DE122006000065I1 - Cephalosporine und ihre homologen, zubereitungen und Pharmazeutische Pr{parate - Google Patents

Cephalosporine und ihre homologen, zubereitungen und Pharmazeutische Pr{parate

Info

Publication number
DE122006000065I1
DE122006000065I1 DE200612000065 DE122006000065C DE122006000065I1 DE 122006000065 I1 DE122006000065 I1 DE 122006000065I1 DE 200612000065 DE200612000065 DE 200612000065 DE 122006000065 C DE122006000065 C DE 122006000065C DE 122006000065 I1 DE122006000065 I1 DE 122006000065I1
Authority
DE
Germany
Prior art keywords
preparations
cephalosporins
homologues
pharmaceutical
pharmaceutical preparations
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
DE200612000065
Other languages
English (en)
Other versions
DE122006000065I2 (de
Inventor
Bateson John Hargreaves
Stephen Christopher Martin Fell
George Burton
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Inc
Original Assignee
Pfizer Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB909016189A external-priority patent/GB9016189D0/en
Priority claimed from GB919109540A external-priority patent/GB9109540D0/en
Application filed by Pfizer Inc filed Critical Pfizer Inc
Publication of DE122006000065I1 publication Critical patent/DE122006000065I1/de
Publication of DE122006000065I2 publication Critical patent/DE122006000065I2/de
Active legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D463/00—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D463/10—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D463/14—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hetero atoms directly attached in position 7
    • C07D463/16—Nitrogen atoms
    • C07D463/18—Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof
    • C07D463/20—Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof with the acylating radicals further substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D463/22—Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof with the acylating radicals further substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen further substituted by nitrogen atoms
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
DE200612000065 1990-07-24 1991-07-22 Cephalosporine und ihre Homologen, Zubereitungen und pharmazeutische Pr{parate Active DE122006000065I2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB909016189A GB9016189D0 (en) 1990-07-24 1990-07-24 Novel compounds
GB919109540A GB9109540D0 (en) 1991-05-02 1991-05-02 Novel compounds
PCT/GB1991/001228 WO1992001696A1 (en) 1990-07-24 1991-07-22 Cephalosporins and homologues, preparations and pharmaceutical compositions

Publications (2)

Publication Number Publication Date
DE122006000065I1 true DE122006000065I1 (de) 2007-03-01
DE122006000065I2 DE122006000065I2 (de) 2007-09-13

Family

ID=26297372

Family Applications (2)

Application Number Title Priority Date Filing Date
DE200612000065 Active DE122006000065I2 (de) 1990-07-24 1991-07-22 Cephalosporine und ihre Homologen, Zubereitungen und pharmazeutische Pr{parate
DE69131714T Expired - Lifetime DE69131714T2 (de) 1990-07-24 1991-07-22 Cephalosporine und ihre homologen, zubereitungen und pharmazeutsiche präparate

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE69131714T Expired - Lifetime DE69131714T2 (de) 1990-07-24 1991-07-22 Cephalosporine und ihre homologen, zubereitungen und pharmazeutsiche präparate

Country Status (26)

