FI930270A - Cefalosporiner och homologer, framstaellningsfoerfaranden samt farmaceutiska kompositioner - Google Patents
Cefalosporiner och homologer, framstaellningsfoerfaranden samt farmaceutiska kompositioner Download PDFInfo
- Publication number
- FI930270A FI930270A FI930270A FI930270A FI930270A FI 930270 A FI930270 A FI 930270A FI 930270 A FI930270 A FI 930270A FI 930270 A FI930270 A FI 930270A FI 930270 A FI930270 A FI 930270A
- Authority
- FI
- Finland
- Prior art keywords
- framstaellningsfoerfaranden
- cefalosporiner
- homologer
- samt
- composer
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
- C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
- C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D463/00—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D463/10—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
- C07D463/14—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hetero atoms directly attached in position 7
- C07D463/16—Nitrogen atoms
- C07D463/18—Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof
- C07D463/20—Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof with the acylating radicals further substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D463/22—Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof with the acylating radicals further substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen further substituted by nitrogen atoms
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Cephalosporin Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB909016189A GB9016189D0 (en) | 1990-07-24 | 1990-07-24 | Novel compounds |
| GB919109540A GB9109540D0 (en) | 1991-05-02 | 1991-05-02 | Novel compounds |
| PCT/GB1991/001228 WO1992001696A1 (en) | 1990-07-24 | 1991-07-22 | Cephalosporins and homologues, preparations and pharmaceutical compositions |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FI930270A0 FI930270A0 (fi) | 1993-01-22 |
| FI930270A true FI930270A (fi) | 1993-03-22 |
Family
ID=26297372
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI930270A FI930270A (fi) | 1990-07-24 | 1993-01-22 | Cefalosporiner och homologer, framstaellningsfoerfaranden samt farmaceutiska kompositioner |
Country Status (26)
| Country | Link |
|---|---|
| EP (2) | EP0540609B1 (fi) |
| JP (2) | JPH05509089A (fi) |
| KR (1) | KR100189075B1 (fi) |
| CN (2) | CN1061046C (fi) |
| AP (1) | AP832A (fi) |
| AT (1) | ATE185567T1 (fi) |
| AU (1) | AU648329B2 (fi) |
| CA (2) | CA2087967C (fi) |
| CZ (1) | CZ6493A3 (fi) |
| DE (2) | DE69131714T2 (fi) |
| DK (1) | DK0540609T3 (fi) |
| ES (1) | ES2137162T3 (fi) |
| FI (1) | FI930270A (fi) |
| GR (1) | GR3031711T3 (fi) |
| HU (1) | HUT63628A (fi) |
| IE (1) | IE912569A1 (fi) |
| IL (1) | IL98909A0 (fi) |
| LU (1) | LU91290I2 (fi) |
| MX (1) | MX9100317A (fi) |
| MY (1) | MY106399A (fi) |
| NL (1) | NL300249I2 (fi) |
| NO (1) | NO930226L (fi) |
| NZ (1) | NZ239061A (fi) |
| PT (1) | PT98426A (fi) |
| WO (2) | WO1992001695A1 (fi) |
