FI77247C - Foerfarande foer framstaellning av sorbinil eller dess salt och i foerfarandet anvaendbar mellanprodukt. - Google Patents

Foerfarande foer framstaellning av sorbinil eller dess salt och i foerfarandet anvaendbar mellanprodukt. Download PDF

Info

Publication number
FI77247C
FI77247C FI834088A FI834088A FI77247C FI 77247 C FI77247 C FI 77247C FI 834088 A FI834088 A FI 834088A FI 834088 A FI834088 A FI 834088A FI 77247 C FI77247 C FI 77247C
Authority
FI
Finland
Prior art keywords
sorbinil
salt
aminomethylpinane
methanol
pharmaceutically acceptable
Prior art date
Application number
FI834088A
Other languages
English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI77247B (fi
FI834088A0 (fi
FI834088A (fi
Inventor
Jr Berkeley Wendell Cue
Philip Dietrich Hammen
Stephen Sargent Massett
Bernard Shields Moore
Robert John Sysko
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/440,657 external-priority patent/US4431828A/en
Priority claimed from US06/440,641 external-priority patent/US4435578A/en
Application filed by Pfizer filed Critical Pfizer
Publication of FI834088A0 publication Critical patent/FI834088A0/fi
Publication of FI834088A publication Critical patent/FI834088A/fi
Priority to FI880465A priority Critical patent/FI880465A/fi
Priority to FI880466A priority patent/FI880466A/fi
Publication of FI77247B publication Critical patent/FI77247B/fi
Application granted granted Critical
Publication of FI77247C publication Critical patent/FI77247C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/10—Spiro-condensed systems
    • C07D491/107—Spiro-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Hydrogenated Pyridines (AREA)
FI834088A 1982-11-10 1983-11-08 Foerfarande foer framstaellning av sorbinil eller dess salt och i foerfarandet anvaendbar mellanprodukt. FI77247C (fi)

Priority Applications (2)

Application Number Priority Date Filing Date Title
FI880465A FI880465A (fi) 1982-11-10 1988-02-02 Foerfarande foer framstaellning av ett kristallint s-6-fluor-4-ureidokroman-4-karboxylsyrasalt.
FI880466A FI880466A (fi) 1982-11-10 1988-02-02 Foerfarande foer regenerering av renat 6-fluor-4-kromanon.

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US44068682A 1982-11-10 1982-11-10
US44064182 1982-11-10
US06/440,657 US4431828A (en) 1982-11-10 1982-11-10 Regeneration of 6-fluoro-4-chromanone from by-products in the synthesis of sorbinil
US44065782 1982-11-10
US06/440,641 US4435578A (en) 1982-11-10 1982-11-10 Sorbinil by optical resolution of precursor 6-fluoro-4-ureidochroman-4-carboxylic acid
US44068682 1982-11-10

Publications (4)

Publication Number Publication Date
FI834088A0 FI834088A0 (fi) 1983-11-08
FI834088A FI834088A (fi) 1984-05-11
FI77247B FI77247B (fi) 1988-10-31
FI77247C true FI77247C (fi) 1989-02-10

Family

ID=27412063

Family Applications (1)

Application Number Title Priority Date Filing Date
FI834088A FI77247C (fi) 1982-11-10 1983-11-08 Foerfarande foer framstaellning av sorbinil eller dess salt och i foerfarandet anvaendbar mellanprodukt.

Country Status (16)

Country Link
KR (1) KR870000867B1 (xx)
AU (1) AU540399B2 (xx)
BG (1) BG44206A3 (xx)
CS (1) CS266560B2 (xx)
DD (1) DD213924A5 (xx)
DK (1) DK512683A (xx)
ES (3) ES8506040A1 (xx)
FI (1) FI77247C (xx)
GR (1) GR79017B (xx)
IL (2) IL70165A (xx)
NO (1) NO161916C (xx)
NZ (1) NZ206189A (xx)
PL (1) PL139713B1 (xx)
PT (1) PT77617B (xx)
SU (1) SU1209030A3 (xx)
YU (2) YU44867B (xx)

