FI940031A - Nya 2-cyan-3-hyroxipropenamidderivat, förfarande för deras användning som läkemedel och farmaceutiska kompositioner som innehåller dessa - Google Patents

Nya 2-cyan-3-hyroxipropenamidderivat, förfarande för deras användning som läkemedel och farmaceutiska kompositioner som innehåller dessa Download PDF

Info

Publication number
FI940031A
FI940031A FI940031A FI940031A FI940031A FI 940031 A FI940031 A FI 940031A FI 940031 A FI940031 A FI 940031A FI 940031 A FI940031 A FI 940031A FI 940031 A FI940031 A FI 940031A
Authority
FI
Finland
Prior art keywords
hydroxypropenamide
cyan
pharmaceuticals
derivatives
new
Prior art date
Application number
FI940031A
Other languages
English (en)
Finnish (fi)
Other versions
FI106553B (sv
FI940031A0 (sv
Inventor
Elizabeth Anne Kuo
Original Assignee
Roussel Uclaf
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf filed Critical Roussel Uclaf
Publication of FI940031A0 publication Critical patent/FI940031A0/sv
Publication of FI940031A publication Critical patent/FI940031A/sv
Application granted granted Critical
Publication of FI106553B publication Critical patent/FI106553B/sv

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72Nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72Nitrogen atoms
    • C07D213/75Amino or imino radicals, acylated by carboxylic or carbonic acids, or by sulfur or nitrogen analogues thereof, e.g. carbamates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pyridine Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
FI940031A 1993-01-05 1994-01-04 Förfarande för framställning av nya, terapeutiskt användbara 2-cyan-3-hydroxipropenamidderivat FI106553B (sv)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB9300083 1993-01-05
GB939300083A GB9300083D0 (en) 1993-01-05 1993-01-05 Chemical compounds

Publications (3)

Publication Number Publication Date
FI940031A0 FI940031A0 (sv) 1994-01-04
FI940031A true FI940031A (sv) 1994-07-06
FI106553B FI106553B (sv) 2001-02-28

Family

ID=10728304

Family Applications (1)

Application Number Title Priority Date Filing Date
FI940031A FI106553B (sv) 1993-01-05 1994-01-04 Förfarande för framställning av nya, terapeutiskt användbara 2-cyan-3-hydroxipropenamidderivat

Country Status (33)

Country Link
US (1) US5346912A (sv)
EP (1) EP0606175B1 (sv)
JP (1) JP3334988B2 (sv)
KR (1) KR100295717B1 (sv)
CN (1) CN1042935C (sv)
AT (1) ATE128968T1 (sv)
AU (1) AU663017B2 (sv)
BR (1) BR9400017A (sv)
CA (1) CA2112866C (sv)
CZ (1) CZ283948B6 (sv)
DE (1) DE69400024T2 (sv)
DK (1) DK0606175T3 (sv)
EE (1) EE03001B1 (sv)
ES (1) ES2078130T3 (sv)
FI (1) FI106553B (sv)
GB (1) GB9300083D0 (sv)
GR (1) GR3017723T3 (sv)
HR (1) HRP940006B1 (sv)
HU (1) HU216835B (sv)
IL (1) IL107788A (sv)
LT (1) LT3766B (sv)
LV (1) LV10712B (sv)
MX (1) MX9400274A (sv)
NO (1) NO300839B1 (sv)
NZ (1) NZ250520A (sv)
PL (1) PL175135B1 (sv)
RU (1) RU2126387C1 (sv)
SI (1) SI9300686A (sv)
SK (1) SK280508B6 (sv)
TW (1) TW259785B (sv)
UA (1) UA40573C2 (sv)
YU (1) YU49047B (sv)
ZA (1) ZA939118B (sv)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2338804A1 (en) * 1998-07-28 2000-02-10 Smithkline Beecham Corporation Propenamides as ccr5 modulators
WO2006115509A2 (en) 2004-06-24 2006-11-02 Novartis Vaccines And Diagnostics Inc. Small molecule immunopotentiators and assays for their detection
MX2010001462A (es) 2007-08-27 2010-03-01 Basf Se Compuestos de pirazol para controlar plagas de invertebrados.
US8729083B2 (en) 2008-09-24 2014-05-20 Basf Se Pyrazole compounds for controlling invertebrate pests
US9029639B2 (en) 2009-07-06 2015-05-12 Basf Se Pyridazine compounds for controlling invertebrate pests
EP2451808B1 (en) 2009-07-06 2014-03-26 Basf Se Pyridazine compounds for controlling invertebrate pests
EP2456308A2 (en) 2009-07-24 2012-05-30 Basf Se Pyridine derivatives for controlling invertrebate pests
KR20160079123A (ko) 2013-11-22 2016-07-05 젠자임 코포레이션 신경변성 질병을 치료하기 위한 신규한 방법
CN105693574B (zh) * 2014-11-25 2017-12-19 中国科学院大连化学物理研究所 2‑烷硫基烯酰胺衍生物及其合成方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL186239B (nl) 1975-06-05 Hoechst Ag Werkwijze voor de bereiding van een geneesmiddel met antiflogistische en/of analgetische werking, alsmede werkwijze voor de bereiding van een 2-hydroxyethylideencyaanazijnzuuranilide geschikt voor toepassing bij deze werkwijze.
DE2555789A1 (de) * 1975-12-11 1977-07-07 Hoechst Ag Neue cyanessigsaeureanilid-derivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende mittel
US4435407A (en) * 1982-01-07 1984-03-06 Ciba-Geigy Corporation Certain substituted β-oxo-α-carbamoylpyrrolepropionitriles
DE3534440A1 (de) 1985-09-27 1987-04-02 Hoechst Ag Arzneimittel gegen chronische graft-versus-host-krankheiten sowie gegen autoimmunerkrankungen, insbesondere systemischen lupus erythematodes
US4888357A (en) 1988-01-26 1989-12-19 Bristol-Myers Company Antiarthritic β-cycloalkyl-β-oxopropionitriles
IL92508A0 (en) * 1988-12-08 1990-08-31 Ciba Geigy Ag Novel alpha-cyano-beta-oxopropionamides
AU649421B2 (en) * 1990-05-18 1994-05-26 Sanofi-Aventis Deutschland Gmbh Isoxazole-4-carboxamides and hydroxyalkylidene-cyanoacetamides, drugs containing these compounds and use of such drugs
IL99811A (en) * 1990-10-30 1996-03-31 Roussel Uclaf 3-Cycloalkyl-propanamides, tautomeric forms of these, their salts, method of preparation, use as drugs and preparations containing them
IL102790A (en) * 1991-09-17 1996-01-31 Roussel Uclaf History of 3-cycloalkyl-prop-2-anamide

