FI71768B - Foerbaettrade nykleinsyrareagenser och foerfarande foer deras framstaellning - Google Patents

Foerbaettrade nykleinsyrareagenser och foerfarande foer deras framstaellning Download PDF

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Publication number
FI71768B
FI71768B FI840655A FI840655A FI71768B FI 71768 B FI71768 B FI 71768B FI 840655 A FI840655 A FI 840655A FI 840655 A FI840655 A FI 840655A FI 71768 B FI71768 B FI 71768B
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FI
Finland
Prior art keywords
nucleic acid
fragments
reagents
stripe
dna
Prior art date
Application number
FI840655A
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English (en)
Finnish (fi)
Other versions
FI71768C (sv
FI840655A0 (fi
FI840655A (fi
Inventor
Airi Marjatta Palva
Hans Erik Soederlund
Tuula Marjut Ranki
Original Assignee
Orion Yhtymae Oy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Orion Yhtymae Oy filed Critical Orion Yhtymae Oy
Publication of FI840655A0 publication Critical patent/FI840655A0/fi
Priority to FI840655A priority Critical patent/FI71768C/sv
Priority to ZA85511A priority patent/ZA85511B/xx
Priority to US06/694,325 priority patent/US4731325A/en
Priority to IE202/85A priority patent/IE57652B1/en
Priority to AU38422/85A priority patent/AU577568B2/en
Priority to IT19432/85A priority patent/IT1183184B/it
Priority to BE214463A priority patent/BE901671A/fr
Priority to DK198500589A priority patent/DK174675B1/da
Priority to LU85768A priority patent/LU85768A1/fr
Priority to CA000474112A priority patent/CA1248895A/en
Priority to NO850554A priority patent/NO166543C/no
Priority to NL8500424A priority patent/NL193663C/nl
Priority to SU853856877A priority patent/SU1523053A3/ru
Priority to GB08503900A priority patent/GB2156074B/en
Priority to CH725/85A priority patent/CH671778A5/de
Priority to SE8500733A priority patent/SE463103B/sv
Priority to DE3505287A priority patent/DE3505287C2/de
Priority to JP60029207A priority patent/JPS60188100A/ja
Priority to HU85570A priority patent/HU194938B/hu
Priority to AT0044185A priority patent/AT394578B/de
Priority to FR858502188A priority patent/FR2559783B1/fr
Priority to RO117684A priority patent/RO92633B/ro
Publication of FI840655A publication Critical patent/FI840655A/fi
Application granted granted Critical
Publication of FI71768B publication Critical patent/FI71768B/fi
Publication of FI71768C publication Critical patent/FI71768C/sv

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • C12Q1/701—Specific hybridization probes
    • C12Q1/705—Specific hybridization probes for herpetoviridae, e.g. herpes simplex, varicella zoster
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means
    • C12Q1/682—Signal amplification
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
    • C12Q1/6837—Enzymatic or biochemical coupling of nucleic acids to a solid phase using probe arrays or probe chips
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
    • C12Q1/689—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Virology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Saccharide Compounds (AREA)

Claims (6)

1. Nukleinsyrareagens avsedda att användas i nukleinsyra-diagnostik, kännetecknade därav, att de 05 innefattar tvh serier av uppsättningar av huvudsakligen alternerande nukleinsyrafragment, som fär inte vara homologa till varandra och som härstammar frän en eller flera nuklein-syror tillräckligt homologa till nukleinsyran som skall identifieras, s& att den ena av serierna är inmärkt och den 10 andra är bunden vid en fast bärare och vardera av serierna innefattar ätminstone tvä men företrädesvis flera fragment.
2. Nukleinsyrareagens enligt patentkravet 1, kännetecknade därav, att de innefattar uppsättningar av 15 antingen separata eller förenade nukleinsyrafragment.
3. Nukleinsyrareagens enligt patentkraven 1-2 kännetecknade därav, att de innefattar uppsättningar av nukleinsyrafragment som antingen har eller inte har vektor- 20 härledda delar.
4. Nukleinsyrareagens enligt patentkraven 1-3 avsedda att användas i chlamydia-diagnostik kännetecknade därav, att de innefattar derivator av rekombinant-plasmiden 25 pKTHl220, som har ytterligare klonats i plasmiden pATl53 och fagen Ml3mp8 och innehäller DNA av Chlamydia trachomatis L2 bacterium, varvid rekombinant-plasmiden pKTHl220 har transformerats i värden Escherichia coli K 12 HB 101 och deponeringsnumret av värden innehällande 30 rekombinant-plasmiden pKTHl220 är DSM 2825.
5. Nukleinsyrareagens enligt patentkraven 1-3 avsedda att användas i diagnostik av Cytomegalovirus kännetecknade därav, att de innefattar derivator av 35 rekombinant-plasmiden pKTHl271, som har ytterligare klonats i plasmiden pBR322 och fagerna Ml3mp7 och M13mp8 och innehäller DNA av Cytomegalovirus AD169, varvid rekombinant-plasmiden pKTHl271 har transformerats i värden Escherichia
FI840655A 1984-02-17 1984-02-17 Förbättrade nykleinsyrareagenser och förfarande för deras framställni ng. FI71768C (sv)

Priority Applications (22)

