FI93421B - Befruktning förhindrande implantat - Google Patents
Befruktning förhindrande implantat Download PDFInfo
- Publication number
- FI93421B FI93421B FI883594A FI883594A FI93421B FI 93421 B FI93421 B FI 93421B FI 883594 A FI883594 A FI 883594A FI 883594 A FI883594 A FI 883594A FI 93421 B FI93421 B FI 93421B
- Authority
- FI
- Finland
- Prior art keywords
- implant
- vinyl acetate
- release
- ethylene
- weight
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0092—Hollow drug-filled fibres, tubes of the core-shell type, coated fibres, coated rods, microtubules or nanotubes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Dermatology (AREA)
- Nanotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Orthopedics, Nursing, And Contraception (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Materials For Medical Uses (AREA)
- Non-Silver Salt Photosensitive Materials And Non-Silver Salt Photography (AREA)
- Prostheses (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines Containing Plant Substances (AREA)
- Compositions Of Macromolecular Compounds (AREA)
Claims (5)
1. Implantat med kontraceptiv aktivitet, vilket används för subkutan eller local utlösning, k ä n n e - 5 tecknat därav, att det omfattar a) ett kärnmaterial som bestär av en etylen/vinylacetatsampolymer, vilken har en sädan molekylvikt, att smältindexet är större än 10 g/10 min och vinylacetathal-ten är 20 vikt-% eller större, och kärnmaterialet tjänst- 10 gör som matris för 3-keto-desogestrel, levonorgestrel eller gestoden, vilka är aktiva, kontraceptiva medel, i en mängd som är tillräcklig för längvarig konstant frigörelse av ätminstone ca 15 - 30 pg av det aktiva medlet per dag och 15 b) ett membran, vilket har en skikttjocklek av 50 - 250 pm och omger kärnmaterialet och ocksä bestär av ett etylen/vinylacetatmedel, men har en sädan molekylvikt, att smältindexet är mindre än 10 g/10 min och vinylacetathal-ten är mindre än 20 vikt-%, 20 vilket implantat är helt eller praktiskt taget helt cylin-derformat och dess största yttre diameter är ca 2 mm och längd under ca 5 cm.
2. Implantat enligt patentkrav 1, känne-tecknat därav, att det framställs genom koaxialt 25 sprutning av tvä etylen/vinylacetatsampolymer.
3. Implantat enligt patentkrav 1 eller 2, k ä n -netecknat därav, att som kärnmaterial används en etylen/vinylacetatsampolymer, vars smältindex är 25 - 30 g/10 min och vinylacetathalt är större än 25 vikt-%. 30
4. Implantat enligt patentkrav 1 eller 2, k ä n - netecknat därav, att som membranmaterial används ett etylen/vinylacetatmaterial, vars smältindex är mindre eller lika stor än 8 g/10 min och vinylacetathalt är mindre än 20 vikt-%. 35
5. Implantat enligt patentkrav 1 eller 2, k ä n - netecknat därav, att som kontraceptivt aktivt medel används 3-keto-desogestrel.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
NL8701868 | 1987-08-08 | ||
NL8701868 | 1987-08-08 |
Publications (4)
Publication Number | Publication Date |
---|---|
FI883594A0 FI883594A0 (sv) | 1988-08-01 |
FI883594A FI883594A (sv) | 1989-02-09 |
FI93421B true FI93421B (sv) | 1994-12-30 |
FI93421C FI93421C (sv) | 1995-04-10 |
Family
ID=19850428
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FI883594A FI93421C (sv) | 1987-08-08 | 1988-08-01 | Befruktning förhindrande implantat |
Country Status (19)
Country | Link |
---|---|
US (3) | US4957119A (sv) |
EP (1) | EP0303306B1 (sv) |
JP (1) | JP2571831B2 (sv) |
KR (1) | KR950008763B1 (sv) |
CN (1) | CN1024753C (sv) |
AT (1) | ATE86484T1 (sv) |
AU (1) | AU603475B2 (sv) |
CA (1) | CA1309949C (sv) |
DE (2) | DE3879031T2 (sv) |
DK (1) | DK173166B1 (sv) |
ES (1) | ES2054784T3 (sv) |
FI (1) | FI93421C (sv) |
HK (1) | HK1002020A1 (sv) |
IE (1) | IE61730B1 (sv) |
MX (1) | MX9203817A (sv) |
NL (1) | NL980027I2 (sv) |
NZ (1) | NZ225399A (sv) |
PT (1) | PT88220B (sv) |
