DK394589D0 - 3-heterocyclyl-2-phenyl-1-(1h-1,2,4-triazol-1-yl)-alkan-2-ol-forbindelser, deres anvendelse til fremstilling af antifungale midler, farmaceutiske praeparater indeholdende forbindelserne og mellemprodukter ved fremstilling af forbindelserne - Google Patents
3-heterocyclyl-2-phenyl-1-(1h-1,2,4-triazol-1-yl)-alkan-2-ol-forbindelser, deres anvendelse til fremstilling af antifungale midler, farmaceutiske praeparater indeholdende forbindelserne og mellemprodukter ved fremstilling af forbindelserneInfo
- Publication number
- DK394589D0 DK394589D0 DK394589A DK394589A DK394589D0 DK 394589 D0 DK394589 D0 DK 394589D0 DK 394589 A DK394589 A DK 394589A DK 394589 A DK394589 A DK 394589A DK 394589 D0 DK394589 D0 DK 394589D0
- Authority
- DK
- Denmark
- Prior art keywords
- containing organic
- products containing
- organic products
- compositions
- triazol
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title 2
- -1 1H-1,2,4-TRIAZOL-1-YL Chemical class 0.000 title 1
- 229940121375 antifungal agent Drugs 0.000 title 1
- 239000003429 antifungal agent Substances 0.000 title 1
- 150000001875 compounds Chemical class 0.000 title 1
- 239000000825 pharmaceutical preparation Substances 0.000 title 1
- 238000002360 preparation method Methods 0.000 title 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/28—Radicals substituted by singly-bound oxygen or sulphur atoms
- C07D213/30—Oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/44—Radicals substituted by doubly-bound oxygen, sulfur, or nitrogen atoms, or by two such atoms singly-bound to the same carbon atom
- C07D213/46—Oxygen atoms
- C07D213/50—Ketonic radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
- C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D237/08—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/26—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
- C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D241/12—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB888819308A GB8819308D0 (en) | 1988-08-13 | 1988-08-13 | Triazole antifungal agents |
GB8819308 | 1988-08-13 |
Publications (3)
Publication Number | Publication Date |
---|---|
DK394589D0 true DK394589D0 (da) | 1989-08-11 |
DK394589A DK394589A (da) | 1990-02-14 |
DK172471B1 DK172471B1 (da) | 1998-09-07 |
Family
ID=10642109
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK198903945A DK172471B1 (da) | 1988-08-13 | 1989-08-11 | 3-Heterocyclyl-2-phenyl-1-(1H-1,2,4-triazol-1-yl)-alkan-2-ol-forbindelser, forbindelserne til anvendelse som lægemidler, fa |
Country Status (39)
Country | Link |
---|---|
US (2) | US5116844A (da) |
EP (1) | EP0357241B1 (da) |
JP (2) | JPH0786100B2 (da) |
KR (1) | KR930002729B1 (da) |
CN (1) | CN1029231C (da) |
AP (1) | AP104A (da) |
AR (1) | AR246963A1 (da) |
AU (1) | AU602638B2 (da) |
BG (1) | BG60865B1 (da) |
CA (1) | CA1341325C (da) |
CY (1) | CY1968A (da) |
CZ (1) | CZ284318B6 (da) |
DD (1) | DD284010A5 (da) |
DE (1) | DE68913105T2 (da) |
DK (1) | DK172471B1 (da) |
ES (1) | ES2062009T4 (da) |
FI (1) | FI96859C (da) |
GB (1) | GB8819308D0 (da) |
HK (1) | HK1000320A1 (da) |
HU (2) | HU205348B (da) |
IE (1) | IE61412B1 (da) |
IL (1) | IL91231A (da) |
IN (1) | IN175438B (da) |
IS (1) | IS1586B (da) |
LV (1) | LV10714B (da) |
MA (1) | MA21610A1 (da) |
MX (1) | MX17169A (da) |
MY (1) | MY105092A (da) |
NO (1) | NO174101C (da) |
NZ (1) | NZ230283A (da) |
OA (1) | OA09126A (da) |
PE (1) | PE1591A1 (da) |
PL (2) | PL162953B1 (da) |
PT (1) | PT91440B (da) |
