FI893809A - Menetelmä terapeuttisesti käyttökelpoisten fungisidisten triatsoliyhdisteiden valmistamiseksi - Google Patents

Menetelmä terapeuttisesti käyttökelpoisten fungisidisten triatsoliyhdisteiden valmistamiseksi Download PDF

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Publication number
FI893809A
FI893809A FI893809A FI893809A FI893809A FI 893809 A FI893809 A FI 893809A FI 893809 A FI893809 A FI 893809A FI 893809 A FI893809 A FI 893809A FI 893809 A FI893809 A FI 893809A
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FI
Finland
Prior art keywords
preparation
therapeutically useful
triazole compounds
fungicidal triazole
useful fungicidal
Prior art date
Application number
FI893809A
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English (en)
Swedish (sv)
Other versions
FI96859C (fi
FI96859B (fi
FI893809A0 (fi
Inventor
Roger Peter Dickinson
Kenneth Richardson
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Pfizer
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Publication of FI893809A0 publication Critical patent/FI893809A0/fi
Publication of FI893809A publication Critical patent/FI893809A/fi
Application granted granted Critical
Publication of FI96859B publication Critical patent/FI96859B/fi
Publication of FI96859C publication Critical patent/FI96859C/fi

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/28—Radicals substituted by singly-bound oxygen or sulphur atoms
    • C07D213/30—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/44—Radicals substituted by doubly-bound oxygen, sulfur, or nitrogen atoms, or by two such atoms singly-bound to the same carbon atom
    • C07D213/46—Oxygen atoms
    • C07D213/50—Ketonic radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
    • C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D237/08—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/26—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D241/12—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
FI893809A 1988-08-13 1989-08-11 Menetelmä terapeuttisesti käyttökelpoisten fungisidisten triatsoliyhdisteiden valmistamiseksi FI96859C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB8819308 1988-08-13
GB888819308A GB8819308D0 (en) 1988-08-13 1988-08-13 Triazole antifungal agents

Publications (4)

Publication Number Publication Date
FI893809A0 FI893809A0 (fi) 1989-08-11
FI893809A true FI893809A (fi) 1990-02-14
FI96859B FI96859B (fi) 1996-05-31
FI96859C FI96859C (fi) 1996-09-10

Family

ID=10642109

Family Applications (1)

Application Number Title Priority Date Filing Date
FI893809A FI96859C (fi) 1988-08-13 1989-08-11 Menetelmä terapeuttisesti käyttökelpoisten fungisidisten triatsoliyhdisteiden valmistamiseksi

Country Status (39)

Country Link
US (2) US5116844A (fi)
EP (1) EP0357241B1 (fi)
JP (2) JPH0786100B2 (fi)
KR (1) KR930002729B1 (fi)
CN (1) CN1029231C (fi)
AP (1) AP104A (fi)
AR (1) AR246963A1 (fi)
AU (1) AU602638B2 (fi)
BG (1) BG60865B1 (fi)
CA (1) CA1341325C (fi)
CY (1) CY1968A (fi)
CZ (1) CZ284318B6 (fi)
DD (1) DD284010A5 (fi)
DE (1) DE68913105T2 (fi)
DK (1) DK172471B1 (fi)
ES (1) ES2062009T4 (fi)
FI (1) FI96859C (fi)
GB (1) GB8819308D0 (fi)
HK (1) HK1000320A1 (fi)
HU (2) HU205348B (fi)
IE (1) IE61412B1 (fi)
IL (1) IL91231A (fi)
IN (1) IN175438B (fi)
IS (1) IS1586B (fi)
LV (1) LV10714B (fi)
MA (1) MA21610A1 (fi)
MX (1) MX17169A (fi)
MY (1) MY105092A (fi)
NO (1) NO174101C (fi)
NZ (1) NZ230283A (fi)
OA (1) OA09126A (fi)
PE (1) PE1591A1 (fi)
PL (2) PL162953B1 (fi)
PT (1) PT91440B (fi)
RO (1) RO108453B1 (fi)
RU (2) RU1836366C (fi)
SK (1) SK476189A3 (fi)
YU (1) YU47093B (fi)
ZA (1) ZA896151B (fi)

