
|
2001-04-10 |
2013-10-22 |
|
Sistema de liberação controlada para antagonista do receptor AT1 da angiotensina II, composição farmacêutica e seu uso
|
EP1444988A4
(en)
|
2001-11-13 |
2007-04-25 |
Takeda Pharmaceutical |
CANCER AGENT
|
DK1532269T3
(da)
|
2002-05-09 |
2012-03-12 |
Brigham & Womens Hospital |
1L1RL-1 som markør for kardiovaskulær sygdom
|
ES2299616T3
(es)
|
2002-06-12 |
2008-06-01 |
Sumitomo Chemical Company, Limited |
Procedimiento para producir 4'-bromometil-2-cianobifelino.
|
AU2003252259A1
(en)
*
|
2002-07-26 |
2004-02-16 |
Nihon Nohyaku Co., Ltd. |
Novel haloalkylsulfonanilide derivatives, herbicides and usage thereof
|
DE10335027A1
(de)
|
2003-07-31 |
2005-02-17 |
Boehringer Ingelheim Pharma Gmbh & Co. Kg |
Verwendung von Angiotensin II Rezeptor Antagonisten
|
DE10306179A1
(de)
|
2003-02-13 |
2004-08-26 |
Boehringer Ingelheim Pharma Gmbh & Co. Kg |
Verwendung von Dipyridamol in Kombination mit Acetylsalicylsäure und einem Angiotensin II-Antagonisten zur Schlaganfall-Prophylaxe
|
US7732162B2
(en)
|
2003-05-05 |
2010-06-08 |
Probiodrug Ag |
Inhibitors of glutaminyl cyclase for treating neurodegenerative diseases
|
GB0316546D0
(en)
|
2003-07-15 |
2003-08-20 |
Novartis Ag |
Process for the manufacture of organic compounds
|
JP2007504171A
(ja)
|
2003-08-29 |
2007-03-01 |
ザ ブライハム アンド ウイメンズ ホスピタル, インコーポレイテッド |
細胞壊死インヒビター
|
JP4537678B2
(ja)
*
|
2003-09-04 |
2010-09-01 |
住友化学株式会社 |
2’−(1h−テトラゾール−5−イル)ビフェニル−4−カルボアルデヒド結晶およびその製造方法
|
GB0327839D0
(en)
|
2003-12-01 |
2003-12-31 |
Novartis Ag |
Organic compounds
|
AU2004296829A1
(en)
|
2003-12-05 |
2005-06-23 |
The Cleveland Clinic Foundation |
Risk markers for cardiovascular disease
|
GB0402262D0
(en)
|
2004-02-02 |
2004-03-10 |
Novartis Ag |
Process for the manufacture of organic compounds
|
JP2007529459A
(ja)
|
2004-03-17 |
2007-10-25 |
ノバルティス アクチエンゲゼルシャフト |
治療に置けるレニン阻害剤の使用
|
ITTO20040264A1
(it)
|
2004-04-28 |
2004-07-28 |
Rotta Res Lab Spa |
Nuovi derivati pirrolici ad attivita' angiotensina-ii antagonista
|
WO2006038223A1
(en)
*
|
2004-10-06 |
2006-04-13 |
Matrix Laboratories Ltd |
A process for preparation of 2-n-butyl -4-chloro - 1 - {[2`- (2-triphenylmethyl - 2h - tetrazole - 5- yl) - 1, 1’ - biphenyl-4-yl] methyl}-lh- imidazoie-5-methanol (intermediate of losartan)
|
WO2006042192A2
(en)
|
2004-10-06 |
2006-04-20 |
The Brigham And Womens's Hospital, Inc. |
Relevance of achieved levels of markers of systemic inflammation following treatment
|
KR20130048281A
(ko)
|
2004-10-08 |
2013-05-09 |
노파르티스 아게 |
확장기 기능장애 또는 확장기 심부전의 예방 또는 치료를 위한 레닌 억제제의 용도
|
CN101039917A
(zh)
|
2004-10-15 |
2007-09-19 |
特瓦制药工业有限公司 |
制备替米沙坦的方法
|
RU2007115900A
(ru)
|
2004-10-27 |
2008-11-10 |
Дайити Санкио Компани, Лимитед (Jp) |
Производные бензола, имеющие 2 или более заместителей
|
DE502006004733D1
(de)
|
2005-02-03 |
2009-10-15 |
Ratiopharm Gmbh |
Verfahren zur herstellung von losartan
|
EP1890691A2
(en)
|
2005-05-31 |
2008-02-27 |
Mylan Laboratories, Inc |
Compositions comrising nebivolol
|
EP1752450A1
(en)
|
2005-08-01 |
2007-02-14 |
Merck Sante |
Imidazole derivatives as fructose-1,6-bisphosphatase inhibitors and pharmaceutical compositions containing them
|
WO2007026375A1
(en)
|
2005-08-31 |
2007-03-08 |
Suven Life Sciences |
Process for the preparation of losartan
|
US8119358B2
(en)
|
2005-10-11 |
2012-02-21 |
Tethys Bioscience, Inc. |
Diabetes-related biomarkers and methods of use thereof
|
CN101024643A
(zh)
*
|
2006-02-20 |
2007-08-29 |
上海艾力斯医药科技有限公司 |
咪唑-5-羧酸类衍生物、制备方法及其应用
|
US20080057590A1
(en)
|
2006-06-07 |
2008-03-06 |
Mickey Urdea |
Markers associated with arteriovascular events and methods of use thereof
|
CN101085772A
(zh)
*
|