RO (1) | RO108453B1 (da) |
RU (2) | RU1836366C (da) |
SK (1) | SK280775B6 (da) |
YU (1) | YU47093B (da) |
ZA (1) | ZA896151B (da) |
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GB9317491D0 (en) * | 1993-08-23 | 1993-10-06 | Fujisawa Pharmaceutical Co | New compound and a process for preparation thereof |
SE508401C2 (sv) * | 1993-06-09 | 1998-10-05 | Sca Hygiene Prod Ab | Absorberande struktur och absorberande alster, som innefattar strukturen ifråga |
NZ270418A (en) * | 1994-02-07 | 1997-09-22 | Eisai Co Ltd | Polycyclic triazole & imidazole derivatives, antifungal compositions |
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CA2180091A1 (en) * | 1995-07-08 | 1997-01-09 | Hiroki Kodama | Optically active triazole derivative, process for producing the same, antifungal agent, and method for using the same |
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GB9713149D0 (en) * | 1997-06-21 | 1997-08-27 | Pfizer Ltd | Pharmaceutical formulations |
ES2159488B1 (es) * | 2000-03-07 | 2002-04-16 | Uriach & Cia Sa J | Procedimiento para la preparacion de derivados de pirimidona con actividad antifungica. |
FR2814073B1 (fr) * | 2000-09-21 | 2005-06-24 | Yang Ji Chemical Company Ltd | Composition pharmaceutique antifongique et/ou antiparasitaire et nouveaux derives de l'indole a titre de principes actifs d'une telle composition |
KR100572996B1 (ko) * | 2003-08-12 | 2006-04-25 | 한국화학연구원 | 불소화 비닐 에테르 측쇄기를 갖는 아졸계 살균제 화합물및 그의 제조방법 |
AR061889A1 (es) | 2006-07-13 | 2008-10-01 | Medichem Sa | Proceso mejorado para la preparacion de voriconazol |
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US20110224232A1 (en) * | 2008-05-06 | 2011-09-15 | Board Of Regents, The University Of Texas System | Treatment of Pulmonary Fungal Infection With Voriconazole via Inhalation |
CN102471285B (zh) * | 2009-07-08 | 2015-04-22 | 拜耳作物科学公司 | 取代的苯基(氧基/硫基)烷醇衍生物 |
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CA2837400C (en) * | 2010-04-24 | 2017-12-12 | Viamet Pharmaceuticals, Inc. | 5-(optionally substituted phenyl) pyridin-2-yl compounds as metalloenzyme inhibitors |
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CN102796087B (zh) * | 2012-09-04 | 2015-04-15 | 西南大学 | 香豆素三唑醇及其制备方法和用途 |
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JP6387401B2 (ja) | 2013-05-28 | 2018-09-05 | ヴィアメット ファーマスーティカルズ(エヌシー),インコーポレイテッド | 殺真菌組成物 |
RU2563811C1 (ru) * | 2014-08-08 | 2015-09-20 | Федеральное государственное бюджетное учреждение науки Институт химической физики им. Н.Н. Семенова Российской академии наук (ИХФ РАН) | Фармацевтическая композиция для лечения грибковых заболеваний |
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GB8313235D0 (en) * | 1983-05-13 | 1983-06-22 | Pfizer Ltd | Antifungal agents |
DE3325313A1 (de) * | 1983-07-13 | 1985-01-31 | Bayer Ag, 5090 Leverkusen | Fungizide mittel, deren herstellung und verwendung |
US4483863A (en) * | 1984-01-20 | 1984-11-20 | Pfizer Inc. | Triazole antifungal agents |
IE58738B1 (en) * | 1984-09-05 | 1993-11-03 | Ici Plc | Antifungal azole compounds |
DE3440117A1 (de) * | 1984-11-02 | 1986-05-15 | Bayer Ag, 5090 Leverkusen | Substituierte azolylcyclopropyl-azolylmethyl-carbinol-derivate |
GB8506619D0 (en) * | 1985-03-14 | 1985-04-17 | Pfizer Ltd | Triazole antifungal agents |
JPS6360975A (ja) * | 1986-06-23 | 1988-03-17 | ザ・デュポン・メルク・ファーマシュウティカル・カンパニー | 抗真菌性カルビノ−ル類 |
DE3813841A1 (de) * | 1987-06-03 | 1988-12-15 | Bayer Ag | Heterocyclische hydroxyethylazole |