ZA (1) | ZA885034B (sv) |
Families Citing this family (95)
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US5114719A (en) * | 1987-04-29 | 1992-05-19 | Sabel Bernhard A | Extended drug delivery of small, water-soluble molecules |
US5156164A (en) * | 1988-10-13 | 1992-10-20 | Leveen Harry H | Iodine contraceptive sponge |
BE1002600A3 (fr) * | 1988-11-23 | 1991-04-09 | Wildemeersch Dirk | Dispositif intra-uterin perfectionne. |
IE71202B1 (en) * | 1990-12-17 | 1997-02-12 | Akzo Nv | Progestagen-only contraceptive |
WO1993017662A1 (en) * | 1992-03-02 | 1993-09-16 | Daratech Pty. Ltd. | Improved implants |
EP0572932B1 (en) * | 1992-06-02 | 2000-09-13 | C.R. Bard, Inc. | Method and implant device for long term delivery of drugs |
US5368588A (en) * | 1993-02-26 | 1994-11-29 | Bettinger; David S. | Parenteral fluid medication reservoir pump |
US5443461A (en) * | 1993-08-31 | 1995-08-22 | Alza Corporation | Segmented device for simultaneous delivery of multiple beneficial agents |
US5681817A (en) | 1994-02-04 | 1997-10-28 | The Medical College Of Hampton Roads | Treatment of ovarian estrogen dependent conditions |
US5660848A (en) * | 1994-11-02 | 1997-08-26 | The Population Council, Center For Biomedical Research | Subdermally implantable device |
US5521166A (en) * | 1994-12-19 | 1996-05-28 | Ortho Pharmaceitical Corporation | Antiprogestin cyclophasic hormonal regimen |
DE19539361A1 (de) * | 1995-10-23 | 1997-04-24 | Basf Ag | Verfahren zur Herstellung von mehrschichtigen, festen Arzneiformen zur oralen oder rektalen Verabreichung |
US5733565A (en) * | 1996-02-23 | 1998-03-31 | The Population Council, Center For Biomedical Research | Male contraceptive implant |
CN1088993C (zh) * | 1996-10-11 | 2002-08-14 | 上海市计划生育科学研究所 | 含孕二烯酮的长效皮下避孕埋植剂 |
US6203813B1 (en) | 1997-01-13 | 2001-03-20 | Lance L. Gooberman | Pharmaceutical delivery device and method of preparation therefor |
TW358031B (en) * | 1997-04-11 | 1999-05-11 | Akze Nobel N V | Drug delivery system for 2 or more active substances |
DE19744135C1 (de) * | 1997-09-29 | 1999-03-25 | Schering Ag | Beschichtete medizinische Implantate, Verfahren zu ihrer Herstellung und ihre Verwendung zur Restenoseprophylaxe |
ATE313422T1 (de) | 1998-05-01 | 2006-01-15 | Duramed Pharmaceuticals Inc | Verfahren zur spritzgussherstellung von vorrichtungen mit kontrollierter wirkstofffreisetzung und damit hergestellte vorrichtung |
US6117441A (en) * | 1998-07-02 | 2000-09-12 | The Population Council, Inc. | Silicone core long term androgen delivery implant |
JP2002520346A (ja) * | 1998-07-17 | 2002-07-09 | ファルマシア・アンド・アップジョン・カンパニー | 避妊用皮下メドロキシプロゲステロンアセタート |
US6117442A (en) * | 1998-11-12 | 2000-09-12 | Leiras Oy | Drug delivery device, especially for the delivery of androgens |
US6063395A (en) * | 1998-11-12 | 2000-05-16 | Leiras Oy | Drug delivery device especially for the delivery of progestins and estrogens |
US6217895B1 (en) | 1999-03-22 | 2001-04-17 | Control Delivery Systems | Method for treating and/or preventing retinal diseases with sustained release corticosteroids |
CA2267743C (en) * | 1999-03-30 | 2011-07-26 | Robert F. Casper | Low dose estrogen interrupted hormone replacement therapy |
US6375972B1 (en) * | 2000-04-26 | 2002-04-23 | Control Delivery Systems, Inc. | Sustained release drug delivery devices, methods of use, and methods of manufacturing thereof |
CA2415349A1 (en) * | 2000-08-23 | 2002-02-28 | Akzo Nobel N.V. | Testosterone ester formulation for human use |
AU2003267309A1 (en) | 2000-11-16 | 2004-04-08 | Microspherix Llc | Flexible and/or elastic brachytherapy seed or strand |
AU2002305079B8 (en) * | 2001-05-11 | 2006-05-25 | Ortho-Mcneil Pharmaceutical, Inc. | Immune modulation device for use in animals |
CN1261099C (zh) | 2001-07-02 | 2006-06-28 | 阿克佐诺贝尔公司 | 四氢喹啉衍生物 |