Application Number Priority Date Filing Date Title
FI840655A FI71768C (sv) 1984-02-17 1984-02-17 Förbättrade nykleinsyrareagenser och förfarande för deras framställni ng.
ZA85511A ZA85511B (en) 1984-02-17 1985-01-22 Nucleic acid reagents,a method for their preparation and their use
US06/694,325 US4731325A (en) 1984-02-17 1985-01-24 Arrays of alternating nucleic acid fragments for hybridization arrays
IE202/85A IE57652B1 (en) 1984-02-17 1985-01-29 Improved nucleic acid reagents and methods for their preparation
AU38422/85A AU577568B2 (en) 1984-02-17 1985-02-04 Preparation of nucleic acid reagents having arrays of alternating nucleic acid fragments
IT19432/85A IT1183184B (it) 1984-02-17 1985-02-07 Reagenti acidi nucleici perfezionati e procedimenti per laloro preparazione
BE214463A BE901671A (fr) 1984-02-17 1985-02-07 Reactifs d'acide nucleique perfectionnes et procedes pour leur preparation.
DK198500589A DK174675B1 (da) 1984-02-17 1985-02-08 Nukleinsyrereagenser og fremgangsmåde til fremstilling deraf
LU85768A LU85768A1 (fr) 1984-02-17 1985-02-12 Reactifs d'acide nucleique perfectionnes et procedes pour leur preparation
CA000474112A CA1248895A (en) 1984-02-17 1985-02-12 Nucleic acid reagents, a method for their preparation and their use
NO850554A NO166543C (no) 1984-02-17 1985-02-13 Nukleinsyrereagenser og fremgangsmaate til deres fremstilling.
NL8500424A NL193663C (nl) 1984-02-17 1985-02-14 Werkwijze en kit voor het detecteren van een specifiek nucleïnezuur in een monster.
SU853856877A SU1523053A3 (ru) 1984-02-17 1985-02-15 Способ идентификации вирусов и бактерий, основанный на сэндвич-гибридизации нуклеиновых кислот
AT0044185A AT394578B (de) 1984-02-17 1985-02-15 Verfahren zur herstellung von nucleinsaeure-reagenzien
CH725/85A CH671778A5 (sv) 1984-02-17 1985-02-15
SE8500733A SE463103B (sv) 1984-02-17 1985-02-15 Nukleinsyrareagens bestaaende av minst tvaa serier av minst tvaa uppsaettningar nukleinsyrafragment vilka inte aer homologa till varandra samt saett foer dessas framstaellning
DE3505287A DE3505287C2 (de) 1984-02-17 1985-02-15 Verbesserte Nucleinsäure-Reagenzien und Verfahren zu ihrer Herstellung
JP60029207A JPS60188100A (ja) 1984-02-17 1985-02-15 核酸試薬
HU85570A HU194938B (en) 1984-02-17 1985-02-15 Process for preparing improved nucleinic acid reagents
GB08503900A GB2156074B (en) 1984-02-17 1985-02-15 Improved nucleic acid reagents and methods for their preparation
FR858502188A FR2559783B1 (fr) 1984-02-17 1985-02-15 Reactifs d'acide nucleique perfectionnes et procedes pour leur preparation
RO117684A RO92633B (ro) 1984-02-17 1985-02-18 Metoda de preparare a unui reactiv pentru identificarea acizilor nucleici

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FI840655A FI71768C (sv) 1984-02-17 1984-02-17 Förbättrade nykleinsyrareagenser och förfarande för deras framställni ng.
FI840655 1984-02-17

Publications (4)

Publication Number Publication Date
FI840655A0 FI840655A0 (fi) 1984-02-17
FI840655A FI840655A (fi) 1985-08-18
FI71768B true FI71768B (fi) 1986-10-31
FI71768C FI71768C (sv) 1987-02-09

Family

ID=8518568

Family Applications (1)

Application Number Title Priority Date Filing Date
FI840655A FI71768C (sv) 1984-02-17 1984-02-17 Förbättrade nykleinsyrareagenser och förfarande för deras framställni ng.

Country Status (22)

Country Link
US (1) US4731325A (sv)
JP (1) JPS60188100A (sv)
AT (1) AT394578B (sv)
AU (1) AU577568B2 (sv)
BE (1) BE901671A (sv)
CA (1) CA1248895A (sv)
CH (1) CH671778A5 (sv)
DE (1) DE3505287C2 (sv)
DK (1) DK174675B1 (sv)
FI (1) FI71768C (sv)
FR (1) FR2559783B1 (sv)
GB (1) GB2156074B (sv)
HU (1) HU194938B (sv)
IE (1) IE57652B1 (sv)
IT (1) IT1183184B (sv)
LU (1) LU85768A1 (sv)
NL (1) NL193663C (sv)
NO (1) NO166543C (sv)
RO (1) RO92633B (sv)
SE (1) SE463103B (sv)
SU (1) SU1523053A3 (sv)
ZA (1) ZA85511B (sv)

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GB2156074B (en) 1988-03-16
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BE901671A (fr) 1985-05-29
LU85768A1 (fr) 1985-07-24
RO92633A (ro) 1987-10-30
NO166543B (no) 1991-04-29
AT394578B (de) 1992-05-11
SU1523053A3 (ru) 1989-11-15
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FR2559783B1 (fr) 1990-03-02
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SE463103B (sv) 1990-10-08
DK58985A (da) 1985-08-18
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AU577568B2 (en) 1988-09-29
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SE8500733L (sv) 1985-08-18
DE3505287C2 (de) 1994-01-20
HU194938B (en) 1988-03-28
IE850202L (en) 1985-08-17
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CA1248895A (en) 1989-01-17
US4731325A (en) 1988-03-15
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ZA85511B (en) 1985-11-27
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