FI93421B - Befruktning förhindrande implantat - Google Patents

Befruktning förhindrande implantat Download PDF

Info

Publication number
FI93421B
FI93421B FI883594A FI883594A FI93421B FI 93421 B FI93421 B FI 93421B FI 883594 A FI883594 A FI 883594A FI 883594 A FI883594 A FI 883594A FI 93421 B FI93421 B FI 93421B
Authority
FI
Finland
Prior art keywords
implant
vinyl acetate
release
ethylene
weight
Prior art date
Application number
FI883594A
Other languages
English (en)
Finnish (fi)
Other versions
FI883594A (sv
FI93421C (sv
FI883594A0 (sv
Inventor
Nijs Hendrik De
Original Assignee
Akzo Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=19850428&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=FI93421(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Akzo Nv filed Critical Akzo Nv
Publication of FI883594A0 publication Critical patent/FI883594A0/sv
Publication of FI883594A publication Critical patent/FI883594A/sv
Publication of FI93421B publication Critical patent/FI93421B/sv
Application granted granted Critical
Publication of FI93421C publication Critical patent/FI93421C/sv

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0092—Hollow drug-filled fibres, tubes of the core-shell type, coated fibres, coated rods, microtubules or nanotubes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Dermatology (AREA)
  • Nanotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Orthopedics, Nursing, And Contraception (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Materials For Medical Uses (AREA)
  • Non-Silver Salt Photosensitive Materials And Non-Silver Salt Photography (AREA)
  • Prostheses (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Compositions Of Macromolecular Compounds (AREA)

Claims (5)

1. Implantat med kontraceptiv aktivitet, vilket används för subkutan eller local utlösning, k ä n n e - 5 tecknat därav, att det omfattar a) ett kärnmaterial som bestär av en etylen/vinylacetatsampolymer, vilken har en sädan molekylvikt, att smältindexet är större än 10 g/10 min och vinylacetathal-ten är 20 vikt-% eller större, och kärnmaterialet tjänst- 10 gör som matris för 3-keto-desogestrel, levonorgestrel eller gestoden, vilka är aktiva, kontraceptiva medel, i en mängd som är tillräcklig för längvarig konstant frigörelse av ätminstone ca 15 - 30 pg av det aktiva medlet per dag och 15 b) ett membran, vilket har en skikttjocklek av 50 - 250 pm och omger kärnmaterialet och ocksä bestär av ett etylen/vinylacetatmedel, men har en sädan molekylvikt, att smältindexet är mindre än 10 g/10 min och vinylacetathal-ten är mindre än 20 vikt-%, 20 vilket implantat är helt eller praktiskt taget helt cylin-derformat och dess största yttre diameter är ca 2 mm och längd under ca 5 cm.
2. Implantat enligt patentkrav 1, känne-tecknat därav, att det framställs genom koaxialt 25 sprutning av tvä etylen/vinylacetatsampolymer.
3. Implantat enligt patentkrav 1 eller 2, k ä n -netecknat därav, att som kärnmaterial används en etylen/vinylacetatsampolymer, vars smältindex är 25 - 30 g/10 min och vinylacetathalt är större än 25 vikt-%. 30
4. Implantat enligt patentkrav 1 eller 2, k ä n - netecknat därav, att som membranmaterial används ett etylen/vinylacetatmaterial, vars smältindex är mindre eller lika stor än 8 g/10 min och vinylacetathalt är mindre än 20 vikt-%. 35
5. Implantat enligt patentkrav 1 eller 2, k ä n - netecknat därav, att som kontraceptivt aktivt medel används 3-keto-desogestrel.
FI883594A 1987-08-08 1988-08-01 Befruktning förhindrande implantat FI93421C (sv)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
NL8701868 1987-08-08
NL8701868 1987-08-08

Publications (4)

Publication Number Publication Date
FI883594A0 FI883594A0 (sv) 1988-08-01
FI883594A FI883594A (sv) 1989-02-09
FI93421B true FI93421B (sv) 1994-12-30
FI93421C FI93421C (sv) 1995-04-10

Family

ID=19850428

Family Applications (1)

Application Number Title Priority Date Filing Date
FI883594A FI93421C (sv) 1987-08-08 1988-08-01 Befruktning förhindrande implantat

Country Status (19)

Country Link
US (3) US4957119A (sv)
EP (1) EP0303306B1 (sv)
JP (1) JP2571831B2 (sv)
KR (1) KR950008763B1 (sv)
CN (1) CN1024753C (sv)
AT (1) ATE86484T1 (sv)
AU (1) AU603475B2 (sv)
CA (1) CA1309949C (sv)
DE (2) DE3879031T2 (sv)
DK (1) DK173166B1 (sv)
ES (1) ES2054784T3 (sv)
FI (1) FI93421C (sv)
HK (1) HK1002020A1 (sv)
IE (1) IE61730B1 (sv)
MX (1) MX9203817A (sv)
NL (1) NL980027I2 (sv)
NZ (1) NZ225399A (sv)
PT (1) PT88220B (sv)
ZA (1) ZA885034B (sv)

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Also Published As

Publication number Publication date
ATE86484T1 (de) 1993-03-15
FI883594A (sv) 1989-02-09
IE61730B1 (en) 1994-11-30
US5088505A (en) 1992-02-18
DE3879031D1 (de) 1993-04-15
AU2044988A (en) 1989-03-02
MX9203817A (es) 1992-08-01
DK438688A (da) 1989-02-09
US5150718A (en) 1992-09-29
NL980027I1 (nl) 1998-12-01
KR950008763B1 (en) 1995-08-08
CN1031323A (zh) 1989-03-01
JPS6470410A (en) 1989-03-15
US4957119A (en) 1990-09-18
DE3879031T2 (de) 1993-06-24
FI93421C (sv) 1995-04-10
NZ225399A (en) 1990-09-26
CA1309949C (en) 1992-11-10
EP0303306B1 (en) 1993-03-10
KR890003360A (ko) 1989-04-14
AU603475B2 (en) 1990-11-15
NL980027I2 (nl) 1999-02-01
DK173166B1 (da) 2000-02-28
PT88220B (pt) 1995-03-01
DK438688D0 (da) 1988-08-05
EP0303306A1 (en) 1989-02-15
CN1024753C (zh) 1994-06-01
ES2054784T3 (es) 1994-08-16
FI883594A0 (sv) 1988-08-01
ZA885034B (en) 1989-03-29
PT88220A (pt) 1989-06-30
DE19975054I2 (de) 2000-04-13
HK1002020A1 (en) 1998-07-24
IE882118L (en) 1989-02-08
JP2571831B2 (ja) 1997-01-16

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