GB8716651D0 (en) * | 1987-07-15 | 1987-08-19 | Ici Plc | 2-propanol derivatives |
HUT53889A (en) * | 1988-03-04 | 1990-12-28 | Sankyo Co. Ltd.,Jp | Fungicides comprising triazole derivatives as active ingredient and process for producing the active ingredient |
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1988
- 1988-08-13 GB GB888819308A patent/GB8819308D0/en active Pending
-
1989
- 1989-07-18 IN IN634DE1989 patent/IN175438B/en unknown
- 1989-07-24 AU AU38930/89A patent/AU602638B2/en not_active Expired
- 1989-07-31 PE PE1989157445A patent/PE1591A1/es unknown
- 1989-08-03 EP EP89307920A patent/EP0357241B1/en not_active Expired - Lifetime
- 1989-08-03 DE DE68913105T patent/DE68913105T2/de not_active Expired - Lifetime
- 1989-08-03 ES ES89307920T patent/ES2062009T4/es not_active Expired - Lifetime
- 1989-08-07 IL IL9123189A patent/IL91231A/en active Protection Beyond IP Right Term
- 1989-08-08 MA MA21863A patent/MA21610A1/fr unknown
- 1989-08-10 IS IS3499A patent/IS1586B/is unknown
- 1989-08-10 MY MYPI89001091A patent/MY105092A/en unknown
- 1989-08-10 SK SK4761-89A patent/SK280775B6/sk unknown
- 1989-08-10 CZ CS894761A patent/CZ284318B6/cs not_active IP Right Cessation
- 1989-08-10 AP APAP/P/1989/000135A patent/AP104A/en active
- 1989-08-11 RU SU894614663A patent/RU1836366C/ru active
- 1989-08-11 AR AR89314635A patent/AR246963A1/es active
- 1989-08-11 FI FI893809A patent/FI96859C/fi active IP Right Grant
- 1989-08-11 ZA ZA896151A patent/ZA896151B/xx unknown
- 1989-08-11 BG BG89519A patent/BG60865B1/bg unknown
- 1989-08-11 PT PT91440A patent/PT91440B/pt not_active IP Right Cessation
- 1989-08-11 IE IE258289A patent/IE61412B1/en not_active IP Right Cessation
- 1989-08-11 NO NO893248A patent/NO174101C/no not_active IP Right Cessation
- 1989-08-11 CA CA000608083A patent/CA1341325C/en not_active Expired - Lifetime
- 1989-08-11 NZ NZ230283A patent/NZ230283A/xx unknown
- 1989-08-11 US US07/392,686 patent/US5116844A/en not_active Expired - Lifetime
- 1989-08-11 HU HU894151A patent/HU205348B/hu unknown
- 1989-08-11 MX MX1716989A patent/MX17169A/es unknown
- 1989-08-11 RO RO141245A patent/RO108453B1/ro unknown
- 1989-08-11 YU YU158789A patent/YU47093B/sh unknown
- 1989-08-11 JP JP1209513A patent/JPH0786100B2/ja not_active Expired - Lifetime
- 1989-08-11 PL PL28102089A patent/PL162953B1/pl unknown
- 1989-08-11 PL PL89297228A patent/PL163756B1/pl unknown
- 1989-08-11 OA OA59624A patent/OA09126A/xx unknown
- 1989-08-11 DK DK198903945A patent/DK172471B1/da not_active IP Right Cessation
- 1989-08-12 CN CN89106679A patent/CN1029231C/zh not_active Expired - Lifetime
- 1989-08-12 KR KR1019890011503A patent/KR930002729B1/ko not_active IP Right Cessation
- 1989-08-14 DD DD89331760A patent/DD284010A5/de not_active IP Right Cessation
-
1992
- 1992-03-05 RU SU925010979A patent/RU2095358C1/ru active
-
1993
- 1993-03-04 US US08/026,671 patent/US5364938A/en not_active Expired - Lifetime
- 1993-11-15 LV LVP-93-1223A patent/LV10714B/lv unknown
-
1994
- 1994-12-12 JP JP6307468A patent/JP2713394B2/ja not_active Expired - Lifetime
-
1995
- 1995-06-26 HU HU95P/P00436P patent/HU211511A9/hu unknown
-
1997
- 1997-09-05 CY CY196897A patent/CY1968A/xx unknown
- 1997-09-26 HK HK97101863A patent/HK1000320A1/xx not_active IP Right Cessation
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Legal Events
Date | Code | Title | Description |
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B1 | Patent granted (law 1993) | ||
PUP | Patent expired |