Country Link
EP (2) EP0540606A1 (de)
JP (2) JPH05509089A (de)
KR (1) KR100189075B1 (de)
CN (2) CN1061046C (de)
AP (1) AP832A (de)
AT (1) ATE185567T1 (de)
AU (1) AU648329B2 (de)
CA (2) CA2359744C (de)
CZ (1) CZ6493A3 (de)
DE (2) DE122006000065I2 (de)
DK (1) DK0540609T3 (de)
ES (1) ES2137162T3 (de)
FI (1) FI930270A (de)
GR (1) GR3031711T3 (de)
HU (1) HUT63628A (de)
IE (1) IE912569A1 (de)
IL (1) IL98909A0 (de)
LU (1) LU91290I2 (de)
MX (1) MX9100317A (de)
MY (1) MY106399A (de)
NL (1) NL300249I2 (de)
NO (1) NO930226L (de)
NZ (1) NZ239061A (de)
PT (1) PT98426A (de)
WO (2) WO1992001695A1 (de)
YU (1) YU129691A (de)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9125645D0 (en) * 1991-12-03 1992-01-29 Smithkline Beecham Plc Novel compounds
AU3264393A (en) * 1992-01-22 1993-09-01 Smithkline Beecham Plc 2-isocephem and oxacephem derivatives, processes for their preparation, intermediates thereof and use as antibacterial agents
GB9212609D0 (en) * 1992-06-13 1992-07-29 Smithkline Beecham Plc Novel compounds
GB9213567D0 (en) * 1992-06-26 1992-08-12 Smithkline Beecham Plc Novel compounds
GB9424847D0 (en) * 1994-12-09 1995-02-08 Smithkline Beecham Plc Novel process
GB2300856A (en) * 1995-05-16 1996-11-20 Pfizer Ltd Beta-lactam preparation
WO1998014421A1 (fr) * 1996-10-02 1998-04-09 Daiichi Pharmaceutical Co., Ltd. Procede d'esterification de composes carboxyliques
FR2776292B1 (fr) * 1998-03-20 2004-09-10 Oncopharm Cephalotaxanes porteurs de chaine laterale et leur procede de synthese
GB0019124D0 (en) 2000-08-03 2000-09-27 Pfizer Novel process
ATE319719T1 (de) * 2000-12-04 2006-03-15 Pfizer Prod Inc Verfahren und esterderivate zur herstellung von cephalosphorinen
AU2394302A (en) * 2000-12-04 2002-06-18 Pfizer Prod Inc Coupling process and intermediates useful for preparing cephalosphorins
US7378408B2 (en) * 2001-11-30 2008-05-27 Pfizer Inc. Methods of treatment and formulations of cephalosporin
KR100710555B1 (ko) 2001-12-04 2007-04-24 에스케이 주식회사 광학적으로 순수한 (ｒ)-폼 또는 (ｓ)-폼의테트라히드로퓨라닐 케톤의 제조방법
US9073960B2 (en) 2011-12-22 2015-07-07 Alios Biopharma, Inc. Substituted nucleosides, nucleotides and analogs thereof
US9441007B2 (en) 2012-03-21 2016-09-13 Alios Biopharma, Inc. Substituted nucleosides, nucleotides and analogs thereof
USRE48171E1 (en) 2012-03-21 2020-08-25 Janssen Biopharma, Inc. Substituted nucleosides, nucleotides and analogs thereof
EP2861611B1 (de) 2012-05-25 2016-07-13 Janssen Sciences Ireland UC Uracyl-spirooxetan-nukleoside
WO2014100505A1 (en) 2012-12-21 2014-06-26 Alios Biopharma, Inc. Substituted nucleosides, nucleotides and analogs thereof
CN105254648B (zh) * 2015-11-13 2018-04-03 广东温氏大华农生物科技有限公司 一种头孢维星及其钠盐的合成方法
GB2575261B (en) 2018-07-02 2022-03-09 Norbrook Lab Ltd Intermediates in the synthesis of C3-substituted cephalosporins
BR112021003156A2 (pt) 2018-08-23 2021-05-11 Seagen, Inc. composição, anticorpo que se liga ao tigit humano, formulação farmacêutica, polinucleotídeo isolado, vetor, célula hospedeira, métodos para a produção de um anticorpo que se liga ao tigit humano e de anticorpos afucosilados que se ligam a tigit e para o tratamento de um câncer, e, kit.
AR120680A1 (es) 2019-12-06 2022-03-09 Vertex Pharma Tetrahidrofuranos sustituidos como moduladores de canales de sodio
TW202245800A (zh) 2020-02-18 2022-12-01 美商基利科學股份有限公司 抗病毒化合物
CN118598916A (zh) 2020-02-18 2024-09-06 吉利德科学公司 抗病毒化合物
TWI794742B (zh) 2020-02-18 2023-03-01 美商基利科學股份有限公司 抗病毒化合物
CN114213433B (zh) * 2020-06-08 2023-03-24 重庆医药高等专科学校 C-3位四氢呋喃取代的头孢菌素-铁载体耦合物的制备方法
US11697666B2 (en) 2021-04-16 2023-07-11 Gilead Sciences, Inc. Methods of preparing carbanucleosides using amides
AR126073A1 (es) 2021-06-04 2023-09-06 Vertex Pharma N-(hidroxialquil(hetero)aril)tetrahidrofuran carboxamidas como moduladores de canales de sodio
CA3228162A1 (en) 2021-08-18 2023-02-23 Gilead Sciences, Inc. Phospholipid compounds and methods of making and using the same

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2197573A1 (en) * 1972-09-07 1974-03-29 Roussel Uclaf 7-substd-phenylacetamido-cephalosporin derivs - - antibiotics active against streptococci and staphylococci
BE793448A (fr) * 1971-12-31 1973-06-28 Roussel Uclaf Procede de preparation de nouveaux derives des cephalosporines et produits obtenus
BE791161A (fr) * 1972-01-03 1973-05-09 Beecham Group Ltd Procede pour la preparation d'analogues des cephalosporines
BE791160A (fr) * 1972-01-03 1973-05-09 Beecham Group Ltd Nouveaux cephemes substitues
NL7305936A (de) * 1972-05-05 1973-11-07
JPS5849382A (ja) * 1981-09-18 1983-03-23 Kyowa Hakko Kogyo Co Ltd β−ラクタム化合物
GB8821797D0 (en) * 1988-09-16 1988-10-19 Beecham Group Plc Novel compounds
ES2121745T3 (es) * 1989-03-30 1998-12-16 Pfizer Cefalosporinas y sus homologos, procedimiento para su preparacion y composiciones farmaceuticas.