2006-06-07 |
2007-12-12 |
上海艾力斯医药科技有限公司 |
一类具有PPARγ激动剂活性的化合物及其应用
|
EP1908469A1
(en)
|
2006-10-06 |
2008-04-09 |
Boehringer Ingelheim Vetmedica Gmbh |
Angiotensin II receptor antagonist for the treatment of systemic diseases in cats
|
ATE525371T1
(de)
|
2006-12-06 |
2011-10-15 |
Shanghai Allist Pharmaceutical Inc |
Salze von imidazol-5-carbonsäure-derivaten, herstellungsverfahren und verwendung davon
|
CN101214242A
(zh)
|
2007-01-05 |
2008-07-09 |
上海艾力斯医药科技有限公司 |
新的药用组合物
|
CA2679446C
(en)
|
2007-03-01 |
2016-05-17 |
Probiodrug Ag |
New use of glutaminyl cyclase inhibitors
|
DK2147315T3
(da)
|
2007-04-18 |
2013-09-23 |
Tethys Bioscience Inc |
Diabetesrelaterede biomarkører og fremgangsmåder til anvendelse deraf
|
EP2142514B1
(en)
|
2007-04-18 |
2014-12-24 |
Probiodrug AG |
Thiourea derivatives as glutaminyl cyclase inhibitors
|
CN101172953B
(zh)
*
|
2007-12-04 |
2011-12-28 |
王俊华 |
沙坦类治疗高血压药物替米沙坦中间体的制备方法
|
GB2462022B
(en)
|
2008-06-16 |
2011-05-25 |
Biovascular Inc |
Controlled release compositions of agents that reduce circulating levels of platelets and methods thereof
|
US8236843B2
(en)
*
|
2008-09-02 |
2012-08-07 |
Elder Pharmaceuticals Ltd. |
Anti inflammatory compounds
|
CA2772488C
(en)
|
2009-09-11 |
2018-04-17 |
Probiodrug Ag |
Heterocyclic derivatives as inhibitors of glutaminyl cyclase
|
US20110190807A1
(en)
|
2010-02-01 |
2011-08-04 |
The Hospital For Sick Children |
Remote ischemic conditioning for treatment and prevention of restenosis
|
ES2586231T3
(es)
|
2010-03-03 |
2016-10-13 |
Probiodrug Ag |
Inhibidores de glutaminil ciclasa
|
EP2545047B9
(en)
|
2010-03-10 |
2015-06-10 |
Probiodrug AG |
Heterocyclic inhibitors of glutaminyl cyclase (qc, ec 2.3.2.5)
|
KR20130040851A
(ko)
|
2010-03-31 |
2013-04-24 |
더 호스피탈 포 식 칠드런 |
심근 경색 후 결과를 개선시키기 위한 원격 허혈 처치의 사용
|
CN103354733B
(zh)
|
2010-04-08 |
2017-02-22 |
儿童医院 |
用于外伤性损伤的远端缺血处理的用途
|
US8541596B2
(en)
|
2010-04-21 |
2013-09-24 |
Probiodrug Ag |
Inhibitors
|
ES2570167T3
(es)
|
2011-03-16 |
2016-05-17 |
Probiodrug Ag |
Derivados de benzimidazol como inhibidores de glutaminil ciclasa
|
AU2011365756B2
(en)
|
2011-04-12 |
2015-07-30 |
Boryung Pharmaceutical Co., Ltd. |
Antihypertensive pharmaceutical composition
|
AU2012284039B2
(en)
|
2011-07-18 |
2017-03-30 |
Critical Care Diagnostics, Inc. |
Methods of treating cardiovascular diseases and predicting the efficacy of exercise therapy
|
CN103012377A
(zh)
*
|
2011-09-27 |
2013-04-03 |
江苏艾力斯生物医药有限公司 |
一种咪唑-5-羧酸酯的重结晶方法
|
US20130158080A1
(en)
|
2011-12-15 |
2013-06-20 |
Takeda Pharmaceuticals U.S.A., Inc. |
Methods for treating hypertension in black patients
|
KR20130074808A
(ko)
|
2011-12-16 |
2013-07-05 |
한올바이오파마주식회사 |
스타틴계 지질저하제에 의한 근육계 부작용의 치료 또는 예방을 위한 로사르탄을 포함하는 약제학적 조성물
|
RU2630677C2
(ru)
*
|
2011-12-21 |
2017-09-12 |
Оно Фармасьютикал Ко., Лтд. |
Соединения
|
KR102136431B1
(ko)
|
2012-05-11 |
2020-07-21 |
싱크로니시티 파마, 인크. |
크립토크롬 조절제로서의 카르바졸-함유 술폰아미드
|
EP2879666B1
(en)
|
2012-08-01 |
2020-04-08 |
Tavakoli, Zahra |
Free flowing, frozen compositions comprising a therapeutic agent
|
EP2968276A4
(en)
|
2013-03-15 |
2017-02-15 |
President and Fellows of Harvard College |
Hybrid necroptosis inhibitors
|
TWI690521B
(zh)
|
2014-04-07 |
2020-04-11 |
美商同步製藥公司 |
作為隱花色素調節劑之含有咔唑之醯胺類、胺基甲酸酯類及脲類
|
US10793520B2
(en)
|
2016-08-30 |
2020-10-06 |
Nippon Soda Co., Ltd. |
Sulfonylaminobenzamide compound and pest control agent
|
WO2019008077A1
(en)
|
2017-07-07 |
2019-01-10 |
Boehringer Ingelheim Vetmedica Gmbh |
ANTAGONIST OF THE ANGIOTENSIN II RECEPTOR FOR THE PREVENTION OR TREATMENT OF SYSTEMIC DISEASES IN CATS
|
EP3461819B1
(en)
|
2017-09-29 |
2020-05-27 |
Probiodrug AG |
Inhibitors of glutaminyl cyclase
|