Also Published As

Publication number Publication date
YU220383A (en) 1988-02-29
NO161916B (no) 1989-07-03
SU1209030A3 (ru) 1986-01-30
ES534920A0 (es) 1985-09-16
NO834086L (no) 1984-05-11
CS266560B2 (en) 1990-01-12
PL244460A1 (en) 1985-03-26
FI77247B (fi) 1988-10-31
ES527118A0 (es) 1985-06-16
PL139713B1 (en) 1987-02-28
YU44867B (en) 1991-04-30
DD213924A5 (de) 1984-09-26
FI834088A0 (fi) 1983-11-08
IL70165A (en) 1987-12-20
CS827183A2 (en) 1989-04-14
PT77617A (en) 1983-12-01
AU2110583A (en) 1984-05-17
NZ206189A (en) 1987-06-30
IL81648A0 (en) 1987-09-16
ES8506040A1 (es) 1985-06-16
GR79017B (xx) 1984-10-02
IL70165A0 (en) 1984-02-29
ES8600269A1 (es) 1985-09-16
KR870000867B1 (ko) 1987-04-30
FI834088A (fi) 1984-05-11
AU540399B2 (en) 1984-11-15
ES8505988A1 (es) 1985-06-16
BG44206A3 (en) 1988-10-14
YU140985A (en) 1986-04-30
DK512683D0 (da) 1983-11-09
ES534921A0 (es) 1985-06-16
PT77617B (en) 1986-05-12
DK512683A (da) 1984-05-11
KR840006806A (ko) 1984-12-03
NO161916C (no) 1989-10-11
YU43883B (en) 1989-12-31

Similar Documents

Publication Publication Date Title
KR0179946B1 (ko) 시아노시클로알킬아세트산 유도체 및 그의 제조방법
KR101291446B1 (ko) 갈란타민 하이드로브로마이드의 제조 방법
FI77247C (fi) Foerfarande foer framstaellning av sorbinil eller dess salt och i foerfarandet anvaendbar mellanprodukt.
US4435578A (en) Sorbinil by optical resolution of precursor 6-fluoro-4-ureidochroman-4-carboxylic acid
EP0109231B1 (en) Sorbinil by optical resolution with aminopinane derivatives
EP3044215B1 (en) Processes for preparing medicaments for the treatment of cardiovascular diseases and intermediates for use therein
KR920007272B1 (ko) 라세미 반-에스테르의 분리방법
EP0123832A1 (en) Process for the optical resolution of a mixture of the enantiomers of trans-3-((4-methoxyphenoxy)-methyl)-1-methyl-4-phenylpiperidine
HU193127B (en) Process for preparing spiro/chroman-4,4'-imidazoline/ derivatives
EP1817273B1 (en) Method for preparing diastereoisomers of 4-hydroxy isoleucine
EP3105214A1 (en) A new method for producing nebivolol hydrochloride of high purity
EP0320898A2 (en) Processes and compounds useful for resolving 1-methyl-3-phenylpropylamine
US4528387A (en) Sorbinil by optical resolution of precursor 6-fluoro-4-ureidochroman-4-carboxylic acid
KR870000909B1 (ko) 결정성 s-6-플루오로-4-우레이도크로만-4-카복실산염의 제조방법
JP2840956B2 (ja) 光学活性パントラクトンの製造方法
CN117447387A (zh) 一种利特昔替尼关键中间体的制备方法
JP2981386B2 (ja) （＋）−３−フェニル−５−｛２−（１−ピロリジニルメチル）ブチリル｝イソオキサゾール及びその塩の分割法
CN116528863A (zh) 制备高纯度的1-(1-(2-苄基苯氧基)丙-2-基)-2-甲基哌啶单一异构体的方法
JPS61172846A (ja) （±）−２−クロロプロピオン酸の光学分割法
CN118005549A (zh) （2s）-1-（叔丁氧羰基）-4-（甲氧基甲基）-吡咯烷-2-羧酸的精制方法
CN115611737A (zh) 一种制备苯培酸中间体的方法及其中间体
WO2006046096A2 (en) A polymorphic form of narwedine and its use in the synthesis of galantamine
MX2007008849A (es) Proceso para la preparacion de mesilato de fenoldopam.

Legal Events

Date Code Title Description
MM Patent lapsed

Owner name: PFIZER INC.