Also Published As

Publication number Publication date
NO930226L (no) 1993-03-23
AU648329B2 (en) 1994-04-21
WO1992001695A1 (en) 1992-02-06
CA2087967A1 (en) 1992-01-25
CA2359744C (en) 2007-02-13
CA2359744A1 (en) 1992-02-06
CN1223859A (zh) 1999-07-28
CN1111410C (zh) 2003-06-18
NL300249I1 (nl) 2007-02-01
AP9100305A0 (en) 1991-07-31
AP832A (en) 2000-05-03
JP2851428B2 (ja) 1999-01-27
JPH05509089A (ja) 1993-12-16
AU8222491A (en) 1992-02-18
MX9100317A (es) 1992-02-28
CN1061046C (zh) 2001-01-24
LU91290I2 (fr) 2007-01-22
HUT63628A (en) 1993-09-28
NO930226D0 (no) 1993-01-22
JPH05509305A (ja) 1993-12-22
NL300249I2 (en) 2007-02-01
KR100189075B1 (ko) 1999-06-01
KR930701456A (ko) 1993-06-11
HU9300177D0 (en) 1993-04-28
MY106399A (en) 1995-05-30
PT98426A (pt) 1992-05-29
IE912569A1 (en) 1992-01-29
FI930270A (fi) 1993-03-22
GR3031711T3 (en) 2000-02-29
IL98909A0 (en) 1992-07-15
EP0540609B1 (de) 1999-10-13
FI930270A0 (fi) 1993-01-22
YU129691A (sh) 1994-01-20
CN1060469A (zh) 1992-04-22
EP0540609A1 (de) 1993-05-12
DE69131714D1 (de) 1999-11-18
WO1992001696A1 (en) 1992-02-06
ATE185567T1 (de) 1999-10-15
DK0540609T3 (da) 1999-12-27
CA2087967C (en) 2002-09-10
DE122006000065I2 (de) 2007-09-13
ES2137162T3 (es) 1999-12-16
CZ6493A3 (en) 1994-04-13
NZ239061A (en) 1993-11-25
DE69131714T2 (de) 2000-02-24
EP0540606A1 (de) 1993-05-12

Similar Documents

Publication Publication Date Title
DE122006000065I2 (de) Cephalosporine und ihre Homologen, Zubereitungen und pharmazeutische Pr{parate
NO922005D0 (no) Farmasoeytiske preparater
DK0539319T3 (da) Farmaceutisk cyclosporinpræparat
FI915826A0 (fi) Farmaceutiska aemnen.
DK0515312T3 (da) Farmaceutisk præparat
DE69101931D1 (de) Pharmazeutische Zusammensetzung.
DE69011059D1 (de) Heterozyklische Acylaminothiazolderivate, ihre Herstellung und diese enthaltende pharmazeutische Zubereitungen.
ATA154489A (de) Feste pharmazeutische ranitidinpraeparate
DE69325408D1 (de) Pharmazeutische Zubereitung in wässriger Suspensionsform
DK162491D0 (da) Heterocycliske forbindelser, deres fremstilling og farmaceutiske praeparater indeholdende forbindelserne
FI961938A (fi) Uudet taksoidit, niiden valmistus ja niitä sisältävät farmaseuttiset valmisteet
DK137591D0 (da) Fast farmaceutisk praeparat
FI923371A0 (fi) En farmaceutisk formulation.
DE58905160D1 (de) Pharmazeutische zubereitung.
FI934317A0 (fi) Farmaceutiska sammansaettningar, vilka innehaoller ej-joniska ytaktiva aemnen
KR920007598U (ko) 의약용 캅셀
DK207590D0 (da) Farmaceutisk praeparat
DK204190D0 (da) Farmaceutisk praeparat
DK75791D0 (da) Novel pharmaceutical preparations
NO920564D0 (no) Farmasoeytiske adenosinholdige preparater
SE9302429D0 (sv) New pharmaceutical preparation ii
ZA915725B (en) Cephalosporins and homologues,preparations and pharmaceutical compositions
DK162391D0 (da) Heterocycliske forbindelser, deres fremstilling og farmaceutiske praeparater indeholdende forbindelserne
DK162291D0 (da) Heterocycliske forbindelser, deres fremstilling og farmaceutiske praeparater indeholdende forbindelserne
NO920039L (no) Farmasoeytiske preparater