DK394589A - 3-heterocyclyl-2-phenyl-1-(1h-1,2,4-triazol-1-yl)-alkan-2-ol-forbindelser, deres anvendelse til fremstilling af antifungale midler, farmaceutiske praeparater indeholdende forbindelserne og mellemprodukter ved fremstilling af forbindelserne - Google Patents

3-heterocyclyl-2-phenyl-1-(1h-1,2,4-triazol-1-yl)-alkan-2-ol-forbindelser, deres anvendelse til fremstilling af antifungale midler, farmaceutiske praeparater indeholdende forbindelserne og mellemprodukter ved fremstilling af forbindelserne Download PDF

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DK394589A
DK394589A DK394589A DK394589A DK394589A DK 394589 A DK394589 A DK 394589A DK 394589 A DK394589 A DK 394589A DK 394589 A DK394589 A DK 394589A DK 394589 A DK394589 A DK 394589A
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containing organic
products containing
organic products
compositions
triazol
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DK394589A
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DK394589D0 (da
DK172471B1 (da
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Roger Peter Dickinson
Kenneth Richardson
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Pfizer
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/28—Radicals substituted by singly-bound oxygen or sulphur atoms
    • C07D213/30—Oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/44—Radicals substituted by doubly-bound oxygen, sulfur, or nitrogen atoms, or by two such atoms singly-bound to the same carbon atom
    • C07D213/46—Oxygen atoms
    • C07D213/50—Ketonic radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
    • C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D237/08—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/26—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D241/12—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
DK198903945A 1988-08-13 1989-08-11 3-Heterocyclyl-2-phenyl-1-(1H-1,2,4-triazol-1-yl)-alkan-2-ol-forbindelser, forbindelserne til anvendelse som lægemidler, fa DK172471B1 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB8819308 1988-08-13
GB888819308A GB8819308D0 (en) 1988-08-13 1988-08-13 Triazole antifungal agents

Publications (3)

Publication Number Publication Date
DK394589D0 DK394589D0 (da) 1989-08-11
DK394589A true DK394589A (da) 1990-02-14
DK172471B1 DK172471B1 (da) 1998-09-07

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ID=10642109

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DK198903945A DK172471B1 (da) 1988-08-13 1989-08-11 3-Heterocyclyl-2-phenyl-1-(1H-1,2,4-triazol-1-yl)-alkan-2-ol-forbindelser, forbindelserne til anvendelse som lægemidler, fa

Country Status (39)

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US (2) US5116844A (da)
EP (1) EP0357241B1 (da)
JP (2) JPH0786100B2 (da)
KR (1) KR930002729B1 (da)
CN (1) CN1029231C (da)
AP (1) AP104A (da)
AR (1) AR246963A1 (da)
AU (1) AU602638B2 (da)
BG (1) BG60865B1 (da)
CA (1) CA1341325C (da)
CY (1) CY1968A (da)
CZ (1) CZ284318B6 (da)
DD (1) DD284010A5 (da)
DE (1) DE68913105T2 (da)
DK (1) DK172471B1 (da)
ES (1) ES2062009T4 (da)
FI (1) FI96859C (da)
GB (1) GB8819308D0 (da)
HK (1) HK1000320A1 (da)
HU (2) HU205348B (da)
IE (1) IE61412B1 (da)
IL (1) IL91231A (da)
IN (1) IN175438B (da)
IS (1) IS1586B (da)
LV (1) LV10714B (da)
MA (1) MA21610A1 (da)
MX (1) MX17169A (da)
MY (1) MY105092A (da)
NO (1) NO174101C (da)
NZ (1) NZ230283A (da)
OA (1) OA09126A (da)
PE (1) PE1591A1 (da)
PL (2) PL162953B1 (da)
PT (1) PT91440B (da)
RO (1) RO108453B1 (da)
RU (2) RU1836366C (da)
SK (1) SK280775B6 (da)
YU (1) YU47093B (da)
ZA (1) ZA896151B (da)

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PT91440A (pt) 1990-03-08
ES2062009T4 (es) 2006-07-01
AR246963A1 (es) 1994-10-31
MX17169A (es) 1993-08-01
DE68913105D1 (de) 1994-03-24
LV10714B (en) 1995-12-20
YU47093B (sh) 1994-12-28
HUT52089A (en) 1990-06-28
CZ284318B6 (cs) 1998-10-14
IE61412B1 (en) 1994-11-02
DK394589D0 (da) 1989-08-11
EP0357241A1 (en) 1990-03-07
IL91231A0 (en) 1990-03-19
AP104A (en) 1990-11-02
NO174101B (no) 1993-12-06
HU211511A9 (en) 1995-11-28
IS3499A7 (is) 1990-02-14
HU205348B (en) 1992-04-28
EP0357241B1 (en) 1994-02-16
DE68913105T2 (de) 1994-05-26
NO893248D0 (no) 1989-08-11
GB8819308D0 (en) 1988-09-14
ZA896151B (en) 1991-03-27
JPH0786100B2 (ja) 1995-09-20
IN175438B (da) 1995-06-17
LV10714A (lv) 1995-06-20
JP2713394B2 (ja) 1998-02-16
FI96859B (fi) 1996-05-31
ES2062009T3 (es) 1994-12-16
MA21610A1 (fr) 1990-04-01
RO108453B1 (ro) 1994-05-31
PL163756B1 (pl) 1994-04-29
FI893809A0 (fi) 1989-08-11
CY1968A (en) 1997-09-05
CN1040795A (zh) 1990-03-28
US5116844A (en) 1992-05-26
CZ476189A3 (cs) 1998-09-16
IE892582L (en) 1990-02-13
OA09126A (fr) 1991-10-31
AU3893089A (en) 1990-03-22
RU2095358C1 (ru) 1997-11-10
NZ230283A (en) 1991-02-26
MY105092A (en) 1994-08-30
PT91440B (pt) 1995-05-04
BG89519A (bg) 1993-12-24
IL91231A (en) 1994-08-26
SK476189A3 (en) 2000-07-11
NO893248L (no) 1990-02-14
PL162953B1 (pl) 1994-01-31
YU158789A (en) 1991-04-30
RU1836366C (ru) 1993-08-23
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DK172471B1 (da) 1998-09-07
NO174101C (no) 1994-03-16
AP8900135A0 (en) 1989-10-31
US5364938A (en) 1994-11-15
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KR900003157A (ko) 1990-03-23
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IS1586B (is) 1996-03-01
DD284010A5 (de) 1990-10-31
KR930002729B1 (ko) 1993-04-09
FI96859C (fi) 1996-09-10

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