FI930270A - Cefalosporiner och homologer, framstaellningsfoerfaranden samt farmaceutiska kompositioner - Google Patents
Cefalosporiner och homologer, framstaellningsfoerfaranden samt farmaceutiska kompositioner Download PDFInfo
- Publication number
- FI930270A FI930270A FI930270A FI930270A FI930270A FI 930270 A FI930270 A FI 930270A FI 930270 A FI930270 A FI 930270A FI 930270 A FI930270 A FI 930270A FI 930270 A FI930270 A FI 930270A
- Authority
- FI
- Finland
- Prior art keywords
- framstaellningsfoerfaranden
- cefalosporiner
- homologer
- samt
- composer
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
- C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
- C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D463/00—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D463/10—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
- C07D463/14—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hetero atoms directly attached in position 7
- C07D463/16—Nitrogen atoms
- C07D463/18—Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof
- C07D463/20—Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof with the acylating radicals further substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D463/22—Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof with the acylating radicals further substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen further substituted by nitrogen atoms
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Cephalosporin Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB909016189A GB9016189D0 (en) | 1990-07-24 | 1990-07-24 | Novel compounds |
| GB919109540A GB9109540D0 (en) | 1991-05-02 | 1991-05-02 | Novel compounds |
| PCT/GB1991/001228 WO1992001696A1 (en) | 1990-07-24 | 1991-07-22 | Cephalosporins and homologues, preparations and pharmaceutical compositions |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FI930270A0 FI930270A0 (fi) | 1993-01-22 |
| FI930270A true FI930270A (fi) | 1993-03-22 |
Family
ID=26297372
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI930270A FI930270A (fi) | 1990-07-24 | 1993-01-22 | Cefalosporiner och homologer, framstaellningsfoerfaranden samt farmaceutiska kompositioner |
Country Status (26)
| Country | Link |
|---|---|
| EP (2) | EP0540609B1 (fi) |
| JP (2) | JPH05509089A (fi) |
| KR (1) | KR100189075B1 (fi) |
| CN (2) | CN1061046C (fi) |
| AP (1) | AP832A (fi) |
| AT (1) | ATE185567T1 (fi) |
| AU (1) | AU648329B2 (fi) |
| CA (2) | CA2087967C (fi) |
| CZ (1) | CZ6493A3 (fi) |
| DE (2) | DE69131714T2 (fi) |
| DK (1) | DK0540609T3 (fi) |
| ES (1) | ES2137162T3 (fi) |
| FI (1) | FI930270A (fi) |
| GR (1) | GR3031711T3 (fi) |
| HU (1) | HUT63628A (fi) |
| IE (1) | IE912569A1 (fi) |
| IL (1) | IL98909A0 (fi) |
| LU (1) | LU91290I2 (fi) |
| MX (1) | MX9100317A (fi) |
| MY (1) | MY106399A (fi) |
| NL (1) | NL300249I2 (fi) |
| NO (1) | NO930226L (fi) |
| NZ (1) | NZ239061A (fi) |
| PT (1) | PT98426A (fi) |
| WO (2) | WO1992001696A1 (fi) |
| YU (1) | YU129691A (fi) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9125645D0 (en) * | 1991-12-03 | 1992-01-29 | Smithkline Beecham Plc | Novel compounds |
