DE69331047T2 - 2-isocephem und -oxacephemderivate,verfahren zu deren herstellung, deren zwischenprodukte und verwendung als antibakterielle mittel - Google Patents

2-isocephem und -oxacephemderivate,verfahren zu deren herstellung, deren zwischenprodukte und verwendung als antibakterielle mittel

Info

Publication number
DE69331047T2
DE69331047T2 DE69331047T DE69331047T DE69331047T2 DE 69331047 T2 DE69331047 T2 DE 69331047T2 DE 69331047 T DE69331047 T DE 69331047T DE 69331047 T DE69331047 T DE 69331047T DE 69331047 T2 DE69331047 T2 DE 69331047T2
Authority
DE
Germany
Prior art keywords
isocephem
production
antibacterial agent
intermediate products
oxacephem
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69331047T
Other languages
English (en)
Other versions
DE69331047D1 (de
Inventor
George Burton
Brian Charles Gasson
Stephen Christopher Marti Fell
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Inc
Original Assignee
Pfizer Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB929201290A external-priority patent/GB9201290D0/en
Priority claimed from GB929201291A external-priority patent/GB9201291D0/en
Application filed by Pfizer Inc filed Critical Pfizer Inc
Publication of DE69331047D1 publication Critical patent/DE69331047D1/de
Application granted granted Critical
Publication of DE69331047T2 publication Critical patent/DE69331047T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cephalosporin Compounds (AREA)
DE69331047T 1992-01-22 1993-01-14 2-isocephem und -oxacephemderivate,verfahren zu deren herstellung, deren zwischenprodukte und verwendung als antibakterielle mittel Expired - Fee Related DE69331047T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB929201290A GB9201290D0 (en) 1992-01-22 1992-01-22 Novel compounds
GB929201291A GB9201291D0 (en) 1992-01-22 1992-01-22 Novel compounds
PCT/GB1993/000068 WO1993015085A1 (en) 1992-01-22 1993-01-14 2-isocephem and oxacephem derivatives, processes for their preparation, intermediates thereof and use as antibacterial agents

Publications (2)

Publication Number Publication Date
DE69331047D1 DE69331047D1 (de) 2001-12-06
DE69331047T2 true DE69331047T2 (de) 2002-03-21

Family

ID=26300193

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69331047T Expired - Fee Related DE69331047T2 (de) 1992-01-22 1993-01-14 2-isocephem und -oxacephemderivate,verfahren zu deren herstellung, deren zwischenprodukte und verwendung als antibakterielle mittel

Country Status (6)

Country Link
US (1) US5578591A (de)
EP (1) EP0624160B1 (de)
JP (1) JPH07503460A (de)
AU (1) AU3264393A (de)
DE (1) DE69331047T2 (de)
WO (1) WO1993015085A1 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5016345A (en) * 1989-08-17 1991-05-21 Mecanismos Auxiliares Industriales, S.A. Apparatus for assembling wire harnesses
US5919925A (en) * 1992-01-22 1999-07-06 Pfizer Inc. 2-isocephem and oxacephem derivatives and use as antibacterial agents
CA2143519A1 (en) * 1994-03-11 1995-09-12 Markus Bohringer Beta-lactams
US5811419A (en) * 1996-01-16 1998-09-22 Hoffmann-La Roche Inc. Isooxacephem-derivatives
US6004954A (en) * 1996-03-13 1999-12-21 Takeda Chemical Industries, Ltd. Condensed thiazine derivatives, their production and use thereof
US6403369B1 (en) 2001-01-19 2002-06-11 Gary W. Wood Cell culture vessel
DE102005005264A1 (de) * 2005-02-04 2006-08-10 Patent-Treuhand-Gesellschaft für elektrische Glühlampen mbH Einseitig gesockelte Lampe

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4440682A (en) * 1981-04-06 1984-04-03 Laboratorio Farmaceutico Quimico "Lafarquim, S.A." Stereospecific synthesis of isocephalosporins and 2-oxa isocephalosporins
FR2559486B1 (fr) * 1984-02-13 1988-02-12 Roussel Uclaf Nouveaux derives de l'acide 1-dethia 2-thia cephalosporanique, leur procede de preparation et leur application comme medicaments
US5385897A (en) * 1985-08-09 1995-01-31 Roussel-Uclaf 4-thia-1-aza-bicyclo[4,2,0]oct-2-ene derivatives
DE69027286T2 (de) * 1989-12-29 1996-12-19 Otsuka Pharma Co Ltd Cephalosporin-Derivate, Verfahren zu ihrer Herstellung und diese Derivate enthaltende antimikrobielle Zusammensetzung
MY106399A (en) * 1990-07-24 1995-05-30 Pfizer Cephalosporins and homologeus, preparation and pharmaceutical composition
FR2678273B1 (fr) * 1991-06-25 1995-03-03 Roussel Uclaf Nouvelles cephalosporines comportant un noyau 2-thia cepheme, leur procede de preparation, leur application comme medicaments, et les nouveaux intermediaires obtenus.

Also Published As

Publication number Publication date
EP0624160B1 (de) 2001-10-31
DE69331047D1 (de) 2001-12-06
JPH07503460A (ja) 1995-04-13
AU3264393A (en) 1993-09-01
EP0624160A1 (de) 1994-11-17
US5578591A (en) 1996-11-26
WO1993015085A1 (en) 1993-08-05

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee