IL70165A - Preparation of sorbinil and salts thereof by resolution of the racemate and the new(-)-3-amino-methylpinane salt of sorbinil used therefor - Google Patents
Preparation of sorbinil and salts thereof by resolution of the racemate and the new(-)-3-amino-methylpinane salt of sorbinil used thereforInfo
- Publication number
- IL70165A IL70165A IL70165A IL7016583A IL70165A IL 70165 A IL70165 A IL 70165A IL 70165 A IL70165 A IL 70165A IL 7016583 A IL7016583 A IL 7016583A IL 70165 A IL70165 A IL 70165A
- Authority
- IL
- Israel
- Prior art keywords
- sorbinil
- methylpinane
- racemate
- resolution
- salts
- Prior art date
Links
- LXANPKRCLVQAOG-NSHDSACASA-N sorbinil Chemical compound C12=CC(F)=CC=C2OCC[C@@]21NC(=O)NC2=O LXANPKRCLVQAOG-NSHDSACASA-N 0.000 title 2
- 229950004311 sorbinil Drugs 0.000 title 2
- MUOITVAMHSVXLO-UHFFFAOYSA-N (4,6,6-trimethyl-3-bicyclo[3.1.1]heptanyl)methanamine Chemical class C1C(CN)C(C)C2C(C)(C)C1C2 MUOITVAMHSVXLO-UHFFFAOYSA-N 0.000 title 1
- 150000003839 salts Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/10—Spiro-condensed systems
- C07D491/107—Spiro-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Hydrogenated Pyridines (AREA)
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IL79692A IL79692A0 (en) | 1982-11-10 | 1986-08-12 | Preparation of sorbinil and salts thereof |
| IL79693A IL79693A0 (en) | 1982-11-10 | 1986-08-12 | Preparation of sorbinil and salts thereof |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US44068682A | 1982-11-10 | 1982-11-10 | |
| US06/440,641 US4435578A (en) | 1982-11-10 | 1982-11-10 | Sorbinil by optical resolution of precursor 6-fluoro-4-ureidochroman-4-carboxylic acid |
| US06/440,657 US4431828A (en) | 1982-11-10 | 1982-11-10 | Regeneration of 6-fluoro-4-chromanone from by-products in the synthesis of sorbinil |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL70165A0 IL70165A0 (en) | 1984-02-29 |
| IL70165A true IL70165A (en) | 1987-12-20 |
Family
ID=27412063
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL70165A IL70165A (en) | 1982-11-10 | 1983-11-08 | Preparation of sorbinil and salts thereof by resolution of the racemate and the new(-)-3-amino-methylpinane salt of sorbinil used therefor |
| IL81648A IL81648A0 (en) | 1982-11-10 | 1987-02-23 | Preparation of sorbinil and salts thereof by resolution of the racemate |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL81648A IL81648A0 (en) | 1982-11-10 | 1987-02-23 | Preparation of sorbinil and salts thereof by resolution of the racemate |
Country Status (16)
| Country | Link |
|---|---|
| KR (1) | KR870000867B1 (en) |
| AU (1) | AU540399B2 (en) |
| BG (1) | BG44206A3 (en) |
| CS (1) | CS266560B2 (en) |
| DD (1) | DD213924A5 (en) |
| DK (1) | DK512683A (en) |
| ES (3) | ES527118A0 (en) |
| FI (1) | FI77247C (en) |
| GR (1) | GR79017B (en) |
| IL (2) | IL70165A (en) |
| NO (1) | NO161916C (en) |
| NZ (1) | NZ206189A (en) |
| PL (1) | PL139713B1 (en) |
| PT (1) | PT77617B (en) |
| SU (1) | SU1209030A3 (en) |
| YU (2) | YU44867B (en) |
-
1983
- 1983-11-07 PT PT77617A patent/PT77617B/en not_active IP Right Cessation
- 1983-11-07 GR GR72904A patent/GR79017B/el unknown
- 1983-11-07 YU YU2203/83A patent/YU44867B/en unknown
- 1983-11-08 KR KR1019830005294A patent/KR870000867B1/en not_active Expired
- 1983-11-08 IL IL70165A patent/IL70165A/en unknown
- 1983-11-08 ES ES527118A patent/ES527118A0/en active Granted
- 1983-11-08 NZ NZ206189A patent/NZ206189A/en unknown
- 1983-11-08 FI FI834088A patent/FI77247C/en not_active IP Right Cessation
- 1983-11-08 DD DD83256455A patent/DD213924A5/en not_active IP Right Cessation
- 1983-11-08 PL PL1983244460A patent/PL139713B1/en unknown
- 1983-11-09 BG BG062988A patent/BG44206A3/en unknown
- 1983-11-09 DK DK512683A patent/DK512683A/en not_active Application Discontinuation
- 1983-11-09 SU SU833659625A patent/SU1209030A3/en active
- 1983-11-09 AU AU21105/83A patent/AU540399B2/en not_active Ceased
- 1983-11-09 NO NO834086A patent/NO161916C/en unknown
- 1983-11-09 CS CS838271A patent/CS266560B2/en unknown
-
1984
- 1984-08-06 ES ES534920A patent/ES8600269A1/en not_active Expired
- 1984-08-06 ES ES534921A patent/ES534921A0/en active Granted
-
1985
- 1985-09-09 YU YU1409/85A patent/YU43883B/en unknown
-
1987
- 1987-02-23 IL IL81648A patent/IL81648A0/en not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| ES8506040A1 (en) | 1985-06-16 |
| DD213924A5 (en) | 1984-09-26 |
| ES8505988A1 (en) | 1985-06-16 |
| GR79017B (en) | 1984-10-02 |
| NO834086L (en) | 1984-05-11 |
| FI77247B (en) | 1988-10-31 |
| KR870000867B1 (en) | 1987-04-30 |
| NZ206189A (en) | 1987-06-30 |
| NO161916B (en) | 1989-07-03 |
| AU540399B2 (en) | 1984-11-15 |
| KR840006806A (en) | 1984-12-03 |
| YU43883B (en) | 1989-12-31 |
| PT77617B (en) | 1986-05-12 |
| ES534920A0 (en) | 1985-09-16 |
| FI834088A0 (en) | 1983-11-08 |
| AU2110583A (en) | 1984-05-17 |
| BG44206A3 (en) | 1988-10-14 |
| DK512683D0 (en) | 1983-11-09 |
| ES534921A0 (en) | 1985-06-16 |
| CS266560B2 (en) | 1990-01-12 |
| IL81648A0 (en) | 1987-09-16 |
| PL244460A1 (en) | 1985-03-26 |
| CS827183A2 (en) | 1989-04-14 |
| ES8600269A1 (en) | 1985-09-16 |
| PL139713B1 (en) | 1987-02-28 |
| DK512683A (en) | 1984-05-11 |
| FI77247C (en) | 1989-02-10 |
| ES527118A0 (en) | 1985-06-16 |
| YU44867B (en) | 1991-04-30 |
| NO161916C (en) | 1989-10-11 |
| YU220383A (en) | 1988-02-29 |
| SU1209030A3 (en) | 1986-01-30 |
| PT77617A (en) | 1983-12-01 |
| FI834088L (en) | 1984-05-11 |
| YU140985A (en) | 1986-04-30 |
| IL70165A0 (en) | 1984-02-29 |
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