| DE69331047T2 (de) * | 1992-01-22 | 2002-03-21 | Pfizer Inc., New York | 2-isocephem und -oxacephemderivate,verfahren zu deren herstellung, deren zwischenprodukte und verwendung als antibakterielle mittel |
| GB9212609D0 (en) * | 1992-06-13 | 1992-07-29 | Smithkline Beecham Plc | Novel compounds |
| GB9213567D0 (en) * | 1992-06-26 | 1992-08-12 | Smithkline Beecham Plc | Novel compounds |
| GB9424847D0 (en) * | 1994-12-09 | 1995-02-08 | Smithkline Beecham Plc | Novel process |
| GB2300856A (en) * | 1995-05-16 | 1996-11-20 | Pfizer Ltd | Beta-lactam preparation |
| AU4398297A (en) * | 1996-10-02 | 1998-04-24 | Daiichi Pharmaceutical Co., Ltd. | Method for esterifying carboxylic compounds |
| FR2776292B1 (fr) | 1998-03-20 | 2004-09-10 | Oncopharm | Cephalotaxanes porteurs de chaine laterale et leur procede de synthese |
| GB0019124D0 (en) | 2000-08-03 | 2000-09-27 | Pfizer | Novel process |
| JP2004515503A (ja) * | 2000-12-04 | 2004-05-27 | ファイザー・プロダクツ・インク | セファロスポリン系抗生物質の製造のために有用な方法及びエステル誘導体 |
| PL362144A1 (en) * | 2000-12-04 | 2004-10-18 | Pfizer Products Inc. | Coupling process and intermediates useful for preparing cephalosphorins |
| US7378408B2 (en) * | 2001-11-30 | 2008-05-27 | Pfizer Inc. | Methods of treatment and formulations of cephalosporin |
| KR100710555B1 (ko) | 2001-12-04 | 2007-04-24 | 에스케이 주식회사 | 광학적으로 순수한 (ｒ)-폼 또는 (ｓ)-폼의테트라히드로퓨라닐 케톤의 제조방법 |
| SG11201402826YA (en) | 2011-12-22 | 2014-12-30 | Alios Biopharma Inc | Substituted nucleosides, nucleotides and analogs thereof |
| USRE48171E1 (en) | 2012-03-21 | 2020-08-25 | Janssen Biopharma, Inc. | Substituted nucleosides, nucleotides and analogs thereof |
| US9441007B2 (en) | 2012-03-21 | 2016-09-13 | Alios Biopharma, Inc. | Substituted nucleosides, nucleotides and analogs thereof |
| EA027929B1 (ru) | 2012-05-25 | 2017-09-29 | Янссен Сайенсиз Айрлэнд Юси | Нуклеозиды на основе урацила и спирооксетана |
| SG11201504554UA (en) | 2012-12-21 | 2015-07-30 | Alios Biopharma Inc | Substituted nucleosides, nucleotides and analogs thereof |
| CN105254648B (zh) * | 2015-11-13 | 2018-04-03 | 广东温氏大华农生物科技有限公司 | 一种头孢维星及其钠盐的合成方法 |
| GB2575261B (en) | 2018-07-02 | 2022-03-09 | Norbrook Lab Ltd | Intermediates in the synthesis of C3-substituted cephalosporins |
| CN112638944A (zh) | 2018-08-23 | 2021-04-09 | 西进公司 | 抗tigit抗体 |
| TW202128675A (zh) | 2019-12-06 | 2021-08-01 | 美商維泰克斯製藥公司 | 作為鈉通道調節劑之經取代四氫呋喃 |
| JP7429799B2 (ja) | 2020-02-18 | 2024-02-08 | ギリアード サイエンシーズ， インコーポレイテッド | 抗ウイルス化合物 |
| TWI775313B (zh) | 2020-02-18 | 2022-08-21 | 美商基利科學股份有限公司 | 抗病毒化合物 |
| TW202322824A (zh) | 2020-02-18 | 2023-06-16 | 美商基利科學股份有限公司 | 抗病毒化合物 |
| CN111620893B (zh) * | 2020-06-08 | 2021-12-14 | 重庆医药高等专科学校 | C-3位四氢呋喃取代的头孢菌素-铁载体耦合物及其制备方法和应用 |
| EP4323362A1 (en) | 2021-04-16 | 2024-02-21 | Gilead Sciences, Inc. | Methods of preparing carbanucleosides using amides |
| PE20241335A1 (es) | 2021-06-04 | 2024-07-03 | Vertex Pharma | N-(hidroxialquil (hetero)aril) tetrahidrofurano carboxamidas como moduladores de canales de sodio |
| US12116380B2 (en) | 2021-08-18 | 2024-10-15 | Gilead Sciences, Inc. | Phospholipid compounds and methods of making and using the same |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE793448A (fr) * | 1971-12-31 | 1973-06-28 | Roussel Uclaf | Procede de preparation de nouveaux derives des cephalosporines et produits obtenus |