AU2002313517B2 (en) * | 2001-08-31 | 2007-09-06 | Bayer Schering Pharma Oy | Drug delivery system |
TWI228508B (en) | 2001-09-04 | 2005-03-01 | Akzo Nobel Nv | Thieno[2,3-d]pyrimidines with combined LH and FSH agonistic activity |
HUP0401443A3 (en) | 2001-09-04 | 2008-05-28 | Organon Nv | Glycine-substituted thieno[2,3-d]pyrimidines with lh and fsh agonistic activity, use of the compounds and pharmaceutical compositions containing same |
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EP1539184B1 (en) * | 2002-08-28 | 2006-11-22 | Robert Casper | Estrogen replacement regimen |
KR20050072812A (ko) | 2002-11-07 | 2005-07-12 | 악조 노벨 엔.브이. | 안드로겐-수용체와 관련된 질병의 치료에 효과적인 인돌 |
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US20050031667A1 (en) | 2003-03-31 | 2005-02-10 | Patel Rajesh A. | Implantable polymeric device for sustained release of dopamine agonist |
DE602004026173D1 (de) | 2003-04-29 | 2010-05-06 | Gen Hospital Corp | Verfahren und vorrichtungen für die verzögerte freisetzung von mehreren arzneimitteln |
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LT2462246T (lt) | 2009-09-28 | 2017-11-27 | Intarcia Therapeutics, Inc | Esminio stacionaraus vaisto tiekimo greitas įgyvendinimas ir (arba) nutraukimas |
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US10028858B2 (en) | 2011-07-11 | 2018-07-24 | Medicines360 | Intrauterine systems, IUD insertion devices, and related methods and kits therefor |
AR089765A1 (es) * | 2012-01-23 | 2014-09-17 | Bayer Oy | Un sistema para el suministro de un farmaco |
AU2014214537B2 (en) | 2013-02-06 | 2019-01-03 | Mark SILLENDER | Therapeutic substance transfer catheter and method |
US10188426B2 (en) | 2013-02-06 | 2019-01-29 | Mark SILLENDER | Embryo transfer catheter and method |
US10413504B2 (en) | 2013-12-11 | 2019-09-17 | Merck Sharp & Dohme Corp. | Intravaginal ring drug delivery system |
WO2015086489A1 (en) | 2013-12-11 | 2015-06-18 | Merck Sharp & Dohme B.V. | Drug delivery system for delivery of anti-virals |
US9889085B1 (en) | 2014-09-30 | 2018-02-13 | Intarcia Therapeutics, Inc. | Therapeutic methods for the treatment of diabetes and related conditions for patients with high baseline HbA1c |
WO2016149561A1 (en) * | 2015-03-17 | 2016-09-22 | Oak Crest Institute Of Science | Subdermal implants for the sustained delivery of water-soluble drugs |
US10925639B2 (en) | 2015-06-03 | 2021-02-23 | Intarcia Therapeutics, Inc. | Implant placement and removal systems |
EP3733694A1 (en) | 2016-05-16 | 2020-11-04 | Intarcia Therapeutics, Inc | Glucagon-receptor selective polypeptides and methods of use thereof |
USD860451S1 (en) | 2016-06-02 | 2019-09-17 | Intarcia Therapeutics, Inc. | Implant removal tool |
USD840030S1 (en) | 2016-06-02 | 2019-02-05 | Intarcia Therapeutics, Inc. | Implant placement guide |
EP3518896A4 (en) * | 2016-09-29 | 2020-08-05 | Gesea Biosciences Inc. | BIOERODABLE IMPLANT FOR LONG-TERM DRUG DELIVERY AND RELATED MANUFACTURING AND USE PROCEDURES |
CN110225762A (zh) | 2017-01-03 | 2019-09-10 | 因塔西亚制药公司 | 包括glp-1受体激动剂的连续施用和药物的共同施用的方法 |
US11571328B2 (en) | 2018-04-09 | 2023-02-07 | Medicines360 | IUD insertion devices |
US11690807B2 (en) | 2018-05-24 | 2023-07-04 | Celanese Eva Performance Polymers Llc | Implantable device for sustained release of a macromolecular drug compound |
EP3801378A4 (en) * | 2018-05-24 | 2022-02-23 | Celanese EVA Performance Polymers LLC | IMPLANTABLE DEVICE FOR THE DELAYED RELEASE OF A MACROMOLECULAR DRUG COMPOUND |
US20200261258A1 (en) | 2019-02-19 | 2020-08-20 | Medicines360 | Devices, systems, methods and kits for insertion and removal of iuds |
BR102020007749A2 (pt) | 2020-04-17 | 2021-11-03 | Edson Luiz Peracchi | Implante subcutâneo reabsorvível de longa duração com liberação controlada de substância farmacologicamente ativa pré-concentrada em polímero para tratamento da endometriose |