| YU (1) | YU129691A (fi) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9125645D0 (en) * | 1991-12-03 | 1992-01-29 | Smithkline Beecham Plc | Novel compounds |
| JPH07503460A (ja) * | 1992-01-22 | 1995-04-13 | ファイザー・インコーポレイテッド | ２−イソセフェムおよびオキサセファム誘導体，それらの製法，その中間体および抗菌剤としての使用 |
| GB9212609D0 (en) * | 1992-06-13 | 1992-07-29 | Smithkline Beecham Plc | Novel compounds |
| GB9213567D0 (en) * | 1992-06-26 | 1992-08-12 | Smithkline Beecham Plc | Novel compounds |
| GB9424847D0 (en) * | 1994-12-09 | 1995-02-08 | Smithkline Beecham Plc | Novel process |
| GB2300856A (en) * | 1995-05-16 | 1996-11-20 | Pfizer Ltd | Beta-lactam preparation |
| WO1998014421A1 (fr) * | 1996-10-02 | 1998-04-09 | Daiichi Pharmaceutical Co., Ltd. | Procede d'esterification de composes carboxyliques |
| FR2776292B1 (fr) | 1998-03-20 | 2004-09-10 | Oncopharm | Cephalotaxanes porteurs de chaine laterale et leur procede de synthese |
| GB0019124D0 (en) * | 2000-08-03 | 2000-09-27 | Pfizer | Novel process |
| HUP0400642A3 (en) * | 2000-12-04 | 2010-03-29 | Pfizer Prod Inc | Coupling process and intermediates useful for preparing cephalosphorins |
| EP1339723B1 (en) * | 2000-12-04 | 2006-03-08 | Pfizer Products Inc. | Process and ester derivatives useful for preparation of cephalosporins |
| US7378408B2 (en) * | 2001-11-30 | 2008-05-27 | Pfizer Inc. | Methods of treatment and formulations of cephalosporin |
| KR100710555B1 (ko) | 2001-12-04 | 2007-04-24 | 에스케이 주식회사 | 광학적으로 순수한 (ｒ)-폼 또는 (ｓ)-폼의테트라히드로퓨라닐 케톤의 제조방법 |
| PL2794627T3 (pl) | 2011-12-22 | 2019-04-30 | Alios Biopharma Inc | Podstawione nukleozydy, nukleotydy i ich analogi |
| US9441007B2 (en) | 2012-03-21 | 2016-09-13 | Alios Biopharma, Inc. | Substituted nucleosides, nucleotides and analogs thereof |
| USRE48171E1 (en) | 2012-03-21 | 2020-08-25 | Janssen Biopharma, Inc. | Substituted nucleosides, nucleotides and analogs thereof |
| UY34824A (es) | 2012-05-25 | 2013-11-29 | Janssen R & D Ireland | Nucleósidos de espirooxetano de uracilo |
| KR102327888B1 (ko) | 2012-12-21 | 2021-11-17 | 얀센 바이오파마, 인코퍼레이트. | 치환된 뉴클레오사이드, 뉴클레오타이드 및 그것의 유사체 |
| CN105254648B (zh) * | 2015-11-13 | 2018-04-03 | 广东温氏大华农生物科技有限公司 | 一种头孢维星及其钠盐的合成方法 |
| GB2575261B (en) | 2018-07-02 | 2022-03-09 | Norbrook Lab Ltd | Intermediates in the synthesis of C3-substituted cephalosporins |
| AU2019324170A1 (en) | 2018-08-23 | 2021-02-18 | Seagen, Inc. | Anti-TIGIT antibodies |
| CR20220316A (es) | 2019-12-06 | 2022-10-07 | Vertex Pharma | Tetrahidrofuranos sustituidos como moduladores de canales de sodio |
| TWI794742B (zh) | 2020-02-18 | 2023-03-01 | 美商基利科學股份有限公司 | 抗病毒化合物 |
| CN114213433B (zh) * | 2020-06-08 | 2023-03-24 | 重庆医药高等专科学校 | C-3位四氢呋喃取代的头孢菌素-铁载体耦合物的制备方法 |
| EP4323362A1 (en) | 2021-04-16 | 2024-02-21 | Gilead Sciences, Inc. | Methods of preparing carbanucleosides using amides |
| CN117794920A (zh) | 2021-06-04 | 2024-03-29 | 沃泰克斯药物股份有限公司 | N-(羟烷基(杂)芳基)四氢呋喃甲酰胺作为钠通道调节剂 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2197573A1 (en) * | 1972-09-07 | 1974-03-29 | Roussel Uclaf | 7-substd-phenylacetamido-cephalosporin derivs - - antibiotics active against streptococci and staphylococci |
