FI70009C - Foerfarande foer framstaellning av nya 1,5-disubstituerad-2-pyrrolidonfoereningar vilka har prostaglandinliknande biologiska egenskaper - Google Patents

Foerfarande foer framstaellning av nya 1,5-disubstituerad-2-pyrrolidonfoereningar vilka har prostaglandinliknande biologiska egenskaper Download PDF

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Publication number
FI70009C
FI70009C FI772376A FI772376A FI70009C FI 70009 C FI70009 C FI 70009C FI 772376 A FI772376 A FI 772376A FI 772376 A FI772376 A FI 772376A FI 70009 C FI70009 C FI 70009C
Authority
FI
Finland
Prior art keywords
pyrrolidone
ppm
compound
solution
solvent
Prior art date
Application number
FI772376A
Other languages
English (en)
Finnish (fi)
Other versions
FI772376A (pt
FI70009B (fi
Inventor
Albin James Nelson
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of FI772376A publication Critical patent/FI772376A/fi
Application granted granted Critical
Publication of FI70009B publication Critical patent/FI70009B/fi
Publication of FI70009C publication Critical patent/FI70009C/fi

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • C07D207/26—2-Pyrrolidones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
FI772376A 1976-08-06 1977-08-05 Foerfarande foer framstaellning av nya 1,5-disubstituerad-2-pyrrolidonfoereningar vilka har prostaglandinliknande biologiska egenskaper FI70009C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US71236276A 1976-08-06 1976-08-06
US71236276 1976-08-06

Publications (3)

Publication Number Publication Date
FI772376A FI772376A (pt) 1978-02-07
FI70009B FI70009B (fi) 1986-01-31
FI70009C true FI70009C (fi) 1986-09-12

Family

ID=24861795

Family Applications (1)

Application Number Title Priority Date Filing Date
FI772376A FI70009C (fi) 1976-08-06 1977-08-05 Foerfarande foer framstaellning av nya 1,5-disubstituerad-2-pyrrolidonfoereningar vilka har prostaglandinliknande biologiska egenskaper

Country Status (31)

Country Link
JP (2) JPS5321159A (pt)
AR (1) AR217080A1 (pt)
AT (1) AT362887B (pt)
AU (1) AU508007B2 (pt)
BE (1) BE857506A (pt)
BG (1) BG31073A3 (pt)
CA (1) CA1077948A (pt)
CH (1) CH624934A5 (pt)
CS (1) CS221269B2 (pt)
DD (2) DD136135A5 (pt)
DE (1) DE2735904A1 (pt)
DK (1) DK352077A (pt)
ES (2) ES461388A1 (pt)
FI (1) FI70009C (pt)
FR (1) FR2369260A1 (pt)
GB (2) GB1556569A (pt)
GR (1) GR68688B (pt)
HU (1) HU180273B (pt)
IE (1) IE45505B1 (pt)
IL (1) IL52615A (pt)
LU (1) LU77936A1 (pt)
NL (1) NL7708637A (pt)
NO (1) NO772752L (pt)
NZ (1) NZ184806A (pt)
PH (1) PH17398A (pt)
PL (2) PL200124A1 (pt)
PT (1) PT66891B (pt)
SE (1) SE423813B (pt)
SU (3) SU703016A3 (pt)
YU (1) YU192577A (pt)
ZA (1) ZA774704B (pt)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5695569A (en) * 1979-12-27 1981-08-03 Canon Inc Forming method for bar lens sphere face
US4321201A (en) * 1980-09-22 1982-03-23 E. I. Du Pont De Nemours And Company Optically active tert-alkyl 7-(2-oxo-5-carbonyloxypyrrolidinyl) heptanoates
JPS59137224A (ja) * 1983-01-25 1984-08-07 Mitsubishi Electric Corp 電気鉄道用き電電圧補償装置
ATE327751T1 (de) 2000-01-31 2006-06-15 Pfizer Prod Inc Verwendung von aktivatoren des prostaglandinrezeptores 4 zur behandlung von akuter oder chronischer niereninsuffizienz
WO2002024647A1 (fr) * 2000-09-21 2002-03-28 Ono Pharmaceutical Co., Ltd. Agonistes du recepteur de l'ep4 comprenant comme principe actif des derives de la 8-azaprostaglandine
SK5562003A3 (en) * 2000-11-27 2004-08-03 Pfizer Prod Inc EP4 receptor selective agonists in the treatment of osteoporosis
IL159996A0 (en) * 2001-07-23 2004-06-20 Ono Pharmaceutical Co Remedies for diseases with bone mass loss having ep4 agonist as the active ingredient
BR0308738A (pt) * 2002-03-18 2005-01-11
US6573294B1 (en) * 2002-05-14 2003-06-03 Allergan, Inc. 8-azaprostaglandin analogs as agents for lowering intraocular pressure
WO2004065365A1 (ja) * 2003-01-21 2004-08-05 Ono Pharmaceutical Co., Ltd. ８−アザプロスタグランジン誘導体およびその医薬用途