Also Published As

Publication number Publication date
TW259785B (en) 1995-10-11
EP0606175B1 (fr) 1995-10-11
RU94000064A (ru) 1996-07-10
PL175135B1 (pl) 1998-11-30
CN1097005A (zh) 1995-01-04
HRP940006A2 (en) 1996-10-31
HU9400033D0 (en) 1994-05-30
CA2112866C (fr) 2007-03-13
DK0606175T3 (da) 1996-02-19
ATE128968T1 (de) 1995-10-15
PL301774A1 (en) 1994-07-11
DE69400024D1 (de) 1995-11-16
LT3766B (en) 1996-03-25
GR3017723T3 (en) 1996-01-31
YU82593A (sh) 1996-07-24
CZ292193A3 (en) 1994-07-13
HU216835B (hu) 1999-09-28
IL107788A (en) 1998-08-16
EE03001B1 (et) 1997-06-16
SK280508B6 (sk) 2000-03-13
SI9300686A (en) 1994-09-30
FI106553B (sv) 2001-02-28
EP0606175A1 (fr) 1994-07-13
NO940020L (sv) 1994-07-06
HRP940006B1 (en) 1999-12-31
CA2112866A1 (fr) 1994-07-06
HUT71471A (en) 1995-11-28
UA40573C2 (uk) 2001-08-15
NO300839B1 (no) 1997-08-04
YU49047B (sh) 2003-07-07
KR100295717B1 (ko) 2001-11-05
NZ250520A (en) 1996-08-27
ZA939118B (en) 1995-01-18
CZ283948B6 (cs) 1998-07-15
JP3334988B2 (ja) 2002-10-15
GB9300083D0 (en) 1993-03-03
DE69400024T2 (de) 1996-04-04
ES2078130T3 (es) 1995-12-01
MX9400274A (es) 1994-08-31
NO940020D0 (no) 1994-01-04
RU2126387C1 (ru) 1999-02-20
LTIP1634A (en) 1995-02-27
IL107788A0 (en) 1994-02-27
CN1042935C (zh) 1999-04-14
US5346912A (en) 1994-09-13
AU663017B2 (en) 1995-09-21
LV10712B (en) 1995-12-20
KR940018363A (ko) 1994-08-16
AU5213093A (en) 1994-07-14
SK149593A3 (en) 1994-12-07
JPH06211793A (ja) 1994-08-02
LV10712A (lv) 1995-06-20
FI940031A0 (sv) 1994-01-04
BR9400017A (pt) 1994-08-02

Similar Documents

Publication Publication Date Title
MX22406A (es) Nuevos derivados de n-aril y n-heteroarilamidas y urea como inhibidores de acil coenzima a: acil transferasa del colesterol (acat).
DK0778277T3 (da) Substituerede heterocycliske derivater som CRF antagonister
ITMI921203A1 (it) Derivati di s-triazina come agenti fotostabilizzanti
ES2079534T3 (es) Derivados de polietilenglicol, sus peptidos modificados, metodos para producirlos y uso de los peptidos modificados.
FI940031A0 (sv) Nya 2-cyan-3-hyroxipropenamidderivat, förfarande för deras användning som läkemedel och farmaceutiska kompositioner som innehåller dessa
FI960689A (sv) Substituerade bensensulfonylureor och -tioureor, förfarande för deras framställning, deras användning som läkemedel eller som diagnosticum samt läkemedel som innehåller dem
PT873993E (pt) Novos compostos heterociclicos processo para a sua preparacao e as composicoes farmaceuticas que os contem
ATE265451T1 (de) 2-aminoidan derivate, verfahren zu deren herstellung und diese enthaltende pharmazeutische zusammenstellungen
DE69113893D1 (de) 6,7-Disubstituierte 2-Aminotetraline als Immunomodulatoren und pharmazeutische Zusammensetzungen davon.
FI844552L (fi) Aralkyl(aryletynyl)aralkyl-aminer och deras anvaendning som blodkaerlsutvidgande och blodtryckssaenkande medel.
ES2143159T3 (es) Nuevos derivados de 2-ciano-3-hidroxi-propenamidas que comprenden un radical trifluorometilsulfonilfenilo/trifluorometilsulfinilfenilo, procedimiento de preparacion, aplicacion como medicamentos y composiciones farmaceuticas que los contienen.
ATE299489T1 (de) Aminderivate und verfahren zu ihrer herstellung
DE69106235D1 (de) N-Oxyimidsäurederivate.

Legal Events

Date Code Title Description
MA Patent expired