| BE793448A (fr) * | 1971-12-31 | 1973-06-28 | Roussel Uclaf | Procede de preparation de nouveaux derives des cephalosporines et produits obtenus |
| BE791160A (fr) * | 1972-01-03 | 1973-05-09 | Beecham Group Ltd | Nouveaux cephemes substitues |
| BE791161A (fr) * | 1972-01-03 | 1973-05-09 | Beecham Group Ltd | Procede pour la preparation d'analogues des cephalosporines |
| NL7305936A (fi) * | 1972-05-05 | 1973-11-07 | ||
| JPS5849382A (ja) * | 1981-09-18 | 1983-03-23 | Kyowa Hakko Kogyo Co Ltd | β−ラクタム化合物 |
| GB8821797D0 (en) * | 1988-09-16 | 1988-10-19 | Beecham Group Plc | Novel compounds |
| EP0395219B1 (en) * | 1989-03-30 | 1998-09-30 | Pfizer Inc. | Cephalosporins and their homologues, process for their preparation and pharmaceutical compositions |
-
1991
- 1991-07-16 MY MYPI91001321A patent/MY106399A/en unknown
- 1991-07-22 WO PCT/GB1991/001227 patent/WO1992001695A1/en not_active Application Discontinuation
- 1991-07-22 AU AU82224/91A patent/AU648329B2/en not_active Expired
- 1991-07-22 DE DE69131714T patent/DE69131714T2/de not_active Expired - Lifetime
- 1991-07-22 CZ CS9364A patent/CZ6493A3/cs unknown
- 1991-07-22 JP JP3512255A patent/JPH05509089A/ja active Pending
- 1991-07-22 NZ NZ239061A patent/NZ239061A/en not_active IP Right Cessation
- 1991-07-22 CA CA002087967A patent/CA2087967C/en not_active Expired - Lifetime
- 1991-07-22 JP JP3512368A patent/JP2851428B2/ja not_active Expired - Lifetime
- 1991-07-22 CA CA002359744A patent/CA2359744C/en not_active Expired - Lifetime
- 1991-07-22 EP EP91913583A patent/EP0540609B1/en not_active Expired - Lifetime
- 1991-07-22 WO PCT/GB1991/001228 patent/WO1992001696A1/en active IP Right Grant
- 1991-07-22 ES ES91913583T patent/ES2137162T3/es not_active Expired - Lifetime
- 1991-07-22 AP APAP/P/1991/000305A patent/AP832A/en active
- 1991-07-22 DE DE200612000065 patent/DE122006000065I2/de active Active
- 1991-07-22 EP EP91913545A patent/EP0540606A1/en not_active Withdrawn
- 1991-07-22 IE IE256991A patent/IE912569A1/en not_active IP Right Cessation
- 1991-07-22 IL IL98909A patent/IL98909A0/xx unknown
- 1991-07-22 HU HU93177A patent/HUT63628A/hu unknown
- 1991-07-22 KR KR1019930700216A patent/KR100189075B1/ko not_active IP Right Cessation
- 1991-07-22 DK DK91913583T patent/DK0540609T3/da active
- 1991-07-22 AT AT91913583T patent/ATE185567T1/de active
- 1991-07-22 MX MX9100317A patent/MX9100317A/es unknown
- 1991-07-23 YU YU129691A patent/YU129691A/sh unknown
- 1991-07-23 PT PT98426A patent/PT98426A/pt not_active Application Discontinuation
- 1991-07-24 CN CN91105783A patent/CN1061046C/zh not_active Expired - Lifetime
-
1993
- 1993-01-22 FI FI930270A patent/FI930270A/fi unknown
- 1993-01-22 NO NO93930226A patent/NO930226L/no unknown
-
1998
- 1998-11-14 CN CN98122407A patent/CN1111410C/zh not_active Expired - Lifetime
-
1999
- 1999-11-03 GR GR990402803T patent/GR3031711T3/el unknown
-
2006
- 2006-11-22 LU LU91290C patent/LU91290I2/fr unknown
- 2006-11-27 NL NL300249C patent/NL300249I2/en unknown
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