BR112014014527A2 - combinações de azilsartan e clorotalidona para tratar hipertensão em pacientes negros - Google Patents

combinações de azilsartan e clorotalidona para tratar hipertensão em pacientes negros

Info

Publication number
BR112014014527A2
BR112014014527A2 BR112014014527A BR112014014527A BR112014014527A2 BR 112014014527 A2 BR112014014527 A2 BR 112014014527A2 BR 112014014527 A BR112014014527 A BR 112014014527A BR 112014014527 A BR112014014527 A BR 112014014527A BR 112014014527 A2 BR112014014527 A2 BR 112014014527A2
Authority
BR
Brazil
Prior art keywords
chlorotalidone
azilsartan
combinations
treat hypertension
black patients
Prior art date
Application number
BR112014014527A
Other languages
English (en)
Inventor
Kupfer Stuart
Original Assignee
Takeda Pharmaceuticals Usa Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Pharmaceuticals Usa Inc filed Critical Takeda Pharmaceuticals Usa Inc
Publication of BR112014014527A2 publication Critical patent/BR112014014527A2/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4245—Oxadiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/4035—Isoindoles, e.g. phthalimide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Abstract

resumo combinações de azilsartan e clorotalidona para tratar hipertensão em pacientes negros a presente invenção refere-se a métodos de tratamento da hipertensão em um paciente negro usando uma quantidade terapeuticamente eficaz de uma combinação de um bloqueador de receptor da angiotensina ii e clorotalidona.
BR112014014527A 2011-12-15 2012-12-10 combinações de azilsartan e clorotalidona para tratar hipertensão em pacientes negros BR112014014527A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161570965P 2011-12-15 2011-12-15
PCT/US2012/068768 WO2013090196A1 (en) 2011-12-15 2012-12-10 Combinations of azilsartan and chlorthalidone for treating hypertension black patients

Publications (1)

Publication Number Publication Date
BR112014014527A2 true BR112014014527A2 (pt) 2017-06-13

Family

ID=47430119

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112014014527A BR112014014527A2 (pt) 2011-12-15 2012-12-10 combinações de azilsartan e clorotalidona para tratar hipertensão em pacientes negros

Country Status (7)

Country Link
US (1) US20130158080A1 (pt)
AP (1) AP2014007766A0 (pt)
BR (1) BR112014014527A2 (pt)
MA (1) MA35866B1 (pt)
TN (1) TN2014000259A1 (pt)
TW (1) TW201330848A (pt)
WO (1) WO2013090196A1 (pt)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106389428B (zh) * 2016-10-11 2019-12-13 上海现代制药股份有限公司 一种具有提高阿齐沙坦生物利用度和稳定性的组合物及制备方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1334092C (en) 1986-07-11 1995-01-24 David John Carini Angiotensin ii receptor blocking imidazoles
ATE190051T1 (de) 1989-06-14 2000-03-15 Smithkline Beecham Corp Imidazoalkensäure
DE19675036I2 (de) 1990-02-19 2004-10-21 Novartis Ag Acylverbindungen.
TW201738B (pt) 1990-03-20 1993-03-11 Sanofi Co
US5196444A (en) 1990-04-27 1993-03-23 Takeda Chemical Industries, Ltd. 1-(cyclohexyloxycarbonyloxy)ethyl 2-ethoxy-1-[[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl]benzimidazole-7-carboxylate and compositions and methods of pharmaceutical use thereof
IE920540A1 (en) 1991-02-21 1992-08-26 Sankyo Co 1-biphenylmethylimidazole derivatives, their preparation and¹their therapetuic use
DE4121975A1 (de) 1991-07-03 1993-01-07 Basf Ag Thermoplastische formmassen auf der basis von polycarbonaten, styrol/acrylnitril-polymerisaten und polyolefinen
TW226375B (pt) 1991-10-24 1994-07-11 American Home Prod
US7157584B2 (en) 2004-02-25 2007-01-02 Takeda Pharmaceutical Company Limited Benzimidazole derivative and use thereof
WO2010075347A2 (en) * 2008-12-23 2010-07-01 Takeda Pharmaceutical Company Limited Methods of treating hypertension with at least one angiotensin ii receptor blocker and chlorthalidone

Also Published As

Publication number Publication date
WO2013090196A1 (en) 2013-06-20
AP2014007766A0 (en) 2014-07-31
US20130158080A1 (en) 2013-06-20
MA35866B1 (fr) 2014-12-01
TN2014000259A1 (en) 2015-09-30
TW201330848A (zh) 2013-08-01

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Legal Events

Date Code Title Description
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]

Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI

B06T Formal requirements before examination [chapter 6.20 patent gazette]
B11E Dismissal acc. art. 34 of ipl - requirements for examination incomplete
B11E Dismissal acc. art. 34 of ipl - requirements for examination incomplete
B11T Dismissal of application maintained [chapter 11.20 patent gazette]
B350 Update of information on the portal [chapter 15.35 patent gazette]