BR102020010923A2 (pt) | 2020-05-29 | 2021-12-14 | Luiz Peracchi Edson | Implante subcutâneo reabsorvível de longa duração com liberação prolongada de substância farmacologicamente ativa pré-concentrada em polímero para tratamento da insuficiência adrenal crônica ou hipocortisolismo |
BR102020013862A2 (pt) | 2020-07-07 | 2022-01-18 | Edson Luiz Peracchi | Implante subcutâneo reabsorvível de longa duração com liberação sustentada de substância farmacologicamente ativa pré-concentrada em polímero para tratamento da doença de parkinson |
US20240165064A1 (en) | 2021-03-29 | 2024-05-23 | Edson Luiz Peracchi | Long-lasting resorbable subcutaneous implant with prolonged release of pre-concentrated pharmacologically active substance in polymer for the treatment of hypothyroidism, and method |
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GB202401392D0 (en) | 2024-02-02 | 2024-03-20 | Imphatec Ltd | Implant for delivery of a drug |
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-
1988
- 1988-07-07 AT AT88201432T patent/ATE86484T1/de not_active IP Right Cessation
- 1988-07-07 ES ES88201432T patent/ES2054784T3/es not_active Expired - Lifetime
- 1988-07-07 EP EP88201432A patent/EP0303306B1/en not_active Expired - Lifetime
- 1988-07-07 DE DE8888201432T patent/DE3879031T2/de not_active Expired - Lifetime
- 1988-07-07 DE DE1999175054 patent/DE19975054I2/de active Active
- 1988-07-11 IE IE211888A patent/IE61730B1/en not_active IP Right Cessation
- 1988-07-12 ZA ZA885034A patent/ZA885034B/xx unknown
- 1988-07-13 NZ NZ225399A patent/NZ225399A/xx unknown
- 1988-07-25 CA CA000572897A patent/CA1309949C/en not_active Expired - Lifetime
- 1988-08-01 FI FI883594A patent/FI93421C/sv not_active IP Right Cessation
- 1988-08-04 AU AU20449/88A patent/AU603475B2/en not_active Expired
- 1988-08-05 DK DK198804386A patent/DK173166B1/da active Protection Beyond IP Right Term
- 1988-08-05 US US07/229,066 patent/US4957119A/en not_active Expired - Lifetime
- 1988-08-06 KR KR88010063A patent/KR950008763B1/ko not_active IP Right Cessation
- 1988-08-06 CN CN88104894A patent/CN1024753C/zh not_active Expired - Lifetime
- 1988-08-08 JP JP63197812A patent/JP2571831B2/ja not_active Expired - Lifetime
- 1988-08-08 PT PT88220A patent/PT88220B/pt not_active IP Right Cessation
-
1990
- 1990-06-21 US US07/541,559 patent/US5088505A/en not_active Expired - Lifetime
-
1992
- 1992-02-14 US US07/836,632 patent/US5150718A/en not_active Expired - Lifetime
- 1992-06-29 MX MX9203817A patent/MX9203817A/es unknown
-
1998
- 1998-02-11 HK HK98101032A patent/HK1002020A1/xx not_active IP Right Cessation
- 1998-09-30 NL NL980027C patent/NL980027I2/nl unknown
Also Published As
Publication number | Publication date |
---|---|
ATE86484T1 (de) | 1993-03-15 |
FI883594A (sv) | 1989-02-09 |
IE61730B1 (en) | 1994-11-30 |
US5088505A (en) | 1992-02-18 |
DE3879031D1 (de) | 1993-04-15 |
AU2044988A (en) | 1989-03-02 |
MX9203817A (es) | 1992-08-01 |
DK438688A (da) | 1989-02-09 |
US5150718A (en) | 1992-09-29 |
NL980027I1 (nl) | 1998-12-01 |
KR950008763B1 (en) | 1995-08-08 |
CN1031323A (zh) | 1989-03-01 |
JPS6470410A (en) | 1989-03-15 |
US4957119A (en) | 1990-09-18 |
DE3879031T2 (de) | 1993-06-24 |
FI93421C (sv) | 1995-04-10 |
NZ225399A (en) | 1990-09-26 |
CA1309949C (en) | 1992-11-10 |
EP0303306B1 (en) | 1993-03-10 |
KR890003360A (ko) | 1989-04-14 |
AU603475B2 (en) | 1990-11-15 |
NL980027I2 (nl) | 1999-02-01 |
DK173166B1 (da) | 2000-02-28 |
PT88220B (pt) | 1995-03-01 |
DK438688D0 (da) | 1988-08-05 |
EP0303306A1 (en) | 1989-02-15 |
CN1024753C (zh) | 1994-06-01 |
ES2054784T3 (es) | 1994-08-16 |
FI883594A0 (sv) | 1988-08-01 |
ZA885034B (en) | 1989-03-29 |
PT88220A (pt) | 1989-06-30 |
DE19975054I2 (de) | 2000-04-13 |
HK1002020A1 (en) | 1998-07-24 |
IE882118L (en) | 1989-02-08 |
JP2571831B2 (ja) | 1997-01-16 |
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