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1386146A (en) * 1972-05-03 1975-03-05 Ici Ltd Cyclopentane derivatives
JPS511460A (en) * 1974-06-24 1976-01-08 Tanabe Seiyaku Co 22 piroridonjudotaino seiho
JPS514166A (ja) * 1974-06-28 1976-01-14 Tanabe Seiyaku Co 22piroridonjudotaino seiho
US3975399A (en) * 1974-08-06 1976-08-17 E. I. Du Pont De Nemours And Company 1,5-Disubstituted-2-pyrrolidinones, -3-pyrrolin-2-ones, and -4-pyrrolin-2-ones
DE2528664A1 (de) * 1975-06-27 1977-01-13 Hoechst Ag Pyrrolidone und verfahren zu ihrer herstellung

Also Published As

Publication number Publication date
JPS585196B2 (ja) 1983-01-29
AR217080A1 (es) 1980-02-29
IE45505B1 (en) 1982-09-08
ATA579477A (de) 1980-11-15
FR2369260B1 (pt) 1982-02-12
GB1556570A (en) 1979-11-28
CS221269B2 (en) 1983-04-29
PL112931B1 (en) 1980-11-29
AT362887B (de) 1981-06-25
GB1556569A (en) 1979-11-28
DK352077A (da) 1978-02-07
AU508007B2 (en) 1980-03-06
JPS5555161A (en) 1980-04-22
SU818480A3 (ru) 1981-03-30
ES461388A1 (es) 1978-12-01
IL52615A (en) 1981-09-13
CA1077948A (en) 1980-05-20
HU180273B (en) 1983-02-28
PL200124A1 (pl) 1978-05-22
NL7708637A (nl) 1978-02-08
DE2735904A1 (de) 1978-02-09
NO772752L (no) 1978-02-07
NZ184806A (en) 1980-04-28
GR68688B (pt) 1982-02-01
YU192577A (en) 1983-04-30
IE45505L (en) 1978-02-06
FI772376A (pt) 1978-02-07
FR2369260A1 (fr) 1978-05-26
IL52615A0 (en) 1977-10-31
JPS5531147B2 (pt) 1980-08-15
ZA774704B (en) 1978-06-28
SU703016A3 (ru) 1979-12-05
SU850000A3 (ru) 1981-07-23
LU77936A1 (pt) 1978-04-27
SE7708642L (sv) 1978-02-07
PT66891A (en) 1977-09-01
DD136135A5 (de) 1979-06-20
BE857506A (fr) 1978-02-06
ES471349A1 (es) 1979-09-16
DD143768A5 (de) 1980-09-10
BG31073A3 (en) 1981-10-15
SE423813B (sv) 1982-06-07
CH624934A5 (pt) 1981-08-31
FI70009B (fi) 1986-01-31
PT66891B (en) 1979-01-26
JPS5321159A (en) 1978-02-27
PH17398A (en) 1984-08-08
AU2751577A (en) 1979-02-08

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MM Patent lapsed

Owner name: PFIZER INC.