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WO2009137611A2 (en) * 2008-05-06 2009-11-12 Board Of Regents, The University Of Texas System Treatment of pulmonary fungal infection with voriconazole via inhalation
KR20120046242A (ko) * 2009-07-08 2012-05-09 바이엘 크롭사이언스 아게 치환된 페닐(옥시/티오)알칸올 유도체
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TWI658039B (zh) * 2011-07-08 2019-05-01 維愛美製藥公司 金屬酶抑制劑化合物
TWI646088B (zh) * 2012-03-16 2019-01-01 維愛美製藥公司 金屬酶抑制劑化合物
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DE3813841A1 (de) * 1987-06-03 1988-12-15 Bayer Ag Heterocyclische hydroxyethylazole
GB8716651D0 (en) * 1987-07-15 1987-08-19 Ici Plc 2-propanol derivatives
HUT53889A (en) * 1988-03-04 1990-12-28 Sankyo Co. Ltd.,Jp Fungicides comprising triazole derivatives as active ingredient and process for producing the active ingredient

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JPH0786100B2 (ja) 1995-09-20
PT91440B (pt) 1995-05-04
RU1836366C (ru) 1993-08-23
HUT52089A (en) 1990-06-28
AU602638B2 (en) 1990-10-18
JPH02104583A (ja) 1990-04-17
MA21610A1 (fr) 1990-04-01
CZ284318B6 (cs) 1998-10-14
ES2062009T4 (es) 2006-07-01
IS1586B (is) 1996-03-01
PL163756B1 (pl) 1994-04-29
DK172471B1 (da) 1998-09-07
DK394589A (da) 1990-02-14
YU47093B (sh) 1994-12-28
SK280775B6 (sk) 2000-07-11
CZ476189A3 (cs) 1998-09-16
RO108453B1 (ro) 1994-05-31
YU158789A (en) 1991-04-30
EP0357241B1 (en) 1994-02-16
LV10714A (lv) 1995-06-20
CN1040795A (zh) 1990-03-28
PE1591A1 (es) 1991-03-16
AR246963A1 (es) 1994-10-31
AU3893089A (en) 1990-03-22
MY105092A (en) 1994-08-30
DD284010A5 (de) 1990-10-31
NO893248D0 (no) 1989-08-11
DE68913105T2 (de) 1994-05-26
BG60865B1 (bg) 1996-05-31
AP8900135A0 (en) 1989-10-31
GB8819308D0 (en) 1988-09-14
IL91231A (en) 1994-08-26
FI96859C (fi) 1996-09-10
MX17169A (es) 1993-08-01
KR930002729B1 (ko) 1993-04-09
BG89519A (bg) 1993-12-24
NO174101B (no) 1993-12-06
NZ230283A (en) 1991-02-26
NO893248L (no) 1990-02-14
LV10714B (en) 1995-12-20
DK394589D0 (da) 1989-08-11
IE892582L (en) 1990-02-13
JP2713394B2 (ja) 1998-02-16
HU205348B (en) 1992-04-28
CY1968A (en) 1997-09-05
IS3499A7 (is) 1990-02-14
FI96859B (fi) 1996-05-31
HK1000320A1 (en) 1998-02-27
US5116844A (en) 1992-05-26
HU211511A9 (en) 1995-11-28
DE68913105D1 (de) 1994-03-24
CA1341325C (en) 2001-12-11
US5364938A (en) 1994-11-15
AP104A (en) 1990-11-02
EP0357241A1 (en) 1990-03-07
OA09126A (fr) 1991-10-31
FI893809A0 (fi) 1989-08-11
CN1029231C (zh) 1995-07-05
ES2062009T3 (es) 1994-12-16
KR900003157A (ko) 1990-03-23
PL162953B1 (pl) 1994-01-31
NO174101C (no) 1994-03-16
JPH07173154A (ja) 1995-07-11
SK476189A3 (en) 2000-07-11
IN175438B (fi) 1995-06-17
IL91231A0 (en) 1990-03-19
PT91440A (pt) 1990-03-08
RU2095358C1 (ru) 1997-11-10
ZA896151B (en) 1991-03-27
IE61412B1 (en) 1994-11-02

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