| FR2197573A1 (en) * | 1972-09-07 | 1974-03-29 | Roussel Uclaf | 7-substd-phenylacetamido-cephalosporin derivs - - antibiotics active against streptococci and staphylococci |
| BE791160A (fr) * | 1972-01-03 | 1973-05-09 | Beecham Group Ltd | Nouveaux cephemes substitues |
| BE791161A (fr) * | 1972-01-03 | 1973-05-09 | Beecham Group Ltd | Procede pour la preparation d'analogues des cephalosporines |
| NL7305936A (fi) * | 1972-05-05 | 1973-11-07 | ||
| JPS5849382A (ja) * | 1981-09-18 | 1983-03-23 | Kyowa Hakko Kogyo Co Ltd | β−ラクタム化合物 |
| GB8821797D0 (en) * | 1988-09-16 | 1988-10-19 | Beecham Group Plc | Novel compounds |
| ES2121745T3 (es) * | 1989-03-30 | 1998-12-16 | Pfizer | Cefalosporinas y sus homologos, procedimiento para su preparacion y composiciones farmaceuticas. |
-
1991
- 1991-07-16 MY MYPI91001321A patent/MY106399A/en unknown
- 1991-07-22 ES ES91913583T patent/ES2137162T3/es not_active Expired - Lifetime
- 1991-07-22 AP APAP/P/1991/000305A patent/AP832A/en active
- 1991-07-22 AT AT91913583T patent/ATE185567T1/de active
- 1991-07-22 EP EP91913583A patent/EP0540609B1/en not_active Expired - Lifetime
- 1991-07-22 IL IL98909A patent/IL98909A0/xx unknown
- 1991-07-22 EP EP91913545A patent/EP0540606A1/en not_active Withdrawn
- 1991-07-22 CZ CS9364A patent/CZ6493A3/cs unknown
- 1991-07-22 AU AU82224/91A patent/AU648329B2/en not_active Expired
- 1991-07-22 CA CA002087967A patent/CA2087967C/en not_active Expired - Lifetime
- 1991-07-22 WO PCT/GB1991/001228 patent/WO1992001696A1/en active IP Right Grant
- 1991-07-22 CA CA002359744A patent/CA2359744C/en not_active Expired - Lifetime
- 1991-07-22 JP JP3512255A patent/JPH05509089A/ja active Pending
- 1991-07-22 JP JP3512368A patent/JP2851428B2/ja not_active Expired - Lifetime
- 1991-07-22 WO PCT/GB1991/001227 patent/WO1992001695A1/en not_active Application Discontinuation
- 1991-07-22 NZ NZ239061A patent/NZ239061A/en not_active IP Right Cessation
- 1991-07-22 HU HU93177A patent/HUT63628A/hu unknown
- 1991-07-22 KR KR1019930700216A patent/KR100189075B1/ko not_active IP Right Cessation
- 1991-07-22 MX MX9100317A patent/MX9100317A/es unknown
- 1991-07-22 DK DK91913583T patent/DK0540609T3/da active
- 1991-07-22 IE IE256991A patent/IE912569A1/en not_active IP Right Cessation
- 1991-07-22 DE DE69131714T patent/DE69131714T2/de not_active Expired - Lifetime
- 1991-07-22 DE DE200612000065 patent/DE122006000065I2/de active Active
- 1991-07-23 PT PT98426A patent/PT98426A/pt not_active Application Discontinuation
- 1991-07-23 YU YU129691A patent/YU129691A/sh unknown
- 1991-07-24 CN CN91105783A patent/CN1061046C/zh not_active Expired - Lifetime
-
1993
- 1993-01-22 FI FI930270A patent/FI930270A/fi unknown
- 1993-01-22 NO NO93930226A patent/NO930226L/no unknown
-
1998
- 1998-11-14 CN CN98122407A patent/CN1111410C/zh not_active Expired - Lifetime
-
1999
- 1999-11-03 GR GR990402803T patent/GR3031711T3/el unknown
-
2006
- 2006-11-22 LU LU91290C patent/LU91290I2/fr unknown
- 2006-11-27 NL NL300249C patent/NL300249I2/en unknown
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